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The map label for this gene is dapL [H]

Identifier: 158336709

GI number: 158336709

Start: 3625442

End: 3626653

Strand: Direct

Name: dapL [H]

Synonym: AM1_3577

Alternate gene names: 158336709

Gene position: 3625442-3626653 (Clockwise)

Preceding gene: 158336708

Following gene: 158336710

Centisome position: 55.74

GC content: 51.57

Gene sequence:

>1212_bases
ATGAGTTTGGATTGGATCAAACCGGCTGACCGGTTGAGTGCATTGCCACCCTATGTATTTGCCCGTTTAGATGAACTCAA
AACCTCGGCTCGTCAGCAAGGGCTGGATCTGATTGATTTGGGTATGGGAAACCCGGATGGTCCGCCGCCCGAACCGGTGA
TAGAAGCTGCGATCGCAGCCCTCAAATCCCCCAATACTCATGGCTATCCTCCCTTTGAAGGCCATGCAGACTTCCGTCAT
ACCATTACCGATTGGTATCACCGCCGATATGACGTATTGCTCGATCCGGAGATTGAGGCTCTACCGTTACTTGGCTCTAA
AGAAGGCTTAACCCACCTCGCTTTAGCCTATATCAATCCGGGGGATGTGGTGTTAGTCCCCAATCCAGCCTATCCACCCC
ACTTTCGAGGCCCAGCCCTAGCCGGAGCCGAAATTTACGGTTTGCCCTTAAAGGCAGAAAATGACTGGCTGATTGACTTA
GGCAGCATTCCTGATCAGGTGGCAGAACGGGCCAAAATCCTCTACTTCAATTACCCCAGTAATCCAACGACGGCTGTGGC
CCCCCGAGAGCTGTTTACAGAAATTGTCGCCTTTGCGCGTAAACATCAAATTTTGCTGGTTCATGACCTCTGCTATGCCG
AGCTAGCGTTTGATGGCTATCAGCCGGTCAGTCTGCTGGAAATTCCAGGGGCAAAGGAGATTGGCGTTGAGTTTCATACC
CTGTCCAAAACCTACAATATGGCCGGTTGGCGGGTGGGGTTTGTGGTAGGCAATCCCCAAATTATTCAAGGGCTGCGAAC
TTTGAAAACTAACTTAGACTATGGCATTTTTGCTGTGGTTCAGGCGGCCGCCCAAACTGCACTGCAACTCCCCGATAGCC
ATTTGCAAGGGGTGCAGCAGCGCTACCGAGAGCGACGAGATTTTGTCATTGCCGGATTGGGTGAGCTGGGCTGGCACATC
CCCAAAACGAAAGCAACCATGTATTTATGGGCACCCTGTCCTGTAGAGATGTCCTCCGCAGACTTTGCCTTAAAGCTGAT
CCAAGAAACCGGAATTGTGATGACGCCGGGGAGTGCCTTTGGTCATCATGGCGAAGGCTATTTGCGGATTAGCTTGATCG
CAGACTGCGATCGCCTCGGTGAAGCCATTCATCGTATTCGTCAATCTCAGATTTGTGGTACTCCTACCAGCAACGTTATC
AGCCCATCATGA

Upstream 100 bases:

>100_bases
CGGTGATGCCAGATCAGCTGCTAGCGGCGATGGTCTCTACGGCTAGTCTCATGGCGGACGGTAGTGCTAATCCAAGCTCT
CCATCGGAAGAGGTTTGCCC

Downstream 100 bases:

>100_bases
AGGGAAGGTTTCTAATATCTGTGATCATTTGTTGTTTCTCAAGTCAGAGCGGCTTCCCCCTGCTATGTGGGAGGAGCCAT
GACCGTTTCTAGAAGCATCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSLDWIKPADRLSALPPYVFARLDELKTSARQQGLDLIDLGMGNPDGPPPEPVIEAAIAALKSPNTHGYPPFEGHADFRH
TITDWYHRRYDVLLDPEIEALPLLGSKEGLTHLALAYINPGDVVLVPNPAYPPHFRGPALAGAEIYGLPLKAENDWLIDL
GSIPDQVAERAKILYFNYPSNPTTAVAPRELFTEIVAFARKHQILLVHDLCYAELAFDGYQPVSLLEIPGAKEIGVEFHT
LSKTYNMAGWRVGFVVGNPQIIQGLRTLKTNLDYGIFAVVQAAAQTALQLPDSHLQGVQQRYRERRDFVIAGLGELGWHI
PKTKATMYLWAPCPVEMSSADFALKLIQETGIVMTPGSAFGHHGEGYLRISLIADCDRLGEAIHRIRQSQICGTPTSNVI
SPS

Sequences:

