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The map label for this gene is lpxB [H]

Identifier: 158336303

GI number: 158336303

Start: 3194536

End: 3195819

Strand: Direct

Name: lpxB [H]

Synonym: AM1_3166

Alternate gene names: 158336303

Gene position: 3194536-3195819 (Clockwise)

Preceding gene: 158336297

Following gene: 158336306

Centisome position: 49.12

GC content: 51.95

Gene sequence:

>1284_bases
ATGGCCGAAGCTTTGGCCGATCTCGTTATTCTCAGCAATGGCCCTGGTGAACTCTCCACTTGGGTCCGCCCTGTACTGCA
AGTGTTGAGCAGGCGACCACAGTTTAGTCGAGTCTCCATCCTTCTCTCCCCCTGTCCCCATGCTGGGGGACATGAGCAGG
CCGTTGCGGAAACCTTCCCTGGAGTGGATCGCGTGTTAGAACCACAGCAGTTTTTCCAGTTTCTGCTCTGGGGTCAAACC
CCTGATGCCTGGCACTGGCATCCCCAAGGCGTGGTGGTTTTCTTGGGCGGCGATCAGTTCTATGCGGTGGCGATTGGTAA
GCGGCTAGGCTATCGCATCGTTACCTATGCTGAATGGACGCCCCGTTGGTTACCTTGGATAGACTACTGCGGAGTGGCTC
AGCCTCAAACGCTACAAAAAGTCCCACGTCGATATCGCTCCAAGGTAACGGTAGTGGGTAATTTGATGACCGATATTCAA
TCAAGTGTCGGTTCTGACGCATTGTTAGATCAGTTAGGGTGGGCTCCAGACACTGAAATAATTGGGCTATTGCCAGGATC
AAAACCTGCCAAATTAAGGATAGGGGTACCATTTTGCTTAGCTGTTGCAGAGCGACTCCAGCAACATCGACCCCAATCAC
AATTCATCATTCCCCTAGCCCCAGGGCTGTCCTATACAACCCTATCTCGCTATGCTTGCGCCAGCGATAACCCGCTGATT
GCAACCTATTTAGGGAACTCTGCTACTTTAGTGCAATCAAATGAGGAACTTCCTTATCTCTGCACCCCACGGGGCACGAA
AGTCTGGCTTTGGCTGCCCAGTCCTGCCTATGATGTGCTGATGCATTGTCAAATTTGCCTAACCACCTTGGGGGCCAATA
CGGCTGAATTGACAGCTTTAATGGTACCAATGATGGTAATTCTGCCGACCCAACATCTGGCTGGCGCACCCATTGGAGAA
GGTTTGTTAGGCGTACTGGCTCGCCTATCTTTTGTCGGCGCAGCCATGAACCGCTTCATTCTGCCCCAAGGCTTTAAAGC
TTGGCCGAATATTTGGGCCGACCAAGAAATTGTGCCGGAATGGGTAGGACCTTTATCTTCTGAATTAGTGGCTCACTATT
TGCAGGCCCTCTTAGCCTCTCCATCCAGACTGCAAGCTATCAAAGCAGCTCTAAGAGAGGTGCGAGGTGAAGTGGGTGCC
GTAGCGCGATTTGCTCAGCTAGTGTCAGAAACGCTAATAAAAGAGAGGGGGGCTGAAGCGCTTGTGATTCGGGATGCCCC
TTAA

Upstream 100 bases:

>100_bases
TGTTCAGAGAACGCCGCCATGCTAATTCGTAAATTTTTTTAATATTGCTTAATCATTTCTTTATTGTGACATTTCTGCTG
CACTTCCGCAGGTTTATCTG

Downstream 100 bases:

>100_bases
GAATCTTGGGATTGGCCATCGCGACGGCCTAATTCGTAGACGCCACCGATCAGCAAACAAATCATGCCTAGGCTGACCCC
CCAGCTACGACCTCCAAAGC

Product: lipid-A-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MAEALADLVILSNGPGELSTWVRPVLQVLSRRPQFSRVSILLSPCPHAGGHEQAVAETFPGVDRVLEPQQFFQFLLWGQT
PDAWHWHPQGVVVFLGGDQFYAVAIGKRLGYRIVTYAEWTPRWLPWIDYCGVAQPQTLQKVPRRYRSKVTVVGNLMTDIQ
SSVGSDALLDQLGWAPDTEIIGLLPGSKPAKLRIGVPFCLAVAERLQQHRPQSQFIIPLAPGLSYTTLSRYACASDNPLI
ATYLGNSATLVQSNEELPYLCTPRGTKVWLWLPSPAYDVLMHCQICLTTLGANTAELTALMVPMMVILPTQHLAGAPIGE
GLLGVLARLSFVGAAMNRFILPQGFKAWPNIWADQEIVPEWVGPLSSELVAHYLQALLASPSRLQAIKAALREVRGEVGA
VARFAQLVSETLIKERGAEALVIRDAP

Sequences:

>Translated_427_residues
MAEALADLVILSNGPGELSTWVRPVLQVLSRRPQFSRVSILLSPCPHAGGHEQAVAETFPGVDRVLEPQQFFQFLLWGQT
PDAWHWHPQGVVVFLGGDQFYAVAIGKRLGYRIVTYAEWTPRWLPWIDYCGVAQPQTLQKVPRRYRSKVTVVGNLMTDIQ
SSVGSDALLDQLGWAPDTEIIGLLPGSKPAKLRIGVPFCLAVAERLQQHRPQSQFIIPLAPGLSYTTLSRYACASDNPLI
ATYLGNSATLVQSNEELPYLCTPRGTKVWLWLPSPAYDVLMHCQICLTTLGANTAELTALMVPMMVILPTQHLAGAPIGE
GLLGVLARLSFVGAAMNRFILPQGFKAWPNIWADQEIVPEWVGPLSSELVAHYLQALLASPSRLQAIKAALREVRGEVGA
VARFAQLVSETLIKERGAEALVIRDAP
>Mature_426_residues
AEALADLVILSNGPGELSTWVRPVLQVLSRRPQFSRVSILLSPCPHAGGHEQAVAETFPGVDRVLEPQQFFQFLLWGQTP
DAWHWHPQGVVVFLGGDQFYAVAIGKRLGYRIVTYAEWTPRWLPWIDYCGVAQPQTLQKVPRRYRSKVTVVGNLMTDIQS
SVGSDALLDQLGWAPDTEIIGLLPGSKPAKLRIGVPFCLAVAERLQQHRPQSQFIIPLAPGLSYTTLSRYACASDNPLIA
TYLGNSATLVQSNEELPYLCTPRGTKVWLWLPSPAYDVLMHCQICLTTLGANTAELTALMVPMMVILPTQHLAGAPIGEG
LLGVLARLSFVGAAMNRFILPQGFKAWPNIWADQEIVPEWVGPLSSELVAHYLQALLASPSRLQAIKAALREVRGEVGAV
ARFAQLVSETLIKERGAEALVIRDAP

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835 [H]

Pfam domain/function: PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 46860; Mature: 46729

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEALADLVILSNGPGELSTWVRPVLQVLSRRPQFSRVSILLSPCPHAGGHEQAVAETFP
CCHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCC
GVDRVLEPQQFFQFLLWGQTPDAWHWHPQGVVVFLGGDQFYAVAIGKRLGYRIVTYAEWT
CHHHHCCHHHHHHHHHCCCCCCCCEECCCCEEEEECCCEEEEEEEHHHCCCEEEEEECCC
PRWLPWIDYCGVAQPQTLQKVPRRYRSKVTVVGNLMTDIQSSVGSDALLDQLGWAPDTEI
CCCCCHHHHCCCCCCHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
IGLLPGSKPAKLRIGVPFCLAVAERLQQHRPQSQFIIPLAPGLSYTTLSRYACASDNPLI
EEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCEE
ATYLGNSATLVQSNEELPYLCTPRGTKVWLWLPSPAYDVLMHCQICLTTLGANTAELTAL
EEEECCCEEEEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHH
MVPMMVILPTQHLAGAPIGEGLLGVLARLSFVGAAMNRFILPQGFKAWPNIWADQEIVPE
HHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
WVGPLSSELVAHYLQALLASPSRLQAIKAALREVRGEVGAVARFAQLVSETLIKERGAEA
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVIRDAP
EEEECCC
>Mature Secondary Structure 
AEALADLVILSNGPGELSTWVRPVLQVLSRRPQFSRVSILLSPCPHAGGHEQAVAETFP
CHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCC
GVDRVLEPQQFFQFLLWGQTPDAWHWHPQGVVVFLGGDQFYAVAIGKRLGYRIVTYAEWT
CHHHHCCHHHHHHHHHCCCCCCCCEECCCCEEEEECCCEEEEEEEHHHCCCEEEEEECCC
PRWLPWIDYCGVAQPQTLQKVPRRYRSKVTVVGNLMTDIQSSVGSDALLDQLGWAPDTEI
CCCCCHHHHCCCCCCHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
IGLLPGSKPAKLRIGVPFCLAVAERLQQHRPQSQFIIPLAPGLSYTTLSRYACASDNPLI
EEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCEE
ATYLGNSATLVQSNEELPYLCTPRGTKVWLWLPSPAYDVLMHCQICLTTLGANTAELTAL
EEEECCCEEEEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHH
MVPMMVILPTQHLAGAPIGEGLLGVLARLSFVGAAMNRFILPQGFKAWPNIWADQEIVPE
HHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
WVGPLSSELVAHYLQALLASPSRLQAIKAALREVRGEVGAVARFAQLVSETLIKERGAEA
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVIRDAP
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA