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The map label for this gene is ahpC [C]

Identifier: 158338591

GI number: 158338591

Start: 5547781

End: 5548416

Strand: Reverse

Name: ahpC [C]

Synonym: AM1_5494

Alternate gene names: 158338591

Gene position: 5548416-5547781 (Counterclockwise)

Preceding gene: 158338592

Following gene: 158338590

Centisome position: 85.31

GC content: 47.48

Gene sequence:

>636_bases
ATGTCTTTGCGACTAGGGGACACCGTACCTAACTTTACTCAAGATTCCACTGCTGGCACAATTGACTTCTTTGAATGGGC
TGGCGATAGCTGGGTTGTTCTCTTCTCGCATCCTGCGGACTACACCCCCGTTTGTACGACTGAGCTCGGGTCTGTCTCTA
AGCTTAAGCCTGAGTTTGACAAGCGCCACGTCAAAACCATTGCCCTGAGCGTCGATGATGCTCAGGCCCACAACGGCTGG
ATTGGCGATATCAATGAAACCCAAAATACAACCGTTGATTACCCTATCTTGGCGGATGCGGACAAGAAAGTGTCTGATCT
ATACGACATGATTCATCCCAACGCCAACGCCAAAGTCACTGTCAGAACAGTATTTATTATTGACAACAATAAAAAGCTCA
GAGCCTCCATTACCTACCCACCTAGCACAGGTCGGAATTTTAATGAGATCCTGCGGGTCATTGACTCACTCCAATTGACC
GATAACTATCAAGTTGCTACTCCCGTAGACTGGCAAGATGGTGATGATGTCGTCGTTGCTCCCACCATTCCTACAGAAGA
AGCCAAGCAGAAATTCCCCAAAGGGGTCACTGAAATCAAGCCTTATTTACGGATGACTCCTCAACCCAACAAATAA

Upstream 100 bases:

>100_bases
GAACTGTTTCTCGGTCGGGAAACCGGACATTATCCGAATTCGGTTATGGCATGATCTCATTTGTAACCACAAACCGACCT
TTCATGACAGGAGTTTCACC

Downstream 100 bases:

>100_bases
GCCTTTCGTGATTTAGACTGCGATTTCCAACCCCCGTCAGGGGGTTTTTTATTGTCCAAGGTCTGGGCAGGGCAATCTTG
CTTTTCTGTTCAAGAGACAA

Product: alkyl hydroperoxide reductase/Thiol specific antioxidant family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSLRLGDTVPNFTQDSTAGTIDFFEWAGDSWVVLFSHPADYTPVCTTELGSVSKLKPEFDKRHVKTIALSVDDAQAHNGW
IGDINETQNTTVDYPILADADKKVSDLYDMIHPNANAKVTVRTVFIIDNNKKLRASITYPPSTGRNFNEILRVIDSLQLT
DNYQVATPVDWQDGDDVVVAPTIPTEEAKQKFPKGVTEIKPYLRMTPQPNK

Sequences:

>Translated_211_residues
MSLRLGDTVPNFTQDSTAGTIDFFEWAGDSWVVLFSHPADYTPVCTTELGSVSKLKPEFDKRHVKTIALSVDDAQAHNGW
IGDINETQNTTVDYPILADADKKVSDLYDMIHPNANAKVTVRTVFIIDNNKKLRASITYPPSTGRNFNEILRVIDSLQLT
DNYQVATPVDWQDGDDVVVAPTIPTEEAKQKFPKGVTEIKPYLRMTPQPNK
>Mature_210_residues
SLRLGDTVPNFTQDSTAGTIDFFEWAGDSWVVLFSHPADYTPVCTTELGSVSKLKPEFDKRHVKTIALSVDDAQAHNGWI
GDINETQNTTVDYPILADADKKVSDLYDMIHPNANAKVTVRTVFIIDNNKKLRASITYPPSTGRNFNEILRVIDSLQLTD
NYQVATPVDWQDGDDVVVAPTIPTEEAKQKFPKGVTEIKPYLRMTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=52.9411764705882, Blast_Score=224, Evalue=5e-59,
Organism=Homo sapiens, GI32189392, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4505591, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI32455266, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI32455264, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI5453549, Length=163, Percent_Identity=28.2208588957055, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI32483377, Length=142, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI5802974, Length=142, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25153706, Length=203, Percent_Identity=39.9014778325123, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17554494, Length=165, Percent_Identity=28.4848484848485, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193204376, Length=170, Percent_Identity=28.8235294117647, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32565831, Length=170, Percent_Identity=28.8235294117647, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319407, Length=211, Percent_Identity=52.132701421801, Blast_Score=223, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323613, Length=163, Percent_Identity=27.6073619631902, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581278, Length=218, Percent_Identity=51.3761467889908, Blast_Score=227, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24652434, Length=208, Percent_Identity=48.0769230769231, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI17975518, Length=208, Percent_Identity=48.0769230769231, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24652436, Length=208, Percent_Identity=47.1153846153846, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=28.3505154639175, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17157991, Length=151, Percent_Identity=32.4503311258278, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641739, Length=151, Percent_Identity=32.4503311258278, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17738015, Length=199, Percent_Identity=28.1407035175879, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656348, Length=163, Percent_Identity=31.9018404907975, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864676, Length=163, Percent_Identity=31.9018404907975, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23569; Mature: 23437

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDTVPNFTQDSTAGTIDFFEWAGDSWVVLFSHPADYTPVCTTELGSVSKLKPEFD
CCEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHH
KRHVKTIALSVDDAQAHNGWIGDINETQNTTVDYPILADADKKVSDLYDMIHPNANAKVT
HCEEEEEEEEECCCCCCCCEECCCCCCCCCEECCCEEECCCHHHHHHHHHHCCCCCCEEE
VRTVFIIDNNKKLRASITYPPSTGRNFNEILRVIDSLQLTDNYQVATPVDWQDGDDVVVA
EEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEE
PTIPTEEAKQKFPKGVTEIKPYLRMTPQPNK
CCCCCHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
SLRLGDTVPNFTQDSTAGTIDFFEWAGDSWVVLFSHPADYTPVCTTELGSVSKLKPEFD
CEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCCCHH
KRHVKTIALSVDDAQAHNGWIGDINETQNTTVDYPILADADKKVSDLYDMIHPNANAKVT
HCEEEEEEEEECCCCCCCCEECCCCCCCCCEECCCEEECCCHHHHHHHHHHCCCCCCEEE
VRTVFIIDNNKKLRASITYPPSTGRNFNEILRVIDSLQLTDNYQVATPVDWQDGDDVVVA
EEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEE
PTIPTEEAKQKFPKGVTEIKPYLRMTPQPNK
CCCCCHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]