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The map label for this gene is livK [C]

Identifier: 158337446

GI number: 158337446

Start: 4351635

End: 4352924

Strand: Reverse

Name: livK [C]

Synonym: AM1_4325

Alternate gene names: 158337446

Gene position: 4352924-4351635 (Counterclockwise)

Preceding gene: 158337457

Following gene: 158337435

Centisome position: 66.93

GC content: 52.56

Gene sequence:

>1290_bases
ATGCTTCGTCAACGTTTAGTTTCAGGGGCAGCTTTAGGGCTTTGTTGTGCTGCCATCTCAGGATGTCAATTATCCGCCCC
TGACTCGACCGGAGACGGCCTCAAACTAGGCACGCTATTGCCGATTACCGGCGACTTGGCGCAATATGGCACACCGATGC
AAGAAACGGCCAACTTGTTAATCAAAACCGTGAATGCCTGTGATGGAGTGTTGGGGAAACCGGTCACCCTTATCAGTGCG
GATACTCAAACGGATCCCGCCCAAGGCACCCAAGCCATGACTAAACTCGTTGAGGCTGATCAGGTCGTGGGAGTGGTGGG
AGCAGCCTCTAGTGCATCATCTAGCGCGGCACTTCCCATTGCAGTTCGGGGTCAAGTTGTCCAAATCTCTCCGGCCAGTA
CCAGTCCTGTGTTTACTGAACGGGCCGAAAAAGGCGAATTTGAAGGCTTTTGGGCCCGAACGGCACCGCCTGACACCTTT
CAGAGTCAGGCCCTCGCCCAATTGGCCAAGCAGAAAGGGTACAAGTCTGTCGCTATTTTGGCCATCAATAATGACTATGG
CAATGGCTTAGTGTCTGCCTTTATCCCCGCATTTAAAGCGATGGGAGGGACGGTGGTCAATGAAACTCGGCCCACCTTCT
ATGATCCGAATACCTCCACCTTTGATACAGAAGTGAATCAGGTGTTTAAGGGCCAACCCGATGCAGTACTACTGGTTTCC
TATCCAGAAACGGGCAGTTTAATCCTCAAATCTGCTCAAGAACTCGGGTTCTTAGATGGAAACACGGCATTAATCACCAC
TGATGGCATGAAAGAGACCAGTCTTGCCGATTTAGTGGGTAAAAATGCCCAAGGGGAATATTTAGTGTCCGGGATGCTGG
GGACGGCTCCCAGTGCGGGTGGCCCTGCCTTAGTAGCCTTTCAAAAACGGTATCAAGACGCGTTTCAGCGAGAGCCCAGT
GTCTTTGACCCTAATACTTGGGATGCGACGGCCCTTCTAGTTCTGGCTGCCGAGGCCGCCAAGGAGCCCACCGGTACTGG
CATCCGAGAACAGCTACAAGCAGTCGCCAATGCCCCGGGCGAAGAAGTGACGGATGTCTGTGAAGCTTTAGCCTTATTAC
GGGAAGGGAAAACCATCAACTATCAGGGGGCCAGCGGCACCGTTGATCTAAACCCTCAAGGCGACGTCACGGGAAGCTAT
GACATTTGGAGCATTGATGACCAGGGCAAACTTCAAGTTAATGACACCATCGAAATTACAGGAGCAGACGCGGCCACTCC
TCCAGAATAG

Upstream 100 bases:

>100_bases
AGCAGGACTAGGAGAAGCGGAAGTGAGTCGACTAAGCTGGTGATTGAATTTTCTGGTCTCATCAACTCATGGTTGATATT
CGGTGCTCGGGAGGTTGGTC

Downstream 100 bases:

>100_bases
GGGTTAGCCCTCTTCCACCATAGATGTGCTGTCATCAGCAATATCTAGTTTTTCCTGCAGCTCGGTTTTGATCCGGTTCA
AAATAGTGGCCTGATCGAGG

Product: amino acid ABC transporter amino acid-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLRQRLVSGAALGLCCAAISGCQLSAPDSTGDGLKLGTLLPITGDLAQYGTPMQETANLLIKTVNACDGVLGKPVTLISA
DTQTDPAQGTQAMTKLVEADQVVGVVGAASSASSSAALPIAVRGQVVQISPASTSPVFTERAEKGEFEGFWARTAPPDTF
QSQALAQLAKQKGYKSVAILAINNDYGNGLVSAFIPAFKAMGGTVVNETRPTFYDPNTSTFDTEVNQVFKGQPDAVLLVS
YPETGSLILKSAQELGFLDGNTALITTDGMKETSLADLVGKNAQGEYLVSGMLGTAPSAGGPALVAFQKRYQDAFQREPS
VFDPNTWDATALLVLAAEAAKEPTGTGIREQLQAVANAPGEEVTDVCEALALLREGKTINYQGASGTVDLNPQGDVTGSY
DIWSIDDQGKLQVNDTIEITGADAATPPE

Sequences:

>Translated_429_residues
MLRQRLVSGAALGLCCAAISGCQLSAPDSTGDGLKLGTLLPITGDLAQYGTPMQETANLLIKTVNACDGVLGKPVTLISA
DTQTDPAQGTQAMTKLVEADQVVGVVGAASSASSSAALPIAVRGQVVQISPASTSPVFTERAEKGEFEGFWARTAPPDTF
QSQALAQLAKQKGYKSVAILAINNDYGNGLVSAFIPAFKAMGGTVVNETRPTFYDPNTSTFDTEVNQVFKGQPDAVLLVS
YPETGSLILKSAQELGFLDGNTALITTDGMKETSLADLVGKNAQGEYLVSGMLGTAPSAGGPALVAFQKRYQDAFQREPS
VFDPNTWDATALLVLAAEAAKEPTGTGIREQLQAVANAPGEEVTDVCEALALLREGKTINYQGASGTVDLNPQGDVTGSY
DIWSIDDQGKLQVNDTIEITGADAATPPE
>Mature_429_residues
MLRQRLVSGAALGLCCAAISGCQLSAPDSTGDGLKLGTLLPITGDLAQYGTPMQETANLLIKTVNACDGVLGKPVTLISA
DTQTDPAQGTQAMTKLVEADQVVGVVGAASSASSSAALPIAVRGQVVQISPASTSPVFTERAEKGEFEGFWARTAPPDTF
QSQALAQLAKQKGYKSVAILAINNDYGNGLVSAFIPAFKAMGGTVVNETRPTFYDPNTSTFDTEVNQVFKGQPDAVLLVS
YPETGSLILKSAQELGFLDGNTALITTDGMKETSLADLVGKNAQGEYLVSGMLGTAPSAGGPALVAFQKRYQDAFQREPS
VFDPNTWDATALLVLAAEAAKEPTGTGIREQLQAVANAPGEEVTDVCEALALLREGKTINYQGASGTVDLNPQGDVTGSY
DIWSIDDQGKLQVNDTIEITGADAATPPE

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Homo sapiens, GI187960069, Length=343, Percent_Identity=23.3236151603499, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI187960067, Length=343, Percent_Identity=23.3236151603499, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI32528268, Length=347, Percent_Identity=24.7838616714697, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4504147, Length=347, Percent_Identity=24.7838616714697, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789867, Length=393, Percent_Identity=26.4631043256997, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994941, Length=318, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 44571; Mature: 44571

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQRLVSGAALGLCCAAISGCQLSAPDSTGDGLKLGTLLPITGDLAQYGTPMQETANLL
CCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHH
IKTVNACDGVLGKPVTLISADTQTDPAQGTQAMTKLVEADQVVGVVGAASSASSSAALPI
HHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEE
AVRGQVVQISPASTSPVFTERAEKGEFEGFWARTAPPDTFQSQALAQLAKQKGYKSVAIL
EECCEEEEECCCCCCCHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEE
AINNDYGNGLVSAFIPAFKAMGGTVVNETRPTFYDPNTSTFDTEVNQVFKGQPDAVLLVS
EEECCCCCHHHHHHHHHHHHHCCEEEECCCCCEECCCCCCCHHHHHHHHCCCCCEEEEEE
YPETGSLILKSAQELGFLDGNTALITTDGMKETSLADLVGKNAQGEYLVSGMLGTAPSAG
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEECHHCCCCCCC
GPALVAFQKRYQDAFQREPSVFDPNTWDATALLVLAAEAAKEPTGTGIREQLQAVANAPG
CCEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
EEVTDVCEALALLREGKTINYQGASGTVDLNPQGDVTGSYDIWSIDDQGKLQVNDTIEIT
HHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCEEEEE
GADAATPPE
CCCCCCCCC
>Mature Secondary Structure
MLRQRLVSGAALGLCCAAISGCQLSAPDSTGDGLKLGTLLPITGDLAQYGTPMQETANLL
CCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHH
IKTVNACDGVLGKPVTLISADTQTDPAQGTQAMTKLVEADQVVGVVGAASSASSSAALPI
HHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEE
AVRGQVVQISPASTSPVFTERAEKGEFEGFWARTAPPDTFQSQALAQLAKQKGYKSVAIL
EECCEEEEECCCCCCCHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEE
AINNDYGNGLVSAFIPAFKAMGGTVVNETRPTFYDPNTSTFDTEVNQVFKGQPDAVLLVS
EEECCCCCHHHHHHHHHHHHHCCEEEECCCCCEECCCCCCCHHHHHHHHCCCCCEEEEEE
YPETGSLILKSAQELGFLDGNTALITTDGMKETSLADLVGKNAQGEYLVSGMLGTAPSAG
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEECHHCCCCCCC
GPALVAFQKRYQDAFQREPSVFDPNTWDATALLVLAAEAAKEPTGTGIREQLQAVANAPG
CCEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
EEVTDVCEALALLREGKTINYQGASGTVDLNPQGDVTGSYDIWSIDDQGKLQVNDTIEIT
HHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCEEECCEEEEE
GADAATPPE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]