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The map label for this gene is asd [H]

Identifier: 158336583

GI number: 158336583

Start: 3475766

End: 3476806

Strand: Reverse

Name: asd [H]

Synonym: AM1_3447

Alternate gene names: 158336583

Gene position: 3476806-3475766 (Counterclockwise)

Preceding gene: 158336590

Following gene: 158336582

Centisome position: 53.46

GC content: 47.93

Gene sequence:

>1041_bases
TTGGGTCAAGCATACAGAGTAGCCATATTAGGGGCCACGGGAGCAGTGGGTGCAGAGCTCATCACCCTACTAGAAGAACG
GAATTTCCCGCTATCCACCCTCAAACTCTTAGCATCTCCTCGCTCAGCTGGGCAAACCCTTACATTTAAGGGAGAAACCA
TTCAGGTTGAAGAGGTTAGCGAAGCGGCTTTTCAGGGTATTGATATAGTCCTAGCTTCAGCCGGTGGAAGCGTTTCTAAA
GCTTGGGCACCCAAGGCAGTGAAGGCTGGAGCAGTCGTTGTTGATAATTCCAGCGCCTATCGTATGGATCCTCAGGTTCC
TTTAATCGTGCCTGAAGTCAATCCCGATGCGGTGACTCAACATCAAGGGATTATTGCCAATCCTAATTGCACTACTATTC
TGATGAATGTTGTGGTTTGGCCTTTACACCAATTGCAACCTGTACAACGAATTCTGGCTGCCACCTACCAGTCTGCCAGT
GGCGCTGGCGCGCGGGCTATGGAAGAAGTTAAAGTCCAAGCCCAAGCAATCTTGAACGATGATCCCCCTCCCACCGAAAT
CTTTCCTTATCCCCTCGCATTCAACCTATTTCCGCACAATTCTGATCTGAATGCGAATGGTTATTGCACAGAAGAGATGA
AAATGGTGCAAGAAACTCGCAAGATTTTTAACGCACCTGACTTAAGAGTATCTGTTACCTGTGTCCGCGTCCCAGTCCTT
AGAGCACATTCAGAAGCTATTAATCTTGAGTTTTCCCAACCTTTTCCAATTGAGAAGGCCCGGACAATTCTACAGGATTC
TCCAGGGGTTAAGTTAGTTGAAGACTGGCAAGCCAATTATTTTCCGATGCCCATCGATGCAAGCGGGCAAGACGACGTTT
TAGTGGGCCGCATCCGTCAAGATATTTCCCATGCCAACGGCCTAGAGTTGTGGTTAAGCGGCGACCAAATTCGCAAAGGA
GCAGCTTTAAATGCTGTCCAAATTGCAGAATTACTGGTAGAACGACAACTCTTAAAACCCGCTGCTGTAGCATCTGCCTA
A

Upstream 100 bases:

>100_bases
CCAAACCTTTCTAAAATCAACTTTCTTAGATCACTATCTTGAACTTACACATCCAATTATTTATTTAGCCCTTTAATTAC
AGACGTTGGAGGAATCGAAT

Downstream 100 bases:

>100_bases
CCGTTTACCCTGCTTTCATAGGACCGCGCTAATTCATAGCCAAAAACTAGAATAAAGTCTCAATTCAACTACGCATCACC
CCTATGAAAGCGGTAAGAGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGQAYRVAILGATGAVGAELITLLEERNFPLSTLKLLASPRSAGQTLTFKGETIQVEEVSEAAFQGIDIVLASAGGSVSK
AWAPKAVKAGAVVVDNSSAYRMDPQVPLIVPEVNPDAVTQHQGIIANPNCTTILMNVVVWPLHQLQPVQRILAATYQSAS
GAGARAMEEVKVQAQAILNDDPPPTEIFPYPLAFNLFPHNSDLNANGYCTEEMKMVQETRKIFNAPDLRVSVTCVRVPVL
RAHSEAINLEFSQPFPIEKARTILQDSPGVKLVEDWQANYFPMPIDASGQDDVLVGRIRQDISHANGLELWLSGDQIRKG
AALNAVQIAELLVERQLLKPAAVASA

Sequences:

>Translated_346_residues
MGQAYRVAILGATGAVGAELITLLEERNFPLSTLKLLASPRSAGQTLTFKGETIQVEEVSEAAFQGIDIVLASAGGSVSK
AWAPKAVKAGAVVVDNSSAYRMDPQVPLIVPEVNPDAVTQHQGIIANPNCTTILMNVVVWPLHQLQPVQRILAATYQSAS
GAGARAMEEVKVQAQAILNDDPPPTEIFPYPLAFNLFPHNSDLNANGYCTEEMKMVQETRKIFNAPDLRVSVTCVRVPVL
RAHSEAINLEFSQPFPIEKARTILQDSPGVKLVEDWQANYFPMPIDASGQDDVLVGRIRQDISHANGLELWLSGDQIRKG
AALNAVQIAELLVERQLLKPAAVASA
>Mature_345_residues
GQAYRVAILGATGAVGAELITLLEERNFPLSTLKLLASPRSAGQTLTFKGETIQVEEVSEAAFQGIDIVLASAGGSVSKA
WAPKAVKAGAVVVDNSSAYRMDPQVPLIVPEVNPDAVTQHQGIIANPNCTTILMNVVVWPLHQLQPVQRILAATYQSASG
AGARAMEEVKVQAQAILNDDPPPTEIFPYPLAFNLFPHNSDLNANGYCTEEMKMVQETRKIFNAPDLRVSVTCVRVPVLR
AHSEAINLEFSQPFPIEKARTILQDSPGVKLVEDWQANYFPMPIDASGQDDVLVGRIRQDISHANGLELWLSGDQIRKGA
ALNAVQIAELLVERQLLKPAAVASA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:
GO:0003942: Aspartate-semialdehyde dehydrogenase
GO:0004073: Aspartate-semialdehyde dehydrogenase
GO:0005488: Aspartate-semialdehyde dehydrogenase
GO:0005737: Aspartate-semialdehyde dehydrogenase
GO:0006520: Aspartate-semialdehyde dehydrogenase
GO:0008652: Aspartate-semialdehyde dehydrogenase
GO:0009086: Aspartate-semialdehyde dehydrogenase
GO:0009088: Aspartate-semialdehyde dehydrogenase
GO:0009089: Aspartate-semialdehyde dehydrogenase
GO:0009097: Aspartate-semialdehyde dehydrogenase
GO:0016620: Aspartate-semialdehyde dehydrogenase
GO:0046983: Aspartate-semialdehyde dehydrogenase
GO:0050661: Aspartate-semialdehyde dehydrogenase
GO:0051287: Aspartate-semialdehyde dehydrogenase
GO:0055114: Aspartate-semialdehyde dehydrogenase

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=35.1906158357771, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1789841, Length=353, Percent_Identity=28.6118980169972, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37330; Mature: 37199

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQAYRVAILGATGAVGAELITLLEERNFPLSTLKLLASPRSAGQTLTFKGETIQVEEVS
CCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCEEEHHHHH
EAAFQGIDIVLASAGGSVSKAWAPKAVKAGAVVVDNSSAYRMDPQVPLIVPEVNPDAVTQ
HHHHCCEEEEEEECCCCCCHHCCCCHHCCCEEEEECCCCEEECCCCCEEEECCCCCHHHC
HQGIIANPNCTTILMNVVVWPLHQLQPVQRILAATYQSASGAGARAMEEVKVQAQAILND
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
DPPPTEIFPYPLAFNLFPHNSDLNANGYCTEEMKMVQETRKIFNAPDLRVSVTCVRVPVL
CCCCCCEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHH
RAHSEAINLEFSQPFPIEKARTILQDSPGVKLVEDWQANYFPMPIDASGQDDVLVGRIRQ
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
DISHANGLELWLSGDQIRKGAALNAVQIAELLVERQLLKPAAVASA
HHCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
GQAYRVAILGATGAVGAELITLLEERNFPLSTLKLLASPRSAGQTLTFKGETIQVEEVS
CCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCEEEHHHHH
EAAFQGIDIVLASAGGSVSKAWAPKAVKAGAVVVDNSSAYRMDPQVPLIVPEVNPDAVTQ
HHHHCCEEEEEEECCCCCCHHCCCCHHCCCEEEEECCCCEEECCCCCEEEECCCCCHHHC
HQGIIANPNCTTILMNVVVWPLHQLQPVQRILAATYQSASGAGARAMEEVKVQAQAILND
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
DPPPTEIFPYPLAFNLFPHNSDLNANGYCTEEMKMVQETRKIFNAPDLRVSVTCVRVPVL
CCCCCCEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHH
RAHSEAINLEFSQPFPIEKARTILQDSPGVKLVEDWQANYFPMPIDASGQDDVLVGRIRQ
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
DISHANGLELWLSGDQIRKGAALNAVQIAELLVERQLLKPAAVASA
HHCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]