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The map label for this gene is cph2 [H]

Identifier: 158421932

GI number: 158421932

Start: 358070

End: 359770

Strand: Reverse

Name: cph2 [H]

Synonym: AZC_0308

Alternate gene names: 158421932

Gene position: 359770-358070 (Counterclockwise)

Preceding gene: 158421933

Following gene: 158421930

Centisome position: 6.7

GC content: 69.61

Gene sequence:

>1701_bases
GTGGCCGGTCGCAATCCTAGCTCGCCCGTGACGCCGGCTCCCCCTGCCGGCGAGCCCAAAACTGTGCTCGATACGCCCGA
ACAGACCCTTCAGGCCCTGCAGACCTTGCAGTGTCTCGTCTATCGCTGGGATCTCACCGCCAACACCGTTCACTGGAGCG
CCAACAGCGGCGAAGCCCTCGGGCCGGCGCTGCTGGAGCAGCTCGGCCGCGGCACGACGTTTCGCGCCTTCCTCGGCTGC
ACGGACGAGAGCACCGACTACCACCGCTTCGCGCGCGCCCTGCCACTGGCCAGCATGCCCTACGAGGCGCTGGTCCGGCC
GGCGATCGACGGCACGCCCGCAGCCTTCCGCGTCCATGACCAGGGCCGCTGGCGGGCGGGCAGCGACGGCCAGCCGGAGC
AGGCGGTCGGCACGCTGGAGATCCTCCCCCTCCTCGCCCCGGTCATCCCGGGCGGGACCGCGGACCCGCTCACGGGCGCA
CTCACCCGCCGGCATCTCACGGAGGCCCTCGGCACCCTCCCCTTCGGACCGCAGGCGCGCTGGGCGCTGCTGCTCGTGGG
ACTCGATGACCTCGGCCGGATCAACGACCGCTTCGGCTTCGAGACCGCCGACCGGCTTCTGGTGGCGCTGGCGGGCCGGC
TGCGCCAGCAGCTCTCCAGCGCCGATCTGCTGCTGCGCTTCTCCGGCAACAAGTTCGCCATTCTGCTGACCGAAACATCG
GTGGAGGCCCTCGGCGCGTTCGGTGAGCGGCTCATCTCCGAAATTCGCGAGGCGCGGCTCTCCGCCGGCGAGGGCCAACT
GCCGGTGAGCGTCACCATCGGCGCCATCCTGCCCCCGCACCAGGGCGAGGCGCCCGATGCGATCATCGCCCGCCTGCAGG
AAGCGCATGAGATGGCCAAGCGCCGGGGGCGCGGGCGCTTCTTCCTCGACCTGCAGGGCACACGGAACGAGGGCCGTCGC
CGGGCCAATCTGCAGATGGCCGACGAGATCGTTCAGGCCATCGACCGCAATGACGTCACGGTTGCCTACCAGCCCGTGGT
GCGCGCCACCACCCGCACCCTGGTGTTCTGCGAGGCGCTCGCCCGCATCGCCCACGACCGCTACTCGCGGCAGTATTCCG
GCCACCGTCTCGTGGCTGCGGCGGACTCCCTCGGCCTCATGGGCCATCTGGACCGCAGCATGCTGAAGCAGGTCGCCGCC
GACATGCGCCGCGACCCGACGCTGCACGTCTCGATCAACGTCTCCGCCTCCTCCATCATGGACGAGGCGTGGATCGCGCT
CTACCGACGGGAAGTGGACACGGACATCGGGCGCCGGCTCATCGTCGAACTGACGGAGTCGGTGGCGGTGGATCATCTCT
CGGCCGCGCGCAACTTCATCGCGCAGGTGCGCCCCTCCGGCGCACGCATCGCCATCGACGACTTCGGCGCCGGTGCCACA
TCCTTCCGCAACCTGCGCAAGCTCGGCGTCGATCTGGTGAAGATCGACGGCGGCTACATCATCAACATGGCAAAATCGCC
GGACGACCAGGCGTTCGTACGGGCGCTGCTCACCCTCTCCCGCCAACTGGGGATCGAGACCGTCGCGGAATGGGTGCAGA
ACGAGATCGTCGCCGCCCAGTTGCTCGAATGGGGGTGCGACTATTTCCAGGGCTCGCTGAGCGGGCTTGCGCGCCCGCTG
GCGACAGAGCACGGCACCTGA

Upstream 100 bases:

>100_bases
TTGATAGCCGCGCAATTGTACCTTTCGCACCTCTCGGGTTTCAGGGACAATTCACGCGCGAAAGCTGCGCGCATGGCTGG
AAAGGTCAAATGGAGTTCCG

Downstream 100 bases:

>100_bases
GGCCGCGGCGCCCGGTGCTGGCGCCTCCTTTAGGAAGGACTCTCTCGCCCGAAGGGGAACTGGCGCGCGATGGGCCGAAC
CCATCGCGCGGTTGTCGGAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MAGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEALGPALLEQLGRGTTFRAFLGC
TDESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHDQGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGA
LTRRHLTEALGTLPFGPQARWALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETS
VEALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAKRRGRGRFFLDLQGTRNEGRR
RANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEALARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAA
DMRRDPTLHVSINVSASSIMDEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGAT
SFRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQLLEWGCDYFQGSLSGLARPL
ATEHGT

Sequences:

>Translated_566_residues
MAGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEALGPALLEQLGRGTTFRAFLGC
TDESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHDQGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGA
LTRRHLTEALGTLPFGPQARWALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETS
VEALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAKRRGRGRFFLDLQGTRNEGRR
RANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEALARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAA
DMRRDPTLHVSINVSASSIMDEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGAT
SFRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQLLEWGCDYFQGSLSGLARPL
ATEHGT
>Mature_565_residues
AGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEALGPALLEQLGRGTTFRAFLGCT
DESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHDQGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGAL
TRRHLTEALGTLPFGPQARWALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETSV
EALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAKRRGRGRFFLDLQGTRNEGRRR
ANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEALARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAAD
MRRDPTLHVSINVSASSIMDEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGATS
FRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQLLEWGCDYFQGSLSGLARPLA
TEHGT

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=26.2910798122066, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081921, Length=419, Percent_Identity=24.3436754176611, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI226510982, Length=377, Percent_Identity=28.6472148541114, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787055, Length=389, Percent_Identity=24.4215938303342, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790496, Length=246, Percent_Identity=25.609756097561, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082096, Length=261, Percent_Identity=26.0536398467433, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=29.1845493562232, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081845, Length=215, Percent_Identity=28.3720930232558, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786507, Length=230, Percent_Identity=26.9565217391304, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788502, Length=239, Percent_Identity=28.0334728033473, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693134, Length=129, Percent_Identity=32.5581395348837, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87081881, Length=157, Percent_Identity=31.2101910828025, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081980, Length=248, Percent_Identity=24.1935483870968, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788381, Length=397, Percent_Identity=23.1738035264484, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 61643; Mature: 61512

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEAL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCC
GPALLEQLGRGTTFRAFLGCTDESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHD
CHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEC
QGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGALTRRHLTEALGTLPFGPQAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
WALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETS
EEEEEEECHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCC
VEALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
RRGRGRFFLDLQGTRNEGRRRANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEAL
HCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHH
ARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAADMRRDPTLHVSINVSASSIM
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
DEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
SFRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQ
HHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLEWGCDYFQGSLSGLARPLATEHGT
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEAL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCC
GPALLEQLGRGTTFRAFLGCTDESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHD
CHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEC
QGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGALTRRHLTEALGTLPFGPQAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
WALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETS
EEEEEEECHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCC
VEALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
RRGRGRFFLDLQGTRNEGRRRANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEAL
HCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHH
ARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAADMRRDPTLHVSINVSASSIM
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
DEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
SFRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQ
HHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLEWGCDYFQGSLSGLARPLATEHGT
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]