Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 158421951

GI number: 158421951

Start: 376702

End: 379092

Strand: Reverse

Name: aceE [H]

Synonym: AZC_0327

Alternate gene names: 158421951

Gene position: 379092-376702 (Counterclockwise)

Preceding gene: 158421953

Following gene: 158421950

Centisome position: 7.06

GC content: 69.22

Gene sequence:

>2391_bases
GTGACCACGGCGCAAGAGCTGGAGATCCTCGCCGAACTGGAGCGCAAGGCGCTCTGGCTCGCCAGCTGGACCATCCACAA
TGCCAACCACCTGCGCCCCTCCACGGATGGCCTCAAGGTGGGCGGGCATCAGGCGTCCTCCGCCTCGCTCGCCACGATCA
TGACCGCGCTCTACTTCCACACCCTCCGGCCACAGGACCGGGTAGCGGTGAAGCCGCACGCGAGCCCCATCTTCCATGCC
ATCCAGTATCTGCTCGGCGCCCAAACGCGCGAGAAGCTGGAGGCGTTCCGCGCCTATAAGGGCGCCCAGTCCTATCCCTC
CCGCACCAAGGATACGGACGACGTGGACTTCTCCACCGGCTCCGTGGGCCTCGGGGTCGCGCAGACGCTGTTCGCCTCGC
TGGCGCAGGATTATGTGCGCGCCCACGGCCTCACCGATCGGCCGGAGGGCCGCATGATCGCCCTCGTGGGCGATGCGGAA
CTGGACGAGGGCAATGTGTTCGAGGCCCTGCTGGAGGGCTGGAAGCACGACGTGCGCAACACCTGGTGGATCGTCGATTA
CAACCGCCAGAGCCTCGATGCCGTGGTGCGCGAGGGTCTGTACGAGCGCTTCATCGGCATCTTCGAGGCCATGGGCTGGC
AGGTGGTCGTGCTCAAATACGGCTCGCTCCAGCAGGCCGCCTTCCGCGAGCCCGGCGGCGAGAAGCTGCGCCACTGGATC
GACACCTGCCCGAACGGCGAATATTCCGCCCTCACCTTCCAGGGCGGCGCGGCGTGGCGCAAGCGCCTGATGGATGATCT
GGGCGATCAGGGCGACGTGACCCGCCTCGTCGAGGCGCGCTCGGATGCCGAACTCTCCGCCCTGATGACCAATCTGGGCG
GACACGACCTGCCGACCATCCTCGACGCCTTCGACGGCATCGACCACGACCGGCCGGTCTGCTTCCTCTGCTACACGGTG
AAGGGCTTCGGCCTGCCGCTCGCCGGCCACAAGGACAATCACGCCGGCCTCATGACGCCGACGCAGATGGACACGCTGCG
CGCCGCCATGAACATCCGCGCGGGCCATGAGTGGGACCGCTTCGAGGGGCTCACCCTGCCGCCCGCGACGCTGGAGCGTT
TCCTGAAGGACGTGCCCTTCCGCCGCGAGGGCACCCGGCGCTATTCCGACGCTGCGCTGGCCGTCCCGTCCATCGCGCCG
CCGCCCAATGCCTCGCTCTCCACGCAGGCCGGCTTCGGCCTCATCCTTCAGGATCTGGCGCGGGGCGACAGCGCGCTCGC
GAGCCGCATCGTCACAACCTCGCCGGACGTGACCGTCTCCACCAATCTCGGCCCGTGGGTGAACCGGCGCGGCCTCTTCG
CCCAGCGGGAGCTGGCGGACGTGTTCAAGCGCGAGCGCATCCCCTCCACCTTCAACTGGGAGTTCTCGCCGGACGGGCAG
CACATGGAACTGGGCATCGCCGAGATGAACCTGTTCCTCATGCTCTCGGCCCTCGGCCTCTCCCACTCGCTGTTCGGTGC
CCGGCTCATCCCCGTGGGCACGCTCTACGACCCCTTCATCTGCCGGGGTCTCGATGCCCTGAACTATGCCTGCTATCAGG
ACGCCCGCTTCATCCTCGTGGCCACCCCGTCCGGCATCACGCTGGCGCCGGAGGGCGGAGCGCACCAGTCCATCGCCACC
CCGCTCATCGGCATGTCGCAGGATGGGCTTGCCGCCTTCGAGCCGGCCTTCGTGGACGAACTGGCGGTGCTGGTGGAATT
CGCCTTCGATTACGTGCAGCGTGACGGCGGCGGCCCGGACGAGGCCCGCAACTGGCTGCGGGACGAGACCGGCGGCTCGG
TCTATTTCCGCCTCTCCACCCGCGCGCTGGAACAGCCCCGCCGCGCCTTCACGCAAACCCAGAAGCGGCACATGGTGGAC
GGCGCCTATTGGCTGCGTGAGCCCGGACCCAACGCGGAGGTGGTGATCGCCGTGCAGGGCGCGCTGGCGCCGGAAGCCAT
CGAGGCGGTGGGCCTGATCGCCGAGGACCGGCGGGACGTCGGCCTGCTCATGGTCACCTCCGCCGACCGGCTGAACGCCG
GCTGGACCGCCGCGTCACGGGCGCGCGAGCAGGGCCATTACAGCGCCGAGAGCCATGTGGAGCGCCTGCTGGCGCCCCTG
CCCCGCCATTGCGGGCTGGTGAGCGTGATCGACGGCCATCCCGCGACGCTCGGCTGGCTCGGCTCGGTGATGGGCCACCG
GCAGCGGGCGCTGGGTGTCGAGCATTTCGGCCAGACCGGCAGCCTGCAGGATCTCTATCGCCACCATGGCGTCGATGCGG
CTGCCATCGTCTCGGCCGCGCAGGCCATCGCGCCCGGCCGCCCCATGCGCCACCTCAGGGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CGGAGGATAGATCGGCAAGAACCACCCGCTGGACGGCGCTATCCTCCCGGAACCGCCTCTCGCGCGGCACCAAGAAGCAG
ACCATCCGGAGGACGACATC

Downstream 100 bases:

>100_bases
GGAGCGCCCGCCATCGCCGCGAGGGCCGAGCCGAACAGGAGAGCCGAGCCCCCCCAGCGCCACGGCGGCGCTGCGGGAAA
TCCCGAGCGGGGTGGCAAAG

Product: pyruvate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MTTAQELEILAELERKALWLASWTIHNANHLRPSTDGLKVGGHQASSASLATIMTALYFHTLRPQDRVAVKPHASPIFHA
IQYLLGAQTREKLEAFRAYKGAQSYPSRTKDTDDVDFSTGSVGLGVAQTLFASLAQDYVRAHGLTDRPEGRMIALVGDAE
LDEGNVFEALLEGWKHDVRNTWWIVDYNRQSLDAVVREGLYERFIGIFEAMGWQVVVLKYGSLQQAAFREPGGEKLRHWI
DTCPNGEYSALTFQGGAAWRKRLMDDLGDQGDVTRLVEARSDAELSALMTNLGGHDLPTILDAFDGIDHDRPVCFLCYTV
KGFGLPLAGHKDNHAGLMTPTQMDTLRAAMNIRAGHEWDRFEGLTLPPATLERFLKDVPFRREGTRRYSDAALAVPSIAP
PPNASLSTQAGFGLILQDLARGDSALASRIVTTSPDVTVSTNLGPWVNRRGLFAQRELADVFKRERIPSTFNWEFSPDGQ
HMELGIAEMNLFLMLSALGLSHSLFGARLIPVGTLYDPFICRGLDALNYACYQDARFILVATPSGITLAPEGGAHQSIAT
PLIGMSQDGLAAFEPAFVDELAVLVEFAFDYVQRDGGGPDEARNWLRDETGGSVYFRLSTRALEQPRRAFTQTQKRHMVD
GAYWLREPGPNAEVVIAVQGALAPEAIEAVGLIAEDRRDVGLLMVTSADRLNAGWTAASRAREQGHYSAESHVERLLAPL
PRHCGLVSVIDGHPATLGWLGSVMGHRQRALGVEHFGQTGSLQDLYRHHGVDAAAIVSAAQAIAPGRPMRHLRALG

Sequences:

>Translated_796_residues
MTTAQELEILAELERKALWLASWTIHNANHLRPSTDGLKVGGHQASSASLATIMTALYFHTLRPQDRVAVKPHASPIFHA
IQYLLGAQTREKLEAFRAYKGAQSYPSRTKDTDDVDFSTGSVGLGVAQTLFASLAQDYVRAHGLTDRPEGRMIALVGDAE
LDEGNVFEALLEGWKHDVRNTWWIVDYNRQSLDAVVREGLYERFIGIFEAMGWQVVVLKYGSLQQAAFREPGGEKLRHWI
DTCPNGEYSALTFQGGAAWRKRLMDDLGDQGDVTRLVEARSDAELSALMTNLGGHDLPTILDAFDGIDHDRPVCFLCYTV
KGFGLPLAGHKDNHAGLMTPTQMDTLRAAMNIRAGHEWDRFEGLTLPPATLERFLKDVPFRREGTRRYSDAALAVPSIAP
PPNASLSTQAGFGLILQDLARGDSALASRIVTTSPDVTVSTNLGPWVNRRGLFAQRELADVFKRERIPSTFNWEFSPDGQ
HMELGIAEMNLFLMLSALGLSHSLFGARLIPVGTLYDPFICRGLDALNYACYQDARFILVATPSGITLAPEGGAHQSIAT
PLIGMSQDGLAAFEPAFVDELAVLVEFAFDYVQRDGGGPDEARNWLRDETGGSVYFRLSTRALEQPRRAFTQTQKRHMVD
GAYWLREPGPNAEVVIAVQGALAPEAIEAVGLIAEDRRDVGLLMVTSADRLNAGWTAASRAREQGHYSAESHVERLLAPL
PRHCGLVSVIDGHPATLGWLGSVMGHRQRALGVEHFGQTGSLQDLYRHHGVDAAAIVSAAQAIAPGRPMRHLRALG
>Mature_795_residues
TTAQELEILAELERKALWLASWTIHNANHLRPSTDGLKVGGHQASSASLATIMTALYFHTLRPQDRVAVKPHASPIFHAI
QYLLGAQTREKLEAFRAYKGAQSYPSRTKDTDDVDFSTGSVGLGVAQTLFASLAQDYVRAHGLTDRPEGRMIALVGDAEL
DEGNVFEALLEGWKHDVRNTWWIVDYNRQSLDAVVREGLYERFIGIFEAMGWQVVVLKYGSLQQAAFREPGGEKLRHWID
TCPNGEYSALTFQGGAAWRKRLMDDLGDQGDVTRLVEARSDAELSALMTNLGGHDLPTILDAFDGIDHDRPVCFLCYTVK
GFGLPLAGHKDNHAGLMTPTQMDTLRAAMNIRAGHEWDRFEGLTLPPATLERFLKDVPFRREGTRRYSDAALAVPSIAPP
PNASLSTQAGFGLILQDLARGDSALASRIVTTSPDVTVSTNLGPWVNRRGLFAQRELADVFKRERIPSTFNWEFSPDGQH
MELGIAEMNLFLMLSALGLSHSLFGARLIPVGTLYDPFICRGLDALNYACYQDARFILVATPSGITLAPEGGAHQSIATP
LIGMSQDGLAAFEPAFVDELAVLVEFAFDYVQRDGGGPDEARNWLRDETGGSVYFRLSTRALEQPRRAFTQTQKRHMVDG
AYWLREPGPNAEVVIAVQGALAPEAIEAVGLIAEDRRDVGLLMVTSADRLNAGWTAASRAREQGHYSAESHVERLLAPLP
RHCGLVSVIDGHPATLGWLGSVMGHRQRALGVEHFGQTGSLQDLYRHHGVDAAAIVSAAQAIAPGRPMRHLRALG

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=829, Percent_Identity=25.0904704463209, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 87291; Mature: 87160

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQELEILAELERKALWLASWTIHNANHLRPSTDGLKVGGHQASSASLATIMTALYFH
CCCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHH
TLRPQDRVAVKPHASPIFHAIQYLLGAQTREKLEAFRAYKGAQSYPSRTKDTDDVDFSTG
HCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SVGLGVAQTLFASLAQDYVRAHGLTDRPEGRMIALVGDAELDEGNVFEALLEGWKHDVRN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TWWIVDYNRQSLDAVVREGLYERFIGIFEAMGWQVVVLKYGSLQQAAFREPGGEKLRHWI
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHHHH
DTCPNGEYSALTFQGGAAWRKRLMDDLGDQGDVTRLVEARSDAELSALMTNLGGHDLPTI
HCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHH
LDAFDGIDHDRPVCFLCYTVKGFGLPLAGHKDNHAGLMTPTQMDTLRAAMNIRAGHEWDR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
FEGLTLPPATLERFLKDVPFRREGTRRYSDAALAVPSIAPPPNASLSTQAGFGLILQDLA
CCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHH
RGDSALASRIVTTSPDVTVSTNLGPWVNRRGLFAQRELADVFKRERIPSTFNWEFSPDGQ
CCHHHHHHHHEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCC
HMELGIAEMNLFLMLSALGLSHSLFGARLIPVGTLYDPFICRGLDALNYACYQDARFILV
EEEEHHHHHHHHHHHHHHHCHHHHHCCEEEECCCHHCHHHHHCHHHHHHHHHCCCCEEEE
ATPSGITLAPEGGAHQSIATPLIGMSQDGLAAFEPAFVDELAVLVEFAFDYVQRDGGGPD
ECCCCCEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
EARNWLRDETGGSVYFRLSTRALEQPRRAFTQTQKRHMVDGAYWLREPGPNAEVVIAVQG
HHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCEEEEEEEC
ALAPEAIEAVGLIAEDRRDVGLLMVTSADRLNAGWTAASRAREQGHYSAESHVERLLAPL
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHC
PRHCGLVSVIDGHPATLGWLGSVMGHRQRALGVEHFGQTGSLQDLYRHHGVDAAAIVSAA
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHCCCCHHHHHHHH
QAIAPGRPMRHLRALG
HHHCCCCHHHHHHCCC
>Mature Secondary Structure 
TTAQELEILAELERKALWLASWTIHNANHLRPSTDGLKVGGHQASSASLATIMTALYFH
CCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHH
TLRPQDRVAVKPHASPIFHAIQYLLGAQTREKLEAFRAYKGAQSYPSRTKDTDDVDFSTG
HCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SVGLGVAQTLFASLAQDYVRAHGLTDRPEGRMIALVGDAELDEGNVFEALLEGWKHDVRN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TWWIVDYNRQSLDAVVREGLYERFIGIFEAMGWQVVVLKYGSLQQAAFREPGGEKLRHWI
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHHHH
DTCPNGEYSALTFQGGAAWRKRLMDDLGDQGDVTRLVEARSDAELSALMTNLGGHDLPTI
HCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHH
LDAFDGIDHDRPVCFLCYTVKGFGLPLAGHKDNHAGLMTPTQMDTLRAAMNIRAGHEWDR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
FEGLTLPPATLERFLKDVPFRREGTRRYSDAALAVPSIAPPPNASLSTQAGFGLILQDLA
CCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHH
RGDSALASRIVTTSPDVTVSTNLGPWVNRRGLFAQRELADVFKRERIPSTFNWEFSPDGQ
CCHHHHHHHHEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCC
HMELGIAEMNLFLMLSALGLSHSLFGARLIPVGTLYDPFICRGLDALNYACYQDARFILV
EEEEHHHHHHHHHHHHHHHCHHHHHCCEEEECCCHHCHHHHHCHHHHHHHHHCCCCEEEE
ATPSGITLAPEGGAHQSIATPLIGMSQDGLAAFEPAFVDELAVLVEFAFDYVQRDGGGPD
ECCCCCEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
EARNWLRDETGGSVYFRLSTRALEQPRRAFTQTQKRHMVDGAYWLREPGPNAEVVIAVQG
HHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCEEEEEEEC
ALAPEAIEAVGLIAEDRRDVGLLMVTSADRLNAGWTAASRAREQGHYSAESHVERLLAPL
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHC
PRHCGLVSVIDGHPATLGWLGSVMGHRQRALGVEHFGQTGSLQDLYRHHGVDAAAIVSAA
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHCCCCHHHHHHHH
QAIAPGRPMRHLRALG
HHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]