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The map label for this gene is trpD [H]

Identifier: 158336071

GI number: 158336071

Start: 2967260

End: 2968303

Strand: Reverse

Name: trpD [H]

Synonym: AM1_2932

Alternate gene names: 158336071

Gene position: 2968303-2967260 (Counterclockwise)

Preceding gene: 158336072

Following gene: 158336070

Centisome position: 45.64

GC content: 55.84

Gene sequence:

>1044_bases
ATGACCTTAGCACCAGATACCCTAGACGGGTCTCAACTCCTCCAACAACTCCTAGACGGTCAGTCCTTGACCCAAGCAGA
AGCCTCGCAATTGATGGAAGGCTGGCTTCAAGACGCTGTCCCTCCCGTCCTGTCGGGAGCGATCTTGGCCGCCCTGCAAG
CCAAAGGCGTGTCAGCAGATGAGCTATCAGGGATGGCCACCGTGCTCTTGCAGCAATCGGTGGAGTCAGGGGTCGCAATG
CCCAGTCCCTTGATTGACACCTGTGGAACTGGCGGCGATGGCGCTTCAACCTTTAATATCTCCACTGCCGTTGCCTTTAC
GGCAGCTGCTGCTGGGCTTCCGGTGGCTAAGCATGGCAACCGCTCTGCCTCTAGTCGGGTCGGATCCGCTGACGTGCTGG
AAGCCTTGGGCATTAATCTGGCTGCCCCACCGGAAAAAATTCAGGCTGCTGTGGCAGAAGTCGGGATTACATTTTTGTTT
GCTCCGGGCTGGCATCCGGCCATGAAAGCGGTGGTGCCCCTGCGTAAGACCCTAAAAGTACGCACCATCTTCAATCTATT
GGGGCCCTTAGTGAATCCCCTCCGACCCACGGGGCAGGTCCTAGGGGTCTACGATCCAGCACTGCTGTATCCCCTCGCCT
CGGCGCTCAAGACCCTGGGTGTGCAAAGAGCGGTCGTTTTGCATGGGCGAGAAAACTTAGATGAAGCCGGATTAGGCGAT
CTGACGGATATCGCAGTGGTTGATCAGCAACAGGTAAGCCAGGATATTTTAGAGCCTGCGGAATTAGGGTTGACTGCGGC
CCCGCTGACGGCCCTAAAAGGCGGTGGTGTGGACGAAAATGCCGCTATTTTACAAGCGGTGCTCCAAGGCAAAGGCACAT
CTGCCCAAACCGATGTTGTGGCCCTGAATACAGCATTAGCCTTATTTGTCGGTCATGCTGTAGAGACCTATGCTGAGGGA
GTGACTCAAGCCAAAGCCATTCTGGCTAGCGGTGCTGCTTGGCAGAAGTTGCAGCAGTTAGTGGCTTTTTTACAGCAGGC
TTAG

Upstream 100 bases:

>100_bases
ATCGCATTCTATGAAACACTAGGAGCAACCGTTCTCCCCGATTGGCGAACTTGTCGAGTCACGGGGGCTGCTCTCACCAC
TCTAGCCTCAGGATAGTGTT

Downstream 100 bases:

>100_bases
GCCCTCGGCACATTCTGAGGACTGTGCCAGAATGAAAGTCATGCATTGTCTTTTTAGTTTTGATTGTGATTGAGGTCGAA
GTTCATCGCCAACTCCATGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTLAPDTLDGSQLLQQLLDGQSLTQAEASQLMEGWLQDAVPPVLSGAILAALQAKGVSADELSGMATVLLQQSVESGVAM
PSPLIDTCGTGGDGASTFNISTAVAFTAAAAGLPVAKHGNRSASSRVGSADVLEALGINLAAPPEKIQAAVAEVGITFLF
APGWHPAMKAVVPLRKTLKVRTIFNLLGPLVNPLRPTGQVLGVYDPALLYPLASALKTLGVQRAVVLHGRENLDEAGLGD
LTDIAVVDQQQVSQDILEPAELGLTAAPLTALKGGGVDENAAILQAVLQGKGTSAQTDVVALNTALALFVGHAVETYAEG
VTQAKAILASGAAWQKLQQLVAFLQQA

Sequences:

>Translated_347_residues
MTLAPDTLDGSQLLQQLLDGQSLTQAEASQLMEGWLQDAVPPVLSGAILAALQAKGVSADELSGMATVLLQQSVESGVAM
PSPLIDTCGTGGDGASTFNISTAVAFTAAAAGLPVAKHGNRSASSRVGSADVLEALGINLAAPPEKIQAAVAEVGITFLF
APGWHPAMKAVVPLRKTLKVRTIFNLLGPLVNPLRPTGQVLGVYDPALLYPLASALKTLGVQRAVVLHGRENLDEAGLGD
LTDIAVVDQQQVSQDILEPAELGLTAAPLTALKGGGVDENAAILQAVLQGKGTSAQTDVVALNTALALFVGHAVETYAEG
VTQAKAILASGAAWQKLQQLVAFLQQA
>Mature_346_residues
TLAPDTLDGSQLLQQLLDGQSLTQAEASQLMEGWLQDAVPPVLSGAILAALQAKGVSADELSGMATVLLQQSVESGVAMP
SPLIDTCGTGGDGASTFNISTAVAFTAAAAGLPVAKHGNRSASSRVGSADVLEALGINLAAPPEKIQAAVAEVGITFLFA
PGWHPAMKAVVPLRKTLKVRTIFNLLGPLVNPLRPTGQVLGVYDPALLYPLASALKTLGVQRAVVLHGRENLDEAGLGDL
TDIAVVDQQQVSQDILEPAELGLTAAPLTALKGGGVDENAAILQAVLQGKGTSAQTDVVALNTALALFVGHAVETYAEGV
TQAKAILASGAAWQKLQQLVAFLQQA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:
GO:0000162: Anthranilate phosphoribosyltransferase
GO:0004048: Anthranilate phosphoribosyltransferase
GO:0008152: Anthranilate phosphoribosyltransferase
GO:0008652: Anthranilate phosphoribosyltransferase
GO:0009073: Anthranilate phosphoribosyltransferase
GO:0016740: Anthranilate phosphoribosyltransferase
GO:0016757: Anthranilate phosphoribosyltransferase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=39.9399399399399, Blast_Score=208, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6320561, Length=276, Percent_Identity=31.5217391304348, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35479; Mature: 35348

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAPDTLDGSQLLQQLLDGQSLTQAEASQLMEGWLQDAVPPVLSGAILAALQAKGVSAD
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
ELSGMATVLLQQSVESGVAMPSPLIDTCGTGGDGASTFNISTAVAFTAAAAGLPVAKHGN
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCC
RSASSRVGSADVLEALGINLAAPPEKIQAAVAEVGITFLFAPGWHPAMKAVVPLRKTLKV
CHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHH
RTIFNLLGPLVNPLRPTGQVLGVYDPALLYPLASALKTLGVQRAVVLHGRENLDEAGLGD
HHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCC
LTDIAVVDQQQVSQDILEPAELGLTAAPLTALKGGGVDENAAILQAVLQGKGTSAQTDVV
CHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHH
ALNTALALFVGHAVETYAEGVTQAKAILASGAAWQKLQQLVAFLQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLAPDTLDGSQLLQQLLDGQSLTQAEASQLMEGWLQDAVPPVLSGAILAALQAKGVSAD
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
ELSGMATVLLQQSVESGVAMPSPLIDTCGTGGDGASTFNISTAVAFTAAAAGLPVAKHGN
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCC
RSASSRVGSADVLEALGINLAAPPEKIQAAVAEVGITFLFAPGWHPAMKAVVPLRKTLKV
CHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHH
RTIFNLLGPLVNPLRPTGQVLGVYDPALLYPLASALKTLGVQRAVVLHGRENLDEAGLGD
HHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCCCC
LTDIAVVDQQQVSQDILEPAELGLTAAPLTALKGGGVDENAAILQAVLQGKGTSAQTDVV
CHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHH
ALNTALALFVGHAVETYAEGVTQAKAILASGAAWQKLQQLVAFLQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA