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The map label for this gene is nrdR

Identifier: 158337673

GI number: 158337673

Start: 4590681

End: 4591211

Strand: Reverse

Name: nrdR

Synonym: AM1_4556

Alternate gene names: 158337673

Gene position: 4591211-4590681 (Counterclockwise)

Preceding gene: 158337674

Following gene: 158337672

Centisome position: 70.59

GC content: 49.34

Gene sequence:

>531_bases
ATGCAATGCCCTTTTTGCCAGCATACCGATAGCCGAGTTTTAGAATCGCGCTCAGCAGAAGCGGGACAGAGTGTGCGCCG
CCGTCGGGAATGTCTGCAATGTAATCGCCGATTTACAACCTATGAGCGGATTGAGTTTGTACCGATCACCGTGATCAAAC
GCAATCAGGATAGGGAGCTTTTTGATCGTTCCAAGTTGCTCAAGGGAGTCGCAACCGCTTGTGAGAAAACAGGACTGACT
GCATTGCAGTTAGAGTCTTTGGTGGATGATGTTGAAGCGGAACTTCAGCAGCAAGCTGTGAGAGAGGTGACGAGTACAGA
GCTCGGTGAATCTGTTTTGACAAAGCTACAATCCCTCAGTGAAGTAGCTTATGTCAGGTTTGCATCTGTCTATCGACAGT
TCCGGGGAATTCGAGATTTTGTAGAGGCCCTTGATCAGCTTAAAGAGTCTGGGGACGGTCCTTTGCCAAGTGTGCTGGAC
GAACCCTACGAAGATACGGCACAGCCTACCATTATGATTTCTCCCCAGTGA

Upstream 100 bases:

>100_bases
ATCACAGTGATTTAAAAAACGCTACAGATTGGGAACATCGATCTTACAATCGTTTTTCTGGAATTAGAACTACTCTGTTA
CCCCCTTTGAACAAGCCAGT

Downstream 100 bases:

>100_bases
ATATCAGTCATTTAATATCAGTTATTAACTTGAACTGTTAGCATCTTCATCGTCAGACCACCAACAAAAAAATATATAGT
TAAGGTTTCGGATATTGCGC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MQCPFCQHTDSRVLESRSAEAGQSVRRRRECLQCNRRFTTYERIEFVPITVIKRNQDRELFDRSKLLKGVATACEKTGLT
ALQLESLVDDVEAELQQQAVREVTSTELGESVLTKLQSLSEVAYVRFASVYRQFRGIRDFVEALDQLKESGDGPLPSVLD
EPYEDTAQPTIMISPQ

Sequences:

>Translated_176_residues
MQCPFCQHTDSRVLESRSAEAGQSVRRRRECLQCNRRFTTYERIEFVPITVIKRNQDRELFDRSKLLKGVATACEKTGLT
ALQLESLVDDVEAELQQQAVREVTSTELGESVLTKLQSLSEVAYVRFASVYRQFRGIRDFVEALDQLKESGDGPLPSVLD
EPYEDTAQPTIMISPQ
>Mature_176_residues
MQCPFCQHTDSRVLESRSAEAGQSVRRRRECLQCNRRFTTYERIEFVPITVIKRNQDRELFDRSKLLKGVATACEKTGLT
ALQLESLVDDVEAELQQQAVREVTSTELGESVLTKLQSLSEVAYVRFASVYRQFRGIRDFVEALDQLKESGDGPLPSVLD
EPYEDTAQPTIMISPQ

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=42.9530201342282, Blast_Score=127, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACAM1 (B0BZ87)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001518849.1
- GeneID:   5683358
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4556
- HOGENOM:   HBG351755
- OMA:   RRRRECK
- ProtClustDB:   PRK00464
- BioCyc:   AMAR329726:AM1_4556-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 20034; Mature: 20034

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCPFCQHTDSRVLESRSAEAGQSVRRRRECLQCNRRFTTYERIEFVPITVIKRNQDREL
CCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEHEEEECCCCHHH
FDRSKLLKGVATACEKTGLTALQLESLVDDVEAELQQQAVREVTSTELGESVLTKLQSLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFRGIRDFVEALDQLKESGDGPLPSVLDEPYEDTAQPTIMISPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCCCEEEECCC
>Mature Secondary Structure
MQCPFCQHTDSRVLESRSAEAGQSVRRRRECLQCNRRFTTYERIEFVPITVIKRNQDREL
CCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEHEEEECCCCHHH
FDRSKLLKGVATACEKTGLTALQLESLVDDVEAELQQQAVREVTSTELGESVLTKLQSLS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFRGIRDFVEALDQLKESGDGPLPSVLDEPYEDTAQPTIMISPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA