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The map label for this gene is ndhD [H]

Identifier: 158336337

GI number: 158336337

Start: 3238963

End: 3240393

Strand: Direct

Name: ndhD [H]

Synonym: AM1_3199

Alternate gene names: 158336337

Gene position: 3238963-3240393 (Clockwise)

Preceding gene: 158336336

Following gene: 158336338

Centisome position: 49.8

GC content: 51.29

Gene sequence:

>1431_bases
ATGAATACCCTAACGATTATTTGGATAGCCCTGCCGTTTTTCGTGGGGTTTGTAGGGTATCTGGTCCCTAAGGTTGATCG
ATACTTAGCCTTGGCCATGACCTTAGTGTCTGCCAGCTATGCCGCTCGAGTGTTGATGGAATCAACGCCGCTGACGGTAG
AGCTGATGGATAACTTTGGGGTCACCCTCCAGATTGATAGTCTGAGTGGCTACTTTATCTTGACCAATGCCCTAGTTACG
GCTGCCGTGATTTGCTATTGCTGGGGGACAGGAAAATCCGCATTTTTTTATACCCAGACCATTATTCTGCATGGCAGCGT
CAATGCCGTCTTTATTTGCGCCGACTTTATTAGTTTATATGTCGCCTTAGAGGTGATTGGCATTGCCGCCTTCTTGTTGG
TGTCCTACCCGCGTACGAATCGGGCGATTTGGGTGGCCCTGCGCTACCTGTTTATCAGCAATACGGCCATGCTGTTTTAT
TTGGTGGGCGCTGTGTTGGTGTACCAAGCCAACAACTCCTTTGCTTTTGCGGGCTTGGAAAAGGCACCCCCAGAAGCCCT
AGCCCTGATTTTCTTGGGACTGTTGACCAAAGGCGGCATATTTGTATCAGGGTTGTGGTTACCCTTAACCCATTCCGAGT
CCGAAACCCCTGTCTCTGCCCTACTCTCCGGCGTTGTGGTCAAAACCGGGGTCTTTCCTTTGGCTCGGATGGCCTTAATG
GTGGATACAGTCGCCCCAGTGATCACCCTATTTGGGATTGGCACTGCCTTTTTGGGGATTAGCTTGGCTCTCTTTGAGCA
AGACACCAAGCGACTTTTGGCCCAAAGCACTATTTCTCAGCTTGGATTTATCCTGGCTGCCCCGGCTGTGGGTGGGTTCT
ATGCCTTGACTCACGGTTTGGTGAAAGCCACCCTCTTTTTAACCGCAGGCACCTTGCCTAGCCGAGATTTTCAGGAACTG
CATAAGCAGCCAATCCCACGATCCCTATGGCTAGTCCTGTTGATGGCCAGCTGCTCTATCTCCGGTCTTCCCCTCTGGGC
TGGGTTTGCCTCTAAGGCATTAACCCTAAAAAGTCTGCTGCCTTGGCAAATGCTCGCCCTCAATATTGCCACCGTAGGCA
CCGTGGCCACCTTTGCCAAATTTATCTTTTTGCCCCATCAAAGGGGCTCCAAGTCGATTCGAACTGGATTTTGGGTGGCG
GTGCTGCTGCTGTTGGGGGGCTTACTGGCGGCCAATGGTGCTTATTACCAGGCCTATACCGTGGCCAATATCGGTAAAGC
TTTAGCGAAGGTGGCAATTGGCTGGTTGGTCTATTGGCTAGTGATTCGACGGGTAGTGCTGAAACTGCCACGGGTGCAGG
AGCAGCTCGAACATTTAATTGGGGGGATGAGCTTAATGTTGGTTCTATTGTTCTGGATGGTGTTGGCATGA

Upstream 100 bases:

>100_bases
TTGGGTTTTCAATTCAAGCGTTGATGCTGGTGGGCGTCATGAAGCTCTCCCGCGACAATCCCACCTTGGAAAGCCGTGAG
ATTGAAAAGACCTACACACC

Downstream 100 bases:

>100_bases
CTGGATATCTGAATATTCTGCTGCGTTTAGCCATCTGGTTTTTGCTAACCGCCGATTTTGGTATTGCCAATACCATCATT
GGCGTCTGTGTGGCTTTACT

Product: putative monovalent cation/H+ antiporter subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNTLTIIWIALPFFVGFVGYLVPKVDRYLALAMTLVSASYAARVLMESTPLTVELMDNFGVTLQIDSLSGYFILTNALVT
AAVICYCWGTGKSAFFYTQTIILHGSVNAVFICADFISLYVALEVIGIAAFLLVSYPRTNRAIWVALRYLFISNTAMLFY
LVGAVLVYQANNSFAFAGLEKAPPEALALIFLGLLTKGGIFVSGLWLPLTHSESETPVSALLSGVVVKTGVFPLARMALM
VDTVAPVITLFGIGTAFLGISLALFEQDTKRLLAQSTISQLGFILAAPAVGGFYALTHGLVKATLFLTAGTLPSRDFQEL
HKQPIPRSLWLVLLMASCSISGLPLWAGFASKALTLKSLLPWQMLALNIATVGTVATFAKFIFLPHQRGSKSIRTGFWVA
VLLLLGGLLAANGAYYQAYTVANIGKALAKVAIGWLVYWLVIRRVVLKLPRVQEQLEHLIGGMSLMLVLLFWMVLA

Sequences:

