Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 158339008

GI number: 158339008

Start: 5994015

End: 5996021

Strand: Direct

Name: htpG [H]

Synonym: AM1_5927

Alternate gene names: 158339008

Gene position: 5994015-5996021 (Clockwise)

Preceding gene: 158339006

Following gene: 158339010

Centisome position: 92.16

GC content: 46.14

Gene sequence:

>2007_bases
ATGACTATGCTGGAACAAGGCACAATTTCGATACATACCGAGAATATCTTCCCGATCATCAAAAAATGGCTCTATTCAGA
CCATGAGATTTTCTTGCGGGAACTGATTTCCAATGCAGTGGACGCCATGCAGAAAATGAAGATGGTGTCGATGGCAGGGG
AATATTCCGGTGAAGTGGGGGAACCTGAGGTTGTAATCACCGTTGACAAGGATAACAAGCAGCTCACCATTACCGACAAT
GGCATCGGCATGACAGCTGATGAGGTCAAGCAATATATTACTCAGGTGGCCTTTTCCAGTGCAGAGGAATTTGTCGAGAA
ATATAAAGACAGTGGTGATCAGGCCATTATTGGCCATTTTGGCTTGGGCTTTTATTCGTCCTTTATGGTGGCGCAAAAAG
TTGAAATCGATACTCTGTCTTATAAAGAAGGGGCTGAAGCCGTTCATTGGTCCTGCGAAGGCAATACGGACTATCAGTTA
GAGGCCTCAGAGTGGAATCAGCGAGGGACTAAGATTACCCTCACTTTGATGGAAGAGGAGATTGAATATGCCGAAGAGGC
TCGCATCAAGTCTTTGGTAAAGACCTACTGTGATTTCCTGCCTGTCCCCATCAAATTAGGGGATGAGCAAATTAACAAGC
AAAAAGCACCTTGGAAAGAGTCTCCTAGCAATCTTACCGATGAAGACTATCTGGAGTTTTATCGGTATCTATATCCCTTC
CAGGAAGATCCTTTACTCTGGGTACATCTAAATACGGACTATCCGTTTATCGTCAATGGCATTCTCTACTTTCCGAAGCT
GAAGCCAGATATTGATGTGACAAAAGGCCAAATAAAGCTGTTTTGCAATCAGGTATTTGTTAGCGACAATTGTGAAGAGG
TGATTCCTCAGTTCCTGATGCCGCTCCAGGGCGTGATTGACAGTAGCGATATCCCTCTTAATGTCTCCCGTAGCTTTTTG
CAGAATGATCGCACGGTCCGCCGGATTGCGGATTATATTGCTAAGAAAGTGGGGGATCGCCTGAAAGCCCTCTATCGTGA
TGACCGGGATGCCTATATTCGCTGCTGGCAAGATGTGGGGACTTTCGTCAAATTCGGCTCCATCAATAACGATAAGTTCA
AGAAACAAATCGAAGATATTTTGATTTATCGAACCACTGCTGAACTTGCTCCAGCCCCAGAGCCTACGGCTGAACCTGCC
ATTGAAAATTCTGAAGATACAACGGATGATGCTTGGGCAGATTCTCCAACTGATGCCAAAGAAGAGGCTTCTGCTGCCTC
CTCTGAACCGCCCCATACGACGTTGAAAGAGTATCTGGAGCGCAATCAGGAGCGGCATGAGAACCAGGTTTACTACTGTA
CCGATGAGGTCAACCAAGCGACCTATGTCTCCTTACTGAAAAATCAAGGATTGGAAGTACTGTTCCTGGATACTTTTATT
GACACCCACTTTGTCCCGTTCCTAGAACGAGAATATACAGACGTGAAGTTTGCACGGGTGGATGCGGATTTGGATGAAAC
CCTTATTGATAAGGATCAAGCAGCCGAAATTGTCGATCCCACTACCAATCAAACGCGCAGTGAAATTATCAAGGCCCTGT
TTGAGAAATCTCTGGACAATTCTAATCTAACCATCCGCACCGAAGCGTTGAAGTCGGATACTCCTCAAGGGGCACCTCCG
GCAATGGTGCTGTTACCGGAATCCGCTCGTCGGATGCAGGAGATGATGGCCATGATGCAGCAACAGAATATGCAGTTTCC
TACTGAATATACGTTGCTAGTCAATACCTCTCATCCACTGATTCAAAATCTGTTGACTCTGAGTCAGGGAGGAGTGGTCC
AAGCGGATGGTCAATCTCCTGCAGGAGAATTAGCAAATCAAATTTGCCACCATGTCTATGATTTGGCTCTGATGGCTCAG
AAAGGGTTTGATGCTGAGGGAATGCAAGCATTTACCGAGCGCTCTAACCAGGTGCTCACTCGGTTGACTGAGTTAGCTGC
GAAATAG

Upstream 100 bases:

>100_bases
CGGTGATCTCACCTGCACTTACAGTATCTAAATGGCTGTTGAAAATGCGATATTTTAAGGGAAATGATGGAATTACTATT
GATCGCCTGAACGGATACCA

Downstream 100 bases:

>100_bases
AGACCTTAAAACTTGGGGAAGCGCCCCTAAGCTTCAATATTTATAGCCCGCTTAGTATCATTGCTGAGCGGGCTAAGTGA
TGGGGCAGATCAGGCGGAAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MTMLEQGTISIHTENIFPIIKKWLYSDHEIFLRELISNAVDAMQKMKMVSMAGEYSGEVGEPEVVITVDKDNKQLTITDN
GIGMTADEVKQYITQVAFSSAEEFVEKYKDSGDQAIIGHFGLGFYSSFMVAQKVEIDTLSYKEGAEAVHWSCEGNTDYQL
EASEWNQRGTKITLTLMEEEIEYAEEARIKSLVKTYCDFLPVPIKLGDEQINKQKAPWKESPSNLTDEDYLEFYRYLYPF
QEDPLLWVHLNTDYPFIVNGILYFPKLKPDIDVTKGQIKLFCNQVFVSDNCEEVIPQFLMPLQGVIDSSDIPLNVSRSFL
QNDRTVRRIADYIAKKVGDRLKALYRDDRDAYIRCWQDVGTFVKFGSINNDKFKKQIEDILIYRTTAELAPAPEPTAEPA
IENSEDTTDDAWADSPTDAKEEASAASSEPPHTTLKEYLERNQERHENQVYYCTDEVNQATYVSLLKNQGLEVLFLDTFI
DTHFVPFLEREYTDVKFARVDADLDETLIDKDQAAEIVDPTTNQTRSEIIKALFEKSLDNSNLTIRTEALKSDTPQGAPP
AMVLLPESARRMQEMMAMMQQQNMQFPTEYTLLVNTSHPLIQNLLTLSQGGVVQADGQSPAGELANQICHHVYDLALMAQ
KGFDAEGMQAFTERSNQVLTRLTELAAK

Sequences:

>Translated_668_residues
MTMLEQGTISIHTENIFPIIKKWLYSDHEIFLRELISNAVDAMQKMKMVSMAGEYSGEVGEPEVVITVDKDNKQLTITDN
GIGMTADEVKQYITQVAFSSAEEFVEKYKDSGDQAIIGHFGLGFYSSFMVAQKVEIDTLSYKEGAEAVHWSCEGNTDYQL
EASEWNQRGTKITLTLMEEEIEYAEEARIKSLVKTYCDFLPVPIKLGDEQINKQKAPWKESPSNLTDEDYLEFYRYLYPF
QEDPLLWVHLNTDYPFIVNGILYFPKLKPDIDVTKGQIKLFCNQVFVSDNCEEVIPQFLMPLQGVIDSSDIPLNVSRSFL
QNDRTVRRIADYIAKKVGDRLKALYRDDRDAYIRCWQDVGTFVKFGSINNDKFKKQIEDILIYRTTAELAPAPEPTAEPA
IENSEDTTDDAWADSPTDAKEEASAASSEPPHTTLKEYLERNQERHENQVYYCTDEVNQATYVSLLKNQGLEVLFLDTFI
DTHFVPFLEREYTDVKFARVDADLDETLIDKDQAAEIVDPTTNQTRSEIIKALFEKSLDNSNLTIRTEALKSDTPQGAPP
AMVLLPESARRMQEMMAMMQQQNMQFPTEYTLLVNTSHPLIQNLLTLSQGGVVQADGQSPAGELANQICHHVYDLALMAQ
KGFDAEGMQAFTERSNQVLTRLTELAAK
>Mature_667_residues
TMLEQGTISIHTENIFPIIKKWLYSDHEIFLRELISNAVDAMQKMKMVSMAGEYSGEVGEPEVVITVDKDNKQLTITDNG
IGMTADEVKQYITQVAFSSAEEFVEKYKDSGDQAIIGHFGLGFYSSFMVAQKVEIDTLSYKEGAEAVHWSCEGNTDYQLE
ASEWNQRGTKITLTLMEEEIEYAEEARIKSLVKTYCDFLPVPIKLGDEQINKQKAPWKESPSNLTDEDYLEFYRYLYPFQ
EDPLLWVHLNTDYPFIVNGILYFPKLKPDIDVTKGQIKLFCNQVFVSDNCEEVIPQFLMPLQGVIDSSDIPLNVSRSFLQ
NDRTVRRIADYIAKKVGDRLKALYRDDRDAYIRCWQDVGTFVKFGSINNDKFKKQIEDILIYRTTAELAPAPEPTAEPAI
ENSEDTTDDAWADSPTDAKEEASAASSEPPHTTLKEYLERNQERHENQVYYCTDEVNQATYVSLLKNQGLEVLFLDTFID
THFVPFLEREYTDVKFARVDADLDETLIDKDQAAEIVDPTTNQTRSEIIKALFEKSLDNSNLTIRTEALKSDTPQGAPPA
MVLLPESARRMQEMMAMMQQQNMQFPTEYTLLVNTSHPLIQNLLTLSQGGVVQADGQSPAGELANQICHHVYDLALMAQK
GFDAEGMQAFTERSNQVLTRLTELAAK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=691, Percent_Identity=27.0622286541245, Blast_Score=240, Evalue=4e-63,
Organism=Homo sapiens, GI4507677, Length=672, Percent_Identity=26.0416666666667, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI153792590, Length=192, Percent_Identity=36.9791666666667, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI154146191, Length=192, Percent_Identity=36.9791666666667, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI20149594, Length=192, Percent_Identity=36.4583333333333, Blast_Score=119, Evalue=1e-26,
Organism=Escherichia coli, GI1786679, Length=669, Percent_Identity=30.4932735426009, Blast_Score=261, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17559162, Length=546, Percent_Identity=28.7545787545788, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI115535205, Length=483, Percent_Identity=28.7784679089027, Blast_Score=212, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI115535167, Length=393, Percent_Identity=30.5343511450382, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17542208, Length=717, Percent_Identity=26.3598326359833, Blast_Score=197, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323840, Length=535, Percent_Identity=27.4766355140187, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6325016, Length=196, Percent_Identity=36.734693877551, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24586016, Length=391, Percent_Identity=35.5498721227622, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=25.5162241887906, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17647529, Length=407, Percent_Identity=23.8329238329238, Blast_Score=120, Evalue=4e-27,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 75955; Mature: 75824

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLEQGTISIHTENIFPIIKKWLYSDHEIFLRELISNAVDAMQKMKMVSMAGEYSGEVG
CCCCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPEVVITVDKDNKQLTITDNGIGMTADEVKQYITQVAFSSAEEFVEKYKDSGDQAIIGHF
CCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
GLGFYSSFMVAQKVEIDTLSYKEGAEAVHWSCEGNTDYQLEASEWNQRGTKITLTLMEEE
HHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCCEEEEHHHHCCCCCEEEEEEEHHH
IEYAEEARIKSLVKTYCDFLPVPIKLGDEQINKQKAPWKESPSNLTDEDYLEFYRYLYPF
HHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QEDPLLWVHLNTDYPFIVNGILYFPKLKPDIDVTKGQIKLFCNQVFVSDNCEEVIPQFLM
CCCCEEEEEECCCCCCHHHHHEECCCCCCCCCCCCCHHHEEEHHHHCCCCHHHHHHHHHH
PLQGVIDSSDIPLNVSRSFLQNDRTVRRIADYIAKKVGDRLKALYRDDRDAYIRCWQDVG
HHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TFVKFGSINNDKFKKQIEDILIYRTTAELAPAPEPTAEPAIENSEDTTDDAWADSPTDAK
HHEEECCCCCHHHHHHHHHHHEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EEASAASSEPPHTTLKEYLERNQERHENQVYYCTDEVNQATYVSLLKNQGLEVLFLDTFI
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEHHH
DTHFVPFLEREYTDVKFARVDADLDETLIDKDQAAEIVDPTTNQTRSEIIKALFEKSLDN
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SNLTIRTEALKSDTPQGAPPAMVLLPESARRMQEMMAMMQQQNMQFPTEYTLLVNTSHPL
CCEEEEEHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHH
IQNLLTLSQGGVVQADGQSPAGELANQICHHVYDLALMAQKGFDAEGMQAFTERSNQVLT
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RLTELAAK
HHHHHHCC
>Mature Secondary Structure 
TMLEQGTISIHTENIFPIIKKWLYSDHEIFLRELISNAVDAMQKMKMVSMAGEYSGEVG
CCCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EPEVVITVDKDNKQLTITDNGIGMTADEVKQYITQVAFSSAEEFVEKYKDSGDQAIIGHF
CCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
GLGFYSSFMVAQKVEIDTLSYKEGAEAVHWSCEGNTDYQLEASEWNQRGTKITLTLMEEE
HHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCCEEEEHHHHCCCCCEEEEEEEHHH
IEYAEEARIKSLVKTYCDFLPVPIKLGDEQINKQKAPWKESPSNLTDEDYLEFYRYLYPF
HHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QEDPLLWVHLNTDYPFIVNGILYFPKLKPDIDVTKGQIKLFCNQVFVSDNCEEVIPQFLM
CCCCEEEEEECCCCCCHHHHHEECCCCCCCCCCCCCHHHEEEHHHHCCCCHHHHHHHHHH
PLQGVIDSSDIPLNVSRSFLQNDRTVRRIADYIAKKVGDRLKALYRDDRDAYIRCWQDVG
HHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TFVKFGSINNDKFKKQIEDILIYRTTAELAPAPEPTAEPAIENSEDTTDDAWADSPTDAK
HHEEECCCCCHHHHHHHHHHHEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EEASAASSEPPHTTLKEYLERNQERHENQVYYCTDEVNQATYVSLLKNQGLEVLFLDTFI
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEHHH
DTHFVPFLEREYTDVKFARVDADLDETLIDKDQAAEIVDPTTNQTRSEIIKALFEKSLDN
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SNLTIRTEALKSDTPQGAPPAMVLLPESARRMQEMMAMMQQQNMQFPTEYTLLVNTSHPL
CCEEEEEHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHH
IQNLLTLSQGGVVQADGQSPAGELANQICHHVYDLALMAQKGFDAEGMQAFTERSNQVLT
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RLTELAAK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]