Click here to switch to the map view.

The map label for this gene is vanW [H]

Identifier: 158337390

GI number: 158337390

Start: 4287747

End: 4288613

Strand: Reverse

Name: vanW [H]

Synonym: AM1_4269

Alternate gene names: 158337390

Gene position: 4288613-4287747 (Counterclockwise)

Preceding gene: 158337391

Following gene: 158337388

Centisome position: 65.94

GC content: 45.56

Gene sequence:

>867_bases
TTGCCTGTGAACTACCTTCAACAGCCCCAGCCTCAGCAACGCACTCGCCTGAGATTATTGCTAGGTCGACAATATTACAT
TCAAAAACGAAAGTGGGAATGGCAGTTTTCAGGGACAAAGTTTGCAGTCCCCAAAGGGGCCAATCGCTTACCGATCACAG
TATTTTCCCATCAGTCTTTTTTACTACGTCAACTTAAAGATGTAGACATGTGGCTACAGCACAACAAAGTCACTAATTTA
CAGCTAGCCATTAACTGCATCAACCCAGTCATCATTTATCCCGGAGAGGTTTTCTCCTTTTGGTATTTAGTCGGCAATCC
CACCAAACGACGCGGCTTCAAACTGGGTATGACCTTGAACAATGGCCAAGTGAAATCAGGGTATGGAGGTGGACTGTGCC
AGTTAGCCAATCTGATATATTGGATGGCTCTACATTCTCCCCTAACCATTAAAGAACGCTGGCGACACAGCTATGATGTC
TTTCCCGATCTCAATCGTTCCCTTCCCTTTGGCAGTGGGGCAACGGTCGCCTATAACTATATTGATTTACAGCTAGAAAA
CAACACTCACCAACCCTTTCAACTATGTCTCTGGTTAACGGACACAGACCTATGTGGCGAGCTGCGATCGGATACAAAAT
GTCCCTATCATTACGACGTCTTGGAGCGCAATCACCAAATTACGGGTCCTGTTGCTGGTCGATATATGCGCCACAACCAG
ATTTTTCGGAAAAAACGTCATGTATTGACCGATGAGGTTTTCCCAGATGAATTTATTACTGAGAACCACGCACTCATGAT
GTATTCACCCTTGCTAAGTAGTGGGGATGAGGAGGCGTCATCTTCTAAATCCTCAGCCCATTCCTAA

Upstream 100 bases:

>100_bases
GCCATTGTCAAAAAAGTGCTGATCTATATCTTGCTGTTAAAGATCACAGCTAACCCACCCTAGCCTTGCTATCACTAAGA
CAAGATTTCAATCGCGAAAC

Downstream 100 bases:

>100_bases
TAAGCTGGGGATACTGCAAAGACTCATATTGTATGGCTTCTGATTGGAAGACTCGTCGTCTCGCCAGAATACACAAGCGT
GTCTGTATGGCCACGCTGCC

Product: vancomycin B-type resistance protein VanW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MPVNYLQQPQPQQRTRLRLLLGRQYYIQKRKWEWQFSGTKFAVPKGANRLPITVFSHQSFLLRQLKDVDMWLQHNKVTNL
QLAINCINPVIIYPGEVFSFWYLVGNPTKRRGFKLGMTLNNGQVKSGYGGGLCQLANLIYWMALHSPLTIKERWRHSYDV
FPDLNRSLPFGSGATVAYNYIDLQLENNTHQPFQLCLWLTDTDLCGELRSDTKCPYHYDVLERNHQITGPVAGRYMRHNQ
IFRKKRHVLTDEVFPDEFITENHALMMYSPLLSSGDEEASSSKSSAHS

Sequences:

>Translated_288_residues
MPVNYLQQPQPQQRTRLRLLLGRQYYIQKRKWEWQFSGTKFAVPKGANRLPITVFSHQSFLLRQLKDVDMWLQHNKVTNL
QLAINCINPVIIYPGEVFSFWYLVGNPTKRRGFKLGMTLNNGQVKSGYGGGLCQLANLIYWMALHSPLTIKERWRHSYDV
FPDLNRSLPFGSGATVAYNYIDLQLENNTHQPFQLCLWLTDTDLCGELRSDTKCPYHYDVLERNHQITGPVAGRYMRHNQ
IFRKKRHVLTDEVFPDEFITENHALMMYSPLLSSGDEEASSSKSSAHS
>Mature_287_residues
PVNYLQQPQPQQRTRLRLLLGRQYYIQKRKWEWQFSGTKFAVPKGANRLPITVFSHQSFLLRQLKDVDMWLQHNKVTNLQ
LAINCINPVIIYPGEVFSFWYLVGNPTKRRGFKLGMTLNNGQVKSGYGGGLCQLANLIYWMALHSPLTIKERWRHSYDVF
PDLNRSLPFGSGATVAYNYIDLQLENNTHQPFQLCLWLTDTDLCGELRSDTKCPYHYDVLERNHQITGPVAGRYMRHNQI
FRKKRHVLTDEVFPDEFITENHALMMYSPLLSSGDEEASSSKSSAHS

Specific function: Unknown

COG id: COG2720

COG function: function code V; Uncharacterized vancomycin resistance protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007391 [H]

Pfam domain/function: PF04294 VanW [H]

EC number: NA

Molecular weight: Translated: 33470; Mature: 33339

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNYLQQPQPQQRTRLRLLLGRQYYIQKRKWEWQFSGTKFAVPKGANRLPITVFSHQSF
CCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCEEEEECCEEEECCCCCCCCCEEEECCHHH
LLRQLKDVDMWLQHNKVTNLQLAINCINPVIIYPGEVFSFWYLVGNPTKRRGFKLGMTLN
HHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCHHEEEEEEECCCCCCCCEEEEEEEC
NGQVKSGYGGGLCQLANLIYWMALHSPLTIKERWRHSYDVFPDLNRSLPFGSGATVAYNY
CCEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEE
IDLQLENNTHQPFQLCLWLTDTDLCGELRSDTKCPYHYDVLERNHQITGPVAGRYMRHNQ
EEEEECCCCCCCEEEEEEEECCHHHHHHHCCCCCCEEHHHHHCCCEECCCHHHHHHHHHH
IFRKKRHVLTDEVFPDEFITENHALMMYSPLLSSGDEEASSSKSSAHS
HHHHHHHHHCCCCCCHHHHCCCCEEEEEECHHCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
PVNYLQQPQPQQRTRLRLLLGRQYYIQKRKWEWQFSGTKFAVPKGANRLPITVFSHQSF
CCCCCCCCCHHHHHHHHHHHCCHHHHHCCCEEEEECCEEEECCCCCCCCCEEEECCHHH
LLRQLKDVDMWLQHNKVTNLQLAINCINPVIIYPGEVFSFWYLVGNPTKRRGFKLGMTLN
HHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCHHEEEEEEECCCCCCCCEEEEEEEC
NGQVKSGYGGGLCQLANLIYWMALHSPLTIKERWRHSYDVFPDLNRSLPFGSGATVAYNY
CCEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEE
IDLQLENNTHQPFQLCLWLTDTDLCGELRSDTKCPYHYDVLERNHQITGPVAGRYMRHNQ
EEEEECCCCCCCEEEEEEEECCHHHHHHHCCCCCCEEHHHHHCCCEECCCHHHHHHHHHH
IFRKKRHVLTDEVFPDEFITENHALMMYSPLLSSGDEEASSSKSSAHS
HHHHHHHHHCCCCCCHHHHCCCCEEEEEECHHCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]