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The map label for this gene is cobM [H]

Identifier: 158337698

GI number: 158337698

Start: 4618134

End: 4618952

Strand: Direct

Name: cobM [H]

Synonym: AM1_4582

Alternate gene names: 158337698

Gene position: 4618134-4618952 (Clockwise)

Preceding gene: 158337697

Following gene: 158337699

Centisome position: 71.01

GC content: 49.08

Gene sequence:

>819_bases
ATGACTCCCCCTTCTCCTGAGCTACTCGAACAGACAACTTTCAGCAAATCCCTATTGCCAGCGGTTTATATCGTAGGAGC
GGGGCCAGGAGATCCTGATTTACTCACCGTTAAAGCTCAGCGTATTATCCAACAGGCAGATGTCGTCGTTTATGCCAATT
CTCTGGTGCCGAAGGAAATGTTGAGTCTCTGCCATAATGGGGCAGAATTGATTCCGACTGCGACCAAGACCCTTGAAGAT
ATCGTACCGATGATGATTGATAGGGTGCGATCGCATCTTTCAGTCGTGCGGCTACACTCTGGTGACCCCTGCCTGTATGG
GGCTGTACATGAACAAATCCAGGCTTTGGCAGAAGCCGAAATCCCCTTCGAAATTATTCCTGGTATTAGTGCATTTCAGC
TGGCTGCAGCTAAATTGCAGGTGGAACTAACGGTACCCGAACTAGTACAGACGATTATTTTGACGCGAATTAGCGGCCGA
ACACAGGTTCCAGAAGCAGAGGAACTCGCTAGCTTAGCAGCCCACAAGGCCAGCTTGTGTTTGTATCTCAGTGCGCGCCA
TGTCGATCAGGCCCAACAAAAATTACTCGCTCATTATGAGCCAGATACTCCTGTGGCCATCGGCTTTCGTTTAGGATGGC
CGGATGAGCAAATGTGGGTTGTGCCGTTATCTGAGATGGCAAAGGCGACCGAAGACCATGAGTTAATTCGGACAACCCTC
TACTTAATCAGTCCAGCTTTGAAGTCAACGCATTCTCAAGCGAGATCGCGTCTATATCACCCTGAACATCGACATTTATT
TCGGCCAGGGAAACATTGA

Upstream 100 bases:

>100_bases
TGTATTTGCTGAAGCGGAGCCTGCCTGATACAAAGCAGGCATCTTAATGCGATACTGCGGCTCTGTTTTTTTATTGATAT
TTAAGTTGAATTGAACTCCT

Downstream 100 bases:

>100_bases
AATTCATGAGTTAACAGACCTTAGCAGTAACTAATATCTGGAACACTAGGAAACGCTTGCTAGATCGGTGTGCAGAGAGC
ATAACAGTATTATTTTGCTT

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTPPSPELLEQTTFSKSLLPAVYIVGAGPGDPDLLTVKAQRIIQQADVVVYANSLVPKEMLSLCHNGAELIPTATKTLED
IVPMMIDRVRSHLSVVRLHSGDPCLYGAVHEQIQALAEAEIPFEIIPGISAFQLAAAKLQVELTVPELVQTIILTRISGR
TQVPEAEELASLAAHKASLCLYLSARHVDQAQQKLLAHYEPDTPVAIGFRLGWPDEQMWVVPLSEMAKATEDHELIRTTL
YLISPALKSTHSQARSRLYHPEHRHLFRPGKH

Sequences:

>Translated_272_residues
MTPPSPELLEQTTFSKSLLPAVYIVGAGPGDPDLLTVKAQRIIQQADVVVYANSLVPKEMLSLCHNGAELIPTATKTLED
IVPMMIDRVRSHLSVVRLHSGDPCLYGAVHEQIQALAEAEIPFEIIPGISAFQLAAAKLQVELTVPELVQTIILTRISGR
TQVPEAEELASLAAHKASLCLYLSARHVDQAQQKLLAHYEPDTPVAIGFRLGWPDEQMWVVPLSEMAKATEDHELIRTTL
YLISPALKSTHSQARSRLYHPEHRHLFRPGKH
>Mature_271_residues
TPPSPELLEQTTFSKSLLPAVYIVGAGPGDPDLLTVKAQRIIQQADVVVYANSLVPKEMLSLCHNGAELIPTATKTLEDI
VPMMIDRVRSHLSVVRLHSGDPCLYGAVHEQIQALAEAEIPFEIIPGISAFQLAAAKLQVELTVPELVQTIILTRISGRT
QVPEAEELASLAAHKASLCLYLSARHVDQAQQKLLAHYEPDTPVAIGFRLGWPDEQMWVVPLSEMAKATEDHELIRTTLY
LISPALKSTHSQARSRLYHPEHRHLFRPGKH

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:
GO:0006779: Precorrin-4 C11-methyltransferase
GO:0008152: Precorrin-4 C11-methyltransferase
GO:0008168: Precorrin-4 C11-methyltransferase
GO:0009236: Precorrin-4 C11-methyltransferase
GO:0016740: Precorrin-4 C11-methyltransferase
GO:0032259: Precorrin-4 C11-methyltransferase
GO:0043115: Precorrin-4 C11-methyltransferase
GO:0046026: Precorrin-4 C11-methyltransferase
GO:0055114: Precorrin-4 C11-methyltransferase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=193, Percent_Identity=35.2331606217617, Blast_Score=107, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6322922, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 30053; Mature: 29922

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPSPELLEQTTFSKSLLPAVYIVGAGPGDPDLLTVKAQRIIQQADVVVYANSLVPKEM
CCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEHHHHHHHHHCCEEEEECCCCHHHH
LSLCHNGAELIPTATKTLEDIVPMMIDRVRSHLSVVRLHSGDPCLYGAVHEQIQALAEAE
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHCC
IPFEIIPGISAFQLAAAKLQVELTVPELVQTIILTRISGRTQVPEAEELASLAAHKASLC
CCHHHCCCCHHHHHHHHHEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHE
LYLSARHVDQAQQKLLAHYEPDTPVAIGFRLGWPDEQMWVVPLSEMAKATEDHELIRTTL
EEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHH
YLISPALKSTHSQARSRLYHPEHRHLFRPGKH
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure 
TPPSPELLEQTTFSKSLLPAVYIVGAGPGDPDLLTVKAQRIIQQADVVVYANSLVPKEM
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEHHHHHHHHHCCEEEEECCCCHHHH
LSLCHNGAELIPTATKTLEDIVPMMIDRVRSHLSVVRLHSGDPCLYGAVHEQIQALAEAE
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHCC
IPFEIIPGISAFQLAAAKLQVELTVPELVQTIILTRISGRTQVPEAEELASLAAHKASLC
CCHHHCCCCHHHHHHHHHEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHE
LYLSARHVDQAQQKLLAHYEPDTPVAIGFRLGWPDEQMWVVPLSEMAKATEDHELIRTTL
EEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHH
YLISPALKSTHSQARSRLYHPEHRHLFRPGKH
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]