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The map label for this gene is ttuD [H]

Identifier: 158421948

GI number: 158421948

Start: 373684

End: 375096

Strand: Direct

Name: ttuD [H]

Synonym: AZC_0324

Alternate gene names: 158421948

Gene position: 373684-375096 (Clockwise)

Preceding gene: 158421945

Following gene: 158421949

Centisome position: 6.96

GC content: 69.64

Gene sequence:

>1413_bases
TTGTTTTGCTTTGGGAGTGAGGCTATCGCCTCTCCGGCCAAAGGCCAGAGGCTTTTGCGGGCCTTCGACGAATTTCCCAT
GGTGAGCGCTGGCGGAGCCGCGGCGGCGTTGCCCTCGGCCTGCGCGCGCGCTAGGACTATTGGCATAAAGTATACAAAGG
GGAACGCCATGCCGTCCGATCGGGACATCCTGCTCGCCCTGTTCGATGCCGCGCTGAATGCCGCCGTGCCCGAGGGCAAG
TTCGAGGGCCGCCTGCCGGAGCCGCCGAAGGGGCGCACCATCGTGATCGGCGCCGGCAAGGCGTCCGCCCGCATGGCGCG
GGCCTTCGAGGCGGCGTGGGGACGGCCCTGCGAGGGCCTGATCGTGACCCGCTACGGCCATGGCTGCGAGACGCAGCATA
TCGAGATTGTGGAAGCCGCCCATCCGGTGCCCGATCAGGCCGGGCTCGATGCCGCACGTCGCATTCTGGAACTCGCCCGC
TCCGCGGGACCGGATGATCTCGTGGTGTGCCTCATGTCCGGCGGCGCCTCGGCGCTTCTGACGCTGCCGGCCGAGGGGCT
GACGCTGGCTGACAAGCAGGCGCTGAACAAGCAGCTTCTGAAGTCCGGCGCGCCCATCGGCATCATGAACCGGGTGCGCA
AGTCCGTCTCCGCCATCAAGGGCGGGCGGCTGGCAGCCGCCATCGCGCCCGCGCGGGCCGTGACCTATCTCATCTCCGAC
GTGCCGGGGGACGACCCCGCGGCCATCGGCTCCGGCCCCACTATTCCCGAGGCCTCGGACCCGGAAGAGGTGCTGCGCCT
CATGCGGGCCTGGGGCATCGAGGCGAGCCCGGAGCTTGAGGCCGTCATCCGCGCCAATGTGGTCTCCGGCGAGGCCCTGC
CCGGGCAGGAGGTGCACATGATCGCGACCCCGCTCATGGCGCTTCAGGCGGCGGAAGCCAAAGCCCGCGACTTCGGTCTC
ACCCCTCTCATTCTCGGGGACGCCATCGAGGGCGAGGCGCGCGAGGCGGCGAACGTCTTCGCCGGCATCTCCCGCTCGGC
GGCCACCCATGGCCTGCCGGTGAAGGCGCCCTGCGTGCTGCTCTCGGGCGGCGAGACCACCGTCACGGTGCGCGGCAAGG
GGCGCGGCGGGCGCAATGTGGAGTTCCTGCTGGCGCTCGCCCTCGCGCTGAAGGGCGAGGCCGGTCTCAGCGCCATCGCC
TGCGACACGGACGGGGTGGACGGCACGGAGGACAATGCGGGGGCGTGGTTCGACGCGGCCATTCTGGAAGAGGCCCGCGC
CAAGGGCCTCTCGGCCGATGCCTTCCTCGCCAACAATGACGGCTACAGCTTCTTCGCGGCGCTGGACCGGTTGGTGGTGA
CGGGGCCGACACTGACCAACGTCAACGACTTCCGCGCCATCCTCATTCGCTGA

Upstream 100 bases:

>100_bases
TGTTGATGAAGTCTGCCCGCGCCGCAAGCGGGGAGAGGGCGAAAACGGCTGCAAGCGCAGCAAGCGCGAGTTTTCTCAAG
GGCGTTCTCCCAAATCAGTT

Downstream 100 bases:

>100_bases
GCCGGCTCTGCTCCATAGCCGACAATGTTGCATGTTGCTGCGGCGCAGCAGGGCTGCGCCGTTCGCATGGCCTTTGTGAA
GCTCTGATATATCAGCCGCT

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MFCFGSEAIASPAKGQRLLRAFDEFPMVSAGGAAAALPSACARARTIGIKYTKGNAMPSDRDILLALFDAALNAAVPEGK
FEGRLPEPPKGRTIVIGAGKASARMARAFEAAWGRPCEGLIVTRYGHGCETQHIEIVEAAHPVPDQAGLDAARRILELAR
SAGPDDLVVCLMSGGASALLTLPAEGLTLADKQALNKQLLKSGAPIGIMNRVRKSVSAIKGGRLAAAIAPARAVTYLISD
VPGDDPAAIGSGPTIPEASDPEEVLRLMRAWGIEASPELEAVIRANVVSGEALPGQEVHMIATPLMALQAAEAKARDFGL
TPLILGDAIEGEAREAANVFAGISRSAATHGLPVKAPCVLLSGGETTVTVRGKGRGGRNVEFLLALALALKGEAGLSAIA
CDTDGVDGTEDNAGAWFDAAILEEARAKGLSADAFLANNDGYSFFAALDRLVVTGPTLTNVNDFRAILIR

Sequences:

>Translated_470_residues
MFCFGSEAIASPAKGQRLLRAFDEFPMVSAGGAAAALPSACARARTIGIKYTKGNAMPSDRDILLALFDAALNAAVPEGK
FEGRLPEPPKGRTIVIGAGKASARMARAFEAAWGRPCEGLIVTRYGHGCETQHIEIVEAAHPVPDQAGLDAARRILELAR
SAGPDDLVVCLMSGGASALLTLPAEGLTLADKQALNKQLLKSGAPIGIMNRVRKSVSAIKGGRLAAAIAPARAVTYLISD
VPGDDPAAIGSGPTIPEASDPEEVLRLMRAWGIEASPELEAVIRANVVSGEALPGQEVHMIATPLMALQAAEAKARDFGL
TPLILGDAIEGEAREAANVFAGISRSAATHGLPVKAPCVLLSGGETTVTVRGKGRGGRNVEFLLALALALKGEAGLSAIA
CDTDGVDGTEDNAGAWFDAAILEEARAKGLSADAFLANNDGYSFFAALDRLVVTGPTLTNVNDFRAILIR
>Mature_470_residues
MFCFGSEAIASPAKGQRLLRAFDEFPMVSAGGAAAALPSACARARTIGIKYTKGNAMPSDRDILLALFDAALNAAVPEGK
FEGRLPEPPKGRTIVIGAGKASARMARAFEAAWGRPCEGLIVTRYGHGCETQHIEIVEAAHPVPDQAGLDAARRILELAR
SAGPDDLVVCLMSGGASALLTLPAEGLTLADKQALNKQLLKSGAPIGIMNRVRKSVSAIKGGRLAAAIAPARAVTYLISD
VPGDDPAAIGSGPTIPEASDPEEVLRLMRAWGIEASPELEAVIRANVVSGEALPGQEVHMIATPLMALQAAEAKARDFGL
TPLILGDAIEGEAREAANVFAGISRSAATHGLPVKAPCVLLSGGETTVTVRGKGRGGRNVEFLLALALALKGEAGLSAIA
CDTDGVDGTEDNAGAWFDAAILEEARAKGLSADAFLANNDGYSFFAALDRLVVTGPTLTNVNDFRAILIR

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=481, Percent_Identity=30.1455301455301, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI193205461, Length=411, Percent_Identity=29.683698296837, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19920578, Length=375, Percent_Identity=32.8, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 48581; Mature: 48581

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCFGSEAIASPAKGQRLLRAFDEFPMVSAGGAAAALPSACARARTIGIKYTKGNAMPSD
CCEECCHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
RDILLALFDAALNAAVPEGKFEGRLPEPPKGRTIVIGAGKASARMARAFEAAWGRPCEGL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCE
IVTRYGHGCETQHIEIVEAAHPVPDQAGLDAARRILELARSAGPDDLVVCLMSGGASALL
EEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
TLPAEGLTLADKQALNKQLLKSGAPIGIMNRVRKSVSAIKGGRLAAAIAPARAVTYLISD
EECCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHC
VPGDDPAAIGSGPTIPEASDPEEVLRLMRAWGIEASPELEAVIRANVVSGEALPGQEVHM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHEEEEECCCCCCCCCCHH
IATPLMALQAAEAKARDFGLTPLILGDAIEGEAREAANVFAGISRSAATHGLPVKAPCVL
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LSGGETTVTVRGKGRGGRNVEFLLALALALKGEAGLSAIACDTDGVDGTEDNAGAWFDAA
EECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
ILEEARAKGLSADAFLANNDGYSFFAALDRLVVTGPTLTNVNDFRAILIR
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MFCFGSEAIASPAKGQRLLRAFDEFPMVSAGGAAAALPSACARARTIGIKYTKGNAMPSD
CCEECCHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
RDILLALFDAALNAAVPEGKFEGRLPEPPKGRTIVIGAGKASARMARAFEAAWGRPCEGL
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCE
IVTRYGHGCETQHIEIVEAAHPVPDQAGLDAARRILELARSAGPDDLVVCLMSGGASALL
EEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
TLPAEGLTLADKQALNKQLLKSGAPIGIMNRVRKSVSAIKGGRLAAAIAPARAVTYLISD
EECCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHC
VPGDDPAAIGSGPTIPEASDPEEVLRLMRAWGIEASPELEAVIRANVVSGEALPGQEVHM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHEEEEECCCCCCCCCCHH
IATPLMALQAAEAKARDFGLTPLILGDAIEGEAREAANVFAGISRSAATHGLPVKAPCVL
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LSGGETTVTVRGKGRGGRNVEFLLALALALKGEAGLSAIACDTDGVDGTEDNAGAWFDAA
EECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
ILEEARAKGLSADAFLANNDGYSFFAALDRLVVTGPTLTNVNDFRAILIR
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]