Click here to switch to the map view.

The map label for this gene is nusG [H]

Identifier: 158336005

GI number: 158336005

Start: 2904669

End: 2905289

Strand: Direct

Name: nusG [H]

Synonym: AM1_2864

Alternate gene names: 158336005

Gene position: 2904669-2905289 (Clockwise)

Preceding gene: 158336004

Following gene: 158336006

Centisome position: 44.66

GC content: 48.15

Gene sequence:

>621_bases
ATGACTGATGACCCCCTAAGTACCACTCCGGCTGTTAGTTCAGTCCCCGAAGGTCCCCTTGAAATTCGGCATTGGTATGC
CGTTCAAGTTGCTTCTGGATGCGAGAAAAAGGTCAAGCATAACCTGGAACAACGCCTGCAAACCCTAGATGTTGCAGACC
GTATTGTTCAGATTGAAATTCCACAAACCCCGACTATTAAGGTTCGGAAAGATGGTAGCCGTCTAACAGGCGAAGAAAAA
GTCTTTCCCGGCTATGTACTAGTCCGCATGATTTTAGATGACGAAACCTGGCAGGTGGTCAAAAACACCCCCAACGTCAT
CAACTTTGTCGGTGCCGAACAGCAACGTCGGTACGGTCGTGGTCGCGGTCATGTTAAACCGATGCCCCTCAGTCCTTCAG
AAGTCGAGCGGATCTTCCGCCAGGCTCAAGAGCAAGAGCCTGTGGTCAAAGTCGATATGTCTGTTGGCGATAAGATTCAA
GTTCTCAATGGTCCATTCAAAGACTTTGAGGGTGAAGTAATTGAAGTTAGCCTTGAGCGTAACAAGCTCAAAGCGCTACT
TTCGATTTTTGGGCGGGATACCCCCGTAGAATTGGAATTTAATCAGGTGCGAAAAGAGTAA

Upstream 100 bases:

>100_bases
GATTGCAGTCTTTTTGATGGTTTCACTCTCTGCCTTCATTTTTTCATTTATCGATAACTTGTTTAGGTGGGTTTCCACAC
TCGTATTTGGATAAGTGCCC

Downstream 100 bases:

>100_bases
TTCATCCATGGCAAAAAAAGTAGTAGCAATTATTAAATTGGCAATCGCAGCTGGCAAAGCCAACCCTGCCCCCCCAATTG
GACCCGCCTTAGGACAACAT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTDDPLSTTPAVSSVPEGPLEIRHWYAVQVASGCEKKVKHNLEQRLQTLDVADRIVQIEIPQTPTIKVRKDGSRLTGEEK
VFPGYVLVRMILDDETWQVVKNTPNVINFVGAEQQRRYGRGRGHVKPMPLSPSEVERIFRQAQEQEPVVKVDMSVGDKIQ
VLNGPFKDFEGEVIEVSLERNKLKALLSIFGRDTPVELEFNQVRKE

Sequences:

>Translated_206_residues
MTDDPLSTTPAVSSVPEGPLEIRHWYAVQVASGCEKKVKHNLEQRLQTLDVADRIVQIEIPQTPTIKVRKDGSRLTGEEK
VFPGYVLVRMILDDETWQVVKNTPNVINFVGAEQQRRYGRGRGHVKPMPLSPSEVERIFRQAQEQEPVVKVDMSVGDKIQ
VLNGPFKDFEGEVIEVSLERNKLKALLSIFGRDTPVELEFNQVRKE
>Mature_205_residues
TDDPLSTTPAVSSVPEGPLEIRHWYAVQVASGCEKKVKHNLEQRLQTLDVADRIVQIEIPQTPTIKVRKDGSRLTGEEKV
FPGYVLVRMILDDETWQVVKNTPNVINFVGAEQQRRYGRGRGHVKPMPLSPSEVERIFRQAQEQEPVVKVDMSVGDKIQV
LNGPFKDFEGEVIEVSLERNKLKALLSIFGRDTPVELEFNQVRKE

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:
GO:0006351: Transcription antitermination protein nusG
GO:0006353: Transcription antitermination protein nusG
GO:0006355: Transcription antitermination protein nusG
GO:0031564: Transcription antitermination protein nusG
GO:0032784: Transcription antitermination protein nusG
GO:0032968: Transcription antitermination protein nusG

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=185, Percent_Identity=37.2972972972973, Blast_Score=130, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 23400; Mature: 23269

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDPLSTTPAVSSVPEGPLEIRHWYAVQVASGCEKKVKHNLEQRLQTLDVADRIVQIEI
CCCCCCCCCCCCCCCCCCCCEEHEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHEEEEEEC
PQTPTIKVRKDGSRLTGEEKVFPGYVLVRMILDDETWQVVKNTPNVINFVGAEQQRRYGR
CCCCEEEEECCCCCCCCCCCCCCHHHEEHHHHCCCHHHHHHCCCCEEEECCCHHHHHHCC
GRGHVKPMPLSPSEVERIFRQAQEQEPVVKVDMSVGDKIQVLNGPFKDFEGEVIEVSLER
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCEEEEEECH
NKLKALLSIFGRDTPVELEFNQVRKE
HHHHHHHHHHCCCCCEEEEHHHHCCC
>Mature Secondary Structure 
TDDPLSTTPAVSSVPEGPLEIRHWYAVQVASGCEKKVKHNLEQRLQTLDVADRIVQIEI
CCCCCCCCCCCCCCCCCCCEEHEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHEEEEEEC
PQTPTIKVRKDGSRLTGEEKVFPGYVLVRMILDDETWQVVKNTPNVINFVGAEQQRRYGR
CCCCEEEEECCCCCCCCCCCCCCHHHEEHHHHCCCHHHHHHCCCCEEEECCCHHHHHHCC
GRGHVKPMPLSPSEVERIFRQAQEQEPVVKVDMSVGDKIQVLNGPFKDFEGEVIEVSLER
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCEEEEEECH
NKLKALLSIFGRDTPVELEFNQVRKE
HHHHHHHHHHCCCCCEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685084; 8905231; 7505271 [H]