>Translated_476_residues
MNTLTIIWIALPFFVGFVGYLVPKVDRYLALAMTLVSASYAARVLMESTPLTVELMDNFGVTLQIDSLSGYFILTNALVT
AAVICYCWGTGKSAFFYTQTIILHGSVNAVFICADFISLYVALEVIGIAAFLLVSYPRTNRAIWVALRYLFISNTAMLFY
LVGAVLVYQANNSFAFAGLEKAPPEALALIFLGLLTKGGIFVSGLWLPLTHSESETPVSALLSGVVVKTGVFPLARMALM
VDTVAPVITLFGIGTAFLGISLALFEQDTKRLLAQSTISQLGFILAAPAVGGFYALTHGLVKATLFLTAGTLPSRDFQEL
HKQPIPRSLWLVLLMASCSISGLPLWAGFASKALTLKSLLPWQMLALNIATVGTVATFAKFIFLPHQRGSKSIRTGFWVA
VLLLLGGLLAANGAYYQAYTVANIGKALAKVAIGWLVYWLVIRRVVLKLPRVQEQLEHLIGGMSLMLVLLFWMVLA
>Mature_476_residues
MNTLTIIWIALPFFVGFVGYLVPKVDRYLALAMTLVSASYAARVLMESTPLTVELMDNFGVTLQIDSLSGYFILTNALVT
AAVICYCWGTGKSAFFYTQTIILHGSVNAVFICADFISLYVALEVIGIAAFLLVSYPRTNRAIWVALRYLFISNTAMLFY
LVGAVLVYQANNSFAFAGLEKAPPEALALIFLGLLTKGGIFVSGLWLPLTHSESETPVSALLSGVVVKTGVFPLARMALM
VDTVAPVITLFGIGTAFLGISLALFEQDTKRLLAQSTISQLGFILAAPAVGGFYALTHGLVKATLFLTAGTLPSRDFQEL
HKQPIPRSLWLVLLMASCSISGLPLWAGFASKALTLKSLLPWQMLALNIATVGTVATFAKFIFLPHQRGSKSIRTGFWVA
VLLLLGGLLAANGAYYQAYTVANIGKALAKVAIGWLVYWLVIRRVVLKLPRVQEQLEHLIGGMSLMLVLLFWMVLA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:
GO:0006120: NAD(P)H-quinone oxidoreductase chain 4
GO:0008137: NAD(P)H-quinone oxidoreductase chain 4
GO:0009579: NAD(P)H-quinone oxidoreductase chain 4
GO:0016020: NAD(P)H-quinone oxidoreductase chain 4
GO:0016021: NAD(P)H-quinone oxidoreductase chain 4
GO:0016491: NAD(P)H-quinone oxidoreductase chain 4
GO:0016655: NAD(P)H-quinone oxidoreductase chain 4
GO:0042651: NAD(P)H-quinone oxidoreductase chain 4
GO:0042773: NAD(P)H-quinone oxidoreductase chain 4
GO:0048038: NAD(P)H-quinone oxidoreductase chain 4
GO:0055114: NAD(P)H-quinone oxidoreductase chain 4

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788827, Length=347, Percent_Identity=29.971181556196, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788831, Length=313, Percent_Identity=26.8370607028754, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788829, Length=335, Percent_Identity=28.955223880597, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788614, Length=294, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788613, Length=359, Percent_Identity=26.1838440111421, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51624; Mature: 51624

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLTIIWIALPFFVGFVGYLVPKVDRYLALAMTLVSASYAARVLMESTPLTVELMDNFG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
VTLQIDSLSGYFILTNALVTAAVICYCWGTGKSAFFYTQTIILHGSVNAVFICADFISLY
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCCEEHHHHHHHHHH
VALEVIGIAAFLLVSYPRTNRAIWVALRYLFISNTAMLFYLVGAVLVYQANNSFAFAGLE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCC
KAPPEALALIFLGLLTKGGIFVSGLWLPLTHSESETPVSALLSGVVVKTGVFPLARMALM
CCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHH
VDTVAPVITLFGIGTAFLGISLALFEQDTKRLLAQSTISQLGFILAAPAVGGFYALTHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VKATLFLTAGTLPSRDFQELHKQPIPRSLWLVLLMASCSISGLPLWAGFASKALTLKSLL
HHHHHHHEECCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PWQMLALNIATVGTVATFAKFIFLPHQRGSKSIRTGFWVAVLLLLGGLLAANGAYYQAYT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
VANIGKALAKVAIGWLVYWLVIRRVVLKLPRVQEQLEHLIGGMSLMLVLLFWMVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTLTIIWIALPFFVGFVGYLVPKVDRYLALAMTLVSASYAARVLMESTPLTVELMDNFG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
VTLQIDSLSGYFILTNALVTAAVICYCWGTGKSAFFYTQTIILHGSVNAVFICADFISLY
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCCEEHHHHHHHHHH
VALEVIGIAAFLLVSYPRTNRAIWVALRYLFISNTAMLFYLVGAVLVYQANNSFAFAGLE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCC
KAPPEALALIFLGLLTKGGIFVSGLWLPLTHSESETPVSALLSGVVVKTGVFPLARMALM
CCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHH
VDTVAPVITLFGIGTAFLGISLALFEQDTKRLLAQSTISQLGFILAAPAVGGFYALTHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VKATLFLTAGTLPSRDFQELHKQPIPRSLWLVLLMASCSISGLPLWAGFASKALTLKSLL
HHHHHHHEECCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PWQMLALNIATVGTVATFAKFIFLPHQRGSKSIRTGFWVAVLLLLGGLLAANGAYYQAYT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
VANIGKALAKVAIGWLVYWLVIRRVVLKLPRVQEQLEHLIGGMSLMLVLLFWMVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA