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The map label for this gene is clpX

Identifier: 158336586

GI number: 158336586

Start: 3479867

End: 3481210

Strand: Direct

Name: clpX

Synonym: AM1_3450

Alternate gene names: 158336586

Gene position: 3479867-3481210 (Clockwise)

Preceding gene: 158336585

Following gene: 158336587

Centisome position: 53.51

GC content: 47.92

Gene sequence:

>1344_bases
ATGTCTAAATATGACTCCCATCTCAAATGTTCATTTTGTGGTAAATCTCAAGAACAGGTCCGCAAATTAATTGCTGGGCC
GGGGGTCTATATCTGCGATGAATGCGTAGATTTGTGCAATGAAATTCTGGACGAAGAGCTATTCGATACGGCTAGTAGTA
TGCCTGCTGCCAGTAGAGCCCCGGTGGCAGAGCGTAAACGGTCTCAATCTGCTCCCTTGTCTCTCAATCAGATTCCTAAA
CCACGGGATATCAAGTCATATTTAGATGAACATGTCATCGGACAAGACGAAGCGAAAAAAGTCTTGTCCGTTGCCGTATA
TAACCATTACAAGCGTTTGAGTATTAGCCAAGCTTCGGCAGATTCTGTTGCTGAGTTGGATGATGCCATCGAATTACAAA
AATCCAACATTTTGCTGATCGGTCCTACAGGATGTGGCAAAACGTTGCTGGCTCAGACATTGGCTCAAATGCTCGATGTT
CCGTTTGCGGTGGCAGATGCCACAACCTTGACAGAGGCTGGCTATGTAGGGGAAGACGTCGAAAATATTCTATTGCGACT
CCTCCAGGTTGCCGATTTGGATGTAGAGGAAGCCCAAAGAGGGATCATCTACATCGATGAAATTGATAAGGTGGCTCGTA
AGAGTGAGAATCCTTCGATTACGCGAGATGTGTCTGGCGAAGGGGTGCAGCAGGCTCTGTTAAAAATGCTGGAAGGGACA
GTGGCTAATGTTCCTCCCCAAGGTGGGCGCAAGCACCCTTACCAAGACTGTATTCAAATCGATACCACTAACATTCTATT
TATCTGTGGTGGGGCGTTTGTCGGTCTCGATAAAATTATTGAGCAGCGGACGGGCAAAAAAGCCATGGGATTCATCCAAG
ATGGTGAACTCCGAGCAAAAGAGCAGCGCACTGCCGATATGCTGAGAGATTTGGAAGCTGAAGATTTAGTCAAATTTGGG
ATGATTCCTGAATTTACTGGTCGGATTCCGGTGATGTCTGTGATTGATGCTCTGGATGAAGATGTACTCTGTCAGATTCT
GACGGAGCCACGCAATGCTTTGGTGAAGCAATATCAAAAGCTATTGCGGATGGATCGGGTAGAGCTGGAGTTTCAGCCTG
ATGCGATTCGCGCCATTGCTCAGGAAGCCTATCGACGCAGGACGGGAGCCAGGGCTCTGCGGGCTATTGTCGAAGAGATT
ATGCTGGATGTGATGTATGAGCTACCGTCCCAATCTCGTAAAGAGCTGACCCAATGCCTGATTACTCGCTCGATGGTGGA
ACAGCGGTCGACGGCTGAGTTGTTGGTGCATCCTTCCGCCATCTCGACCCCAGAATCTGCATAA

Upstream 100 bases:

>100_bases
AGAAGAGGCACAAAAATATGGTTTGATTGATCAAGTCCTCACTAGACAAAATCTTCCTAACCACTCTGAAGCCGTCAGTG
AAGTCCACTAAGAGAAAGCC

Downstream 100 bases:

>100_bases
GTTCGTTTCGGTCACATTTATTTCATGCCTCAGGCTCTCATTCGCGGTCATGATCACTACTATGAATGGGTGACGCAAGA
CCCTCGTCAGTTGAGATCTG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDTASSMPAASRAPVAERKRSQSAPLSLNQIPK
PRDIKSYLDEHVIGQDEAKKVLSVAVYNHYKRLSISQASADSVAELDDAIELQKSNILLIGPTGCGKTLLAQTLAQMLDV
PFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLDKIIEQRTGKKAMGFIQDGELRAKEQRTADMLRDLEAEDLVKFG
MIPEFTGRIPVMSVIDALDEDVLCQILTEPRNALVKQYQKLLRMDRVELEFQPDAIRAIAQEAYRRRTGARALRAIVEEI
MLDVMYELPSQSRKELTQCLITRSMVEQRSTAELLVHPSAISTPESA

Sequences:

>Translated_447_residues
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDTASSMPAASRAPVAERKRSQSAPLSLNQIPK
PRDIKSYLDEHVIGQDEAKKVLSVAVYNHYKRLSISQASADSVAELDDAIELQKSNILLIGPTGCGKTLLAQTLAQMLDV
PFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLDKIIEQRTGKKAMGFIQDGELRAKEQRTADMLRDLEAEDLVKFG
MIPEFTGRIPVMSVIDALDEDVLCQILTEPRNALVKQYQKLLRMDRVELEFQPDAIRAIAQEAYRRRTGARALRAIVEEI
MLDVMYELPSQSRKELTQCLITRSMVEQRSTAELLVHPSAISTPESA
>Mature_446_residues
SKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDTASSMPAASRAPVAERKRSQSAPLSLNQIPKP
RDIKSYLDEHVIGQDEAKKVLSVAVYNHYKRLSISQASADSVAELDDAIELQKSNILLIGPTGCGKTLLAQTLAQMLDVP
FAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKMLEGTV
ANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLDKIIEQRTGKKAMGFIQDGELRAKEQRTADMLRDLEAEDLVKFGM
IPEFTGRIPVMSVIDALDEDVLCQILTEPRNALVKQYQKLLRMDRVELEFQPDAIRAIAQEAYRRRTGARALRAIVEEIM
LDVMYELPSQSRKELTQCLITRSMVEQRSTAELLVHPSAISTPESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=306, Percent_Identity=52.2875816993464, Blast_Score=311, Evalue=1e-84,
Organism=Escherichia coli, GI1786642, Length=430, Percent_Identity=57.4418604651163, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1790366, Length=111, Percent_Identity=42.3423423423423, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=300, Percent_Identity=46, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=300, Percent_Identity=46, Blast_Score=271, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=39.3401015228426, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=39.2156862745098, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=444, Percent_Identity=38.5135135135135, Blast_Score=266, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=48.125, Blast_Score=294, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=48.125, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_ACAM1 (B0C146)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517760.1
- ProteinModelPortal:   B0C146
- GeneID:   5682258
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_3450
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   AMAR329726:AM1_3450-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 49540; Mature: 49409

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDTASSMPAASRA
CCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVAERKRSQSAPLSLNQIPKPRDIKSYLDEHVIGQDEAKKVLSVAVYNHYKRLSISQASA
CHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
DSVAELDDAIELQKSNILLIGPTGCGKTLLAQTLAQMLDVPFAVADATTLTEAGYVGEDV
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHH
ENILLRLLQVADLDVEEAQRGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKMLEGT
HHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
VANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLDKIIEQRTGKKAMGFIQDGELRAK
HCCCCCCCCCCCCHHHHHEECCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
EQRTADMLRDLEAEDLVKFGMIPEFTGRIPVMSVIDALDEDVLCQILTEPRNALVKQYQK
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHH
LLRMDRVELEFQPDAIRAIAQEAYRRRTGARALRAIVEEIMLDVMYELPSQSRKELTQCL
HHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ITRSMVEQRSTAELLVHPSAISTPESA
HHHHHHHHCCCHHHEECCCCCCCCCCC
>Mature Secondary Structure 
SKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDTASSMPAASRA
CCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVAERKRSQSAPLSLNQIPKPRDIKSYLDEHVIGQDEAKKVLSVAVYNHYKRLSISQASA
CHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
DSVAELDDAIELQKSNILLIGPTGCGKTLLAQTLAQMLDVPFAVADATTLTEAGYVGEDV
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHH
ENILLRLLQVADLDVEEAQRGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKMLEGT
HHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
VANVPPQGGRKHPYQDCIQIDTTNILFICGGAFVGLDKIIEQRTGKKAMGFIQDGELRAK
HCCCCCCCCCCCCHHHHHEECCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
EQRTADMLRDLEAEDLVKFGMIPEFTGRIPVMSVIDALDEDVLCQILTEPRNALVKQYQK
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHH
LLRMDRVELEFQPDAIRAIAQEAYRRRTGARALRAIVEEIMLDVMYELPSQSRKELTQCL
HHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ITRSMVEQRSTAELLVHPSAISTPESA
HHHHHHHHCCCHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA