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The map label for this gene is dspA [H]

Identifier: 158337336

GI number: 158337336

Start: 4234369

End: 4236285

Strand: Direct

Name: dspA [H]

Synonym: AM1_4214

Alternate gene names: 158337336

Gene position: 4234369-4236285 (Clockwise)

Preceding gene: 158337332

Following gene: 158337341

Centisome position: 65.11

GC content: 48.72

Gene sequence:

>1917_bases
TTGTTTGAAAGATTCAGAAAAATTATTGTGAGTTGGTGGGCCGACTCCAATATCCAAACTCGGCTTATGGTCGCTGCAAC
CCTTGTGGTGTCCTTGCTGATGAGTTCCCTGACATTTTGGGCTGTGAATAGCATTCAGCAAGATGCTCGCCTGCAGGACA
ATCGATTTGGCCGGGACTTAGGGTTACTCTTATCATCCAATGTGGCTCCGTTGGTAGCAGACCATAATTATGGAGATTTG
GCCAAACTATCGCGGGAGTTTTATAGCCGCACCTCTAGCATTCGCTACATGATTTATGCCGATGAAGAAGGCAGTATCTA
TTACGGCATCCCCTATTCTGAAACCCAGGTCAATAGTTCCTTGACCTTGCGGCGGTTGATGCAATTGCCAGAGAACTTTA
TGCCGACTGCTGGATCGGTGATGGTGCGGGAGCATTCAACCCCTGACGGTGAAGTGACGGATGTATTTGTCCCTCTATTG
CAGGATGAACAATACTTGGGCGTGTTGGCCATTGGCATCAATCCCAACCCCACGGCAGTAACTTCCTCCCATTTAACCCG
CGATGTCACTATTGCTGTATTTATCACCATTTGGGTGATGGTGATCCTGGGGGCTGTATTTAATGCTCTAATCATTACCA
ACCCGATTAAAGAGTTGGTGGTGGGTGTGAAAACCATTGCCTCCGGCAACTTCAAAAAACGCGTTGACCTCCCGTTTGGC
GGAGAGTTAGGGGAACTGATCTTCAGCTTCAACGATATGGCAGAGCGGCTAGAGCGCTATCAGGAGCAAAATATTGAGGA
ACTGACAGCCCAGAAAGCCAAGCTAGAAACCCTAGTCTCTACCATTGCCGATGGAGCGGTGCTGCTGGATACAGATTTAG
CAGTGATTTTGGCGAACCCCACAGCTCGACGCTTATTTAACTGGGATAGCGAAGTCGTCAGTAAAAATGTTCTCAACCAT
TTACCAGAGCCTGTACAAATTGAGTTGACCCGTCCCCTCTATCAGAGCGCAGCGGGGCAGGAAGGCAGTGAATTTCGAAT
TACCCTGACTGGACCCACCCCCCGCACGGTGCGTATCTTGCTGACAACGGTTCTGGATCAGCAACGGGAGAAGGTCAAAG
GAATCGCCATGACGGTTCAGGACATTACTCGAGAAGTGGAACTCAATGAAGCAAAGAGCCAATTTATTAGCAATATCTCC
CATGAGCTGAGAACGCCTTTATTCAATATCAAATCCTTTATCGAAACCCTCCATGACTATGGCGATGACTTGAGTGCCGA
AGATCGCCAAGAGTTTTTGGATACAGCGAATCGTGAAACGGATCGCTTGACTCGCCTCGTGAATGATGTGCTCGATCTAT
CACGACTGGAGTCGGGCAAGCAATATCGTTTTGAAGCGGTTGATCTGCTCCAGCCCGTAGAGCAAACTCTGAGAACCTAT
CAACTGACGGCTCGCGATCAAGGGATCGAGTTGAGCCACGATATCCAGGCAAATCTCTCGCCCATCTGGGGTAATTATGA
TTTGCTCCTGCAAGTCCTCACCAACTTAATTGGGAATGCCTTGAAATTTACGCTTAAGGGTGGAAAGGTGATGATTCGAG
CTTATCCCTTAGCAGAACATACGAATCAAGTGCGGGTAGAGGTTGCGGATACCGGGATTGGCATTGAGCCGGATGATCAA
GCGGCTATTTTCGATCGGTTTTACCGAGTTGAGAATCGAGTCCATACCTTGGAAGGTACAGGTTTAGGACTCTCGATTGT
CAGGAATATCCTGGACAAGCATCACGCAAGCGTCAATTTAATCAGCGAGTCAGGGGTTGGGACGACCTTCTGGTTTGACC
TCAACGTCTATCGTGACGATTTAGCCAAGCGTGCGGCTGATGAAGCAGACTCTTTAGAAATGCCGGCCCAAGCCTAG

Upstream 100 bases:

>100_bases
CCAATAGCACCAATATAGGAATGAATACCCTCCACATAAACGCTCTGAGGAATGTGCCTTAACTGTTTAAGTCCATTTAG
GTTCTGTTTTGATTCAGCTC

Downstream 100 bases:

>100_bases
CTCACTTACCACCCTAGCCAAGAATGATTAGGGTGCGGGGGTGTTTCAGGTGGGGGAGTAGTGGCCATCTGATCACTGAC
TAGCTTTGACTCTGCACAAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MFERFRKIIVSWWADSNIQTRLMVAATLVVSLLMSSLTFWAVNSIQQDARLQDNRFGRDLGLLLSSNVAPLVADHNYGDL
AKLSREFYSRTSSIRYMIYADEEGSIYYGIPYSETQVNSSLTLRRLMQLPENFMPTAGSVMVREHSTPDGEVTDVFVPLL
QDEQYLGVLAIGINPNPTAVTSSHLTRDVTIAVFITIWVMVILGAVFNALIITNPIKELVVGVKTIASGNFKKRVDLPFG
GELGELIFSFNDMAERLERYQEQNIEELTAQKAKLETLVSTIADGAVLLDTDLAVILANPTARRLFNWDSEVVSKNVLNH
LPEPVQIELTRPLYQSAAGQEGSEFRITLTGPTPRTVRILLTTVLDQQREKVKGIAMTVQDITREVELNEAKSQFISNIS
HELRTPLFNIKSFIETLHDYGDDLSAEDRQEFLDTANRETDRLTRLVNDVLDLSRLESGKQYRFEAVDLLQPVEQTLRTY
QLTARDQGIELSHDIQANLSPIWGNYDLLLQVLTNLIGNALKFTLKGGKVMIRAYPLAEHTNQVRVEVADTGIGIEPDDQ
AAIFDRFYRVENRVHTLEGTGLGLSIVRNILDKHHASVNLISESGVGTTFWFDLNVYRDDLAKRAADEADSLEMPAQA

Sequences:

>Translated_638_residues
MFERFRKIIVSWWADSNIQTRLMVAATLVVSLLMSSLTFWAVNSIQQDARLQDNRFGRDLGLLLSSNVAPLVADHNYGDL
AKLSREFYSRTSSIRYMIYADEEGSIYYGIPYSETQVNSSLTLRRLMQLPENFMPTAGSVMVREHSTPDGEVTDVFVPLL
QDEQYLGVLAIGINPNPTAVTSSHLTRDVTIAVFITIWVMVILGAVFNALIITNPIKELVVGVKTIASGNFKKRVDLPFG
GELGELIFSFNDMAERLERYQEQNIEELTAQKAKLETLVSTIADGAVLLDTDLAVILANPTARRLFNWDSEVVSKNVLNH
LPEPVQIELTRPLYQSAAGQEGSEFRITLTGPTPRTVRILLTTVLDQQREKVKGIAMTVQDITREVELNEAKSQFISNIS
HELRTPLFNIKSFIETLHDYGDDLSAEDRQEFLDTANRETDRLTRLVNDVLDLSRLESGKQYRFEAVDLLQPVEQTLRTY
QLTARDQGIELSHDIQANLSPIWGNYDLLLQVLTNLIGNALKFTLKGGKVMIRAYPLAEHTNQVRVEVADTGIGIEPDDQ
AAIFDRFYRVENRVHTLEGTGLGLSIVRNILDKHHASVNLISESGVGTTFWFDLNVYRDDLAKRAADEADSLEMPAQA
>Mature_638_residues
MFERFRKIIVSWWADSNIQTRLMVAATLVVSLLMSSLTFWAVNSIQQDARLQDNRFGRDLGLLLSSNVAPLVADHNYGDL
AKLSREFYSRTSSIRYMIYADEEGSIYYGIPYSETQVNSSLTLRRLMQLPENFMPTAGSVMVREHSTPDGEVTDVFVPLL
QDEQYLGVLAIGINPNPTAVTSSHLTRDVTIAVFITIWVMVILGAVFNALIITNPIKELVVGVKTIASGNFKKRVDLPFG
GELGELIFSFNDMAERLERYQEQNIEELTAQKAKLETLVSTIADGAVLLDTDLAVILANPTARRLFNWDSEVVSKNVLNH
LPEPVQIELTRPLYQSAAGQEGSEFRITLTGPTPRTVRILLTTVLDQQREKVKGIAMTVQDITREVELNEAKSQFISNIS
HELRTPLFNIKSFIETLHDYGDDLSAEDRQEFLDTANRETDRLTRLVNDVLDLSRLESGKQYRFEAVDLLQPVEQTLRTY
QLTARDQGIELSHDIQANLSPIWGNYDLLLQVLTNLIGNALKFTLKGGKVMIRAYPLAEHTNQVRVEVADTGIGIEPDDQ
AAIFDRFYRVENRVHTLEGTGLGLSIVRNILDKHHASVNLISESGVGTTFWFDLNVYRDDLAKRAADEADSLEMPAQA

Specific function: Member Of The Two-Component Regulatory System Uvry/Bara Involved In The Regulation Of Carbon Metabolism Via The Csra/Csrb Regulatory System. Phosphorylates Uvry, Probably Via A Four-Step Phosphorelay. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=33.75, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786600, Length=384, Percent_Identity=27.8645833333333, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788549, Length=406, Percent_Identity=24.384236453202, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=32.156862745098, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=29.0983606557377, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=27.9693486590038, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.0701754385965, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=31.5175097276265, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=30.5220883534137, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=29.7777777777778, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081816, Length=230, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=210, Percent_Identity=29.5238095238095, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=30.1724137931034, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=27.7056277056277, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=27.9352226720648, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790300, Length=352, Percent_Identity=25, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789403, Length=214, Percent_Identity=32.7102803738318, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=240, Percent_Identity=24.5833333333333, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788279, Length=238, Percent_Identity=25.6302521008403, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71666; Mature: 71666

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFRKIIVSWWADSNIQTRLMVAATLVVSLLMSSLTFWAVNSIQQDARLQDNRFGRDL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GLLLSSNVAPLVADHNYGDLAKLSREFYSRTSSIRYMIYADEEGSIYYGIPYSETQVNSS
HHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCHHCCHH
LTLRRLMQLPENFMPTAGSVMVREHSTPDGEVTDVFVPLLQDEQYLGVLAIGINPNPTAV
HHHHHHHHCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCE
TSSHLTRDVTIAVFITIWVMVILGAVFNALIITNPIKELVVGVKTIASGNFKKRVDLPFG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCC
GELGELIFSFNDMAERLERYQEQNIEELTAQKAKLETLVSTIADGAVLLDTDLAVILANP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECC
TARRLFNWDSEVVSKNVLNHLPEPVQIELTRPLYQSAAGQEGSEFRITLTGPTPRTVRIL
HHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCHHHHHH
LTTVLDQQREKVKGIAMTVQDITREVELNEAKSQFISNISHELRTPLFNIKSFIETLHDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
GDDLSAEDRQEFLDTANRETDRLTRLVNDVLDLSRLESGKQYRFEAVDLLQPVEQTLRTY
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHE
QLTARDQGIELSHDIQANLSPIWGNYDLLLQVLTNLIGNALKFTLKGGKVMIRAYPLAEH
EHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCEEEEEEEECCCC
TNQVRVEVADTGIGIEPDDQAAIFDRFYRVENRVHTLEGTGLGLSIVRNILDKHHASVNL
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCEEE
ISESGVGTTFWFDLNVYRDDLAKRAADEADSLEMPAQA
EECCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFERFRKIIVSWWADSNIQTRLMVAATLVVSLLMSSLTFWAVNSIQQDARLQDNRFGRDL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GLLLSSNVAPLVADHNYGDLAKLSREFYSRTSSIRYMIYADEEGSIYYGIPYSETQVNSS
HHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCHHCCHH
LTLRRLMQLPENFMPTAGSVMVREHSTPDGEVTDVFVPLLQDEQYLGVLAIGINPNPTAV
HHHHHHHHCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCE
TSSHLTRDVTIAVFITIWVMVILGAVFNALIITNPIKELVVGVKTIASGNFKKRVDLPFG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCC
GELGELIFSFNDMAERLERYQEQNIEELTAQKAKLETLVSTIADGAVLLDTDLAVILANP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECC
TARRLFNWDSEVVSKNVLNHLPEPVQIELTRPLYQSAAGQEGSEFRITLTGPTPRTVRIL
HHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCHHHHHH
LTTVLDQQREKVKGIAMTVQDITREVELNEAKSQFISNISHELRTPLFNIKSFIETLHDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
GDDLSAEDRQEFLDTANRETDRLTRLVNDVLDLSRLESGKQYRFEAVDLLQPVEQTLRTY
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHE
QLTARDQGIELSHDIQANLSPIWGNYDLLLQVLTNLIGNALKFTLKGGKVMIRAYPLAEH
EHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCEEEEEEEECCCC
TNQVRVEVADTGIGIEPDDQAAIFDRFYRVENRVHTLEGTGLGLSIVRNILDKHHASVNL
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCEEE
ISESGVGTTFWFDLNVYRDDLAKRAADEADSLEMPAQA
EECCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]