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The map label for this gene is rep [C]

Identifier: 158337497

GI number: 158337497

Start: 4406189

End: 4408486

Strand: Reverse

Name: rep [C]

Synonym: AM1_4376

Alternate gene names: 158337497

Gene position: 4408486-4406189 (Counterclockwise)

Preceding gene: 158337498

Following gene: 158337496

Centisome position: 67.78

GC content: 51.17

Gene sequence:

>2298_bases
TTGGCAACCAATTTAGAGCGAAAATTAGCTGAATTACGGGCATCTCTCAGGCCTGGCCAGCAAGAATTAGCAGATTGGCA
AGCTGGTCCGCTAGCTGTTTCTGCTGTACCGGGTGCAGGGAAATCCTATGGTATGGCGGTGGCTGCGGCGATCACCCTAG
GGCGTCAAAATCTAAATCGTGCCCAACAGCTGGTGATTGTCACGTTCACTCGCTCAGCGGCGACACATCTCAAACAGCAG
GTCCGAAAACATTTACGCGAGCTACAGCTCCCCTTAGGTGGGTTTACCGTGCAAACCTTACATGGGTTAGCCCTCAATAT
TGCTTCCCGTCATCCCCAACTTTCGGGGATTCATTTAGACCAAGTCACCCTGATTACCCCCAACCGGCACCATCGCCTCT
TGCGCCACTGTGTTGAACAATGGGTGGCAGATCATCCTCAAATGTACCAAGAGCTCCTGGTTCGAGGAGCTTTTGATGGG
GAAGAAACGGAGCGGTTACGTCGGCAGTCAGTGTTGAGATCGGATTGTTTGCCGGAATTAGCTGCGATCGCAATTCGCGA
AGCCAAAAGTTCGGGACTCAGCCCTCAGCAGCTCTATGCTTTGGCCGAACAGGTGCAAGATGAGGTATCGGTACTTGCGA
TCGCAGCTGGTCTTTACGAACGATACCAACAACTACTCCAAGCTCAACAGCTCATTGATTATGACGATATGATCCTAGCG
GCTCTGCAGGTGCTCGATAACCAGAGCGCTCGCCAAGTCTGGCAAAAACAGGTCTTTGCCGTTTTCGAAGACGAAGCCCA
GGATTCAACCCCACTCCAGTTCCGTTTACTGAACAGATTAGCTAGTCACGAGGTCTCCAAAGCAAAACCCAATCTAGTCC
GCGTTGGCGATCCCAACCAAGCCATCAACTCTACCTTTACCCCTGCCGACCCCATTTTCTTCCGAGAATTTTGCCAACAG
AGCCAAGCTCAACAGCGATTAGCAACCATGAATCAGGCCGGACGCAGCTCTACCATCATCATTCAGGCTGCTAATTTTAT
GCTGGACTGGATCAATCAGTCTCAATTAGCAGGACAAGAACAACCCTTTCAACCTCAGACGATTCAAACGGTAGCCAAGC
ACGATCCTCAAGCCAACGCAAATCCAGCCCATGAAGGACGAGGACTAGAGATATACACACCAGAAGATGTTTACCAAACG
GCTGATCTCATCGGCCAGCGGGTCTGCCAACTGCTGACGGATCATCCAGACGCCAATGCAGCCATCCTAGTCCGGGAAAA
TAAACAAGGGAGCTTTCTAGCAGAGCGCCTCAATCACCCGGATCAAACGGTGACTCTAGCCGCTCATGGCATTGACATCC
TCGATGTGGGAGGTGGCAGCCGCCAGACGCAAGTTCCCTTTGAAATGCTGACCATTTTGCAGTTTTTAGCCCGTCCCCAT
TCTCCCAAAACCCTCAAAGCAGCCCTGCAAATTTTGGTCGATCGGCAACTCATCCCAGCCCAAGAGGTCCATCCTTTAGC
CAGTCAACCTGAAATTTTCCTCTATCCAGGCCCGCTAGAGCCACCCCAGTCGGAGCAGGTGCAGGAAGCCCGTAGTTTTT
GCTGCAAGCTGTTGCGATCACGATGGGAATTACCTCACTATCGACTGATTTCTTTTTTAGCCTTATCCCTGAAATACAAT
GCCGCCGAGCTAGCCACTGCCGATAAATTAGCAGCACGACTCTCTCAACAAGTTCAGGGGGCACCGTCGATGACAACGAC
CTTACCCATTTTGCAAGAGCTAATCAGTGCCGAACGGTTTGATCCCGTTGACGTTGAAGATGTTGAGTCCCAGTATTTAC
GTCCACGCCAACTCACGATCATTACCATGCACAAAGCCAAGGGGCTGGATTGGGATTTTGTATTTCTGCCGTTTCTACAT
GCCCGTATTATTCCAGGGGAATTAAGAATTCCTGCAGCTAGCCAATTCCTTGGCCCCTTCAGTTTGGCAGAAGTGGCTCG
GGCTCAAATCCGAGCTAATGTCCATAACCAAGTCCCATTACCAAATGTAGAAGAGGCGTGGCAACGGGCTAGCGATCTCA
AAAGTGCAGAAGAATTTCGTCTCCTCTATGTCGCGATGACCCGGGCTAAACGACTGTTGTGGATGTCTGCAGCCAAACAA
GCCCCCTACAATTGGAACTGGTTTGACTGGCAACGCCAAACGAAGCTGGATAAGCAGCCTCCTTGTCCTGTCCTGAGGCC
CTTACAGGCTCAATTCCAATCCGATCAAGCCCCTAACTCAACGCCGTCCAGGGTTTGA

