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The map label for this gene is pkn1 [H]

Identifier: 158338748

GI number: 158338748

Start: 5723712

End: 5724434

Strand: Reverse

Name: pkn1 [H]

Synonym: AM1_5659

Alternate gene names: 158338748

Gene position: 5724434-5723712 (Counterclockwise)

Preceding gene: 158338749

Following gene: 158338747

Centisome position: 88.02

GC content: 48.13

Gene sequence:

>723_bases
TTGCAGCAATATATTGAACATCTTGATCAACAACCCTTTATTTATATGGTTGAGATACCAGGAGGGGAATTTATCATGGG
CGCATCTGAAGCAGAGGAAGGAAGTTGGGATCGGGAACGGCCTCAACATCATGTGATCATCGCCCCATTTTTGATGAGTC
AGTTTACTGTGACTCAAGCCCAGTGGGAAGCCATCATGGAGTCAAACCCTTCTCAATTCAAAGGAGCGAATCGGCCCGTC
GAAAATATTACTTGGAATGAGGCAGTGGGCTTTTGCCAAAAACTGTCCCAGAAAAGTGGCAAGGACTACCGCCTTCCGAG
TGAAGCAGAGTGGGAATATGCCTGCCGAGGCGGAACGTCAACTCCCTTTCATTATGGAGAGACGATTACCCCCGCCCTTG
CCAACTATAACGACGCTAACTATGGCTCCGAGGGAAAGAATCAGCAACAGACAACAGAGGTCGGTTGCTTTCCTCCCAAT
GGATTTGGTTTATACGACATGCATGGAAATGTTTGGGAATTATGCCTTGATACCTGGCATGGGAACTATAAAGGTGCGCC
AACGGATGGGAATGCTTGGAGTGATCATAATCCTAAATATCATGTAGCTCGTGGCGGTTCCTACATCAGCGGTCCGAGGC
TCTGTCGCTGTGCGAATCGTGGTCGCAGTCCTATTGCTGGTTTAATTCAGGGGTTTCGGATTGTCTCAGGACTAACGCAT
TGA

Upstream 100 bases:

>100_bases
TAGTATAGCTAGCCTGGAGATCAACTTCATCTCTTTCAAGCATCAACACAAATCGGAATACACTGGGGGCTAAATCGGCT
TTTCTACCCAATGAACCGCC

Downstream 100 bases:

>100_bases
CATGGACTTTATTGTGTGAGTTGTAGAGATAAAGGCTGTTAACGTTCTACCTCTCTTGCGAATACCCAGTAAGCCTTCAA
CAGCTCATTGCACCCAAGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQQYIEHLDQQPFIYMVEIPGGEFIMGASEAEEGSWDRERPQHHVIIAPFLMSQFTVTQAQWEAIMESNPSQFKGANRPV
ENITWNEAVGFCQKLSQKSGKDYRLPSEAEWEYACRGGTSTPFHYGETITPALANYNDANYGSEGKNQQQTTEVGCFPPN
GFGLYDMHGNVWELCLDTWHGNYKGAPTDGNAWSDHNPKYHVARGGSYISGPRLCRCANRGRSPIAGLIQGFRIVSGLTH

Sequences:

>Translated_240_residues
MQQYIEHLDQQPFIYMVEIPGGEFIMGASEAEEGSWDRERPQHHVIIAPFLMSQFTVTQAQWEAIMESNPSQFKGANRPV
ENITWNEAVGFCQKLSQKSGKDYRLPSEAEWEYACRGGTSTPFHYGETITPALANYNDANYGSEGKNQQQTTEVGCFPPN
GFGLYDMHGNVWELCLDTWHGNYKGAPTDGNAWSDHNPKYHVARGGSYISGPRLCRCANRGRSPIAGLIQGFRIVSGLTH
>Mature_240_residues
MQQYIEHLDQQPFIYMVEIPGGEFIMGASEAEEGSWDRERPQHHVIIAPFLMSQFTVTQAQWEAIMESNPSQFKGANRPV
ENITWNEAVGFCQKLSQKSGKDYRLPSEAEWEYACRGGTSTPFHYGETITPALANYNDANYGSEGKNQQQTTEVGCFPPN
GFGLYDMHGNVWELCLDTWHGNYKGAPTDGNAWSDHNPKYHVARGGSYISGPRLCRCANRGRSPIAGLIQGFRIVSGLTH

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=255, Percent_Identity=32.156862745098, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI38202250, Length=280, Percent_Identity=30, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI257470977, Length=225, Percent_Identity=30.2222222222222, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20130397, Length=157, Percent_Identity=36.3057324840764, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 26884; Mature: 26884

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQYIEHLDQQPFIYMVEIPGGEFIMGASEAEEGSWDRERPQHHVIIAPFLMSQFTVTQA
CCHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
QWEAIMESNPSQFKGANRPVENITWNEAVGFCQKLSQKSGKDYRLPSEAEWEYACRGGTS
HHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
TPFHYGETITPALANYNDANYGSEGKNQQQTTEVGCFPPNGFGLYDMHGNVWELCLDTWH
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHHC
GNYKGAPTDGNAWSDHNPKYHVARGGSYISGPRLCRCANRGRSPIAGLIQGFRIVSGLTH
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQYIEHLDQQPFIYMVEIPGGEFIMGASEAEEGSWDRERPQHHVIIAPFLMSQFTVTQA
CCHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
QWEAIMESNPSQFKGANRPVENITWNEAVGFCQKLSQKSGKDYRLPSEAEWEYACRGGTS
HHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
TPFHYGETITPALANYNDANYGSEGKNQQQTTEVGCFPPNGFGLYDMHGNVWELCLDTWH
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHHC
GNYKGAPTDGNAWSDHNPKYHVARGGSYISGPRLCRCANRGRSPIAGLIQGFRIVSGLTH
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]