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The map label for this gene is mshA [H]

Identifier: 158338645

GI number: 158338645

Start: 5599688

End: 5600824

Strand: Reverse

Name: mshA [H]

Synonym: AM1_5549

Alternate gene names: 158338645

Gene position: 5600824-5599688 (Counterclockwise)

Preceding gene: 158338646

Following gene: 158338644

Centisome position: 86.12

GC content: 44.85

Gene sequence:

>1137_bases
ATGAAAAATCTTCGTATTGCTTGGCTTTTAACTTCAGCAGCTGACTACTGGCATCCGATGCTCAAAAGCCTCTCAGATAT
AAACCCTGATACTCAGGCATTTGTGGCAAATTGGAGAGGATTTGCACCAGGCTATGAAGAGGCCTTCAAAGTTGATATTG
TCGGTGAACGGAAAGTCGTTTCCTTGCGAAAATCAGCGGCGAGTTACGGTGACAATTTCACCGTCATGCCCCTAAATATC
GTCAACCGCTTACTGAAATTCAAGCCTGATGTGATCTTCTGCAACTCCTTTGGGGTTTGGACGATTCTGGCACTCTTGTC
TAAACCCATCGGCAAATGGCGGGTCGTGATTGCCTATGAAGGTAGTTCGCCCGGAGTAGATTATCGAAATTCCAACCTGA
GATTGTCGATTCGCAAAGCAATGGTCCGGGCAGCTGATGCCTGTATTACGAATAGCCATGCTGGCAAACAGTATTTAGAA
GAATGCCTTGCAGCGTCTGCCGAGCTTGTTCATTTACATCCTTATGAGGTTCCTTCCGGCAATGCGCTCCAGGCCTCTTC
TGCAGGGGAGGATTTAAGTCATCTTGAATTTAAACGACCCATTTTTATATTTGTTGGAAGTGTGAGTGTTCGTAAAGGGA
TTTCTTTACTCCTTAAGGCGTGCACCTCTTTAGTTCAAGACGGGTGTCAGCCCTTCACGGTGATGATTGTAGGAGATGGT
GATCAACGCCAAGGATTAGAGGAATATTGTCGCACCCATAACTTGGAAGACTACGTCAAATGGATAGGGAAAGTCGATTA
TCAGAAATTAGGGGCGTATTTTGGTTATGCAGATATATTCGTATTACCAACGTTGGAAGACACTTGGGGGATGGTTGTCT
TAGAATCCATGGCTGTGGGTAAGGCCATTCTTTGCTCTCAGTTTGCTGGAGCCTCGGAATTGGTAGCAAATGACGATAAT
GGCTATATATTCGATCCTAATGATACAAATGCATTCGCATCTGTAATGAAGAAGTTTGTAGATGACCCCTCTTTAAGTCA
GCGTATGGGAGAACGGTCATCACAAATCATGGCTCAATATACTCCTGAAGCCGCAGCAGAATTCCTTGCTAGCGTTGCTA
AAGGCACATTGCAATAA

Upstream 100 bases:

>100_bases
ATGATTGAACTAAATGAATAATACGAAGCCAGAATAAACCTCACATTCGCCTTACTAGTTGATGTTTCGAGTTTGGAACT
GCTCTACCCCCATACATGAA

Downstream 100 bases:

>100_bases
AGGTGATTTCTGCTAATGTCTCAACGCTTGAATGTGTTGATTTCTGCTTATGCCTGCCGACCCCATGAAGGGTCTGAGCC
TGGAGTAGGTTGGAATTTGG

Product: glycosyl transferase, group 1 family protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKNLRIAWLLTSAADYWHPMLKSLSDINPDTQAFVANWRGFAPGYEEAFKVDIVGERKVVSLRKSAASYGDNFTVMPLNI
VNRLLKFKPDVIFCNSFGVWTILALLSKPIGKWRVVIAYEGSSPGVDYRNSNLRLSIRKAMVRAADACITNSHAGKQYLE
ECLAASAELVHLHPYEVPSGNALQASSAGEDLSHLEFKRPIFIFVGSVSVRKGISLLLKACTSLVQDGCQPFTVMIVGDG
DQRQGLEEYCRTHNLEDYVKWIGKVDYQKLGAYFGYADIFVLPTLEDTWGMVVLESMAVGKAILCSQFAGASELVANDDN
GYIFDPNDTNAFASVMKKFVDDPSLSQRMGERSSQIMAQYTPEAAAEFLASVAKGTLQ

