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The map label for this gene is gpsA

Identifier: 158421887

GI number: 158421887

Start: 308601

End: 309587

Strand: Direct

Name: gpsA

Synonym: AZC_0263

Alternate gene names: 158421887

Gene position: 308601-309587 (Clockwise)

Preceding gene: 158421886

Following gene: 158421889

Centisome position: 5.75

GC content: 74.16

Gene sequence:

>987_bases
ATGAGTGCGTTCGACCGCATCGGTGTCGTGGGCGCGGGCGCCTGGGGCACCGCGCTCGCCAATGTGGCGGCCCGCGCCGG
CCGCGCCGTGAAGCTGTGGAGCCGCGATCCCGCGCAGGTGGCCGAGATGGCGGCCCGGCGCGAGAATGCGCGCGGCCTGC
CGGGCATTGCGCTGGAGGCGGGCGTCACGCCCACCGCCGATCTGCGCGAGGCGGCCGCCTGTGAAGCCGTGCTGCTGGTG
GTGCCGGCGCAGGTGTGCCGGGCGGTGTCCGGCGAACTGGCGCCGCTGCTTGCGGCGGGCACGCCGCTCGTCTCCTGCGC
CAAGGGCATCGAGCGCGGCACCGCCGCCTTCATGACCGACGTGATCCGCGCCGCCGCTCCCGCCGCCCGGCCCATGGTGC
TCTCCGGCCCAAGCTTCGCGGACGACGTGGCCCGCGGCCTGCCCACGGCCGTGACGCTGGCGGGAGAAGATGGCGCGCTG
GCGGAAACGCTGGCGGCGGCGCTCGGCTCCTCCACCTTCCGGCTCTATCATTCCAGTGACGTGCGTGGGGTGGAGATCGG
CGGCGCGGCGAAAAATGTGCTGGCCATCGCTGCCGGCATCGTCGCCGGCCGCCGGCTCGGTGCCAGCGCGGGTGCGGCGC
TCACGGCGCGGGGCTTCGCGGAGCTTCAACGCTTCGGCCGGGCCTTCGGCGCGCAGCCCGATACGCTCACCGGGCTCTCC
GGTCTCGGAGATCTGATTCTCACGGCGGGTGGACCGCAGTCCCGCAATTTCGCCTTCGGCCTTGCGCTGGGCCAGACGGG
CGAGGTGCCGCAGGGCGGCAAGCTGGCGGAAGGCGCCTTTACGGCGAGCGCGCTGGTGGCCATGGCGGCGGGGCGGGGCG
TCGAGATGCCAATCTGCGCGGCGGTGGATGCGGTGCTCTCGGGGCGCCTCTCGGTGGACGGCGCCATCGAAGCCCTGATG
GCAAGGCCCCAGCGCGCAGAAGCCTGA

Upstream 100 bases:

>100_bases
GGCCTCACCGATCCGCTGGACCTGAGTCCGCGCGCCCGCTGGCCGCTCGATCCCGCGCCCATCACGCCCCGCGCCTGATG
ATGAACCTCCCGAGTGAAGC

Downstream 100 bases:

>100_bases
GGCGGGAGCCCTCCCCGGCGGGGAGGGCCGTGATCTTGAAAGCGTAAGGCGGCGCCCCTCAGAAGCCGACGAAGGTGCTT
TCCAGATGCTGCACTTCCGG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEAGVTPTADLREAAACEAVLLV
VPAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTDVIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGAL
AETLAAALGSSTFRLYHSSDVRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLS
GLGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICAAVDAVLSGRLSVDGAIEALM
ARPQRAEA

Sequences:

>Translated_328_residues
MSAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEAGVTPTADLREAAACEAVLLV
VPAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTDVIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGAL
AETLAAALGSSTFRLYHSSDVRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLS
GLGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICAAVDAVLSGRLSVDGAIEALM
ARPQRAEA
>Mature_327_residues
SAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEAGVTPTADLREAAACEAVLLVV
PAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTDVIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGALA
ETLAAALGSSTFRLYHSSDVRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLSG
LGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICAAVDAVLSGRLSVDGAIEALMA
RPQRAEA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=27.5071633237822, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24307999, Length=354, Percent_Identity=27.683615819209, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=40.4907975460123, Blast_Score=204, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI32564399, Length=352, Percent_Identity=26.4204545454545, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193210136, Length=361, Percent_Identity=26.0387811634349, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564403, Length=361, Percent_Identity=26.0387811634349, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=27.8409090909091, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324513, Length=299, Percent_Identity=28.0936454849498, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320181, Length=279, Percent_Identity=26.8817204301075, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136200, Length=355, Percent_Identity=27.3239436619718, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136202, Length=354, Percent_Identity=27.4011299435028, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136204, Length=352, Percent_Identity=27.5568181818182, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI22026922, Length=345, Percent_Identity=23.4782608695652, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45551945, Length=342, Percent_Identity=25.7309941520468, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=278, Percent_Identity=26.978417266187, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648969, Length=302, Percent_Identity=25.8278145695364, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_AZOC5 (A8IJ80)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523179.1
- ProteinModelPortal:   A8IJ80
- SMR:   A8IJ80
- GeneID:   5688368
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0263
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- BioCyc:   ACAU438753:AZC_0263-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 32591; Mature: 32460

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 108-108 BINDING 108-108 BINDING 140-140 BINDING 255-255 BINDING 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEA
CCCCCCCCEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEC
GVTPTADLREAAACEAVLLVVPAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGALAETLAAALGSSTFRLYHSSD
HHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCC
VRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLS
CCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GLGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICA
HCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
AVDAVLSGRLSVDGAIEALMARPQRAEA
HHHHHHHCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAFDRIGVVGAGAWGTALANVAARAGRAVKLWSRDPAQVAEMAARRENARGLPGIALEA
CCCCCCCEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEC
GVTPTADLREAAACEAVLLVVPAQVCRAVSGELAPLLAAGTPLVSCAKGIERGTAAFMTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VIRAAAPAARPMVLSGPSFADDVARGLPTAVTLAGEDGALAETLAAALGSSTFRLYHSSD
HHHHHCCCCCCEEECCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCC
VRGVEIGGAAKNVLAIAAGIVAGRRLGASAGAALTARGFAELQRFGRAFGAQPDTLTGLS
CCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GLGDLILTAGGPQSRNFAFGLALGQTGEVPQGGKLAEGAFTASALVAMAAGRGVEMPICA
HCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
AVDAVLSGRLSVDGAIEALMARPQRAEA
HHHHHHHCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA