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The map label for this gene is yycF [H]

Identifier: 158337175

GI number: 158337175

Start: 4095139

End: 4095900

Strand: Direct

Name: yycF [H]

Synonym: AM1_4053

Alternate gene names: 158337175

Gene position: 4095139-4095900 (Clockwise)

Preceding gene: 158337172

Following gene: 158337181

Centisome position: 62.97

GC content: 51.97

Gene sequence:

>762_bases
ATGAAAACCCGGATACTTGTTATTGATGATGATCCTGCGATCGCAGAATTGGTTGCGATCAACCTGGAAATGGCAGGCTA
TGATGTAGCCCAAGCAACTGACGGGATTAAAGGGCAAGCGTTGGCCGTCCAGCTACTGCCAGATTTGATCATCTTGGACC
TAATGCTTCCCAAAGTGGATGGCTTTACCATCTGCCAACGATTACGGCGTGATCAGCGGACCGCCGATATTCCAATCCTG
ATGCTTACGGCTCTCAGCCAGACCCAGGATAAGGTCGAAGGATTTAATGCTGGAGCCGATGACTATCTCACCAAGCCCTT
TGAACTAGAGGAAATGCTGGCCCGGGTTCGTGCCCTGCTGCGACGAACCGATCGCATTCCGCAAGCGGCCCGCCATAGTG
AAATTCTCAGCTATGGCCCCCTGACCCTGGTGCCTGAGCGGTTTGAAGTGTTGTGGGTTGATAAAGTGATTAAGCTGACT
CGTTTAGAGTTTGAGCTGCTGCACTGCCTGCTTCAGCGTCATGGCCAAACCGTCTCGCCTAGCGAGATTCTCCAGGAAGT
TTGGGGCTATGATCCGAATGATGATATTGAAACCATTCGGGTGCATGTACGCCATTTGCGCACTAAGCTAGAGCCCGATC
CCCGTCATCCTCAGTACATCAAAACGGTCTATGGGGCGGGATATTGCCTAGAGCTGCCTCACACGGCAGAGGCAGAGAAT
GCTGAAGCCACGAATGAGGAAAACCAAGCTTCTGTTACCTAG

Upstream 100 bases:

>100_bases
TTTACAAGCCTGTTTTAATTCTGAAGAAAACCTTCTGACTCAATCATTGTTAACCGATGCGCTTGCACCTCTTTAATATT
GTCCACACTGAGCAGTTTGC

Downstream 100 bases:

>100_bases
TTCGAAAGTTCACTCGGTTCAGGCACTGAGTCTTCAGGTAACAAGTCTTTAGCAAGATCTTCTTCAATTGCTGCATCAGG
CAGTAAGCTTGTATCGCTAA

Product: two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKTRILVIDDDPAIAELVAINLEMAGYDVAQATDGIKGQALAVQLLPDLIILDLMLPKVDGFTICQRLRRDQRTADIPIL
MLTALSQTQDKVEGFNAGADDYLTKPFELEEMLARVRALLRRTDRIPQAARHSEILSYGPLTLVPERFEVLWVDKVIKLT
RLEFELLHCLLQRHGQTVSPSEILQEVWGYDPNDDIETIRVHVRHLRTKLEPDPRHPQYIKTVYGAGYCLELPHTAEAEN
AEATNEENQASVT

Sequences:

>Translated_253_residues
MKTRILVIDDDPAIAELVAINLEMAGYDVAQATDGIKGQALAVQLLPDLIILDLMLPKVDGFTICQRLRRDQRTADIPIL
MLTALSQTQDKVEGFNAGADDYLTKPFELEEMLARVRALLRRTDRIPQAARHSEILSYGPLTLVPERFEVLWVDKVIKLT
RLEFELLHCLLQRHGQTVSPSEILQEVWGYDPNDDIETIRVHVRHLRTKLEPDPRHPQYIKTVYGAGYCLELPHTAEAEN
AEATNEENQASVT
>Mature_253_residues
MKTRILVIDDDPAIAELVAINLEMAGYDVAQATDGIKGQALAVQLLPDLIILDLMLPKVDGFTICQRLRRDQRTADIPIL
MLTALSQTQDKVEGFNAGADDYLTKPFELEEMLARVRALLRRTDRIPQAARHSEILSYGPLTLVPERFEVLWVDKVIKLT
RLEFELLHCLLQRHGQTVSPSEILQEVWGYDPNDDIETIRVHVRHLRTKLEPDPRHPQYIKTVYGAGYCLELPHTAEAEN
AEATNEENQASVT

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=36.8421052631579, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=242, Percent_Identity=38.0165289256198, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=38.3259911894273, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=37.117903930131, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=34.5991561181435, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=35.2173913043478, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=240, Percent_Identity=35, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=36.4035087719298, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=37.3390557939914, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=32.7433628318584, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.1991341991342, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.8245614035088, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=30.4721030042918, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI145693140, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=134, Percent_Identity=32.8358208955224, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788521, Length=220, Percent_Identity=29.0909090909091, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28656; Mature: 28656

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRILVIDDDPAIAELVAINLEMAGYDVAQATDGIKGQALAVQLLPDLIILDLMLPKVD
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GFTICQRLRRDQRTADIPILMLTALSQTQDKVEGFNAGADDYLTKPFELEEMLARVRALL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTDRIPQAARHSEILSYGPLTLVPERFEVLWVDKVIKLTRLEFELLHCLLQRHGQTVSP
HHHHCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SEILQEVWGYDPNDDIETIRVHVRHLRTKLEPDPRHPQYIKTVYGAGYCLELPHTAEAEN
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCC
AEATNEENQASVT
CCCCCCCCCCCCC
>Mature Secondary Structure
MKTRILVIDDDPAIAELVAINLEMAGYDVAQATDGIKGQALAVQLLPDLIILDLMLPKVD
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GFTICQRLRRDQRTADIPILMLTALSQTQDKVEGFNAGADDYLTKPFELEEMLARVRALL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTDRIPQAARHSEILSYGPLTLVPERFEVLWVDKVIKLTRLEFELLHCLLQRHGQTVSP
HHHHCCCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SEILQEVWGYDPNDDIETIRVHVRHLRTKLEPDPRHPQYIKTVYGAGYCLELPHTAEAEN
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCC
AEATNEENQASVT
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]