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The map label for this gene is nudG [H]

Identifier: 158421939

GI number: 158421939

Start: 364522

End: 364926

Strand: Direct

Name: nudG [H]

Synonym: AZC_0315

Alternate gene names: 158421939

Gene position: 364522-364926 (Clockwise)

Preceding gene: 158421938

Following gene: 158421940

Centisome position: 6.79

GC content: 67.65

Gene sequence:

>405_bases
GTGAAGATCACGCTCGTCGCCGCCTGCGCGCTGGTGGATGCCGACAACCGGGTGCTGGTGGCCCAGCGCCCGGAAGGCAA
GGCGCTGGCCGGCCTCTGGGAGTTCCCCGGCGGCAAGGTGGAGCCCGGCGAGCGGCCCGAAGCCTGCCTCATCCGGGAAT
TGCATGAGGAACTCGGCATCACGGTGAAGGAGGCGTGCCTTGCGCCCCTCACCTTTGCCAGCCACGGCTATGAGACCTTC
CATCTGCTGATGCCGCTGTGGATCTGCCGCCGTTGGGAAGGGCAGGTCATCGCTCGTGAGCACAAGGCGCTGAAGTGGCT
GCGCGCAGGCAAGCTGCGCGACATCCCCATGCCGCCGGCGGACGAACCGCTCATTCCGCCGCTGATCGACCTTCTCGGTC
CCTGA

Upstream 100 bases:

>100_bases
TCGACATCCGCGTGGACCTCGGCCTCGGCAAGGGGGCGGATCGCGTCCTGACCTGCGATCTGACCAAGGAATACGTGGCC
ATCAACGGCGATTACCGCTC

Downstream 100 bases:

>100_bases
AGCGGCGGCCGCATGGGTGTGCGGCTGATTCAAGGTTTTTCTTCAAGTATTTATAGATGAGTGTCCCGTCTGCTCGGTCC
GCCCGCAGCGTGCGGTGCGG

Product: NTP pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGITVKEACLAPLTFASHGYETF
HLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPADEPLIPPLIDLLGP

Sequences:

>Translated_134_residues
MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGITVKEACLAPLTFASHGYETF
HLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPADEPLIPPLIDLLGP
>Mature_134_residues
MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGITVKEACLAPLTFASHGYETF
HLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPADEPLIPPLIDLLGP

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=133, Percent_Identity=41.3533834586466, Blast_Score=83, Evalue=8e-18,
Organism=Escherichia coli, GI1786288, Length=130, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14903; Mature: 14903

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGI
CEEEEEEEEEEECCCCEEEEEECCCCCEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHCC
TVKEACLAPLTFASHGYETFHLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DEPLIPPLIDLLGP
CCCCCCHHHHHHCC
>Mature Secondary Structure
MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGI
CEEEEEEEEEEECCCCEEEEEECCCCCEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHCC
TVKEACLAPLTFASHGYETFHLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DEPLIPPLIDLLGP
CCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]