Sequences:

>Translated_378_residues
MKNLRIAWLLTSAADYWHPMLKSLSDINPDTQAFVANWRGFAPGYEEAFKVDIVGERKVVSLRKSAASYGDNFTVMPLNI
VNRLLKFKPDVIFCNSFGVWTILALLSKPIGKWRVVIAYEGSSPGVDYRNSNLRLSIRKAMVRAADACITNSHAGKQYLE
ECLAASAELVHLHPYEVPSGNALQASSAGEDLSHLEFKRPIFIFVGSVSVRKGISLLLKACTSLVQDGCQPFTVMIVGDG
DQRQGLEEYCRTHNLEDYVKWIGKVDYQKLGAYFGYADIFVLPTLEDTWGMVVLESMAVGKAILCSQFAGASELVANDDN
GYIFDPNDTNAFASVMKKFVDDPSLSQRMGERSSQIMAQYTPEAAAEFLASVAKGTLQ
>Mature_378_residues
MKNLRIAWLLTSAADYWHPMLKSLSDINPDTQAFVANWRGFAPGYEEAFKVDIVGERKVVSLRKSAASYGDNFTVMPLNI
VNRLLKFKPDVIFCNSFGVWTILALLSKPIGKWRVVIAYEGSSPGVDYRNSNLRLSIRKAMVRAADACITNSHAGKQYLE
ECLAASAELVHLHPYEVPSGNALQASSAGEDLSHLEFKRPIFIFVGSVSVRKGISLLLKACTSLVQDGCQPFTVMIVGDG
DQRQGLEEYCRTHNLEDYVKWIGKVDYQKLGAYFGYADIFVLPTLEDTWGMVVLESMAVGKAILCSQFAGASELVANDDN
GYIFDPNDTNAFASVMKKFVDDPSLSQRMGERSSQIMAQYTPEAAAEFLASVAKGTLQ

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 41731; Mature: 41731

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLRIAWLLTSAADYWHPMLKSLSDINPDTQAFVANWRGFAPGYEEAFKVDIVGERKVV
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHCEEEEEECCHHHH
SLRKSAASYGDNFTVMPLNIVNRLLKFKPDVIFCNSFGVWTILALLSKPIGKWRVVIAYE
HHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEEC
GSSPGVDYRNSNLRLSIRKAMVRAADACITNSHAGKQYLEECLAASAELVHLHPYEVPSG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
NALQASSAGEDLSHLEFKRPIFIFVGSVSVRKGISLLLKACTSLVQDGCQPFTVMIVGDG
CEEECCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DQRQGLEEYCRTHNLEDYVKWIGKVDYQKLGAYFGYADIFVLPTLEDTWGMVVLESMAVG
HHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHH
KAILCSQFAGASELVANDDNGYIFDPNDTNAFASVMKKFVDDPSLSQRMGERSSQIMAQY
HHHHHHHHCCCHHHEEECCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHC
TPEAAAEFLASVAKGTLQ
CHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNLRIAWLLTSAADYWHPMLKSLSDINPDTQAFVANWRGFAPGYEEAFKVDIVGERKVV
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHCEEEEEECCHHHH
SLRKSAASYGDNFTVMPLNIVNRLLKFKPDVIFCNSFGVWTILALLSKPIGKWRVVIAYE
HHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEEC
GSSPGVDYRNSNLRLSIRKAMVRAADACITNSHAGKQYLEECLAASAELVHLHPYEVPSG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
NALQASSAGEDLSHLEFKRPIFIFVGSVSVRKGISLLLKACTSLVQDGCQPFTVMIVGDG
CEEECCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DQRQGLEEYCRTHNLEDYVKWIGKVDYQKLGAYFGYADIFVLPTLEDTWGMVVLESMAVG
HHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHH
KAILCSQFAGASELVANDDNGYIFDPNDTNAFASVMKKFVDDPSLSQRMGERSSQIMAQY
HHHHHHHHCCCHHHEEECCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHC
TPEAAAEFLASVAKGTLQ
CHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]