>Translated_403_residues
MSLDWIKPADRLSALPPYVFARLDELKTSARQQGLDLIDLGMGNPDGPPPEPVIEAAIAALKSPNTHGYPPFEGHADFRH
TITDWYHRRYDVLLDPEIEALPLLGSKEGLTHLALAYINPGDVVLVPNPAYPPHFRGPALAGAEIYGLPLKAENDWLIDL
GSIPDQVAERAKILYFNYPSNPTTAVAPRELFTEIVAFARKHQILLVHDLCYAELAFDGYQPVSLLEIPGAKEIGVEFHT
LSKTYNMAGWRVGFVVGNPQIIQGLRTLKTNLDYGIFAVVQAAAQTALQLPDSHLQGVQQRYRERRDFVIAGLGELGWHI
PKTKATMYLWAPCPVEMSSADFALKLIQETGIVMTPGSAFGHHGEGYLRISLIADCDRLGEAIHRIRQSQICGTPTSNVI
SPS
>Mature_402_residues
SLDWIKPADRLSALPPYVFARLDELKTSARQQGLDLIDLGMGNPDGPPPEPVIEAAIAALKSPNTHGYPPFEGHADFRHT
ITDWYHRRYDVLLDPEIEALPLLGSKEGLTHLALAYINPGDVVLVPNPAYPPHFRGPALAGAEIYGLPLKAENDWLIDLG
SIPDQVAERAKILYFNYPSNPTTAVAPRELFTEIVAFARKHQILLVHDLCYAELAFDGYQPVSLLEIPGAKEIGVEFHTL
SKTYNMAGWRVGFVVGNPQIIQGLRTLKTNLDYGIFAVVQAAAQTALQLPDSHLQGVQQRYRERRDFVIAGLGELGWHIP
KTKATMYLWAPCPVEMSSADFALKLIQETGIVMTPGSAFGHHGEGYLRISLIADCDRLGEAIHRIRQSQICGTPTSNVIS
PS

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=23.8693467336683, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=23.8693467336683, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI56713254, Length=337, Percent_Identity=25.2225519287834, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI56713256, Length=337, Percent_Identity=25.2225519287834, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169881281, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507369, Length=412, Percent_Identity=23.5436893203883, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=42.6315789473684, Blast_Score=343, Evalue=8e-96,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=23.9795918367347, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=24.4031830238727, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=399, Percent_Identity=24.3107769423559, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=399, Percent_Identity=24.3107769423559, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=325, Percent_Identity=23.3846153846154, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=25.668449197861, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.6503856041131, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28573069, Length=379, Percent_Identity=24.802110817942, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=379, Percent_Identity=24.802110817942, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=379, Percent_Identity=24.802110817942, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=379, Percent_Identity=24.802110817942, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=23.2804232804233, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44408; Mature: 44277

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDWIKPADRLSALPPYVFARLDELKTSARQQGLDLIDLGMGNPDGPPPEPVIEAAIAA
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHH
LKSPNTHGYPPFEGHADFRHTITDWYHRRYDVLLDPEIEALPLLGSKEGLTHLALAYINP
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCEEEEEEECC
GDVVLVPNPAYPPHFRGPALAGAEIYGLPLKAENDWLIDLGSIPDQVAERAKILYFNYPS
CCEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHCCEEEEEEECCC
NPTTAVAPRELFTEIVAFARKHQILLVHDLCYAELAFDGYQPVSLLEIPGAKEIGVEFHT
CCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCEEEEECCCCHHHCCEEEE
LSKTYNMAGWRVGFVVGNPQIIQGLRTLKTNLDYGIFAVVQAAAQTALQLPDSHLQGVQQ
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYRERRDFVIAGLGELGWHIPKTKATMYLWAPCPVEMSSADFALKLIQETGIVMTPGSAF
HHHHHCCEEEEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEECCCCCC
GHHGEGYLRISLIADCDRLGEAIHRIRQSQICGTPTSNVISPS
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SLDWIKPADRLSALPPYVFARLDELKTSARQQGLDLIDLGMGNPDGPPPEPVIEAAIAA
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHH
LKSPNTHGYPPFEGHADFRHTITDWYHRRYDVLLDPEIEALPLLGSKEGLTHLALAYINP
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCEEEEEEECC
GDVVLVPNPAYPPHFRGPALAGAEIYGLPLKAENDWLIDLGSIPDQVAERAKILYFNYPS
CCEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHCCEEEEEEECCC
NPTTAVAPRELFTEIVAFARKHQILLVHDLCYAELAFDGYQPVSLLEIPGAKEIGVEFHT
CCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCEEEEECCCCHHHCCEEEE
LSKTYNMAGWRVGFVVGNPQIIQGLRTLKTNLDYGIFAVVQAAAQTALQLPDSHLQGVQQ
HHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYRERRDFVIAGLGELGWHIPKTKATMYLWAPCPVEMSSADFALKLIQETGIVMTPGSAF
HHHHHCCEEEEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEECCCCCC
GHHGEGYLRISLIADCDRLGEAIHRIRQSQICGTPTSNVISPS
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA