Click here to switch to the map view.

The map label for this gene is afsR [H]

Identifier: 158337795

GI number: 158337795

Start: 4711669

End: 4713543

Strand: Direct

Name: afsR [H]

Synonym: AM1_4679

Alternate gene names: 158337795

Gene position: 4711669-4713543 (Clockwise)

Preceding gene: 158337794

Following gene: 158337796

Centisome position: 72.45

GC content: 37.87

Gene sequence:

>1875_bases
ATGGGTGGAATCGGGAAAACAGAGCTTGTCCTCCAGTACGCGATCTCCTGTTTTAACCAACAACTCTATCCTGGGGGTGT
TTGTTGGCTTCGGGCGAGAGATCAAGAAATTGCTACTCAAATTATCAGCTTTGCCAAGGCTAATCTGGGCATCAAACCAC
CCGATAAACTAGAAACTAAGGAGAAAGTGAAATTCATATGGCAACGATGGCCAGAAGGAGATAGCCTCGTTATTGTGGAT
GATGTCACAGACTATGCTGCTATCGATCCCTATCTACCACCTGCCTCACAGAAATTCAAGATCCTGATTACCACACGCAT
CAATCTCGGTTCATCAGTTACTCAAATAGAGATTGAAAAACTCACTGATCAGGCTGCAATTAAAGTACTAAAAGCCATTG
TGGGGAAGGATCGAATAGAGTCACAGCTCACTTCTGTGAAAACTCTTTGTCAAAAAGTCGGTAATCTACCCCTAGGTTTA
GAATTATTGGGACGGTTTCTAGCAAGGAAATTAGATTGGTCTGTTCAAAAGCTGATTGAAAGACTTGAATCCAAGAAATT
AGAAGCGAAAGCCCTCATTGAAACAGAATCAGGAATGACAGCCCGGTTAGGGATTGCCGCTGCGCTGGAATTGAGTTGGG
TAGAGCTAAACGACGCAGAACAGAAACTTGCTTGCTTATTGGGGATGTTTTCTGTCGCTCCCATCTCTTGGCATTTAGTT
GAGATGAGTTTATCTAAAAAGGATACGGATTGCCTTGAAGAACTCAGAGATGAGGGGTTAATCGACAATAGCTTGCTGAA
ACGAGTAGGACAAGGCACCTATCAACTCCATCAAATTATTCAGGAATTCTTTCGAATTAAGTTGAATGAGCGCACTGATA
AGGGAGAATCTCTAAAAAAAACTTATTGCAAAGTAATGATTGGTTTTACAAAGGATATTAGTGACATTCCAACGATTGAT
GAGATTGATGAGCTGAAGAAAACTATCCCACACCTTGAAGAAATGATTAATCATTGGATTAGTTATCTAGCAGACGAAGA
TTTGATCTGGGCATTTGAAGGTATCGGTCGATTTTATGAAGGGCAGGGAGATTTTAGTCTGTCATTATTCTGGAGAAGAA
AAGGCGTAAATCAAACTCAGAAAAAATTAAGTGCTAAGAACCCTGATTATTTACGTAGTCTCAGGCATCTAGGATTGTTT
TACTTAAAACTGGGTAATGACAAGGAAGCACAACCGCTTTTAGAGAAGGTATTTGAAGAGATAAAAGACTCTGAAGAAGA
AGGTGTCTTAGGTATAAGATTACGCAACGATCTAGGAGCACTTTACTTTAGGCAGGAACGGTTTTCAAAAGCTGAATCAT
TCTATAATAAGGCACTTGAATTAAGTCAAAAGTCATTATTTAAAGAAAATTCTGATATAGCATCAATCCTCAACAACCTT
GCAAAAATCCATGAGAAAAAAGGTCTTTCTGAAAAAGCAAAATCTTTATATGATGAAGCTCTAAACCTAGAAGAAATTGG
AGATTTTAATTTCGCACAGATCCTCGATAACTTAGGTAATCACTATAATATGAAAAAACAGTATCGAGAGGCAGAACCTT
ACTTTGAAAAATCTTTAAAAATAAGAAAGAGTACCTTAGGAGAGAAACATCTTAAAGTTGCTGAGAGTCTTAGTAACACT
GCTGATAACTATTTTTTTCAAGGACGTTTTCAGGAGGCGGCAAAACTTTTTAAGCAATCGGCAGCTATTTATGAGGAGTT
ATTTGATTGCGAATATCACAAAACAGTTGAAGTTAAAAAAAGCTTAGAAATTTGCGATCTAGCGATAAGATTTTGGTTGA
TTCGACTAATAATTAAATTGAGATTATGTTTTTAA

Upstream 100 bases:

>100_bases
TAGTGGTGTGATTGCTTTCGAGGGTCGGGAGGATCTGCTTACTCAACTCCAAAGCCAGCTCAAGAACAATGAGCTAAGTG
GTATCACTGGAGTCAGAGGC

Downstream 100 bases:

>100_bases
GGTTGTGAAGAATGTCTATTTTTGTAGACTTCAAATTATGAGTAATTATCTAACATGAATAGCTAGTAAACCTGAAAGTC
ATTCTGGTGGGGGATATTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MGGIGKTELVLQYAISCFNQQLYPGGVCWLRARDQEIATQIISFAKANLGIKPPDKLETKEKVKFIWQRWPEGDSLVIVD
DVTDYAAIDPYLPPASQKFKILITTRINLGSSVTQIEIEKLTDQAAIKVLKAIVGKDRIESQLTSVKTLCQKVGNLPLGL
ELLGRFLARKLDWSVQKLIERLESKKLEAKALIETESGMTARLGIAAALELSWVELNDAEQKLACLLGMFSVAPISWHLV
EMSLSKKDTDCLEELRDEGLIDNSLLKRVGQGTYQLHQIIQEFFRIKLNERTDKGESLKKTYCKVMIGFTKDISDIPTID
EIDELKKTIPHLEEMINHWISYLADEDLIWAFEGIGRFYEGQGDFSLSLFWRRKGVNQTQKKLSAKNPDYLRSLRHLGLF
YLKLGNDKEAQPLLEKVFEEIKDSEEEGVLGIRLRNDLGALYFRQERFSKAESFYNKALELSQKSLFKENSDIASILNNL
AKIHEKKGLSEKAKSLYDEALNLEEIGDFNFAQILDNLGNHYNMKKQYREAEPYFEKSLKIRKSTLGEKHLKVAESLSNT
ADNYFFQGRFQEAAKLFKQSAAIYEELFDCEYHKTVEVKKSLEICDLAIRFWLIRLIIKLRLCF

Sequences:

>Translated_624_residues
MGGIGKTELVLQYAISCFNQQLYPGGVCWLRARDQEIATQIISFAKANLGIKPPDKLETKEKVKFIWQRWPEGDSLVIVD
DVTDYAAIDPYLPPASQKFKILITTRINLGSSVTQIEIEKLTDQAAIKVLKAIVGKDRIESQLTSVKTLCQKVGNLPLGL
ELLGRFLARKLDWSVQKLIERLESKKLEAKALIETESGMTARLGIAAALELSWVELNDAEQKLACLLGMFSVAPISWHLV
EMSLSKKDTDCLEELRDEGLIDNSLLKRVGQGTYQLHQIIQEFFRIKLNERTDKGESLKKTYCKVMIGFTKDISDIPTID
EIDELKKTIPHLEEMINHWISYLADEDLIWAFEGIGRFYEGQGDFSLSLFWRRKGVNQTQKKLSAKNPDYLRSLRHLGLF
YLKLGNDKEAQPLLEKVFEEIKDSEEEGVLGIRLRNDLGALYFRQERFSKAESFYNKALELSQKSLFKENSDIASILNNL
AKIHEKKGLSEKAKSLYDEALNLEEIGDFNFAQILDNLGNHYNMKKQYREAEPYFEKSLKIRKSTLGEKHLKVAESLSNT
ADNYFFQGRFQEAAKLFKQSAAIYEELFDCEYHKTVEVKKSLEICDLAIRFWLIRLIIKLRLCF
>Mature_623_residues
GGIGKTELVLQYAISCFNQQLYPGGVCWLRARDQEIATQIISFAKANLGIKPPDKLETKEKVKFIWQRWPEGDSLVIVDD
VTDYAAIDPYLPPASQKFKILITTRINLGSSVTQIEIEKLTDQAAIKVLKAIVGKDRIESQLTSVKTLCQKVGNLPLGLE
LLGRFLARKLDWSVQKLIERLESKKLEAKALIETESGMTARLGIAAALELSWVELNDAEQKLACLLGMFSVAPISWHLVE
MSLSKKDTDCLEELRDEGLIDNSLLKRVGQGTYQLHQIIQEFFRIKLNERTDKGESLKKTYCKVMIGFTKDISDIPTIDE
IDELKKTIPHLEEMINHWISYLADEDLIWAFEGIGRFYEGQGDFSLSLFWRRKGVNQTQKKLSAKNPDYLRSLRHLGLFY
LKLGNDKEAQPLLEKVFEEIKDSEEEGVLGIRLRNDLGALYFRQERFSKAESFYNKALELSQKSLFKENSDIASILNNLA
KIHEKKGLSEKAKSLYDEALNLEEIGDFNFAQILDNLGNHYNMKKQYREAEPYFEKSLKIRKSTLGEKHLKVAESLSNTA
DNYFFQGRFQEAAKLFKQSAAIYEELFDCEYHKTVEVKKSLEICDLAIRFWLIRLIIKLRLCF

Specific function: Global regulatory protein for secondary metabolite formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI34304360, Length=224, Percent_Identity=30.3571428571429, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI33620730, Length=197, Percent_Identity=30.9644670050761, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI110735431, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI198041728, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI198041734, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI198041731, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI12383062, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI194306559, Length=197, Percent_Identity=30.9644670050761, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI41871960, Length=197, Percent_Identity=28.4263959390863, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI41871955, Length=197, Percent_Identity=28.4263959390863, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI41871946, Length=197, Percent_Identity=28.4263959390863, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI91825557, Length=175, Percent_Identity=30.2857142857143, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984535, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71984527, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71984517, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71984524, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541458, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647555, Length=197, Percent_Identity=31.4720812182741, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005158
- InterPro:   IPR000767
- InterPro:   IPR002182
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03704 BTAD; PF00931 NB-ARC; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 71586; Mature: 71455

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGIGKTELVLQYAISCFNQQLYPGGVCWLRARDQEIATQIISFAKANLGIKPPDKLETK
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHCCHH
EKVKFIWQRWPEGDSLVIVDDVTDYAAIDPYLPPASQKFKILITTRINLGSSVTQIEIEK
HHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHH
LTDQAAIKVLKAIVGKDRIESQLTSVKTLCQKVGNLPLGLELLGRFLARKLDWSVQKLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHH
RLESKKLEAKALIETESGMTARLGIAAALELSWVELNDAEQKLACLLGMFSVAPISWHLV
HHHHCCCHHHHHEECCCCCEEHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHE
EMSLSKKDTDCLEELRDEGLIDNSLLKRVGQGTYQLHQIIQEFFRIKLNERTDKGESLKK
EHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TYCKVMIGFTKDISDIPTIDEIDELKKTIPHLEEMINHWISYLADEDLIWAFEGIGRFYE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GQGDFSLSLFWRRKGVNQTQKKLSAKNPDYLRSLRHLGLFYLKLGNDKEAQPLLEKVFEE
CCCCEEEEEEHHHCCCCHHHHHHCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IKDSEEEGVLGIRLRNDLGALYFRQERFSKAESFYNKALELSQKSLFKENSDIASILNNL
HCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKIHEKKGLSEKAKSLYDEALNLEEIGDFNFAQILDNLGNHYNMKKQYREAEPYFEKSLK
HHHHHHCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
IRKSTLGEKHLKVAESLSNTADNYFFQGRFQEAAKLFKQSAAIYEELFDCEYHKTVEVKK
HHHHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SLEICDLAIRFWLIRLIIKLRLCF
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GGIGKTELVLQYAISCFNQQLYPGGVCWLRARDQEIATQIISFAKANLGIKPPDKLETK
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHCCHH
EKVKFIWQRWPEGDSLVIVDDVTDYAAIDPYLPPASQKFKILITTRINLGSSVTQIEIEK
HHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHH
LTDQAAIKVLKAIVGKDRIESQLTSVKTLCQKVGNLPLGLELLGRFLARKLDWSVQKLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHH
RLESKKLEAKALIETESGMTARLGIAAALELSWVELNDAEQKLACLLGMFSVAPISWHLV
HHHHCCCHHHHHEECCCCCEEHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHE
EMSLSKKDTDCLEELRDEGLIDNSLLKRVGQGTYQLHQIIQEFFRIKLNERTDKGESLKK
EHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TYCKVMIGFTKDISDIPTIDEIDELKKTIPHLEEMINHWISYLADEDLIWAFEGIGRFYE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GQGDFSLSLFWRRKGVNQTQKKLSAKNPDYLRSLRHLGLFYLKLGNDKEAQPLLEKVFEE
CCCCEEEEEEHHHCCCCHHHHHHCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IKDSEEEGVLGIRLRNDLGALYFRQERFSKAESFYNKALELSQKSLFKENSDIASILNNL
HCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKIHEKKGLSEKAKSLYDEALNLEEIGDFNFAQILDNLGNHYNMKKQYREAEPYFEKSLK
HHHHHHCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
IRKSTLGEKHLKVAESLSNTADNYFFQGRFQEAAKLFKQSAAIYEELFDCEYHKTVEVKK
HHHHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SLEICDLAIRFWLIRLIIKLRLCF
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2253887; 12000953; 2428809 [H]