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The map label for this gene is yfdH [C]

Identifier: 158336237

GI number: 158336237

Start: 3129860

End: 3130894

Strand: Reverse

Name: yfdH [C]

Synonym: AM1_3099

Alternate gene names: 158336237

Gene position: 3130894-3129860 (Counterclockwise)

Preceding gene: 158336239

Following gene: 158336236

Centisome position: 48.14

GC content: 49.28

Gene sequence:

>1035_bases
TTGACATCATTCAGTTCCCCTTCATCAATTGCAAGCAATTCAGATCAAACAGGTAATGTAACGTATTCTTTCGTTATTCC
GATTTACAACGAAGAAGAGAATATTGCTGAACTGTATCAACGCCTGCAGGCCTTGATCAAAACCCTGGATGGTTCTGCAG
AGCTGATTTTGGTGGATGATGGTAGTTGCGATCGCACCCTCCCTCTCATTCGCCAACTGCACCAAGATGACCCTACTGTT
CGATACGTCAGCCTAGCCCGTAACTTTGGCCACCAAATTGCCTTAACCGCCGGTCTCCAGTTTGCCACCGGCCAAGCCAT
TATCGTCATGGATGCCGACCTACAAGATCCACCCGAAGTCGTCCCTGATCTGATTCAGCAATGGCAGCAGGGATACCAGG
TCGTTTACGCTCAAAGAATTTCGCGACAGCGAGAAGGCATCATTAAACGCTTGACCGCCTATCTGTTTTACCGATTTCTC
CAGCAACTCTCTGATATTCACATTCCCACGGACACCGGTGACTTTTGCCTGATGGATCGGCAAGTGGTAGATTTGCTGAA
CCAAATGCCCGAGCGCAACCGCTATATCCGGGGTCTCCGGGCTTGGGTGGGCTTTCGACAAACGGCCATTACCCTTCATC
GTCCCCCTCGATTTGCGGGAGACGTCAAATATACCTTTCACAAATCCCTGACCTTAGCTCTCAGCAGCATTATGGCCTTC
TCCAAAGTCCCCTTACGCTTGGCCACGTATCTGGGGTTATTTGCGTCAGCTTTAGCGGTCTTTATGATGTTCTTGACCCT
CTACTGGCGATTTTTCAATCCTTCCAGCCAGTTAATCGGCTACACCATGATTACCATGGCGATCTTTTTCCTGGGGGCTG
TACAGCTGATTTGTCTCGGCATTTTAGGAGAATATGTGGGCCAAATTTACGAAGAAATTAAAGGCCGTCCCCTCTATACG
GTCAAAGAGATTGGGAACGTCCCTAGCCCACAAACCACCTATTCTCAGGCATCATCCCTGCCTCGTACCCACTAG

Upstream 100 bases:

>100_bases
CGAATGCCCGGTTCATCATCCACGATCAACACGGTTAAAGGCATAAAATGTCGCGTGCGCTTTGCAGGTATCGTCTCCTT
TGTTTAGTTATAACAATCCC

Downstream 100 bases:

>100_bases
GTTCAATCCCGTTCGTTCCAACCCTACGCACACCTCATAGCCCTTCCAGACCCCAAAAAGCCCATTTCTTGAATTTGATA
GGCTTGGACAAGAAGACCAA

Product: glycosyl transferase, group 2 family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTSFSSPSSIASNSDQTGNVTYSFVIPIYNEEENIAELYQRLQALIKTLDGSAELILVDDGSCDRTLPLIRQLHQDDPTV
RYVSLARNFGHQIALTAGLQFATGQAIIVMDADLQDPPEVVPDLIQQWQQGYQVVYAQRISRQREGIIKRLTAYLFYRFL
QQLSDIHIPTDTGDFCLMDRQVVDLLNQMPERNRYIRGLRAWVGFRQTAITLHRPPRFAGDVKYTFHKSLTLALSSIMAF
SKVPLRLATYLGLFASALAVFMMFLTLYWRFFNPSSQLIGYTMITMAIFFLGAVQLICLGILGEYVGQIYEEIKGRPLYT
VKEIGNVPSPQTTYSQASSLPRTH

Sequences:

>Translated_344_residues
MTSFSSPSSIASNSDQTGNVTYSFVIPIYNEEENIAELYQRLQALIKTLDGSAELILVDDGSCDRTLPLIRQLHQDDPTV
RYVSLARNFGHQIALTAGLQFATGQAIIVMDADLQDPPEVVPDLIQQWQQGYQVVYAQRISRQREGIIKRLTAYLFYRFL
QQLSDIHIPTDTGDFCLMDRQVVDLLNQMPERNRYIRGLRAWVGFRQTAITLHRPPRFAGDVKYTFHKSLTLALSSIMAF
SKVPLRLATYLGLFASALAVFMMFLTLYWRFFNPSSQLIGYTMITMAIFFLGAVQLICLGILGEYVGQIYEEIKGRPLYT
VKEIGNVPSPQTTYSQASSLPRTH
>Mature_343_residues
TSFSSPSSIASNSDQTGNVTYSFVIPIYNEEENIAELYQRLQALIKTLDGSAELILVDDGSCDRTLPLIRQLHQDDPTVR
YVSLARNFGHQIALTAGLQFATGQAIIVMDADLQDPPEVVPDLIQQWQQGYQVVYAQRISRQREGIIKRLTAYLFYRFLQ
QLSDIHIPTDTGDFCLMDRQVVDLLNQMPERNRYIRGLRAWVGFRQTAITLHRPPRFAGDVKYTFHKSLTLALSSIMAFS
KVPLRLATYLGLFASALAVFMMFLTLYWRFFNPSSQLIGYTMITMAIFFLGAVQLICLGILGEYVGQIYEEIKGRPLYTV
KEIGNVPSPQTTYSQASSLPRTH

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788692, Length=305, Percent_Identity=40.655737704918, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788588, Length=312, Percent_Identity=32.0512820512821, Blast_Score=161, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71999402, Length=220, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325441, Length=109, Percent_Identity=36.697247706422, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585265, Length=243, Percent_Identity=27.1604938271605, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 38988; Mature: 38857

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFSSPSSIASNSDQTGNVTYSFVIPIYNEEENIAELYQRLQALIKTLDGSAELILVDD
CCCCCCCCHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GSCDRTLPLIRQLHQDDPTVRYVSLARNFGHQIALTAGLQFATGQAIIVMDADLQDPPEV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCEEECCCEEEEEECCCCCCHHH
VPDLIQQWQQGYQVVYAQRISRQREGIIKRLTAYLFYRFLQQLSDIHIPTDTGDFCLMDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHH
QVVDLLNQMPERNRYIRGLRAWVGFRQTAITLHRPPRFAGDVKYTFHKSLTLALSSIMAF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SKVPLRLATYLGLFASALAVFMMFLTLYWRFFNPSSQLIGYTMITMAIFFLGAVQLICLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILGEYVGQIYEEIKGRPLYTVKEIGNVPSPQTTYSQASSLPRTH
HHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
TSFSSPSSIASNSDQTGNVTYSFVIPIYNEEENIAELYQRLQALIKTLDGSAELILVDD
CCCCCCCHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GSCDRTLPLIRQLHQDDPTVRYVSLARNFGHQIALTAGLQFATGQAIIVMDADLQDPPEV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCEEECCCEEEEEECCCCCCHHH
VPDLIQQWQQGYQVVYAQRISRQREGIIKRLTAYLFYRFLQQLSDIHIPTDTGDFCLMDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHH
QVVDLLNQMPERNRYIRGLRAWVGFRQTAITLHRPPRFAGDVKYTFHKSLTLALSSIMAF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SKVPLRLATYLGLFASALAVFMMFLTLYWRFFNPSSQLIGYTMITMAIFFLGAVQLICLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILGEYVGQIYEEIKGRPLYTVKEIGNVPSPQTTYSQASSLPRTH
HHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]