Click here to switch to the map view.

The map label for this gene is lldP [C]

Identifier: 158338205

GI number: 158338205

Start: 5152365

End: 5154035

Strand: Direct

Name: lldP [C]

Synonym: AM1_5099

Alternate gene names: 158338205

Gene position: 5152365-5154035 (Clockwise)

Preceding gene: 158338204

Following gene: 158338207

Centisome position: 79.22

GC content: 53.56

Gene sequence:

>1671_bases
ATGATCTTCCTCTACTCGTTGGTCGCATTGATCCCCATTGCAACAGTATTCTTGCTGTTGGTGGTGGCTCGGCGGCCTGC
GAGTCAAGCCATGCCTTTGTCTTACCTAGTGACGGTTGGTATTGCGTTGGGCGTTTGGCGGGTTCCTGGGGTAGAAGTGG
CCGCCTCTAGTCTTCAGGGCTTGGTGGCCGCGGCTGAGATTCTGTATATCGTTTTCGGCGCAATTTTGCTGCTCAATACC
CTACAAGAATCCGGTGCGATCTCAACCATTCGCCAAAGTTTATTAGGTATCTCCCCCGATCCTAGGGTGCAGGTGATTAT
CATTGCCTGGTTGTTTGGCAGTTTTATTGAAGGGGCTTCTGGGTTTGGTACCCCTGCAGTAATTACCGTGCCGTTGTTGG
TCGCCATTGGCTTTCCGGCCATGGCCGCCGTGGTGGCTGCGTTAATTATTCAGAGTACGCCTTCGACCTTTGGGGCAGTG
GGGACGCCGATCATTATCGGTATTGAAGCGGGCTTAGACGGTGTGCCTGCAGTCAAGGAACAGCTGGTTGAATTAGGATT
AACTCAACCTGAGTATCTGACCCTGATTGGGCGATGGGCTGGTCTGATGCATGGTGTCGTGGGGACTTTTCTGCCCCTGG
TTCTCGTGATGGTACTCACGGCTGGTTTTGGGGCACGTCGATCCCTTAGGGATGGGCTAGGGGCATGGAAGTTTGCCTTG
TTTGCCGGACTTGCGTTTACGATTCCCTATACCCTAACCGCTTACTTTCTGGGACCGGAATTCCCTACTTTGATTGGGGG
GTTAGTGGGGTTGGGGCTGGTGATTCCTGCTGCTCAGAGGGGGCTGTTTACCCCTCAAACCCTTTGGGAATTTCCGTCCG
AATCAGAGGTCAATCCCGCCCCCTTGGTCAGCAACCCACCCCAAAGCGGTCTGACTGCTCGGCAAGCATGGTTGCCCTAT
GGGTTACTGGGGGGTTTTTTACTATTGTCGCGTCTGGAGTTTTTGCCCCTTCGCAGGGGACTGCAGTCTTTATCGCTAAC
TTGGACGAATATCTTGGGGACAGAGGTCGGTGCTGCGACGCGGCCTCTCTACCTGCCGCCAACGGTTTTTCTTCTGGTGG
TCATGATTACGTTTTATCTGCATCGGATGTCGATTCAATCGATGCAGCGAGCGGTCATCCGAACCCTGCCCATCTTGCAA
AAGACAGCGCTGGCCTTGGGGTCGGCAGTTCTGATGGCCAGGGTATTTATCAACACAGGTATCAATTCAGCCGGTCTGGC
GAGTATGCCCCTGGCGTTAGCGGAGGGTATGGCAACCCTCGCGGGGCAATCCTGGCCGTTTTTTGCCCCGATGGTGGGGA
TGGTGGGGTCCTTTGTGGCGGGGAGTGTAACTGTAAGCAATATGATGTTTGCGCTCTTTCAATTTGGGGTTGCCTCCCAA
ATCGATGTACCGACGGCAGTGATCTTAGGGCTGCAATGTGTGGGAGCCTCTGCTGGCAATATGATCTGTGTGTCCAATAT
TGTCACGGCGGAAGCGACGGTTGGTCTGGCGGGCTGTGAAGGTCTGCTGATTCGAAAAGTCTTGATGCCGACACTGTACT
ATTTGATTTTTGCAGGTATTTTAGGTGGATTAATTGTCCTGCTGGCCCCAATCGTTATAGGTAGCAGCTAG

Upstream 100 bases:

>100_bases
CATACCTGTTGATTGAAGAGGGTGAGTAGATGTATCCCTCTGCTGGATTAGGTGCTCAGCCCTTTATGTCATCCACCCAT
GCTGGGTTGGATAAACCTAA

Downstream 100 bases:

>100_bases
CGAAGTGGGGGTGTAAAGACATTGCGAAGGGTTCAAAACTCACATTTTTAGGTCGGGAGTAATCCAACGATTAATCCCAA
AACTGCACCGAGCGGGACTA

Product: L-lactate permease

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MIFLYSLVALIPIATVFLLLVVARRPASQAMPLSYLVTVGIALGVWRVPGVEVAASSLQGLVAAAEILYIVFGAILLLNT
LQESGAISTIRQSLLGISPDPRVQVIIIAWLFGSFIEGASGFGTPAVITVPLLVAIGFPAMAAVVAALIIQSTPSTFGAV
GTPIIIGIEAGLDGVPAVKEQLVELGLTQPEYLTLIGRWAGLMHGVVGTFLPLVLVMVLTAGFGARRSLRDGLGAWKFAL
FAGLAFTIPYTLTAYFLGPEFPTLIGGLVGLGLVIPAAQRGLFTPQTLWEFPSESEVNPAPLVSNPPQSGLTARQAWLPY
GLLGGFLLLSRLEFLPLRRGLQSLSLTWTNILGTEVGAATRPLYLPPTVFLLVVMITFYLHRMSIQSMQRAVIRTLPILQ
KTALALGSAVLMARVFINTGINSAGLASMPLALAEGMATLAGQSWPFFAPMVGMVGSFVAGSVTVSNMMFALFQFGVASQ
IDVPTAVILGLQCVGASAGNMICVSNIVTAEATVGLAGCEGLLIRKVLMPTLYYLIFAGILGGLIVLLAPIVIGSS

Sequences:

>Translated_556_residues
MIFLYSLVALIPIATVFLLLVVARRPASQAMPLSYLVTVGIALGVWRVPGVEVAASSLQGLVAAAEILYIVFGAILLLNT
LQESGAISTIRQSLLGISPDPRVQVIIIAWLFGSFIEGASGFGTPAVITVPLLVAIGFPAMAAVVAALIIQSTPSTFGAV
GTPIIIGIEAGLDGVPAVKEQLVELGLTQPEYLTLIGRWAGLMHGVVGTFLPLVLVMVLTAGFGARRSLRDGLGAWKFAL
FAGLAFTIPYTLTAYFLGPEFPTLIGGLVGLGLVIPAAQRGLFTPQTLWEFPSESEVNPAPLVSNPPQSGLTARQAWLPY
GLLGGFLLLSRLEFLPLRRGLQSLSLTWTNILGTEVGAATRPLYLPPTVFLLVVMITFYLHRMSIQSMQRAVIRTLPILQ
KTALALGSAVLMARVFINTGINSAGLASMPLALAEGMATLAGQSWPFFAPMVGMVGSFVAGSVTVSNMMFALFQFGVASQ
IDVPTAVILGLQCVGASAGNMICVSNIVTAEATVGLAGCEGLLIRKVLMPTLYYLIFAGILGGLIVLLAPIVIGSS
>Mature_556_residues
MIFLYSLVALIPIATVFLLLVVARRPASQAMPLSYLVTVGIALGVWRVPGVEVAASSLQGLVAAAEILYIVFGAILLLNT
LQESGAISTIRQSLLGISPDPRVQVIIIAWLFGSFIEGASGFGTPAVITVPLLVAIGFPAMAAVVAALIIQSTPSTFGAV
GTPIIIGIEAGLDGVPAVKEQLVELGLTQPEYLTLIGRWAGLMHGVVGTFLPLVLVMVLTAGFGARRSLRDGLGAWKFAL
FAGLAFTIPYTLTAYFLGPEFPTLIGGLVGLGLVIPAAQRGLFTPQTLWEFPSESEVNPAPLVSNPPQSGLTARQAWLPY
GLLGGFLLLSRLEFLPLRRGLQSLSLTWTNILGTEVGAATRPLYLPPTVFLLVVMITFYLHRMSIQSMQRAVIRTLPILQ
KTALALGSAVLMARVFINTGINSAGLASMPLALAEGMATLAGQSWPFFAPMVGMVGSFVAGSVTVSNMMFALFQFGVASQ
IDVPTAVILGLQCVGASAGNMICVSNIVTAEATVGLAGCEGLLIRKVLMPTLYYLIFAGILGGLIVLLAPIVIGSS

