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The map label for this gene is yhcW [H]

Identifier: 158336959

GI number: 158336959

Start: 3881074

End: 3881772

Strand: Reverse

Name: yhcW [H]

Synonym: AM1_3832

Alternate gene names: 158336959

Gene position: 3881772-3881074 (Counterclockwise)

Preceding gene: 158336961

Following gene: 158336956

Centisome position: 59.69

GC content: 50.07

Gene sequence:

>699_bases
ATGCCCCTGAAGGCAGTTTTATTTGATTTCAATGGTGTTGTGCTAGATGACGAGCGCATTCACCAGCAGATTATCTGGGA
GATGATGGAGCAAGAAGATTTGCCCCTCACTCAAGAAGAGCTGCAGCTTCACTGTCTGGGTCGAACGGATCGGGCCTGTT
TTCAAGATTTGTATGCCAGCATGGAGCAGCCCCTCAATCAGTTTCATCTGCGGCGGTTGTTGTCCTTCAAAGCGAAGGCT
TACCGCCAATATATAGAATCTTTGGAATACCTACCGGTTTTTGAAGGCCTGATCGAGCTGATTGGGCAATGCCTAGATGC
GGGGTTGACCCTGGCCATCGTCAGTGGTGCGCTCCGGTCAGAAGTGCGACTGGTGCTTAAACAACTGTCTTTGGAGGAGG
CCTTTCCCATTACCGTCACCTCGGAAGATGTCAAAAGAAGTAAGCCGGATCCAGCCGGGTATCAATTGGCGATTAAGCGC
CTCAATCGTAAGTTTCCTGGGTTGGATTTAGACCCTTGTGATTGCTTGGCGATTGAGGATAGCTTTGCGGGTATTCAGGC
AGCCAAACAGGCCCAAGTCCCTGTGGTGGGGGTGGCGCATACCTTGCCTTTTCATATGCTGCAACGTCAGGCGAATTGGT
GTGTTGATTATCTGCACCAGATTGAACTCGATCGAATTCAAGCCATTTTTGCGCGTTAA

Upstream 100 bases:

>100_bases
CGATCGCATTGCCTGAATCGGTCTGTCAGCCTACCGCGAAATTGAAACGAGTGTAGCAGTAATTGCTGCGGTTTGGTTAT
TGTAAGTTTGATAAGCTCCC

Downstream 100 bases:

>100_bases
AATCACGGGTCACTGACGAAGCCCTCCCTTACTCCTGGGCAGGAGGGGGCGGTTTTCCTAGAGTCGTTATGTAGAGGACC
GCTTCTTCTTCTGGGATGCC

Product: HAD family hydrolase

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MPLKAVLFDFNGVVLDDERIHQQIIWEMMEQEDLPLTQEELQLHCLGRTDRACFQDLYASMEQPLNQFHLRRLLSFKAKA
YRQYIESLEYLPVFEGLIELIGQCLDAGLTLAIVSGALRSEVRLVLKQLSLEEAFPITVTSEDVKRSKPDPAGYQLAIKR
LNRKFPGLDLDPCDCLAIEDSFAGIQAAKQAQVPVVGVAHTLPFHMLQRQANWCVDYLHQIELDRIQAIFAR

Sequences:

>Translated_232_residues
MPLKAVLFDFNGVVLDDERIHQQIIWEMMEQEDLPLTQEELQLHCLGRTDRACFQDLYASMEQPLNQFHLRRLLSFKAKA
YRQYIESLEYLPVFEGLIELIGQCLDAGLTLAIVSGALRSEVRLVLKQLSLEEAFPITVTSEDVKRSKPDPAGYQLAIKR
LNRKFPGLDLDPCDCLAIEDSFAGIQAAKQAQVPVVGVAHTLPFHMLQRQANWCVDYLHQIELDRIQAIFAR
>Mature_231_residues
PLKAVLFDFNGVVLDDERIHQQIIWEMMEQEDLPLTQEELQLHCLGRTDRACFQDLYASMEQPLNQFHLRRLLSFKAKAY
RQYIESLEYLPVFEGLIELIGQCLDAGLTLAIVSGALRSEVRLVLKQLSLEEAFPITVTSEDVKRSKPDPAGYQLAIKRL
NRKFPGLDLDPCDCLAIEDSFAGIQAAKQAQVPVVGVAHTLPFHMLQRQANWCVDYLHQIELDRIQAIFAR

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 26509; Mature: 26378

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKAVLFDFNGVVLDDERIHQQIIWEMMEQEDLPLTQEELQLHCLGRTDRACFQDLYAS
CCCHHEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
MEQPLNQFHLRRLLSFKAKAYRQYIESLEYLPVFEGLIELIGQCLDAGLTLAIVSGALRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVRLVLKQLSLEEAFPITVTSEDVKRSKPDPAGYQLAIKRLNRKFPGLDLDPCDCLAIED
HHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
SFAGIQAAKQAQVPVVGVAHTLPFHMLQRQANWCVDYLHQIELDRIQAIFAR
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLKAVLFDFNGVVLDDERIHQQIIWEMMEQEDLPLTQEELQLHCLGRTDRACFQDLYAS
CCHHEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
MEQPLNQFHLRRLLSFKAKAYRQYIESLEYLPVFEGLIELIGQCLDAGLTLAIVSGALRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVRLVLKQLSLEEAFPITVTSEDVKRSKPDPAGYQLAIKRLNRKFPGLDLDPCDCLAIED
HHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
SFAGIQAAKQAQVPVVGVAHTLPFHMLQRQANWCVDYLHQIELDRIQAIFAR
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]