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The map label for this gene is yezE [H]

Identifier: 158336270

GI number: 158336270

Start: 3161765

End: 3162355

Strand: Reverse

Name: yezE [H]

Synonym: AM1_3132

Alternate gene names: 158336270

Gene position: 3162355-3161765 (Counterclockwise)

Preceding gene: 158336272

Following gene: 158336269

Centisome position: 48.62

GC content: 49.58

Gene sequence:

>591_bases
ATGACACGGGGTCCCGATAAGCAATTCGATACTGAAGTCGCCCTTAGTAAGGCGATGGAAGTATTTTGGGCGCACGGTTA
TGAAGCCGCTAGCCTCTCAGAATTGCTGAAAAATATGGGGATTGGTAAGAAAAGTCTGTATGACACCTTTGGCAATAAGC
AATCGCTCTTTCTAAAGGCACTTGATTACTACGCTCGAACCACCCTAAGGGATATACGCGATCGCCTGAATGCAGAAGGG
TCACCTCTGGGCAACCTCAAGCACTTACTGAAAGACTGGCAGATCATGCACAGTCAATCGGGGAGTTGTGGCTGTATGCT
CGGCACGAATATTGCTGACTTTAATACCCACGACGAAGCGATCGCAAAAGTGATGCGGACCTATTTACGCCAACTAGAAG
ATGTGTTCACTACCGCATTAACCCATGCCCAAGACCAGGGAGAAATCAGTTCTACCGTTCATCCTCGTCACCTGGCTCAG
CTACTGCTCTGTACAACCCAGGGGATGGCCTTGCTAGGCCGCGTTATGGAAGATGACACCTTACTAGACGGAACGGTGGA
AGCGGCAATGTCCTTGCTGGAGAGCAGTTAA

Upstream 100 bases:

>100_bases
ATTAATAACATATCGAAGTTATGACTTTAAAAATAACCTTGACCAATTGGTTTAAGTTATGTTAGTTTTGATACATGGTC
AAGTCACCCATAGGTTCGCA

Downstream 100 bases:

>100_bases
TTTTTTTTGGCTCAACTTAGACCAATCGTTCAAAGTTTAATCTTACCTACAGGAGACAATCCCATGACGTTCGATATTGC
TAACAAAACCATTTTGGTTA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTRGPDKQFDTEVALSKAMEVFWAHGYEAASLSELLKNMGIGKKSLYDTFGNKQSLFLKALDYYARTTLRDIRDRLNAEG
SPLGNLKHLLKDWQIMHSQSGSCGCMLGTNIADFNTHDEAIAKVMRTYLRQLEDVFTTALTHAQDQGEISSTVHPRHLAQ
LLLCTTQGMALLGRVMEDDTLLDGTVEAAMSLLESS

Sequences:

>Translated_196_residues
MTRGPDKQFDTEVALSKAMEVFWAHGYEAASLSELLKNMGIGKKSLYDTFGNKQSLFLKALDYYARTTLRDIRDRLNAEG
SPLGNLKHLLKDWQIMHSQSGSCGCMLGTNIADFNTHDEAIAKVMRTYLRQLEDVFTTALTHAQDQGEISSTVHPRHLAQ
LLLCTTQGMALLGRVMEDDTLLDGTVEAAMSLLESS
>Mature_195_residues
TRGPDKQFDTEVALSKAMEVFWAHGYEAASLSELLKNMGIGKKSLYDTFGNKQSLFLKALDYYARTTLRDIRDRLNAEGS
PLGNLKHLLKDWQIMHSQSGSCGCMLGTNIADFNTHDEAIAKVMRTYLRQLEDVFTTALTHAQDQGEISSTVHPRHLAQL
LLCTTQGMALLGRVMEDDTLLDGTVEAAMSLLESS

Specific function: Unknown

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081833, Length=178, Percent_Identity=31.4606741573034, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI87082397, Length=132, Percent_Identity=32.5757575757576, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21773; Mature: 21642

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGPDKQFDTEVALSKAMEVFWAHGYEAASLSELLKNMGIGKKSLYDTFGNKQSLFLKA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LDYYARTTLRDIRDRLNAEGSPLGNLKHLLKDWQIMHSQSGSCGCMLGTNIADFNTHDEA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
IAKVMRTYLRQLEDVFTTALTHAQDQGEISSTVHPRHLAQLLLCTTQGMALLGRVMEDDT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
LLDGTVEAAMSLLESS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRGPDKQFDTEVALSKAMEVFWAHGYEAASLSELLKNMGIGKKSLYDTFGNKQSLFLKA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LDYYARTTLRDIRDRLNAEGSPLGNLKHLLKDWQIMHSQSGSCGCMLGTNIADFNTHDEA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
IAKVMRTYLRQLEDVFTTALTHAQDQGEISSTVHPRHLAQLLLCTTQGMALLGRVMEDDT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
LLDGTVEAAMSLLESS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]