Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 158336574

GI number: 158336574

Start: 3468003

End: 3469718

Strand: Direct

Name: hflX [H]

Synonym: AM1_3438

Alternate gene names: 158336574

Gene position: 3468003-3469718 (Clockwise)

Preceding gene: 158336573

Following gene: 158336575

Centisome position: 53.32

GC content: 51.98

Gene sequence:

>1716_bases
TTGGCAAGGCAAGGAAGACTTATCGAAACGATTTACGGTAATCTCAAAGGCTTAAAATCTAATCAAATCAAGCAGCTGCG
GCGACTCTACCATCAGCGACTTCCGAGTGATCGCATCACGACGTCTGACTTTGCCCAGCGATTAGCTGCCATCAGTACGG
ATATTCATCAGCCCATCAGCACCTATCTCAACCGTCGTGGCCAGGTGATTCGGGTGGGTGTGGGGTCTCCCCGGCAAACC
CAAATCCCCCCGTTAGAATTGCCTCGATATGGTGCAGATCGCTTGAGCGGCATTCGCTGTGTTGCCACCACCCTTAAACA
AGAGGTCCCCAAGGAGTCTGCATTAACGGCGATGGCCTTACAGCGCTTAGATGCTTTGGCCGTCCTTACCATGACGGGCT
CTGGTTTTGAGCGGCGCGGTGGTGGAGCCACGGGATATGTTCGGTCGACCTACCTGGCTCATCTCGTGCCTGATCCAACC
ACCCCTTGGACCATTTCTTCCCCGTTGAGTCTCGAACAGTTGGCTCAACAGAATTTGATGGATTTGGTGGAAGCCTTAGA
GTCTGAATTTGGACGCTCTCTGAACCCTCGCTTGTCAGAGACAGCTGAAACTGAGCAGGTGTTAATGGTTGGGGTGATTC
CTCAAGCCGTCTCTAAAGCAGAGATGAAGGCTAATTTAGCAGAGGTGGCGCTCTTAGTGGAGAGTGCTGGCGGAGTCGTG
GTAGAGACGATTCACCAGAAGCGGTCTCATCCCCATCCCCAAACGGTTGTGGGAGCCGGTAAAGTCAAGGAAATTGCCCT
AAGGGCCCAAACCTTAGGGGTGACGCTAATTGTTTTTAATCTAGATCTTTCCCCGTCTCAGGTGCGTAATTTAGAGACCC
AAATTGGCATTCGTATTGTCGATCGCACGGAAGTGATTTTAGATATCTTTGCCCAGCGAGCCCAATCCCAGGCGGGCAAA
TTACAGGTGGAACTCGCGCAATTGGAATACATGCTGCCGCGATTGGCAGGGCGAGGCCAAGCCATGTCTCGCCTTGGGGG
TGGTATTGGTACTCGAGGACCGGGAGAAACGAAGCTGGAAACAGAACGACGAGCCATTCAACGCCGAATCAATACCTTGC
AACAGGCGGTCAACCAGCTCCAGGCTCACCGTTCCCGTCTGCGTCAACGTCGTCAGCATCAGCGAGTTCCGTCCGTTGCT
GTGGTGGGCTATACCAATGCCGGCAAGTCGACCCTGCTGAATGTGTTGACCAACGCCGAAGCTTATACGGCCGATCAGCT
CTTTGCCACCCTCGACCCTACGACCCGTCGCCTTAGTATTCCCGATCCTGAAACCCATCAGATGCGGACTTTAGTACTAA
CGGATACGGTGGGATTTATTCATAATCTCCCTCCCCCGTTGATGGATGCTTTTCGAGCAACTTTGGAAGAGGTGACGGAT
GCTGACGTTTTGCTGCATGTTGTGGATTTGTCTCATCCCGATTGGGAAAATCATTTGCGATCGGTGATGGATTTGCTAGG
AACTATGCCGATTACACCGGGGCCAGGATTGATTGCCTTTAACAAGATGGATCAAGTTAGCAGTGAAGCCTTGGCGATTG
CCCAAGACCAGTTTCCCCAAGCTGTCTTTATTTCAGCGCAAGAACGCTTGGGATTGAACACTCTGCGACAAAAACTATTG
GAATTAATCGATTATGCGGCCATGCCTACGGTTTAG

Upstream 100 bases:

>100_bases
TAAGGCTCAGAAGAAATAGCCCTCATTAAGGATCGTTGACGACCATTGCCAGTTTTTTTTGGGCAACTCTACAATTGAGG
GGCAATGATGTCGTCTTGCT

Downstream 100 bases:

>100_bases
TGCTGCCCTGTTGGTTAAAGCTGCTTATTGCGTGATCGGTATCACGTTGGTCATCATCCAAGATCACTGAGTTATGGCTG
AATTGGGGGGAAACTCAATT

Product: GTP-binding protein HflX-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MARQGRLIETIYGNLKGLKSNQIKQLRRLYHQRLPSDRITTSDFAQRLAAISTDIHQPISTYLNRRGQVIRVGVGSPRQT
QIPPLELPRYGADRLSGIRCVATTLKQEVPKESALTAMALQRLDALAVLTMTGSGFERRGGGATGYVRSTYLAHLVPDPT
TPWTISSPLSLEQLAQQNLMDLVEALESEFGRSLNPRLSETAETEQVLMVGVIPQAVSKAEMKANLAEVALLVESAGGVV
VETIHQKRSHPHPQTVVGAGKVKEIALRAQTLGVTLIVFNLDLSPSQVRNLETQIGIRIVDRTEVILDIFAQRAQSQAGK
LQVELAQLEYMLPRLAGRGQAMSRLGGGIGTRGPGETKLETERRAIQRRINTLQQAVNQLQAHRSRLRQRRQHQRVPSVA
VVGYTNAGKSTLLNVLTNAEAYTADQLFATLDPTTRRLSIPDPETHQMRTLVLTDTVGFIHNLPPPLMDAFRATLEEVTD
ADVLLHVVDLSHPDWENHLRSVMDLLGTMPITPGPGLIAFNKMDQVSSEALAIAQDQFPQAVFISAQERLGLNTLRQKLL
ELIDYAAMPTV

Sequences:

>Translated_571_residues
MARQGRLIETIYGNLKGLKSNQIKQLRRLYHQRLPSDRITTSDFAQRLAAISTDIHQPISTYLNRRGQVIRVGVGSPRQT
QIPPLELPRYGADRLSGIRCVATTLKQEVPKESALTAMALQRLDALAVLTMTGSGFERRGGGATGYVRSTYLAHLVPDPT
TPWTISSPLSLEQLAQQNLMDLVEALESEFGRSLNPRLSETAETEQVLMVGVIPQAVSKAEMKANLAEVALLVESAGGVV
VETIHQKRSHPHPQTVVGAGKVKEIALRAQTLGVTLIVFNLDLSPSQVRNLETQIGIRIVDRTEVILDIFAQRAQSQAGK
LQVELAQLEYMLPRLAGRGQAMSRLGGGIGTRGPGETKLETERRAIQRRINTLQQAVNQLQAHRSRLRQRRQHQRVPSVA
VVGYTNAGKSTLLNVLTNAEAYTADQLFATLDPTTRRLSIPDPETHQMRTLVLTDTVGFIHNLPPPLMDAFRATLEEVTD
ADVLLHVVDLSHPDWENHLRSVMDLLGTMPITPGPGLIAFNKMDQVSSEALAIAQDQFPQAVFISAQERLGLNTLRQKLL
ELIDYAAMPTV
>Mature_570_residues
ARQGRLIETIYGNLKGLKSNQIKQLRRLYHQRLPSDRITTSDFAQRLAAISTDIHQPISTYLNRRGQVIRVGVGSPRQTQ
IPPLELPRYGADRLSGIRCVATTLKQEVPKESALTAMALQRLDALAVLTMTGSGFERRGGGATGYVRSTYLAHLVPDPTT
PWTISSPLSLEQLAQQNLMDLVEALESEFGRSLNPRLSETAETEQVLMVGVIPQAVSKAEMKANLAEVALLVESAGGVVV
ETIHQKRSHPHPQTVVGAGKVKEIALRAQTLGVTLIVFNLDLSPSQVRNLETQIGIRIVDRTEVILDIFAQRAQSQAGKL
QVELAQLEYMLPRLAGRGQAMSRLGGGIGTRGPGETKLETERRAIQRRINTLQQAVNQLQAHRSRLRQRRQHQRVPSVAV
VGYTNAGKSTLLNVLTNAEAYTADQLFATLDPTTRRLSIPDPETHQMRTLVLTDTVGFIHNLPPPLMDAFRATLEEVTDA
DVLLHVVDLSHPDWENHLRSVMDLLGTMPITPGPGLIAFNKMDQVSSEALAIAQDQFPQAVFISAQERLGLNTLRQKLLE
LIDYAAMPTV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:
GO:0005525: GTP-binding protein HflX-like protein
GO:0005622: GTP-binding protein HflX-like protein

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=236, Percent_Identity=33.8983050847458, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=34.5132743362832, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=35.377358490566, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=35.377358490566, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=35.377358490566, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=35.377358490566, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1790615, Length=339, Percent_Identity=44.5427728613569, Blast_Score=262, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17561038, Length=263, Percent_Identity=31.5589353612167, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24650079, Length=318, Percent_Identity=33.6477987421384, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62914; Mature: 62783

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQGRLIETIYGNLKGLKSNQIKQLRRLYHQRLPSDRITTSDFAQRLAAISTDIHQPIS
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TYLNRRGQVIRVGVGSPRQTQIPPLELPRYGADRLSGIRCVATTLKQEVPKESALTAMAL
HHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
QRLDALAVLTMTGSGFERRGGGATGYVRSTYLAHLVPDPTTPWTISSPLSLEQLAQQNLM
HHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHH
DLVEALESEFGRSLNPRLSETAETEQVLMVGVIPQAVSKAEMKANLAEVALLVESAGGVV
HHHHHHHHHHCCCCCCCHHHHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHH
VETIHQKRSHPHPQTVVGAGKVKEIALRAQTLGVTLIVFNLDLSPSQVRNLETQIGIRIV
HHHHHHHHCCCCCCCEECCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCEEEE
DRTEVILDIFAQRAQSQAGKLQVELAQLEYMLPRLAGRGQAMSRLGGGIGTRGPGETKLE
CHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHH
TERRAIQRRINTLQQAVNQLQAHRSRLRQRRQHQRVPSVAVVGYTNAGKSTLLNVLTNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCC
AYTADQLFATLDPTTRRLSIPDPETHQMRTLVLTDTVGFIHNLPPPLMDAFRATLEEVTD
HHHHHHHHHHCCCCCCEECCCCCCCHHHEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHCC
ADVLLHVVDLSHPDWENHLRSVMDLLGTMPITPGPGLIAFNKMDQVSSEALAIAQDQFPQ
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCC
AVFISAQERLGLNTLRQKLLELIDYAAMPTV
EEEECCHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARQGRLIETIYGNLKGLKSNQIKQLRRLYHQRLPSDRITTSDFAQRLAAISTDIHQPIS
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TYLNRRGQVIRVGVGSPRQTQIPPLELPRYGADRLSGIRCVATTLKQEVPKESALTAMAL
HHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
QRLDALAVLTMTGSGFERRGGGATGYVRSTYLAHLVPDPTTPWTISSPLSLEQLAQQNLM
HHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHH
DLVEALESEFGRSLNPRLSETAETEQVLMVGVIPQAVSKAEMKANLAEVALLVESAGGVV
HHHHHHHHHHCCCCCCCHHHHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHH
VETIHQKRSHPHPQTVVGAGKVKEIALRAQTLGVTLIVFNLDLSPSQVRNLETQIGIRIV
HHHHHHHHCCCCCCCEECCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCEEEE
DRTEVILDIFAQRAQSQAGKLQVELAQLEYMLPRLAGRGQAMSRLGGGIGTRGPGETKLE
CHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHH
TERRAIQRRINTLQQAVNQLQAHRSRLRQRRQHQRVPSVAVVGYTNAGKSTLLNVLTNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCC
AYTADQLFATLDPTTRRLSIPDPETHQMRTLVLTDTVGFIHNLPPPLMDAFRATLEEVTD
HHHHHHHHHHCCCCCCEECCCCCCCHHHEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHCC
ADVLLHVVDLSHPDWENHLRSVMDLLGTMPITPGPGLIAFNKMDQVSSEALAIAQDQFPQ
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCC
AVFISAQERLGLNTLRQKLLELIDYAAMPTV
EEEECCHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]