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The map label for this gene is hss [H]

Identifier: 158421920

GI number: 158421920

Start: 345015

End: 346445

Strand: Direct

Name: hss [H]

Synonym: AZC_0296

Alternate gene names: 158421920

Gene position: 345015-346445 (Clockwise)

Preceding gene: 158421919

Following gene: 158421921

Centisome position: 6.43

GC content: 66.67

Gene sequence:

>1431_bases
ATGAGCGCCTGGCCGGTTCACGCCACCATTGATGGACCCATCGTCATGATCGGCTTCGGGTCGATCGGTCGTGGCACTTT
GCCTCTGATCGAGCGGCACTTCTCGTTCGATCTCGACCGGATGGTGGTCATCGATCCGGTGGATGATGACCGCAAGCTGC
TCGACGCCCGTGGCATCCGCTACATCCAGTCCGAGGTGACGGCGGAAAACTATCGCGAACTGCTGACGCCGCTGCTGACC
AACGGCGCCGGCCGCGGCTTCTGCGTCAACCTCTCGGTGGATGTCTCCTCCGTGGCGGTGATGGAGCTGTGCCGCGAGAT
CGGCGCGCTCTACGTGGACACGGTGATCGAGCCCTGGAAGGGCTTCTATTTCGATCCCTCCCTCGGCACCGAGGCGCGCA
CCAATTACGCGCTGCGCGAGAGCCTGCTCGCCGCCCGCCGCCGCAATCCCGGCGGCACCACCGCCGTCTCCACCTGCGGC
GCCAATCCGGGCATGGTGTCCTGGTTCGTGAAGCAGGCGCTGCTCAACATCGCCGCCGACACCGGCCTCAGCCTGCCCGA
GCCCAAGACCCGCGAGGAGTGGGCGCGCTTTGCGCAGGCCCTCGGCGTCAAGGGCATCCATGTGGCCGAGCGCGACACGC
AGCGCGCCCGCAATCCCAAGCCCCGCGACGTGTTCGTCAACACCTGGTCGGTGGAAGGCTTCGTCTCCGAGGGCCTGCAG
CCGGCCGAACTCGGCTGGGGCACGCACGAGAAGGAACTGCCCCCGGACGGCCGCACCCACGCCACCGGCTGCGGCGCGGC
GATCTATCTGACGCGCCCCGGCGCGGACACCCGCGTGCGTTCCTGGACGCCCACGCCCGGCCCGCAGTTCGGCTTCCTCG
TGACCCACAACGAGGCGATCTCCATCTCGGACTATTACACGGTCCGCGACGGCGAGAAGGTCGTCTACCGCCCCACCTGC
CACTATGCCTATCATCCGGCCGGTGACGCGGTGCTCTCGCTGCACGAGATGTTCGGCTCCGGCGGCAAGATGCAGAGCGA
CTGGAAGATCCTCGACGAGCACGAGATCGTCGACGGCGTCGACGAACTCGGCGTGCTGATCTATGGCCACGCCAAGAACG
CCTACTGGTTCGGCTCCCAGCTCTCCATCGAGGAGACCCGCCAGCTTGCGCCCTATCAGAACGCCACCGGCCTCCAGGTG
ACCTCCGCTGTGCTCGCGGGCATGGTGTGGGCGCTGGAGAACCCGCAGGCGGGCATCGTGGAAGCGGACGAGATGGACTT
CCGCCGCTGCCTCGAAGTGCAGATGCCGTATCTCGGCCCGGTGATCGGCACCTATACCGACTGGACGCCGCTCCAGAGCC
GCAACACGCTCTTCGCCGGCGATTTCGACGAGGAAGATCCCTGGCAGTTCAAGAACGTCATCGTTCGCTGA

Upstream 100 bases:

>100_bases
GCGCGAGCCATTCCACGGTTGACGCACGGTCCAAGCCTTGGTTGATGGGCGCGCGTCGGTGTGCCCGTCGCCTTCCCCCA
ACCTCCGAGGAGCCCGCGAA

Downstream 100 bases:

>100_bases
GCATCTGATCGCTGATCGCGAAATGAACGCCGCGCCGGACCTCCGGCGCGGCGTTTGTCGTTCTGGGCGGGCGGCACTCT
CGTCGTTCATGGCCAAGTTC

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIRYIQSEVTAENYRELLTPLLT
NGAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWKGFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCG
ANPGMVSWFVKQALLNIAADTGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQ
PAELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAISISDYYTVRDGEKVVYRPTC
HYAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGVDELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQV
TSAVLAGMVWALENPQAGIVEADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR

Sequences:

>Translated_476_residues
MSAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIRYIQSEVTAENYRELLTPLLT
NGAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWKGFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCG
ANPGMVSWFVKQALLNIAADTGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQ
PAELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAISISDYYTVRDGEKVVYRPTC
HYAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGVDELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQV
TSAVLAGMVWALENPQAGIVEADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR
>Mature_475_residues
SAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIRYIQSEVTAENYRELLTPLLTN
GAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWKGFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCGA
NPGMVSWFVKQALLNIAADTGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQP
AELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAISISDYYTVRDGEKVVYRPTCH
YAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGVDELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQVT
SAVLAGMVWALENPQAGIVEADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 52715; Mature: 52584

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIR
CCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHH
YIQSEVTAENYRELLTPLLTNGAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
GFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCGANPGMVSWFVKQALLNIAAD
CEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
TGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQ
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCEEEEEEEEECHHHHCCCC
PAELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAI
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEEECCCEE
SISDYYTVRDGEKVVYRPTCHYAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGV
EEECEEEEECCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCHHHHCCH
DELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQVTSAVLAGMVWALENPQAGIV
HHCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCE
EADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR
ECCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIR
CCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHH
YIQSEVTAENYRELLTPLLTNGAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
GFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCGANPGMVSWFVKQALLNIAAD
CEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
TGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQ
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCEEEEEEEEECHHHHCCCC
PAELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAI
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEEECCCEE
SISDYYTVRDGEKVVYRPTCHYAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGV
EEECEEEEECCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCHHHHCCH
DELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQVTSAVLAGMVWALENPQAGIV
HHCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCE
EADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR
ECCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841401 [H]