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=566, Percent_Identity=27.5618374558304, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789347, Length=315, Percent_Identity=29.8412698412698, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 58258; Mature: 58258

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLYSLVALIPIATVFLLLVVARRPASQAMPLSYLVTVGIALGVWRVPGVEVAASSLQG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVAAAEILYIVFGAILLLNTLQESGAISTIRQSLLGISPDPRVQVIIIAWLFGSFIEGAS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCC
GFGTPAVITVPLLVAIGFPAMAAVVAALIIQSTPSTFGAVGTPIIIGIEAGLDGVPAVKE
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHH
QLVELGLTQPEYLTLIGRWAGLMHGVVGTFLPLVLVMVLTAGFGARRSLRDGLGAWKFAL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FAGLAFTIPYTLTAYFLGPEFPTLIGGLVGLGLVIPAAQRGLFTPQTLWEFPSESEVNPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCC
PLVSNPPQSGLTARQAWLPYGLLGGFLLLSRLEFLPLRRGLQSLSLTWTNILGTEVGAAT
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPLYLPPTVFLLVVMITFYLHRMSIQSMQRAVIRTLPILQKTALALGSAVLMARVFINTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INSAGLASMPLALAEGMATLAGQSWPFFAPMVGMVGSFVAGSVTVSNMMFALFQFGVASQ
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDVPTAVILGLQCVGASAGNMICVSNIVTAEATVGLAGCEGLLIRKVLMPTLYYLIFAGI
CCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLIVLLAPIVIGSS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFLYSLVALIPIATVFLLLVVARRPASQAMPLSYLVTVGIALGVWRVPGVEVAASSLQG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVAAAEILYIVFGAILLLNTLQESGAISTIRQSLLGISPDPRVQVIIIAWLFGSFIEGAS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCC
GFGTPAVITVPLLVAIGFPAMAAVVAALIIQSTPSTFGAVGTPIIIGIEAGLDGVPAVKE
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHH
QLVELGLTQPEYLTLIGRWAGLMHGVVGTFLPLVLVMVLTAGFGARRSLRDGLGAWKFAL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FAGLAFTIPYTLTAYFLGPEFPTLIGGLVGLGLVIPAAQRGLFTPQTLWEFPSESEVNPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCC
PLVSNPPQSGLTARQAWLPYGLLGGFLLLSRLEFLPLRRGLQSLSLTWTNILGTEVGAAT
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPLYLPPTVFLLVVMITFYLHRMSIQSMQRAVIRTLPILQKTALALGSAVLMARVFINTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INSAGLASMPLALAEGMATLAGQSWPFFAPMVGMVGSFVAGSVTVSNMMFALFQFGVASQ
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDVPTAVILGLQCVGASAGNMICVSNIVTAEATVGLAGCEGLLIRKVLMPTLYYLIFAGI
CCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLIVLLAPIVIGSS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]