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The map label for this gene is metX [H]

Identifier: 158421853

GI number: 158421853

Start: 271180

End: 272391

Strand: Reverse

Name: metX [H]

Synonym: AZC_0229

Alternate gene names: 158421853

Gene position: 272391-271180 (Counterclockwise)

Preceding gene: 158421857

Following gene: 158421852

Centisome position: 5.07

GC content: 66.5

Gene sequence:

>1212_bases
ATGGGAGAAACGGTCAAAATCGAGACGGGACGCCAGACGGCGGAAGATGTGAAGGCACGCCGGGAAGCGGATGAGCCCCA
TTCGCCGCTCGTGCGCTTCGGAGCCGACAAGCCGCTGCGGCTGGACGCGGGCGTTGAACTGCGCGGGCTCCAGGTCGCCT
ACCAGACCTATGGCGAGCCGAACGCAGACCGCTCCAACGCCATTCTCGTCTGCCACGCCCTTACCGGCGACCAGCACGTG
GCCAACGTCAATCCGGTGACGGGCAAGCCCGGCTGGTGGGAGACCATGGTCGGCCCCGGCAAGCCCATCGATACCGAGCG
CTTCTTCGTGATCTGCGCCAACGTGCTCGGCGGCTGCATGGGCACCACCGGGCCCTCCTCCACCAATCCGGCCACCGGGC
GCGCCTACGGGCTGGAGATGCCCGTGGTGACCATCCGCGACATGGTGAATGCGCAAGCCATGCTGCTCGATCATCTGGGC
ATCGAGCGCCTGTTCTGCGTCGCCGGCGGTTCCATGGGCGGCATGCAGGTGCTGCAATGGGCGGCGAGCTATCCCGAGCG
GGTGTTCTGTGCCCTGCCCATCGCCACCGCCGCGCGTCATTCGGCGCAGAACATCGCCTTTGGCGAGGTCGGCCGGCAGG
CGGTGATGGCTGATCCCGACTGGCGTGGCGGCGACTATCTCAACCAAGGCGTCGCCCCCCATCGCGGGCTCTCGGTGGCG
CGCATGGCCGCGCACATCACCTACATGTCCGACCAGGCGCTGCACCGGAAATTCGGGCGGCGGCTGCAGAACCGCGTCCT
GCCCACTTTCGGCTTCGATGCCGACTTCCAGGTGGAAAGCTATCTGCGCCATCAGGGCGAGAGCTTCGTGCAGCGCTTCG
ACGCCAATTCCTATCTCTACGTCACCCGCGCCATGGATTATTTCGACCTCGCGGCGGATTATGACGGCGTGCTCGCCAAC
GCCTTCCGCAGTTCCAAGACGCGCTTCTGCGTCGTCTCATTCACTTCGGACTGGCTGTTCACGACGCAGGATTCCCGCGC
CATCGTCCATGCCCTCAACGCCTCCGGCGCCAGCGTCTCCTATGCGGAGATCGAGAGCGACAAGGGCCATGACGCCTTCC
TGCTGGAGGAGCCGGAGCTGTTCGACATCTCGCGTGGCTTCCTCGACAGCGCCGCCCGCGCGGCGGGCCTGCCCCCGGCG
AGGACGCGTTAG

Upstream 100 bases:

>100_bases
AGGGGCAGTGACGGTGCGCCGTTAAGGCTGCCGCGCGGACCGCTCCGTTCCGGAGGCGAGGCGGCTTGACAGGGGACCCT
CCGCGTCGCTTGGTGGCGGC

Downstream 100 bases:

>100_bases
ACCATGGCCTATCGGGACCGGACGCTGGATGAGAGCGCGGTGCGCTCGCAGGGCGGGCGCGTCGATCTTGTGGTGGTGGC
CGAGATGGTCGCCCCCGGCT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MGETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEPNADRSNAILVCHALTGDQHV
ANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCMGTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLG
IERLFCVAGGSMGGMQVLQWAASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVA
RMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLYVTRAMDYFDLAADYDGVLAN
AFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVSYAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPA
RTR

Sequences:

>Translated_403_residues
MGETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEPNADRSNAILVCHALTGDQHV
ANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCMGTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLG
IERLFCVAGGSMGGMQVLQWAASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVA
RMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLYVTRAMDYFDLAADYDGVLAN
AFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVSYAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPA
RTR
>Mature_402_residues
GETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEPNADRSNAILVCHALTGDQHVA
NVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCMGTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLGI
ERLFCVAGGSMGGMQVLQWAASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVAR
MAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLYVTRAMDYFDLAADYDGVLANA
FRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVSYAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPAR
TR

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=265, Percent_Identity=38.4905660377359, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 44076; Mature: 43945

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEP
CCCEEEEECCCCCHHHHHHHHCCCCCCCCHHEECCCCCEEECCCCEEEEEEEEEECCCCC
NADRSNAILVCHALTGDQHVANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCM
CCCCCCEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLGIERLFCVAGGSMGGMQVLQW
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHEEEEECCCCCCHHHHHHH
AASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVA
HHCCCCEEEEECCHHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCHHHCCCCCCCCHHHH
RMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
VTRAMDYFDLAADYDGVLANAFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVS
EEECCHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEEEEEECCCCCEEE
YAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPARTR
EEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEP
CCEEEEECCCCCHHHHHHHHCCCCCCCCHHEECCCCCEEECCCCEEEEEEEEEECCCCC
NADRSNAILVCHALTGDQHVANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCM
CCCCCCEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLGIERLFCVAGGSMGGMQVLQW
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHEEEEECCCCCCHHHHHHH
AASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVA
HHCCCCEEEEECCHHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCHHHCCCCCCCCHHHH
RMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
VTRAMDYFDLAADYDGVLANAFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVS
EEECCHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEEEEEECCCCCEEE
YAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPARTR
EEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]