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The map label for this gene is ubiA [H]

Identifier: 158336734

GI number: 158336734

Start: 3657191

End: 3658078

Strand: Reverse

Name: ubiA [H]

Synonym: AM1_3602

Alternate gene names: 158336734

Gene position: 3658078-3657191 (Counterclockwise)

Preceding gene: 158336735

Following gene: 158336731

Centisome position: 56.25

GC content: 51.01

Gene sequence:

>888_bases
ATGGCCCGCCTTCAGTCCAAACCGTCTACTCCCACCTGGTTCGCAATCATCAAACTGTTGCGATGGGATAAACCAGAAGG
CCGCTTAATCCTGATGATTCCGGCATTATGGGCCATTGTCCTGGCAGCCCAAGGTAAACCCTCTTTAGGGCTCGTTACTA
TCATCATTACCGGCAGTCTGGCCACCAGTGCTGCCGGTTGTGTTGTGAATGATTTGTGGGATCGCAATATTGATCCCCAG
GTTCAACGCACGCGCAAGCGACCTTTAGCCGATCGGTCTCTGACCATTCGGGTGGGTTTAGCGATTGCTTTTCTTGCTTT
TGCCTGTGCGTTTGGACTATCCCGATTCCTCAACCCTCTGAGTTTTGGGTTGTGCGTCGCTGCAGTTCCCGTGATTATCT
GCTACCCATTAGCCAAGCGAGTGTTTCCAGTTCCACAATTAGTTTTGGCTATTGCTTGGGGCTTTTCAGTGCTGATTAGC
TGGAGTGCAGCGGTTGGCAATCTTAGCCTGGGAGCCTGGCTGTTGTGGGCTGCGACAGTACTGTGGACGTTGGGCTTTGA
CACTATCTATGCCATGCCTGACCGCCCCGATGATCGGCGGCTGGGCATTAATTCCAGTGCGTTATTCTTTGGCAACTATG
CCGAAGCTGCTATTGCCTGCTTTTTAGTAGCTACTGTTATCTGTTTAGGAATGCTGGGGTACGCCCTCAATCTCCACTTT
GGGTATTGGACATCCCTAGGACTCAGTACCTATCTCTGGTGGCGGCAAATTTACCGACTCAGGCGTAAAAACCTAGTTCC
TAGCGCCTATGGTCAGCTTTTTCGCCAAAACGTCTGGATCGGATTACTCTTATTAGTCGGCATGATTACCGGATCATTGC
TGCGCTAG

Upstream 100 bases:

>100_bases
CATCAAATATCTAGCGAATCCTGCCTCATCATTTCCATTTCTTGATCCCATGCTTTTCAATCTTTGGCATGATTAGTAAT
GGAATTCACGATGAAACAGC

Downstream 100 bases:

>100_bases
CTACCGCGCATCTGTATCTGAGATGTTAATCGCCACGGGAATATCGACGGGAGATTGGTCAATGGCAATCAAAAGATCCG
AGGGCTTCAAGTTATCCGAT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MARLQSKPSTPTWFAIIKLLRWDKPEGRLILMIPALWAIVLAAQGKPSLGLVTIIITGSLATSAAGCVVNDLWDRNIDPQ
VQRTRKRPLADRSLTIRVGLAIAFLAFACAFGLSRFLNPLSFGLCVAAVPVIICYPLAKRVFPVPQLVLAIAWGFSVLIS
WSAAVGNLSLGAWLLWAATVLWTLGFDTIYAMPDRPDDRRLGINSSALFFGNYAEAAIACFLVATVICLGMLGYALNLHF
GYWTSLGLSTYLWWRQIYRLRRKNLVPSAYGQLFRQNVWIGLLLLVGMITGSLLR

Sequences:

>Translated_295_residues
MARLQSKPSTPTWFAIIKLLRWDKPEGRLILMIPALWAIVLAAQGKPSLGLVTIIITGSLATSAAGCVVNDLWDRNIDPQ
VQRTRKRPLADRSLTIRVGLAIAFLAFACAFGLSRFLNPLSFGLCVAAVPVIICYPLAKRVFPVPQLVLAIAWGFSVLIS
WSAAVGNLSLGAWLLWAATVLWTLGFDTIYAMPDRPDDRRLGINSSALFFGNYAEAAIACFLVATVICLGMLGYALNLHF
GYWTSLGLSTYLWWRQIYRLRRKNLVPSAYGQLFRQNVWIGLLLLVGMITGSLLR
>Mature_294_residues
ARLQSKPSTPTWFAIIKLLRWDKPEGRLILMIPALWAIVLAAQGKPSLGLVTIIITGSLATSAAGCVVNDLWDRNIDPQV
QRTRKRPLADRSLTIRVGLAIAFLAFACAFGLSRFLNPLSFGLCVAAVPVIICYPLAKRVFPVPQLVLAIAWGFSVLISW
SAAVGNLSLGAWLLWAATVLWTLGFDTIYAMPDRPDDRRLGINSSALFFGNYAEAAIACFLVATVICLGMLGYALNLHFG
YWTSLGLSTYLWWRQIYRLRRKNLVPSAYGQLFRQNVWIGLLLLVGMITGSLLR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=280, Percent_Identity=32.5, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=34.1818181818182, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17553718, Length=290, Percent_Identity=33.1034482758621, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32565247, Length=291, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17553720, Length=348, Percent_Identity=28.1609195402299, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565245, Length=144, Percent_Identity=34.7222222222222, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=34.965034965035, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=291, Percent_Identity=27.8350515463918, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=37.8091872791519, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32599; Mature: 32468

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLQSKPSTPTWFAIIKLLRWDKPEGRLILMIPALWAIVLAAQGKPSLGLVTIIITGSL
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCH
ATSAAGCVVNDLWDRNIDPQVQRTRKRPLADRSLTIRVGLAIAFLAFACAFGLSRFLNPL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
SFGLCVAAVPVIICYPLAKRVFPVPQLVLAIAWGFSVLISWSAAVGNLSLGAWLLWAATV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LWTLGFDTIYAMPDRPDDRRLGINSSALFFGNYAEAAIACFLVATVICLGMLGYALNLHF
HHHHCHHHEEECCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYWTSLGLSTYLWWRQIYRLRRKNLVPSAYGQLFRQNVWIGLLLLVGMITGSLLR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARLQSKPSTPTWFAIIKLLRWDKPEGRLILMIPALWAIVLAAQGKPSLGLVTIIITGSL
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEEEEECCH
ATSAAGCVVNDLWDRNIDPQVQRTRKRPLADRSLTIRVGLAIAFLAFACAFGLSRFLNPL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
SFGLCVAAVPVIICYPLAKRVFPVPQLVLAIAWGFSVLISWSAAVGNLSLGAWLLWAATV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LWTLGFDTIYAMPDRPDDRRLGINSSALFFGNYAEAAIACFLVATVICLGMLGYALNLHF
HHHHCHHHEEECCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYWTSLGLSTYLWWRQIYRLRRKNLVPSAYGQLFRQNVWIGLLLLVGMITGSLLR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA