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The map label for this gene is rpoC1

Identifier: 158336725

GI number: 158336725

Start: 3644614

End: 3646485

Strand: Direct

Name: rpoC1

Synonym: AM1_3593

Alternate gene names: 158336725

Gene position: 3644614-3646485 (Clockwise)

Preceding gene: 158336724

Following gene: 158336726

Centisome position: 56.04

GC content: 49.89

Gene sequence:

>1872_bases
ATGCCAAAGCTCGAACAACGATTTGACTACGTCAAAATTGGGCTAGCCTCTCCGGAACGGATCCGGCAGTGGGGGGAGCG
TACCTTACCCAATAACCAAGTGGTCGGTGAAGTCACCAAACCAGAAACCATCAACTACCGAACCTTAAAACCGGAGATGG
ATGGTCTATTTTGTGAGCGGATCTTTGGTCCTGCCAAGGATTGGGAATGTCACTGTGGCAAATATAAGCGGGTTCGGCAC
CGAGGTATCGTCTGTGAGCGCTGTGGCGTCGAGGTGACTGAATCGCGGGTGCGACGACATCGCATGGGCTACATTAAATT
AGCCGCTCCCGTGACCCACGTTTGGTACTTGAAAGGTATTCCTAGCTATATGGCTACGTTGCTGGACATGCCTCTGCGGG
ATGTAGAGCAGATTGTTTATTTCAATGCCTATGTGGTTTTGGATCCAGGCAACGCAGATACCTTGTCCTATAAGCAACTC
CTAACGGAAGATCAGTGGATAGAAATTGAGGATCAAATCTATAGCGAGGATTCTCAGCTAGAAGGGATTGAAGTCGGCAT
TGGTGCTGAGGCTGTGCAAAGACTGCTCCAGGACATCAAGCTTGAAACAGAAGCTGAAACTCTGAGAGAGGACATTGGCA
ACGCTAAGGGCCAGAAAAGAGCCAAGCTGATTAAGCGATTGCGGGTCATCGATAACTTTGTAGGAACAGGCTCTCAAACC
GATTGGATGGTTCTGAGCGTGATCCCAGTGATTCCACCAGATTTGAGACCAATGGTGCAGTTGGATGGTGGACGATTTGC
CACCTCTGACCTCAATGATCTGTACCGTCGAGTGATTAACCGCAATAATCGCCTCGCTCGATTGCAAGAGATTTTAGCTC
CAGAGATTATCGTTCGAAATGAGAAACGGATGTTGCAAGAGGCGGTGGATGCCTTGATCGACAACGGCCGCCGAGGTCGA
ACCGTGGTGGGAGCGAATAACCGTCCCTTAAAATCCTTGTCTGATATCATTGAAGGAAAGCAAGGTCGTTTCCGTCAGAA
CCTTCTGGGTAAACGGGTTGACTACTCCGGTCGTTCTGTGATCGTCGTGGGTCCCAAGCTAAAAATGCACCAGTGCGGCT
TACCCAAAGAGATGGCAATTGAACTCTTTCAGCCCTTTGTCATTCACCGTTTGATTGGCCAAGGTTTAGTGAATAACATC
AAAGCGGCTAAGCGTCTGATTCAGCGTAATGATCCCGTTATCTGGGATGTGTTGGAAGAAGTGATTGAAGGGCATCCAGT
GATGCTCAACCGGGCGCCGACCTTGCACCGATTGGGAATTCAAGCGTTTGAACCCATCTTGGTGGATGGTCGAGCGATTC
AGCTACATCCCTTGGTTTGCCCGGCCTTTAACGCCGACTTTGACGGAGACCAAATGGCGGTGCATGTGCCCCTGTCCATT
GAAGCTCAGTCTGAAGCCCGTCTTCTGATGTTGGCCTCGAATAATATTCTGTCGCCAGCAACAGGGCGTCCCATTGTTAC
GCCCAGTCAGGACATGGTGTTGGGAGCTTACTATCTGACTGCAGATAATCCAGGCCGGCAAAATGGGGCAGGCAAGTATT
TTGCGGGTTTAGACGATGCCATTATGGCTTATGAGCAGCAGCAAGTTGACTTACATGCCTATGTTTGGGTGCGGTTTGAC
GGCCCAGTAGATGATGGCGAAGACGACGTTGAGCCTGAGGTAGAAACCTCTGCGGATGGCGTTGTCACTCAAACTTACCC
TTCTCGTCGAATTCGCAAGGATGCAGACGGGACATTGATTTCGCAATATATTCGCACGACCCCTGGTCGCATTATTTACA
ACAAAACCATCCAGGATTCATTGGCTAGCTAA

Upstream 100 bases:

>100_bases
AAGTTAATTGTCTGCCGGACAGTAGGGTTGAACGGATGATCCCTTCAACCCAATTTATTTCGAAGCATATTTAGCAAGGA
ACAAGAGGAAGCTAATCGCG

Downstream 100 bases:

>100_bases
GTTGGAGAAGCAGATTATGGCAGAAAATTCCACCCATTCCCCTCGCGAGGCGACTCCACCAGCCTTTTGCAACAAAATTG
TGAATAAAGGTCAGCTGAAG

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MPKLEQRFDYVKIGLASPERIRQWGERTLPNNQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRH
RGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSYMATLLDMPLRDVEQIVYFNAYVVLDPGNADTLSYKQL
LTEDQWIEIEDQIYSEDSQLEGIEVGIGAEAVQRLLQDIKLETEAETLREDIGNAKGQKRAKLIKRLRVIDNFVGTGSQT
DWMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGR
TVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIGQGLVNNI
KAAKRLIQRNDPVIWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSI
EAQSEARLLMLASNNILSPATGRPIVTPSQDMVLGAYYLTADNPGRQNGAGKYFAGLDDAIMAYEQQQVDLHAYVWVRFD
GPVDDGEDDVEPEVETSADGVVTQTYPSRRIRKDADGTLISQYIRTTPGRIIYNKTIQDSLAS

Sequences:

>Translated_623_residues
MPKLEQRFDYVKIGLASPERIRQWGERTLPNNQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRH
RGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSYMATLLDMPLRDVEQIVYFNAYVVLDPGNADTLSYKQL
LTEDQWIEIEDQIYSEDSQLEGIEVGIGAEAVQRLLQDIKLETEAETLREDIGNAKGQKRAKLIKRLRVIDNFVGTGSQT
DWMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGR
TVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIGQGLVNNI
KAAKRLIQRNDPVIWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSI
EAQSEARLLMLASNNILSPATGRPIVTPSQDMVLGAYYLTADNPGRQNGAGKYFAGLDDAIMAYEQQQVDLHAYVWVRFD
GPVDDGEDDVEPEVETSADGVVTQTYPSRRIRKDADGTLISQYIRTTPGRIIYNKTIQDSLAS
>Mature_622_residues
PKLEQRFDYVKIGLASPERIRQWGERTLPNNQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRHR
GIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSYMATLLDMPLRDVEQIVYFNAYVVLDPGNADTLSYKQLL
TEDQWIEIEDQIYSEDSQLEGIEVGIGAEAVQRLLQDIKLETEAETLREDIGNAKGQKRAKLIKRLRVIDNFVGTGSQTD
WMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRT
VVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIGQGLVNNIK
AAKRLIQRNDPVIWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSIE
AQSEARLLMLASNNILSPATGRPIVTPSQDMVLGAYYLTADNPGRQNGAGKYFAGLDDAIMAYEQQQVDLHAYVWVRFDG
PVDDGEDDVEPEVETSADGVVTQTYPSRRIRKDADGTLISQYIRTTPGRIIYNKTIQDSLAS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:
GO:0003677: DNA-directed RNA polymerase subunit gamma
GO:0003899: DNA-directed RNA polymerase subunit gamma
GO:0006351: DNA-directed RNA polymerase subunit gamma
GO:0016740: DNA-directed RNA polymerase subunit gamma
GO:0016779: DNA-directed RNA polymerase subunit gamma

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily

Homologues:

Organism=Homo sapiens, GI4505939, Length=495, Percent_Identity=27.0707070707071, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI39725938, Length=217, Percent_Identity=34.1013824884793, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=31.6964285714286, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI2367335, Length=555, Percent_Identity=60.9009009009009, Blast_Score=726, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=566, Percent_Identity=24.9116607773852, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25145495, Length=569, Percent_Identity=25.6590509666081, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324690, Length=227, Percent_Identity=36.5638766519824, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320061, Length=561, Percent_Identity=26.3814616755793, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324917, Length=291, Percent_Identity=26.1168384879725, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17530899, Length=486, Percent_Identity=25.5144032921811, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360912, Length=231, Percent_Identity=32.4675324675325, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17647875, Length=343, Percent_Identity=27.9883381924198, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC1_ACAM1 (B0C2D1)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517899.1
- ProteinModelPortal:   B0C2D1
- SMR:   B0C2D1
- GeneID:   5682399
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_3593
- HOGENOM:   HBG285548
- OMA:   HVWYLKG
- ProtClustDB:   PRK02625
- BioCyc:   AMAR329726:AM1_3593-MONOMER
- HAMAP:   MF_01323
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755
- SMART:   SM00663
- TIGRFAMs:   TIGR02387

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3

EC number: =2.7.7.6

Molecular weight: Translated: 70372; Mature: 70241

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLEQRFDYVKIGLASPERIRQWGERTLPNNQVVGEVTKPETINYRTLKPEMDGLFCER
CCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHHH
IFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGI
HCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHCH
PSYMATLLDMPLRDVEQIVYFNAYVVLDPGNADTLSYKQLLTEDQWIEIEDQIYSEDSQL
HHHHHHHHCCCHHHHHHHHEEEEEEEECCCCCCHHHHHHHHCCCCCEEEHHHHCCCCCCC
EGIEVGIGAEAVQRLLQDIKLETEAETLREDIGNAKGQKRAKLIKRLRVIDNFVGTGSQT
CCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DWMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRN
CEEEEEEECCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEECC
EKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSV
HHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEE
IVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIGQGLVNNIKAAKRLIQRNDPVIWDVLEE
EEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSI
HHCCCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEE
EAQSEARLLMLASNNILSPATGRPIVTPSQDMVLGAYYLTADNPGRQNGAGKYFAGLDDA
ECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHH
IMAYEQQQVDLHAYVWVRFDGPVDDGEDDVEPEVETSADGVVTQTYPSRRIRKDADGTLI
HHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCCCHHHH
SQYIRTTPGRIIYNKTIQDSLAS
HHHHHCCCCCEEECCCHHHHHCC
>Mature Secondary Structure 
PKLEQRFDYVKIGLASPERIRQWGERTLPNNQVVGEVTKPETINYRTLKPEMDGLFCER
CCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHHH
IFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGI
HCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHCH
PSYMATLLDMPLRDVEQIVYFNAYVVLDPGNADTLSYKQLLTEDQWIEIEDQIYSEDSQL
HHHHHHHHCCCHHHHHHHHEEEEEEEECCCCCCHHHHHHHHCCCCCEEEHHHHCCCCCCC
EGIEVGIGAEAVQRLLQDIKLETEAETLREDIGNAKGQKRAKLIKRLRVIDNFVGTGSQT
CCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DWMVLSVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRN
CEEEEEEECCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEECC
EKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSV
HHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEE
IVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIGQGLVNNIKAAKRLIQRNDPVIWDVLEE
EEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VIEGHPVMLNRAPTLHRLGIQAFEPILVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLSI
HHCCCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEE
EAQSEARLLMLASNNILSPATGRPIVTPSQDMVLGAYYLTADNPGRQNGAGKYFAGLDDA
ECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHH
IMAYEQQQVDLHAYVWVRFDGPVDDGEDDVEPEVETSADGVVTQTYPSRRIRKDADGTLI
HHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHCCCCCHHHH
SQYIRTTPGRIIYNKTIQDSLAS
HHHHHCCCCCEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA