Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 158338315

GI number: 158338315

Start: 5273686

End: 5275596

Strand: Reverse

Name: yciR [C]

Synonym: AM1_5211

Alternate gene names: 158338315

Gene position: 5275596-5273686 (Counterclockwise)

Preceding gene: 158338316

Following gene: 158338313

Centisome position: 81.12

GC content: 48.14

Gene sequence:

>1911_bases
ATGACACTGAATACACCTGCATCCCAAACGGTGGATTTGCCTACAGATGACGAGTCGAAAGGCTTGATTTTGATTGTTGA
TGATACGCCCCACAACTTACAAATCTTATCCACGGCGTTGACTAAACAAGGCTATCAAGTGCGAGGGGCCGCCAATGGTT
CCATGGCACTGATTGGGGCAAGGAACATTATGCCCGACTTGATCTTGCTGGATATCAAGATGCCAGAAATGGATGGCTAT
ACCGTTTGTGAACGCTTGAAATCAGAAGCCTTAACGCAAGATATCCCAGTCATTTTTATTAGCGCCTTAGACGATGCCTT
GGATAAGGTCAAAGCGTTCACGGTGGGTGGGGTGGACTATATCACCAAGCCCTTTCAATTGGCTGAGATTTTGGCTCGGG
TGGAAAATCAACTGACCATTGGTCGGCTGCAAAAAGAACAGCGTAAACAAAATGAACGACTGCAGGCCGAGGTGCGCGAT
CGCATCGCTGCTGAAGCCCAAATCCAAGCCCTTAATGCTGACTTAGAGCAAAGAGTAGTTCAGCGGACGGAGCGGCTGAA
TCAGGAAATTGCTGAGCGGGAGAAAGTACAGCAGCAATTAAAACATATGGCCATGCACGATCCGTTGACGGATCTGCCCA
ACCGGACGTTGTTCCTCACCTGTCTCGAAGAAACGATTCAGGACACCCAAAAACAGACCGATCAATCCTTTGCGCTGCTG
TTTCTGGATTGTGATCGCTTCAAGTCTATTAACGATTCCTTGGGACATTTAGTCGGGGACCAATTTTTAGTTGCGATCGC
AAAACGGTTCCAGCGCTGTGTGGGCGATCAACTCCTAGCCCGCTTAGGAGGCGATGAATTTACGATTCTGCTCAAAAATG
TCTCCAACGAGCAGCAAGCCATCAATATTGCAGATGCCATTCAACGCAGTTTACTAGAGCCGTTTCATATTGGCGACAAC
GAATTCTTTGTCTCTGCCAGTATCGGCATTGTCATGAGCAGCCCAGACTATCAGCAACCCACTGAAATGTTGCGGGATGC
CGATACCGCCATGTATCGAGCCAAAGCCATGGGCAAGGCGCGGCATATCGTCTTCAATGCCAGCATGCATGAAGATGTCC
AAAGTTCTCTACAACTAGAAACAGATTTACGTCGGGCCATCGAACGGCAAGAATTTATTCTCAACTATCAACCGATTGTG
GCTCTGGATACAGGCATGATTACGGGGTTTGAAGCCCTAGTCCGCTGGATCAGCCCAGAGCTAGGCTTTGTTTCCCCAGG
GAAATTTATTCCCCTAGCTGAGGATACAGGCCTCATTATTCCCCTAGGGGAATGGGTGTTACGGGAAGCCTGTCGTCAGC
TGAATGAATGGCAATCCAACAATGTCACGGATATTCCCTTGACCATGAGCGTCAATTTATCCGTTAAGCAATTCTCTCAA
CCCAACCTGATCGAAACCATTGACCAAATTTTGGCAGAGACCCAACTTCCGACCCAGTGCCTAAAGTTGGAAATTACCGA
AAGCGCCATTATGGAGAATTCTGACTCCGCGGCCAAGATTCTCGATCAGCTAAGAGACCGCCAGATTCACTTAAGTATTG
ATGATTTTGGTACAGGCTATTCTTCCTTAAGTTACTTGCATCGGTTCCCCGTCAATACCTTGAAGGTGGATCGATCCTTT
GTCTGTCGATTGGATGCCGCAGACGATAACGTGGCCATTGTTCAGGCCATTGTCACCTTGGCCCAAACCATGGGAATGGA
TGTGGTCGCGGAAGGGATTGAAACGACAGAGCAGCAACATCAGCTGGAAAACTTAGGGTGTGAATATGGGCAGGGATATC
TGTTTTGCAAGCCTGTGAATGCCGAAACAGCCGGTGAAATGCTAGCCAACAGAAATCACAAGTTGTTTTAG

Upstream 100 bases:

>100_bases
TTTCTTCTGTCGTGTCGAAAGTTCCTGAAGTATCCGAACTGGGTACACTAAAGTGCAAGCTGAGCATCTCGTTCCACTCC
TTTTTTAGCCGAATTTAGCC

Downstream 100 bases:

>100_bases
GGGCTAGGCCACTTTTTATCGTTCTCTTATCCCCGGCGGCTCCGATTTTCCTCGGTCGAGCTGGGCCAAACTAGGCAGAC
TTAGCGGCGTTGAAACATGC

Product: diguanylate cyclase/phosphodiesterase with response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTLNTPASQTVDLPTDDESKGLILIVDDTPHNLQILSTALTKQGYQVRGAANGSMALIGARNIMPDLILLDIKMPEMDGY
TVCERLKSEALTQDIPVIFISALDDALDKVKAFTVGGVDYITKPFQLAEILARVENQLTIGRLQKEQRKQNERLQAEVRD
RIAAEAQIQALNADLEQRVVQRTERLNQEIAEREKVQQQLKHMAMHDPLTDLPNRTLFLTCLEETIQDTQKQTDQSFALL
FLDCDRFKSINDSLGHLVGDQFLVAIAKRFQRCVGDQLLARLGGDEFTILLKNVSNEQQAINIADAIQRSLLEPFHIGDN
EFFVSASIGIVMSSPDYQQPTEMLRDADTAMYRAKAMGKARHIVFNASMHEDVQSSLQLETDLRRAIERQEFILNYQPIV
ALDTGMITGFEALVRWISPELGFVSPGKFIPLAEDTGLIIPLGEWVLREACRQLNEWQSNNVTDIPLTMSVNLSVKQFSQ
PNLIETIDQILAETQLPTQCLKLEITESAIMENSDSAAKILDQLRDRQIHLSIDDFGTGYSSLSYLHRFPVNTLKVDRSF
VCRLDAADDNVAIVQAIVTLAQTMGMDVVAEGIETTEQQHQLENLGCEYGQGYLFCKPVNAETAGEMLANRNHKLF

Sequences:

>Translated_636_residues
MTLNTPASQTVDLPTDDESKGLILIVDDTPHNLQILSTALTKQGYQVRGAANGSMALIGARNIMPDLILLDIKMPEMDGY
TVCERLKSEALTQDIPVIFISALDDALDKVKAFTVGGVDYITKPFQLAEILARVENQLTIGRLQKEQRKQNERLQAEVRD
RIAAEAQIQALNADLEQRVVQRTERLNQEIAEREKVQQQLKHMAMHDPLTDLPNRTLFLTCLEETIQDTQKQTDQSFALL
FLDCDRFKSINDSLGHLVGDQFLVAIAKRFQRCVGDQLLARLGGDEFTILLKNVSNEQQAINIADAIQRSLLEPFHIGDN
EFFVSASIGIVMSSPDYQQPTEMLRDADTAMYRAKAMGKARHIVFNASMHEDVQSSLQLETDLRRAIERQEFILNYQPIV
ALDTGMITGFEALVRWISPELGFVSPGKFIPLAEDTGLIIPLGEWVLREACRQLNEWQSNNVTDIPLTMSVNLSVKQFSQ
PNLIETIDQILAETQLPTQCLKLEITESAIMENSDSAAKILDQLRDRQIHLSIDDFGTGYSSLSYLHRFPVNTLKVDRSF
VCRLDAADDNVAIVQAIVTLAQTMGMDVVAEGIETTEQQHQLENLGCEYGQGYLFCKPVNAETAGEMLANRNHKLF
>Mature_635_residues
TLNTPASQTVDLPTDDESKGLILIVDDTPHNLQILSTALTKQGYQVRGAANGSMALIGARNIMPDLILLDIKMPEMDGYT
VCERLKSEALTQDIPVIFISALDDALDKVKAFTVGGVDYITKPFQLAEILARVENQLTIGRLQKEQRKQNERLQAEVRDR
IAAEAQIQALNADLEQRVVQRTERLNQEIAEREKVQQQLKHMAMHDPLTDLPNRTLFLTCLEETIQDTQKQTDQSFALLF
LDCDRFKSINDSLGHLVGDQFLVAIAKRFQRCVGDQLLARLGGDEFTILLKNVSNEQQAINIADAIQRSLLEPFHIGDNE
FFVSASIGIVMSSPDYQQPTEMLRDADTAMYRAKAMGKARHIVFNASMHEDVQSSLQLETDLRRAIERQEFILNYQPIVA
LDTGMITGFEALVRWISPELGFVSPGKFIPLAEDTGLIIPLGEWVLREACRQLNEWQSNNVTDIPLTMSVNLSVKQFSQP
NLIETIDQILAETQLPTQCLKLEITESAIMENSDSAAKILDQLRDRQIHLSIDDFGTGYSSLSYLHRFPVNTLKVDRSFV
CRLDAADDNVAIVQAIVTLAQTMGMDVVAEGIETTEQQHQLENLGCEYGQGYLFCKPVNAETAGEMLANRNHKLF

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=37.2413793103448, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI87081921, Length=480, Percent_Identity=35.625, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI226510982, Length=495, Percent_Identity=27.6767676767677, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=35.9504132231405, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787055, Length=248, Percent_Identity=34.6774193548387, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=35, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1790496, Length=244, Percent_Identity=34.8360655737705, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=31.8897637795276, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1786507, Length=234, Percent_Identity=34.1880341880342, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=32.0833333333333, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788381, Length=343, Percent_Identity=30.9037900874636, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=30.2788844621514, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87082096, Length=452, Percent_Identity=26.9911504424779, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=35.7954545454545, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=37.1069182389937, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=34.7058823529412, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=31.2849162011173, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081977, Length=296, Percent_Identity=27.027027027027, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=37.8787878787879, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786584, Length=166, Percent_Identity=30.7228915662651, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788394, Length=135, Percent_Identity=34.0740740740741, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=183, Percent_Identity=32.7868852459016, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=37.1681415929204, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=35.3982300884956, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=31.9526627218935, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=29.8013245033113, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=150, Percent_Identity=31.3333333333333, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=34.4827586206897, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=35.2941176470588, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787229, Length=120, Percent_Identity=34.1666666666667, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=120, Percent_Identity=36.6666666666667, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790860, Length=116, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=36.2068965517241, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=35.3448275862069, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787375, Length=113, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=29.2993630573248, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=122, Percent_Identity=34.4262295081967, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87082007, Length=173, Percent_Identity=33.5260115606936, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71307; Mature: 71176

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNTPASQTVDLPTDDESKGLILIVDDTPHNLQILSTALTKQGYQVRGAANGSMALIGA
CCCCCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEC
RNIMPDLILLDIKMPEMDGYTVCERLKSEALTQDIPVIFISALDDALDKVKAFTVGGVDY
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHEECCHHH
ITKPFQLAEILARVENQLTIGRLQKEQRKQNERLQAEVRDRIAAEAQIQALNADLEQRVV
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QRTERLNQEIAEREKVQQQLKHMAMHDPLTDLPNRTLFLTCLEETIQDTQKQTDQSFALL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEE
FLDCDRFKSINDSLGHLVGDQFLVAIAKRFQRCVGDQLLARLGGDEFTILLKNVSNEQQA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHH
INIADAIQRSLLEPFHIGDNEFFVSASIGIVMSSPDYQQPTEMLRDADTAMYRAKAMGKA
HHHHHHHHHHHCCCEECCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
RHIVFNASMHEDVQSSLQLETDLRRAIERQEFILNYQPIVALDTGMITGFEALVRWISPE
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCC
LGFVSPGKFIPLAEDTGLIIPLGEWVLREACRQLNEWQSNNVTDIPLTMSVNLSVKQFSQ
CCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHCCC
PNLIETIDQILAETQLPTQCLKLEITESAIMENSDSAAKILDQLRDRQIHLSIDDFGTGY
CCHHHHHHHHHHHCCCCHHHHEEEEHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCH
SSLSYLHRFPVNTLKVDRSFVCRLDAADDNVAIVQAIVTLAQTMGMDVVAEGIETTEQQH
HHHHHHHHCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLENLGCEYGQGYLFCKPVNAETAGEMLANRNHKLF
HHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLNTPASQTVDLPTDDESKGLILIVDDTPHNLQILSTALTKQGYQVRGAANGSMALIGA
CCCCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEC
RNIMPDLILLDIKMPEMDGYTVCERLKSEALTQDIPVIFISALDDALDKVKAFTVGGVDY
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHEECCHHH
ITKPFQLAEILARVENQLTIGRLQKEQRKQNERLQAEVRDRIAAEAQIQALNADLEQRVV
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QRTERLNQEIAEREKVQQQLKHMAMHDPLTDLPNRTLFLTCLEETIQDTQKQTDQSFALL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEE
FLDCDRFKSINDSLGHLVGDQFLVAIAKRFQRCVGDQLLARLGGDEFTILLKNVSNEQQA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHH
INIADAIQRSLLEPFHIGDNEFFVSASIGIVMSSPDYQQPTEMLRDADTAMYRAKAMGKA
HHHHHHHHHHHCCCEECCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
RHIVFNASMHEDVQSSLQLETDLRRAIERQEFILNYQPIVALDTGMITGFEALVRWISPE
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCC
LGFVSPGKFIPLAEDTGLIIPLGEWVLREACRQLNEWQSNNVTDIPLTMSVNLSVKQFSQ
CCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHCCC
PNLIETIDQILAETQLPTQCLKLEITESAIMENSDSAAKILDQLRDRQIHLSIDDFGTGY
CCHHHHHHHHHHHCCCCHHHHEEEEHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCH
SSLSYLHRFPVNTLKVDRSFVCRLDAADDNVAIVQAIVTLAQTMGMDVVAEGIETTEQQH
HHHHHHHHCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLENLGCEYGQGYLFCKPVNAETAGEMLANRNHKLF
HHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]