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The map label for this gene is yeiG [C]

Identifier: 158339020

GI number: 158339020

Start: 6005622

End: 6006467

Strand: Reverse

Name: yeiG [C]

Synonym: AM1_5939

Alternate gene names: 158339020

Gene position: 6006467-6005622 (Counterclockwise)

Preceding gene: 158339023

Following gene: 158339019

Centisome position: 92.35

GC content: 52.13

Gene sequence:

>846_bases
ATGTCAGTATCGTTCACCTGTCGTCAGGAGACTGTCTGTTTTGGCGGCACCATGGGATTCTACAGCCATGACTCCCAAAC
CTGCCAAACTCCCATGAACTTTGCCGTCTATCAGCCCCCCCAGGCGAAGACAGGTCCAGTGCCCGTGCTCTACTTTTTAT
CGGGACTCACCTGTACAGAAGAGAATTTTGTCACCAAGGCGGGTGCCCAGCGATATGCGGCTGAATATGGTGTGATGCTA
GTGGCACCGGATACCAGTCCACGAGATGGCGAAACCCCAGGTGCAGAAGAAGATTGGGATATAGGGACCGGGGCGGGGTT
TTATGTGAATGCAACGGCGGAACCTTGGGCCAAGCATTATCACATGTATGACTATGTTGTCGAAGAGTTACCAGCACTAA
TTGCCCAGTTCTTTCCGGCCAATGAGCGGCAGAGCGTGTGTGGTCATTCCATGGGCGGCCATGGGGCCTTAGTCTGTGGG
TTACGGAATCGCGATCGCTATCGGTCCATTTCCGCCTTTGCCCCCATCGTGGCTCCGACCCGCTGCCCTTGGGGCCATAA
AATCTTCTCCAATTATTTGGGCGTGGATATGGAAACTTGGAAGCAATACGATGCCTGTGAGTTGGTACATCATTACCAAG
ATGACCGCCCTCTGTTAGTGGATCAAGGCTCAGCGGACTCTTTTCTTGAAGAACAATTGCGGCCTCATCTCTTACAGGAA
GCCTGTGAACAAGCCCAGCGCCCCTTAACCCTGAGAATGCAGCCAGGCTATGACCATAGCTACTATTTCATCGCCAGTTT
TATCGGAGATCACATCAAATTCCATGCCGAATATCTGTGTTCGTGA

Upstream 100 bases:

>100_bases
GCGAATTTGCGATTCGTAAATTGAGGTAAACAATCTGGTGATTCGGGATGCGATCGCATCTCCATCCTCCATAATGGCGA
AGTTGCTCTAGATTGCATCT

Downstream 100 bases:

>100_bases
GGGTTTCCTCAACTGAAATTCGATACCAGGGGGAACAATGTCCTAAAATTAGGGGATTGCCCACCCTCACAGTTTCATGG
ACATCCAGGCATTTATTCAA

Product: esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSVSFTCRQETVCFGGTMGFYSHDSQTCQTPMNFAVYQPPQAKTGPVPVLYFLSGLTCTEENFVTKAGAQRYAAEYGVML
VAPDTSPRDGETPGAEEDWDIGTGAGFYVNATAEPWAKHYHMYDYVVEELPALIAQFFPANERQSVCGHSMGGHGALVCG
LRNRDRYRSISAFAPIVAPTRCPWGHKIFSNYLGVDMETWKQYDACELVHHYQDDRPLLVDQGSADSFLEEQLRPHLLQE
ACEQAQRPLTLRMQPGYDHSYYFIASFIGDHIKFHAEYLCS

Sequences:

>Translated_281_residues
MSVSFTCRQETVCFGGTMGFYSHDSQTCQTPMNFAVYQPPQAKTGPVPVLYFLSGLTCTEENFVTKAGAQRYAAEYGVML
VAPDTSPRDGETPGAEEDWDIGTGAGFYVNATAEPWAKHYHMYDYVVEELPALIAQFFPANERQSVCGHSMGGHGALVCG
LRNRDRYRSISAFAPIVAPTRCPWGHKIFSNYLGVDMETWKQYDACELVHHYQDDRPLLVDQGSADSFLEEQLRPHLLQE
ACEQAQRPLTLRMQPGYDHSYYFIASFIGDHIKFHAEYLCS
>Mature_280_residues
SVSFTCRQETVCFGGTMGFYSHDSQTCQTPMNFAVYQPPQAKTGPVPVLYFLSGLTCTEENFVTKAGAQRYAAEYGVMLV
APDTSPRDGETPGAEEDWDIGTGAGFYVNATAEPWAKHYHMYDYVVEELPALIAQFFPANERQSVCGHSMGGHGALVCGL
RNRDRYRSISAFAPIVAPTRCPWGHKIFSNYLGVDMETWKQYDACELVHHYQDDRPLLVDQGSADSFLEEQLRPHLLQEA
CEQAQRPLTLRMQPGYDHSYYFIASFIGDHIKFHAEYLCS

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=270, Percent_Identity=54.8148148148148, Blast_Score=313, Evalue=1e-85,
Organism=Escherichia coli, GI1788477, Length=273, Percent_Identity=56.043956043956, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI1786551, Length=271, Percent_Identity=50.1845018450184, Blast_Score=294, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17510185, Length=278, Percent_Identity=48.5611510791367, Blast_Score=260, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6322393, Length=296, Percent_Identity=42.2297297297297, Blast_Score=226, Evalue=3e-60,
Organism=Drosophila melanogaster, GI45551932, Length=288, Percent_Identity=46.5277777777778, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24648347, Length=274, Percent_Identity=47.8102189781022, Blast_Score=263, Evalue=7e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31588; Mature: 31456

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSFTCRQETVCFGGTMGFYSHDSQTCQTPMNFAVYQPPQAKTGPVPVLYFLSGLTCTE
CCCEEEECCCEEEECCCCCCCCCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCC
ENFVTKAGAQRYAAEYGVMLVAPDTSPRDGETPGAEEDWDIGTGAGFYVNATAEPWAKHY
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
HMYDYVVEELPALIAQFFPANERQSVCGHSMGGHGALVCGLRNRDRYRSISAFAPIVAPT
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCC
RCPWGHKIFSNYLGVDMETWKQYDACELVHHYQDDRPLLVDQGSADSFLEEQLRPHLLQE
CCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHH
ACEQAQRPLTLRMQPGYDHSYYFIASFIGDHIKFHAEYLCS
HHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVSFTCRQETVCFGGTMGFYSHDSQTCQTPMNFAVYQPPQAKTGPVPVLYFLSGLTCTE
CCEEEECCCEEEECCCCCCCCCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCC
ENFVTKAGAQRYAAEYGVMLVAPDTSPRDGETPGAEEDWDIGTGAGFYVNATAEPWAKHY
CHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
HMYDYVVEELPALIAQFFPANERQSVCGHSMGGHGALVCGLRNRDRYRSISAFAPIVAPT
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCC
RCPWGHKIFSNYLGVDMETWKQYDACELVHHYQDDRPLLVDQGSADSFLEEQLRPHLLQE
CCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHH
ACEQAQRPLTLRMQPGYDHSYYFIASFIGDHIKFHAEYLCS
HHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]