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The map label for this gene is prpC [H]

Identifier: 158338698

GI number: 158338698

Start: 5669536

End: 5670345

Strand: Reverse

Name: prpC [H]

Synonym: AM1_5605

Alternate gene names: 158338698

Gene position: 5670345-5669536 (Counterclockwise)

Preceding gene: 158338699

Following gene: 158338695

Centisome position: 87.19

GC content: 50.12

Gene sequence:

>810_bases
ATGAAACGTCTGTTTGCAGGCCTTAGTGATCAAGGGTTAGTCCGTAAGGCGAACCAGGACTCTTACCGGATTGATGAACC
CGAAGGCCGATTTTTTATCGTGGCGGATGGAATGGGGGGCCATGCAGGTGGCGAAGAAGCGAGCCGGATTGCCGCTGAAA
CCATTCAGAAGTTTTTGGTGGAAAATTGGCAAGCCCAGCTTAATCCACCGGATTTATTGAAAAAGGCACTACTGAAAGCG
AATCAAGATATTATTCAGAATCAAAAAGACTTCCCAGAACGGGCTGACATGGGAACGACCGTTGTGGTGGTCTTATTTCC
TGCAGAAGGTCAACCTTGGTGCGCTCATATTGGTGATTCGCGGTTATATCGATGGAGAGGATCCCAGTTGTCGCAGATTA
CCGAGGATCATACCTGGATTTCCCAAGCTGTGAAATCTGGCTTGTTGACGAAGGATCAAGCGCGAAGCCATCCCTGGCGT
CATGTGCTAGCCCAATGCTTGGGGCGTGAAGAGCTAGATGAAATCGGCATCCAACAGCTTGATGTCAAGTCTGGCGATCA
GTTGTTACTTTGTAGTGATGGCCTCACTGAAGAGTTGGCCGATGAGCAAATTGCACCTTTCTTCGAGGCAAAACATCCCT
GCGAGACGGTTGTAGATGCTTTAGTCGAAGCGGCGAAAGACGAAGGCGGGCAAGACAATATTACCGTTGTGCTTGTTGCC
CTAGGCGATGGTGAAGAAGAGGAAAGTTCGAGCTGGGCTGATACGCCTGCTATGGACGACGACCCTACGGGTGACCTCAA
CGAAGCTTAG

Upstream 100 bases:

>100_bases
TTTCGCTACACTATTTGAATGTCTGAGGCTTTATATCATCTTCCTAAATTGACGCAGATGGTAATCACAGTAGAGGAATT
ATAGAATCGTTGAAACTAAT

Downstream 100 bases:

>100_bases
CGGCTCTTTTGAATGCCTCGCTGCCGGAGTTGTTGGATAAAGAAGTCTTCTAGGGATTGTCGCATCAGTTTCATTTCCAC
CAAAGTGCCTCCCATGCTGT

Product: serine/threonine protein phosphatase 2C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKRLFAGLSDQGLVRKANQDSYRIDEPEGRFFIVADGMGGHAGGEEASRIAAETIQKFLVENWQAQLNPPDLLKKALLKA
NQDIIQNQKDFPERADMGTTVVVVLFPAEGQPWCAHIGDSRLYRWRGSQLSQITEDHTWISQAVKSGLLTKDQARSHPWR
HVLAQCLGREELDEIGIQQLDVKSGDQLLLCSDGLTEELADEQIAPFFEAKHPCETVVDALVEAAKDEGGQDNITVVLVA
LGDGEEEESSSWADTPAMDDDPTGDLNEA

Sequences:

>Translated_269_residues
MKRLFAGLSDQGLVRKANQDSYRIDEPEGRFFIVADGMGGHAGGEEASRIAAETIQKFLVENWQAQLNPPDLLKKALLKA
NQDIIQNQKDFPERADMGTTVVVVLFPAEGQPWCAHIGDSRLYRWRGSQLSQITEDHTWISQAVKSGLLTKDQARSHPWR
HVLAQCLGREELDEIGIQQLDVKSGDQLLLCSDGLTEELADEQIAPFFEAKHPCETVVDALVEAAKDEGGQDNITVVLVA
LGDGEEEESSSWADTPAMDDDPTGDLNEA
>Mature_269_residues
MKRLFAGLSDQGLVRKANQDSYRIDEPEGRFFIVADGMGGHAGGEEASRIAAETIQKFLVENWQAQLNPPDLLKKALLKA
NQDIIQNQKDFPERADMGTTVVVVLFPAEGQPWCAHIGDSRLYRWRGSQLSQITEDHTWISQAVKSGLLTKDQARSHPWR
HVLAQCLGREELDEIGIQQLDVKSGDQLLLCSDGLTEELADEQIAPFFEAKHPCETVVDALVEAAKDEGGQDNITVVLVA
LGDGEEEESSSWADTPAMDDDPTGDLNEA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29636; Mature: 29636

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLFAGLSDQGLVRKANQDSYRIDEPEGRFFIVADGMGGHAGGEEASRIAAETIQKFLV
CCCHHCCCCCCCHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
ENWQAQLNPPDLLKKALLKANQDIIQNQKDFPERADMGTTVVVVLFPAEGQPWCAHIGDS
HHHHCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCCEEECCCC
RLYRWRGSQLSQITEDHTWISQAVKSGLLTKDQARSHPWRHVLAQCLGREELDEIGIQQL
CEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCHHHHHHCCCEEE
DVKSGDQLLLCSDGLTEELADEQIAPFFEAKHPCETVVDALVEAAKDEGGQDNITVVLVA
ECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LGDGEEEESSSWADTPAMDDDPTGDLNEA
ECCCCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRLFAGLSDQGLVRKANQDSYRIDEPEGRFFIVADGMGGHAGGEEASRIAAETIQKFLV
CCCHHCCCCCCCHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
ENWQAQLNPPDLLKKALLKANQDIIQNQKDFPERADMGTTVVVVLFPAEGQPWCAHIGDS
HHHHCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHCCCCEEEEEEECCCCCCCEEECCCC
RLYRWRGSQLSQITEDHTWISQAVKSGLLTKDQARSHPWRHVLAQCLGREELDEIGIQQL
CEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCHHHHHHCCCEEE
DVKSGDQLLLCSDGLTEELADEQIAPFFEAKHPCETVVDALVEAAKDEGGQDNITVVLVA
ECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LGDGEEEESSSWADTPAMDDDPTGDLNEA
ECCCCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]