Upstream 100 bases:

>100_bases
GACAGTCGCCACCACTTAAAAGGTCTCCCGTTGCCCAGGCTATTGCTGGTCGAGTCAGAGTAGATTGATATACTACGCTC
ACACCGCAATTGATAACCTC

Downstream 100 bases:

>100_bases
ACTCCACCTATGCTGAATCAAATGCTGCTTCTACAGACAGCATAAATGAGGATCGTTTTTCTTCTTATACTTCTTTGTAA
TACATTGAAGCATAGAAGCC

Product: UvrD/REP helicase

Products: NA

Alternate protein names: ATP-Dependent DNA Helicase; ATP-Dependent DNA Helicase Rep; ATP-Dependent DNA Helicase PcrA; UvrD/REP Helicase Domain-Containing Protein; Helicase; DNA Helicase; ATP-Dependent DNA Helicase Protein; ATP-Dependent Helicase; UvrD/Rep Family Helicase; UvrD/REP Helicase Subfamily; DNA Helicase And Single-Stranded DNA-Dependent ATPase; UvrD/REP Helicase Domain Protein; ATP-Dependent DNA Helicase II PcrA; DNA Helicase II; Superfamily I DNA/RNA Helicase

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MATNLERKLAELRASLRPGQQELADWQAGPLAVSAVPGAGKSYGMAVAAAITLGRQNLNRAQQLVIVTFTRSAATHLKQQ
VRKHLRELQLPLGGFTVQTLHGLALNIASRHPQLSGIHLDQVTLITPNRHHRLLRHCVEQWVADHPQMYQELLVRGAFDG
EETERLRRQSVLRSDCLPELAAIAIREAKSSGLSPQQLYALAEQVQDEVSVLAIAAGLYERYQQLLQAQQLIDYDDMILA
ALQVLDNQSARQVWQKQVFAVFEDEAQDSTPLQFRLLNRLASHEVSKAKPNLVRVGDPNQAINSTFTPADPIFFREFCQQ
SQAQQRLATMNQAGRSSTIIIQAANFMLDWINQSQLAGQEQPFQPQTIQTVAKHDPQANANPAHEGRGLEIYTPEDVYQT
ADLIGQRVCQLLTDHPDANAAILVRENKQGSFLAERLNHPDQTVTLAAHGIDILDVGGGSRQTQVPFEMLTILQFLARPH
SPKTLKAALQILVDRQLIPAQEVHPLASQPEIFLYPGPLEPPQSEQVQEARSFCCKLLRSRWELPHYRLISFLALSLKYN
AAELATADKLAARLSQQVQGAPSMTTTLPILQELISAERFDPVDVEDVESQYLRPRQLTIITMHKAKGLDWDFVFLPFLH
ARIIPGELRIPAASQFLGPFSLAEVARAQIRANVHNQVPLPNVEEAWQRASDLKSAEEFRLLYVAMTRAKRLLWMSAAKQ
APYNWNWFDWQRQTKLDKQPPCPVLRPLQAQFQSDQAPNSTPSRV

Sequences:

>Translated_765_residues
MATNLERKLAELRASLRPGQQELADWQAGPLAVSAVPGAGKSYGMAVAAAITLGRQNLNRAQQLVIVTFTRSAATHLKQQ
VRKHLRELQLPLGGFTVQTLHGLALNIASRHPQLSGIHLDQVTLITPNRHHRLLRHCVEQWVADHPQMYQELLVRGAFDG
EETERLRRQSVLRSDCLPELAAIAIREAKSSGLSPQQLYALAEQVQDEVSVLAIAAGLYERYQQLLQAQQLIDYDDMILA
ALQVLDNQSARQVWQKQVFAVFEDEAQDSTPLQFRLLNRLASHEVSKAKPNLVRVGDPNQAINSTFTPADPIFFREFCQQ
SQAQQRLATMNQAGRSSTIIIQAANFMLDWINQSQLAGQEQPFQPQTIQTVAKHDPQANANPAHEGRGLEIYTPEDVYQT
ADLIGQRVCQLLTDHPDANAAILVRENKQGSFLAERLNHPDQTVTLAAHGIDILDVGGGSRQTQVPFEMLTILQFLARPH
SPKTLKAALQILVDRQLIPAQEVHPLASQPEIFLYPGPLEPPQSEQVQEARSFCCKLLRSRWELPHYRLISFLALSLKYN
AAELATADKLAARLSQQVQGAPSMTTTLPILQELISAERFDPVDVEDVESQYLRPRQLTIITMHKAKGLDWDFVFLPFLH
ARIIPGELRIPAASQFLGPFSLAEVARAQIRANVHNQVPLPNVEEAWQRASDLKSAEEFRLLYVAMTRAKRLLWMSAAKQ
APYNWNWFDWQRQTKLDKQPPCPVLRPLQAQFQSDQAPNSTPSRV
>Mature_764_residues
ATNLERKLAELRASLRPGQQELADWQAGPLAVSAVPGAGKSYGMAVAAAITLGRQNLNRAQQLVIVTFTRSAATHLKQQV
RKHLRELQLPLGGFTVQTLHGLALNIASRHPQLSGIHLDQVTLITPNRHHRLLRHCVEQWVADHPQMYQELLVRGAFDGE
ETERLRRQSVLRSDCLPELAAIAIREAKSSGLSPQQLYALAEQVQDEVSVLAIAAGLYERYQQLLQAQQLIDYDDMILAA
LQVLDNQSARQVWQKQVFAVFEDEAQDSTPLQFRLLNRLASHEVSKAKPNLVRVGDPNQAINSTFTPADPIFFREFCQQS
QAQQRLATMNQAGRSSTIIIQAANFMLDWINQSQLAGQEQPFQPQTIQTVAKHDPQANANPAHEGRGLEIYTPEDVYQTA
DLIGQRVCQLLTDHPDANAAILVRENKQGSFLAERLNHPDQTVTLAAHGIDILDVGGGSRQTQVPFEMLTILQFLARPHS
PKTLKAALQILVDRQLIPAQEVHPLASQPEIFLYPGPLEPPQSEQVQEARSFCCKLLRSRWELPHYRLISFLALSLKYNA
AELATADKLAARLSQQVQGAPSMTTTLPILQELISAERFDPVDVEDVESQYLRPRQLTIITMHKAKGLDWDFVFLPFLHA
RIIPGELRIPAASQFLGPFSLAEVARAQIRANVHNQVPLPNVEEAWQRASDLKSAEEFRLLYVAMTRAKRLLWMSAAKQA
PYNWNWFDWQRQTKLDKQPPCPVLRPLQAQFQSDQAPNSTPSRV

Specific function: Rep Helicase Is A Single-Stranded DNA-Dependent ATPase Involved In DNA Replication; It Can Initiate Unwinding At A Nick In The DNA. It Binds To The Single-Stranded DNA And Acts In A Progressive Fashion Along The DNA In The 3' To 5' Direction. [C]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 85885; Mature: 85754

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNLERKLAELRASLRPGQQELADWQAGPLAVSAVPGAGKSYGMAVAAAITLGRQNLNR
CCCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AQQLVIVTFTRSAATHLKQQVRKHLRELQLPLGGFTVQTLHGLALNIASRHPQLSGIHLD
HHEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEC
QVTLITPNRHHRLLRHCVEQWVADHPQMYQELLVRGAFDGEETERLRRQSVLRSDCLPEL
EEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAIAIREAKSSGLSPQQLYALAEQVQDEVSVLAIAAGLYERYQQLLQAQQLIDYDDMILA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALQVLDNQSARQVWQKQVFAVFEDEAQDSTPLQFRLLNRLASHEVSKAKPNLVRVGDPNQ
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCH
AINSTFTPADPIFFREFCQQSQAQQRLATMNQAGRSSTIIIQAANFMLDWINQSQLAGQE
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCHHHHCCCC
QPFQPQTIQTVAKHDPQANANPAHEGRGLEIYTPEDVYQTADLIGQRVCQLLTDHPDANA
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCE
AILVRENKQGSFLAERLNHPDQTVTLAAHGIDILDVGGGSRQTQVPFEMLTILQFLARPH
EEEEEECCCCHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHCCC
SPKTLKAALQILVDRQLIPAQEVHPLASQPEIFLYPGPLEPPQSEQVQEARSFCCKLLRS
CCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
RWELPHYRLISFLALSLKYNAAELATADKLAARLSQQVQGAPSMTTTLPILQELISAERF
HCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
DPVDVEDVESQYLRPRQLTIITMHKAKGLDWDFVFLPFLHARIIPGELRIPAASQFLGPF
CCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCH
SLAEVARAQIRANVHNQVPLPNVEEAWQRASDLKSAEEFRLLYVAMTRAKRLLWMSAAKQ
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHC
APYNWNWFDWQRQTKLDKQPPCPVLRPLQAQFQSDQAPNSTPSRV
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ATNLERKLAELRASLRPGQQELADWQAGPLAVSAVPGAGKSYGMAVAAAITLGRQNLNR
CCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AQQLVIVTFTRSAATHLKQQVRKHLRELQLPLGGFTVQTLHGLALNIASRHPQLSGIHLD
HHEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEC
QVTLITPNRHHRLLRHCVEQWVADHPQMYQELLVRGAFDGEETERLRRQSVLRSDCLPEL
EEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAIAIREAKSSGLSPQQLYALAEQVQDEVSVLAIAAGLYERYQQLLQAQQLIDYDDMILA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALQVLDNQSARQVWQKQVFAVFEDEAQDSTPLQFRLLNRLASHEVSKAKPNLVRVGDPNQ
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCH
AINSTFTPADPIFFREFCQQSQAQQRLATMNQAGRSSTIIIQAANFMLDWINQSQLAGQE
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCHHHHCCCC
QPFQPQTIQTVAKHDPQANANPAHEGRGLEIYTPEDVYQTADLIGQRVCQLLTDHPDANA
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCE
AILVRENKQGSFLAERLNHPDQTVTLAAHGIDILDVGGGSRQTQVPFEMLTILQFLARPH
EEEEEECCCCHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHCCC
SPKTLKAALQILVDRQLIPAQEVHPLASQPEIFLYPGPLEPPQSEQVQEARSFCCKLLRS
CCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
RWELPHYRLISFLALSLKYNAAELATADKLAARLSQQVQGAPSMTTTLPILQELISAERF
HCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
DPVDVEDVESQYLRPRQLTIITMHKAKGLDWDFVFLPFLHARIIPGELRIPAASQFLGPF
CCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCH
SLAEVARAQIRANVHNQVPLPNVEEAWQRASDLKSAEEFRLLYVAMTRAKRLLWMSAAKQ
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHC
APYNWNWFDWQRQTKLDKQPPCPVLRPLQAQFQSDQAPNSTPSRV
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA