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The map label for this gene is ubiB [C]

Identifier: 158338699

GI number: 158338699

Start: 5670477

End: 5672207

Strand: Reverse

Name: ubiB [C]

Synonym: AM1_5607

Alternate gene names: 158338699

Gene position: 5672207-5670477 (Counterclockwise)

Preceding gene: 158338700

Following gene: 158338698

Centisome position: 87.21

GC content: 47.08

Gene sequence:

>1731_bases
GTGCCTGTGTCAGTTTCATCCTCTGAGTTGACCTTCCCAAAACAAAATCGCAAAGCCTATCGCTGGAATCGAGAAAGCTA
TTCTCGGCAACGTCGTTTCCTGGATATTTGGGCCTTTGTGCTGCAGCTGCTTAGCTCTAGGTGGTGGTTGAGTAAGTCTT
GGAGTTATGCCGGAGGGATGACGGAAGACAAGCGAGCGACCCGACGACGCAAGCAAGCCGTCTGGATCCGAGAGACCTTA
CTCGATCTAGGACCCACCTTTATTAAAGTTGGACAATTGTTCTCAACCCGTGCGGATTTATTCCCAGCGGAGTATGTCGA
AGAGCTGTCCAAGCTCCAGGATCGTGTGCCTGCCTTTAGCTATGAGATTGTAGAACGAATTATTGAGAAGGACTTTGGCC
GCACTATTCCAGAGTTATTTTGCAGTTTTGATCCCGTTCCTCTAGCTGCGGCGAGCTTAGGTCAAGTTCACCGTGCTCAA
CTGCAGTCTGGGGAAGAAGTTGTTGTCAAAATTCAGCGTCCGGGTCTCAAAAAGCTGTTTGATATTGACTTGAGAATTTT
AAAAGGCATTGCCCATTATTTTCAAAACCACCCCAAGTGGGGGCCTGGGAGAGACTGGCTGGGCATCTACGAAGAATGCT
GCAAAATCCTCTATGAAGAAATTGACTATTTAAATGAAGGCCGCAATGCCGATCAGTTTCGGCGCAATTTCCGGGAACAA
GAATGGGTGTATGTGCCCCGAGTCTTTTGGCGATATGCAACGCCCCGAGTGCTGACCCTAGAGTATGTTCCAGGTCTCAA
AATTAGTAATTATGATGCCATTGATGCAGCTGGTATCGATCGGAAGCGAATTGCCCAACTGAGTGCTAAAGCCTATCTTT
ATCAGTTATTGACGGATGGTTTTTTCCATGCGGATCCACATCCTGGCAACTTAGCTGTGAGTTCGGATGGAAAGCTGATC
TTCTATGATTTTGGCATGATGGGCCAGATTACGACGCTGACCCGAGAGAAGCTGCTAAAGACGTTTTTCGGGTTTGCTCA
AAAAGATGCCAATAAAGTGATTGCTTCTTTGATCGATTTAGGGGCACTATTACCTGTAGATGATATGGGTCCGATCCGAC
GCTCGATCCAATATATGTTGGATAATTTTATGGGGCAGCCGTTTGATAAACAGTCTGTTGCTCAAATTGGCGATGATCTA
TTTGAGATTGCTTATGATCAACCCTTTCGTTTCCCCGCAACGTTTACATTTGTCATGCGGGCCTTTTCCACTTTAGAAGG
GGTGGGGCGAGGTTTAGATCCTACGTTTAACTTTATGGAGGTTGCAGAACCCTTTGCAGCAGAACTTATGACCAACGGTG
GATTTTCAAATAATCAAAATGGTGATCTGTTGGGAGAGTTGGGGCGGCAGGCTGCCCAGGTTAGTAATACTGCCTTGGGC
CTACCCCGACGGATGGAAGATACCCTGGACAAGCTAGAGCAGGGTGATCTCCGAATGCGAGTGCGCTCAGTGGAAACAGA
CCGGATTTTGCGGCGGCTTAATTTAACCCATATGGGAACCAACTATGCTTTGCTGATTGGTGCTTTTACACTCTCTGCAA
CGATTCTGCTGGTTAATAAGTATGTGTGGCTGGCTGCGATTGCAGCTCTAGCTGCCAGTGTCGCTGCTATTGTCTTCTTG
CGGCTGTTATTAAGAATGAAACGTTATGACAGTTTTGAACGAATGTTGTAG

Upstream 100 bases:

>100_bases
CTGCTAATTCTGGTGATTTACAAGAGACCATTGATGAGTTGCGGGCAGAAATTGCCCAGCTCCGTTCAGCTCTGCAAAAC
TACCGCAGCCATTCTGGTTA

Downstream 100 bases:

>100_bases
CATTTTAGAGGCAAATCAGGAAAGGTGCTTTTTTCGCTACACTATTTGAATGTCTGAGGCTTTATATCATCTTCCTAAAT
TGACGCAGATGGTAATCACA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MPVSVSSSELTFPKQNRKAYRWNRESYSRQRRFLDIWAFVLQLLSSRWWLSKSWSYAGGMTEDKRATRRRKQAVWIRETL
LDLGPTFIKVGQLFSTRADLFPAEYVEELSKLQDRVPAFSYEIVERIIEKDFGRTIPELFCSFDPVPLAAASLGQVHRAQ
LQSGEEVVVKIQRPGLKKLFDIDLRILKGIAHYFQNHPKWGPGRDWLGIYEECCKILYEEIDYLNEGRNADQFRRNFREQ
EWVYVPRVFWRYATPRVLTLEYVPGLKISNYDAIDAAGIDRKRIAQLSAKAYLYQLLTDGFFHADPHPGNLAVSSDGKLI
FYDFGMMGQITTLTREKLLKTFFGFAQKDANKVIASLIDLGALLPVDDMGPIRRSIQYMLDNFMGQPFDKQSVAQIGDDL
FEIAYDQPFRFPATFTFVMRAFSTLEGVGRGLDPTFNFMEVAEPFAAELMTNGGFSNNQNGDLLGELGRQAAQVSNTALG
LPRRMEDTLDKLEQGDLRMRVRSVETDRILRRLNLTHMGTNYALLIGAFTLSATILLVNKYVWLAAIAALAASVAAIVFL
RLLLRMKRYDSFERML

Sequences:

>Translated_576_residues
MPVSVSSSELTFPKQNRKAYRWNRESYSRQRRFLDIWAFVLQLLSSRWWLSKSWSYAGGMTEDKRATRRRKQAVWIRETL
LDLGPTFIKVGQLFSTRADLFPAEYVEELSKLQDRVPAFSYEIVERIIEKDFGRTIPELFCSFDPVPLAAASLGQVHRAQ
LQSGEEVVVKIQRPGLKKLFDIDLRILKGIAHYFQNHPKWGPGRDWLGIYEECCKILYEEIDYLNEGRNADQFRRNFREQ
EWVYVPRVFWRYATPRVLTLEYVPGLKISNYDAIDAAGIDRKRIAQLSAKAYLYQLLTDGFFHADPHPGNLAVSSDGKLI
FYDFGMMGQITTLTREKLLKTFFGFAQKDANKVIASLIDLGALLPVDDMGPIRRSIQYMLDNFMGQPFDKQSVAQIGDDL
FEIAYDQPFRFPATFTFVMRAFSTLEGVGRGLDPTFNFMEVAEPFAAELMTNGGFSNNQNGDLLGELGRQAAQVSNTALG
LPRRMEDTLDKLEQGDLRMRVRSVETDRILRRLNLTHMGTNYALLIGAFTLSATILLVNKYVWLAAIAALAASVAAIVFL
RLLLRMKRYDSFERML
>Mature_575_residues
PVSVSSSELTFPKQNRKAYRWNRESYSRQRRFLDIWAFVLQLLSSRWWLSKSWSYAGGMTEDKRATRRRKQAVWIRETLL
DLGPTFIKVGQLFSTRADLFPAEYVEELSKLQDRVPAFSYEIVERIIEKDFGRTIPELFCSFDPVPLAAASLGQVHRAQL
QSGEEVVVKIQRPGLKKLFDIDLRILKGIAHYFQNHPKWGPGRDWLGIYEECCKILYEEIDYLNEGRNADQFRRNFREQE
WVYVPRVFWRYATPRVLTLEYVPGLKISNYDAIDAAGIDRKRIAQLSAKAYLYQLLTDGFFHADPHPGNLAVSSDGKLIF
YDFGMMGQITTLTREKLLKTFFGFAQKDANKVIASLIDLGALLPVDDMGPIRRSIQYMLDNFMGQPFDKQSVAQIGDDLF
EIAYDQPFRFPATFTFVMRAFSTLEGVGRGLDPTFNFMEVAEPFAAELMTNGGFSNNQNGDLLGELGRQAAQVSNTALGL
PRRMEDTLDKLEQGDLRMRVRSVETDRILRRLNLTHMGTNYALLIGAFTLSATILLVNKYVWLAAIAALAASVAAIVFLR
LLLRMKRYDSFERML

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=251, Percent_Identity=33.8645418326693, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=35.0553505535055, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI217035081, Length=249, Percent_Identity=30.9236947791165, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI32261307, Length=337, Percent_Identity=23.4421364985163, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI27363457, Length=350, Percent_Identity=25.1428571428571, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217416386, Length=278, Percent_Identity=25.8992805755396, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI34147522, Length=298, Percent_Identity=25.503355704698, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI2367309, Length=482, Percent_Identity=30.2904564315353, Blast_Score=197, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17559152, Length=309, Percent_Identity=29.4498381877023, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32565180, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555620, Length=298, Percent_Identity=24.8322147651007, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=274, Percent_Identity=28.8321167883212, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6325148, Length=484, Percent_Identity=23.9669421487603, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=240, Percent_Identity=30.8333333333333, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24662575, Length=402, Percent_Identity=31.0945273631841, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI22024280, Length=257, Percent_Identity=33.852140077821, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI18859849, Length=273, Percent_Identity=30.03663003663, Blast_Score=93, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 66085; Mature: 65954

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVSVSSSELTFPKQNRKAYRWNRESYSRQRRFLDIWAFVLQLLSSRWWLSKSWSYAGGM
CCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TEDKRATRRRKQAVWIRETLLDLGPTFIKVGQLFSTRADLFPAEYVEELSKLQDRVPAFS
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
YEIVERIIEKDFGRTIPELFCSFDPVPLAAASLGQVHRAQLQSGEEVVVKIQRPGLKKLF
HHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
DIDLRILKGIAHYFQNHPKWGPGRDWLGIYEECCKILYEEIDYLNEGRNADQFRRNFREQ
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
EWVYVPRVFWRYATPRVLTLEYVPGLKISNYDAIDAAGIDRKRIAQLSAKAYLYQLLTDG
CEEEHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
FFHADPHPGNLAVSSDGKLIFYDFGMMGQITTLTREKLLKTFFGFAQKDANKVIASLIDL
CCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALLPVDDMGPIRRSIQYMLDNFMGQPFDKQSVAQIGDDLFEIAYDQPFRFPATFTFVMR
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AFSTLEGVGRGLDPTFNFMEVAEPFAAELMTNGGFSNNQNGDLLGELGRQAAQVSNTALG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
LPRRMEDTLDKLEQGDLRMRVRSVETDRILRRLNLTHMGTNYALLIGAFTLSATILLVNK
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YVWLAAIAALAASVAAIVFLRLLLRMKRYDSFERML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]