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The map label for this gene is xanP [H]

Identifier: 158421763

GI number: 158421763

Start: 167488

End: 169290

Strand: Reverse

Name: xanP [H]

Synonym: AZC_0139

Alternate gene names: 158421763

Gene position: 169290-167488 (Counterclockwise)

Preceding gene: 158421764

Following gene: 158421760

Centisome position: 3.15

GC content: 69.33

Gene sequence:

>1803_bases
ATGACGCCTGTTCCGGGCGCCTCGCCAGCCAAGCGACCGCAGGGGCTCCTCAACCGTCTCCGCCGCCTCGTGATGCTGGA
ACACGGCACGCCCCACCGGCCGCGCCGCCGGCCGCCGGCGCTGGTGTTCGGGCTCGAGGACAAGGTTCCCGCCGGGGCGC
TTATCGCCCTCTCGGGCCAGCACGCCATGCTGGCGCTCACCTTCCTGATCTATCCGCTGGTGGCGGCCAGCCAGGTCGGG
CTATCGCAGCCCGAGACCAATGCAGTGCTCACCGCCTGCACGCTGTGCATCGGCATCGCCACCATGCTCCAGTGCGCGCG
CTCCCGGGTCGGCAGCGGCTATCTCATCGTCCATGTGCCCTCGCCCGGCGCCTTGCCGCTGGCCATCCAGGCGCTGACCC
TGGGCGGCGTCGGGCTCATGGCGGCCATGACGCTGCTGGTGGGCGTGTCGCAACTGTTCATCGCCCGCATCGTTCGCCCG
CTTCGGGTGCTGCTGCCGCCGGAGGTCTGCGGCGTCGCGGTGACCACGCTCGGCATCTCGCTGGCGGAACCGGCGCTCCG
GCGCGCGCTCGGGCTCGACCGGGGCAGCAGCGTGGTGGACGACAATGCGCTGATCGTCAGCCTCGTGACCGTGGCGCTCA
TCGTCGGCATCGCCATTTTCACGCCCCGGCGCATCAAGATCTTCGCCGTCCTGATAGGGGCCTCCTCGGGCTGGGCGCTC
GCCGCCTGGCTCGGCATCGAGCAGCCGGGCGGCGCGGCGCTGCTCGCCTCGGCGCCGCTCGTGGCACTGCCTTCGCTGCA
TCTGCCCGCCTTCGAGATCGCCCCTTCCCTGCTGCCGCTGGCGGCACTGAGCGTGATGCTGAACATCGTGGACGTGCTCA
GCATCACCGTCTCGCTGGAAAAGATGAACGATGCGGAATGGCGGCGGGCGGACATGCGGGCGGCGAGCCGCGCCGTCACC
ACATCCGGCATCGGCAACGTGCTGAACGGCCTCGTCTCCGGCTTCCAGTCGGGCCTGTCATCCTCGGCAGTGGGCCTTGC
CTTCGCCACGGGGGCCACCGCGCGCATCATCGGCTTCGTCGCCGGCGCGCTCATCTTCGCCACCGCCTTCTTCCCGAAGG
CCATCGTGGCGCTCACCCTCATTCCCGCGCCCGTGGTGGGTGGCATCCTCATCTACACCACCGCTTACCTGCTGGTGGCG
GGCATGGAGCTGATCCTTTCCCGCCGTCTCAGCGAGCGGCGGGTGTTTCTCGTCGGCTTGTCGATCCTCGCGGCTCTGTC
CGTCGCGCTGCTGCCCATCAAGGGGCAGTTTCCGGGCTGGATCCAGCCTCTGGTCTCCACCCCCATGAGCGTCGGCGCCT
TCTGCGCCATCGTGCTCAACCTCATCTTCCGGATCGGCATCTCGCAGGAGTCCGGCTTTACCGCCGGTCTCGGCACCGAT
CCCTACCCGACCATGCGCGACTTCCTCGAGCGCCAAGGGGATCTCTGGGGTGCGCGGCGCGACGTGATCGCCGCCGCCAT
TCCGGTGGGCGCCCAGGCGCTGGAGCTGCTTCTGGAGAACAGCATCGCCACCGGCGAGGTGGAGGTGCGCGCCCGCTTCG
ACGAGACGCACCTCGACGTTTTCCTGCTTTATGACGGCGCGGTGCTGGAGCCGCCAAAGGCGCGCCCCTCGCCCGAGGCC
CTTCTGGGTGATGACGCGGAGGTGGCGGCCTTCTGCGCCTATATGATCCAGAAGCTCTCCGACCACGTCACTTTCGGCCA
GAGCAGCGGGCGGGCCCGCATTGCGCTCCGCTTTGACCACTGA

Upstream 100 bases:

>100_bases
CCGCCCGTGGCCATCGCCCACCATCTCATCCGCGCCTTCGTGGAAGGCGCCACCGCCTGATCGGTGCGGATCAGAGCCGG
CCAGTGAGGGAGCCTGTCGC

Downstream 100 bases:

>100_bases
GGGCCGCAGCGCGCCTCACGCCTCCGGCTTGGGCGAGCGGGTGGTGCGGAAGGGGTGGGCGGGATAGACGCCCAGAATGC
GCATCTCGCGGGAGAAGAAG

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MTPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQHAMLALTFLIYPLVAASQVG
LSQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVPSPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRP
LRVLLPPEVCGVAVTTLGISLAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWAL
AAWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLEKMNDAEWRRADMRAASRAVT
TSGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFVAGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVA
GMELILSRRLSERRVFLVGLSILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTD
PYPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDVFLLYDGAVLEPPKARPSPEA
LLGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH

Sequences:

>Translated_600_residues
MTPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQHAMLALTFLIYPLVAASQVG
LSQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVPSPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRP
LRVLLPPEVCGVAVTTLGISLAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWAL
AAWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLEKMNDAEWRRADMRAASRAVT
TSGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFVAGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVA
GMELILSRRLSERRVFLVGLSILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTD
PYPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDVFLLYDGAVLEPPKARPSPEA
LLGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH
>Mature_599_residues
TPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQHAMLALTFLIYPLVAASQVGL
SQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVPSPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRPL
RVLLPPEVCGVAVTTLGISLAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWALA
AWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLEKMNDAEWRRADMRAASRAVTT
SGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFVAGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVAG
MELILSRRLSERRVFLVGLSILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTDP
YPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDVFLLYDGAVLEPPKARPSPEAL
LGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790087, Length=441, Percent_Identity=24.7165532879819, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082181, Length=430, Percent_Identity=24.4186046511628, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 62923; Mature: 62792

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQ
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCC
HAMLALTFLIYPLVAASQVGLSQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
SPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRPLRVLLPPEVCGVAVTTLGIS
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWAL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEE
AAWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLE
EEEECCCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMNDAEWRRADMRAASRAVTTSGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHHHHH
AGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVAGMELILSRRLSERRVFLVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHH
SILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTD
HHHHHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDV
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
FLLYDGAVLEPPKARPSPEALLGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH
EEEECCCEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQ
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCC
HAMLALTFLIYPLVAASQVGLSQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
SPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRPLRVLLPPEVCGVAVTTLGIS
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWAL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEE
AAWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLE
EEEECCCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMNDAEWRRADMRAASRAVTTSGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCHHHHHHHH
AGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVAGMELILSRRLSERRVFLVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHH
SILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTD
HHHHHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDV
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
FLLYDGAVLEPPKARPSPEALLGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH
EEEECCCEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]