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The map label for this gene is coaD

Identifier: 158337191

GI number: 158337191

Start: 4114211

End: 4114741

Strand: Reverse

Name: coaD

Synonym: AM1_4068

Alternate gene names: 158337191

Gene position: 4114741-4114211 (Counterclockwise)

Preceding gene: 158337193

Following gene: 158337190

Centisome position: 63.27

GC content: 46.89

Gene sequence:

>531_bases
ATGATTGCAGTCTATCCTGGCAGTTTTGACCCCATTACTTTAGGGCATCTCGATATTATTGAACGAGGATGCAACTTGTT
TGGATCAGTCATTGTTGCCGTAGCTCGCAATCCCAACAAAGCGCCTTTGTTTTCGGTTCAACAACGCATTCAGCAAATTC
AAACCTGTACCCAGCACCTTGCCAACTTAGAGCTTGACACATTTGATACACTAACAGTGACTTATACGCAAAAGCGGCAA
GCGCAAGTGTTGTTGCGGGGGTTGAGGGCGTTGTCCGATTTTGAGTATGAGCTACAAATGGCTCATACCAACCACAGCTT
ATCTCCCCATATCGAAACTGTGTTTCTGGCCACCTCCAACGAATATAGCTTTCTCAGCAGTAGCTTAGTCAAAGAGATTG
CCAAGTTTGGTGGATCAGTTGCTCATCTTGTCCCTGAAAACGTTGCCATTGAGTTAGAAGAATGCTTCACCAAGACTCCA
CCTTCAGTGTCGATACCACCGCCAACGGCACCGAGTACGCCCACGGACTAG

Upstream 100 bases:

>100_bases
ATTAGGCGCAAATGAGAAAAAACATTAGCATTTTTTTTGTTTTTAGGATCTCAAAGTTGGAGAGATTAGACTATAATCGC
CTCAACCAAGCACCCAAAAT

Downstream 100 bases:

>100_bases
CGGCTCATCAATCCCAAGGATTGGAATTGCAGCAACAGCTGCAGCGCCTAGAAGAAATTATTGTCCTAGACGGCTTAAAG
ATGCCGTTAACCCGTCGCAC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MIAVYPGSFDPITLGHLDIIERGCNLFGSVIVAVARNPNKAPLFSVQQRIQQIQTCTQHLANLELDTFDTLTVTYTQKRQ
AQVLLRGLRALSDFEYELQMAHTNHSLSPHIETVFLATSNEYSFLSSSLVKEIAKFGGSVAHLVPENVAIELEECFTKTP
PSVSIPPPTAPSTPTD

Sequences:

>Translated_176_residues
MIAVYPGSFDPITLGHLDIIERGCNLFGSVIVAVARNPNKAPLFSVQQRIQQIQTCTQHLANLELDTFDTLTVTYTQKRQ
AQVLLRGLRALSDFEYELQMAHTNHSLSPHIETVFLATSNEYSFLSSSLVKEIAKFGGSVAHLVPENVAIELEECFTKTP
PSVSIPPPTAPSTPTD
>Mature_176_residues
MIAVYPGSFDPITLGHLDIIERGCNLFGSVIVAVARNPNKAPLFSVQQRIQQIQTCTQHLANLELDTFDTLTVTYTQKRQ
AQVLLRGLRALSDFEYELQMAHTNHSLSPHIETVFLATSNEYSFLSSSLVKEIAKFGGSVAHLVPENVAIELEECFTKTP
PSVSIPPPTAPSTPTD

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:
GO:0000166: Phosphopantetheine adenylyltransferase
GO:0003824: Phosphopantetheine adenylyltransferase
GO:0004595: Phosphopantetheine adenylyltransferase
GO:0005524: Phosphopantetheine adenylyltransferase
GO:0005737: Phosphopantetheine adenylyltransferase
GO:0009058: Phosphopantetheine adenylyltransferase
GO:0015937: Phosphopantetheine adenylyltransferase
GO:0016740: Phosphopantetheine adenylyltransferase
GO:0016779: Phosphopantetheine adenylyltransferase

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=146, Percent_Identity=50.6849315068493, Blast_Score=170, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ACAM1 (B0CAI3)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001518366.1
- ProteinModelPortal:   B0CAI3
- SMR:   B0CAI3
- GeneID:   5682872
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4068
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   AMAR329726:AM1_4068-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19352; Mature: 19352

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVYPGSFDPITLGHLDIIERGCNLFGSVIVAVARNPNKAPLFSVQQRIQQIQTCTQHL
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ANLELDTFDTLTVTYTQKRQAQVLLRGLRALSDFEYELQMAHTNHSLSPHIETVFLATSN
HCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCEEEEEEEECC
EYSFLSSSLVKEIAKFGGSVAHLVPENVAIELEECFTKTPPSVSIPPPTAPSTPTD
CHHHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIAVYPGSFDPITLGHLDIIERGCNLFGSVIVAVARNPNKAPLFSVQQRIQQIQTCTQHL
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ANLELDTFDTLTVTYTQKRQAQVLLRGLRALSDFEYELQMAHTNHSLSPHIETVFLATSN
HCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCEEEEEEEECC
EYSFLSSSLVKEIAKFGGSVAHLVPENVAIELEECFTKTPPSVSIPPPTAPSTPTD
CHHHHHHHHHHHHHHHCCCEEEECCCCCEEEHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA