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The map label for this gene is cobB [H]

Identifier: 158336022

GI number: 158336022

Start: 2920236

End: 2921630

Strand: Direct

Name: cobB [H]

Synonym: AM1_2881

Alternate gene names: 158336022

Gene position: 2920236-2921630 (Clockwise)

Preceding gene: 158336019

Following gene: 158336026

Centisome position: 44.9

GC content: 50.39

Gene sequence:

>1395_bases
ATGTCACTAGTGATTGCAGCCGATCGCAGTGGTGTGGGCAAAACCACTGTGACCGCTGCCATCCTAGCGAGCTTGAAAGC
TCGACCGGGTGTCGTGCAATCCTTCAAAGTTGGACCAGACTATATTGATCCAATGTTTCACACGGTAGTCACCCAGCGAC
CTTGCCGAAATTTAGATCCCATTCTCACATCTGAACCCTATACCCAGCAAATCTTTCACACCCATACTCAGCAGGCCAAC
TATGCCCTAATTGAAGGGGTCATGGGCTTATTTGATGGCGCTATTGGGCAGCAAGGGAGAGGCAGCACCGCTCATATCGC
CCGGCTCTTAGATGTACCCATCGCTCTCGTTCTAGACTGTAGTCGTTTATCAGACTCTATCGCGGCTTTGGTCCATGGCT
ACCGATCTTTTGATCCACAACTCCAGATTGCCGGAGTGATCCTCAATCGGGTAGGAAGCGATCGCCATCTGCAAAGTTTA
AAGTCAGCATTACAGCCGCTCTCCATTCGAATATTAGGTGTCTTGCAGCGACAGCCGTCCATCCATATTCCCGATCGTCA
CTTAGGTTTAGTCCCTATCGACGAATTAGAGGGGGCTGACGGGCTGTTACAGCAGTTGGCCACAGTCGGAAATCGTTGTT
TTGATTGGTCAGCTTTATTGCCTTTATTAGCTACAACCCAAGCCACTCCAACGCCACTGGCAGCTCCTGTTCGGCCTCAA
ATCAGTGCTTTAACCTCTTCTACACCGTCTAGCCGTGTCCGTATTGCGATCGCAAAAGACGTCGCCTTTAGTTTTTACTA
TGCCGACAATCTCGATCAGCTCCGACACCTCGGTGCAGAACTGGTATTTTGGAGCCCAATCCATGACAACGCCTTACCCA
ACCATATCCACGGTCTCTATCTCGGTGGTGGCTTTCCTGAAATGTTTGCCGTTGAATTATCTGAGAATGTCGCCGTTCTG
CAGGATCTTAAAACCGCGATTCAAGCTGGGTTACCCACCTATGCTGAATGTGGCGGGCTGATGTATTTGTGTGAATCCTT
GCAAGGTTTGCAAGGAAAAAGGTTTCCGATGGTGGGCGTACTGCCAGCAAACGTCAAGATGGCGAAGCGCTTAACGCTGG
GGTATCGATGTGCGATCTCAACCCAAAACACTCCCCTACTCACGGCAGGAACGACGGTTTGGGGTCATGAATTTCACCAC
TCCGAACTGGATCAGGACGGAGATAACCCCACGTATACGTTCTCACGACAGACCGTTGCTCACCCCTCAGAGATTTCAGA
AGGCTGGCATCGCTATAATCTTCACGCCTCGTACCTACATCTCCACTGGGGAAACCAGCCTGAGATACCAAAACGTTTTA
TCCAGCAATGCCGAGACTTTAAAGCAACCTGCTGA

Upstream 100 bases:

>100_bases
GATGAGTAGTGTTGAGAGAGTTCACTTTCAGAGCATAGATGTTGTACGCTGGCACAGCATCTTTGCAGATTTAGCGTAAC
CATTTTGAAGAGGACCCTGA

Downstream 100 bases:

>100_bases
AGCTCTAGCAGGCTTTTGGTCTCGCCAATGCATTCTTAGACATGGCACAACGTCGCAACCGAGGCAAACATTCTTGTTGA
TAAAAACCGCTGATCACCGG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSLVIAADRSGVGKTTVTAAILASLKARPGVVQSFKVGPDYIDPMFHTVVTQRPCRNLDPILTSEPYTQQIFHTHTQQAN
YALIEGVMGLFDGAIGQQGRGSTAHIARLLDVPIALVLDCSRLSDSIAALVHGYRSFDPQLQIAGVILNRVGSDRHLQSL
KSALQPLSIRILGVLQRQPSIHIPDRHLGLVPIDELEGADGLLQQLATVGNRCFDWSALLPLLATTQATPTPLAAPVRPQ
ISALTSSTPSSRVRIAIAKDVAFSFYYADNLDQLRHLGAELVFWSPIHDNALPNHIHGLYLGGGFPEMFAVELSENVAVL
QDLKTAIQAGLPTYAECGGLMYLCESLQGLQGKRFPMVGVLPANVKMAKRLTLGYRCAISTQNTPLLTAGTTVWGHEFHH
SELDQDGDNPTYTFSRQTVAHPSEISEGWHRYNLHASYLHLHWGNQPEIPKRFIQQCRDFKATC

Sequences:

>Translated_464_residues
MSLVIAADRSGVGKTTVTAAILASLKARPGVVQSFKVGPDYIDPMFHTVVTQRPCRNLDPILTSEPYTQQIFHTHTQQAN
YALIEGVMGLFDGAIGQQGRGSTAHIARLLDVPIALVLDCSRLSDSIAALVHGYRSFDPQLQIAGVILNRVGSDRHLQSL
KSALQPLSIRILGVLQRQPSIHIPDRHLGLVPIDELEGADGLLQQLATVGNRCFDWSALLPLLATTQATPTPLAAPVRPQ
ISALTSSTPSSRVRIAIAKDVAFSFYYADNLDQLRHLGAELVFWSPIHDNALPNHIHGLYLGGGFPEMFAVELSENVAVL
QDLKTAIQAGLPTYAECGGLMYLCESLQGLQGKRFPMVGVLPANVKMAKRLTLGYRCAISTQNTPLLTAGTTVWGHEFHH
SELDQDGDNPTYTFSRQTVAHPSEISEGWHRYNLHASYLHLHWGNQPEIPKRFIQQCRDFKATC
>Mature_463_residues
SLVIAADRSGVGKTTVTAAILASLKARPGVVQSFKVGPDYIDPMFHTVVTQRPCRNLDPILTSEPYTQQIFHTHTQQANY
ALIEGVMGLFDGAIGQQGRGSTAHIARLLDVPIALVLDCSRLSDSIAALVHGYRSFDPQLQIAGVILNRVGSDRHLQSLK
SALQPLSIRILGVLQRQPSIHIPDRHLGLVPIDELEGADGLLQQLATVGNRCFDWSALLPLLATTQATPTPLAAPVRPQI
SALTSSTPSSRVRIAIAKDVAFSFYYADNLDQLRHLGAELVFWSPIHDNALPNHIHGLYLGGGFPEMFAVELSENVAVLQ
DLKTAIQAGLPTYAECGGLMYLCESLQGLQGKRFPMVGVLPANVKMAKRLTLGYRCAISTQNTPLLTAGTTVWGHEFHHS
ELDQDGDNPTYTFSRQTVAHPSEISEGWHRYNLHASYLHLHWGNQPEIPKRFIQQCRDFKATC

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50820; Mature: 50689

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVIAADRSGVGKTTVTAAILASLKARPGVVQSFKVGPDYIDPMFHTVVTQRPCRNLDP
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHHHHHHCCCCCCCCC
ILTSEPYTQQIFHTHTQQANYALIEGVMGLFDGAIGQQGRGSTAHIARLLDVPIALVLDC
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHH
SRLSDSIAALVHGYRSFDPQLQIAGVILNRVGSDRHLQSLKSALQPLSIRILGVLQRQPS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
IHIPDRHLGLVPIDELEGADGLLQQLATVGNRCFDWSALLPLLATTQATPTPLAAPVRPQ
CCCCCCCCCCEEHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
ISALTSSTPSSRVRIAIAKDVAFSFYYADNLDQLRHLGAELVFWSPIHDNALPNHIHGLY
HHHHHCCCCCCEEEEEEEECCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCCCCEEE
LGGGFPEMFAVELSENVAVLQDLKTAIQAGLPTYAECGGLMYLCESLQGLQGKRFPMVGV
ECCCCHHHEEEECCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHCCCCCCCCCEEEE
LPANVKMAKRLTLGYRCAISTQNTPLLTAGTTVWGHEFHHSELDQDGDNPTYTFSRQTVA
ECCCHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCC
HPSEISEGWHRYNLHASYLHLHWGNQPEIPKRFIQQCRDFKATC
CHHHHHCCHHEEECEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLVIAADRSGVGKTTVTAAILASLKARPGVVQSFKVGPDYIDPMFHTVVTQRPCRNLDP
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHHHHHHCCCCCCCCC
ILTSEPYTQQIFHTHTQQANYALIEGVMGLFDGAIGQQGRGSTAHIARLLDVPIALVLDC
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHH
SRLSDSIAALVHGYRSFDPQLQIAGVILNRVGSDRHLQSLKSALQPLSIRILGVLQRQPS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
IHIPDRHLGLVPIDELEGADGLLQQLATVGNRCFDWSALLPLLATTQATPTPLAAPVRPQ
CCCCCCCCCCEEHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
ISALTSSTPSSRVRIAIAKDVAFSFYYADNLDQLRHLGAELVFWSPIHDNALPNHIHGLY
HHHHHCCCCCCEEEEEEEECCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCCCCEEE
LGGGFPEMFAVELSENVAVLQDLKTAIQAGLPTYAECGGLMYLCESLQGLQGKRFPMVGV
ECCCCHHHEEEECCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHCCCCCCCCCEEEE
LPANVKMAKRLTLGYRCAISTQNTPLLTAGTTVWGHEFHHSELDQDGDNPTYTFSRQTVA
ECCCHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCC
HPSEISEGWHRYNLHASYLHLHWGNQPEIPKRFIQQCRDFKATC
CHHHHHCCHHEEECEEEEEEEECCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA