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The map label for this gene is anmK

Identifier: 158335982

GI number: 158335982

Start: 2881729

End: 2882868

Strand: Reverse

Name: anmK

Synonym: AM1_2840

Alternate gene names: 158335982

Gene position: 2882868-2881729 (Counterclockwise)

Preceding gene: 158335983

Following gene: 158335981

Centisome position: 44.33

GC content: 53.68

Gene sequence:

>1140_bases
ATGCATGTGATTGGCTTGATGAGCGGCACCTCCGTGGATGGGATTGATGCCGCCCTCGTAGAGATTTCTGGCCGAGAACT
GGATTTACAGGTTGATCTGATTGCCGCTCAGACCTATCCCTATCCCGATGCCCTCCGAAATCAAATTCTCGCGGTCTGTC
GGGGAGAGCCCCTCAGTATTGAGGCATTGGCAGGATTGGATGATGCGATTGCCATGCAATTTGCCCAAGCGGCCCAGTCG
ATTCAGGCTGAGGCCACGCTGACTGCTGAACTGATTGGCTCCCACGGTCAAACGGTGTTTCATCGTCCTCCCCAGGGAAA
CCTAGGCTATACCCTCCAAATCGGACGTGGTGCTGTGATTGCCCACCAAACAGGCATCAACACTGTCAGCAATTTCCGGG
TTGCCGATATGGCAGCCGGGGGTCAGGGCGCTCCCTTGGTCTCCAAACTCGATATCTGTTTACTCAGCCATCCTGAGTTC
TACCGCTGTGTGCAAAATATTGGCGGGATTGGCAATGTTACCTACCTGCCGCCGTTAACCGATGCCAGCCAACTGGGGAT
GGGCGTTAAAGGTTGGGACACTGGCCCAGGCAATGTCTTAATGGATTTGGCCGTGGCGCACTTTTCTAAGGGCGAACTCA
CCTACGATGCCGACGGAGCCTGGGCGGCTCAGGGAAATCCTTGTCAGCCTTTAATCGAGGAATGGCTGAGGCATCCTTTC
TTTCAAGCGCCACCCCCTAAGTCCACAGGACGAGAATTATTTAGTCCCGATTATTTACAGACTTGTTTGCAAACGGCAGC
GTCTTATCAGCTCAGTCCGGCGGATATGCTGGCGACGCTGACGGATTTTACCGCAGCCACCATTGTCTATAACTATGACC
AGTTTTTACCACATCCTCCTGATCAAGTGGTTCTCTGTGGAGGTGGGAGTCGCAATGGTTATTTACGGCAGTGTTTGCAG
CAGCGCTTAGGCGGTAGCACTGTGTTAACGACGGATGATGTGGGGTTGAATTCTGATGCGAAGGAAGCGATCGCATTTGC
CGTATTGGCCTATTGGCAACAGCTGCAAATCCCTGGCAACGTACCGGCGGTGACCGGAGCATCAGGCCCGATTCTCCTGG
GAGAATTGCACCTTGTCTGA

Upstream 100 bases:

>100_bases
CTGATCTAAAGAAAGCGGCTGATCTGTATGCCAAGCAGGGTCGCACCGATGACTACAACAACGTACTTAGTGTTTTACGT
TCTTTGGGAGAAGGATAACC

Downstream 100 bases:

>100_bases
TCCAGAGGCTTGGCCCAGTGGGCATCCTAAGGAAAGAACAAGGACTCACCAACATTAACAAAATGCCAGAGAATAGGGGC
ACTGCGACCCACACATTTTT

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MHVIGLMSGTSVDGIDAALVEISGRELDLQVDLIAAQTYPYPDALRNQILAVCRGEPLSIEALAGLDDAIAMQFAQAAQS
IQAEATLTAELIGSHGQTVFHRPPQGNLGYTLQIGRGAVIAHQTGINTVSNFRVADMAAGGQGAPLVSKLDICLLSHPEF
YRCVQNIGGIGNVTYLPPLTDASQLGMGVKGWDTGPGNVLMDLAVAHFSKGELTYDADGAWAAQGNPCQPLIEEWLRHPF
FQAPPPKSTGRELFSPDYLQTCLQTAASYQLSPADMLATLTDFTAATIVYNYDQFLPHPPDQVVLCGGGSRNGYLRQCLQ
QRLGGSTVLTTDDVGLNSDAKEAIAFAVLAYWQQLQIPGNVPAVTGASGPILLGELHLV

Sequences:

>Translated_379_residues
MHVIGLMSGTSVDGIDAALVEISGRELDLQVDLIAAQTYPYPDALRNQILAVCRGEPLSIEALAGLDDAIAMQFAQAAQS
IQAEATLTAELIGSHGQTVFHRPPQGNLGYTLQIGRGAVIAHQTGINTVSNFRVADMAAGGQGAPLVSKLDICLLSHPEF
YRCVQNIGGIGNVTYLPPLTDASQLGMGVKGWDTGPGNVLMDLAVAHFSKGELTYDADGAWAAQGNPCQPLIEEWLRHPF
FQAPPPKSTGRELFSPDYLQTCLQTAASYQLSPADMLATLTDFTAATIVYNYDQFLPHPPDQVVLCGGGSRNGYLRQCLQ
QRLGGSTVLTTDDVGLNSDAKEAIAFAVLAYWQQLQIPGNVPAVTGASGPILLGELHLV
>Mature_379_residues
MHVIGLMSGTSVDGIDAALVEISGRELDLQVDLIAAQTYPYPDALRNQILAVCRGEPLSIEALAGLDDAIAMQFAQAAQS
IQAEATLTAELIGSHGQTVFHRPPQGNLGYTLQIGRGAVIAHQTGINTVSNFRVADMAAGGQGAPLVSKLDICLLSHPEF
YRCVQNIGGIGNVTYLPPLTDASQLGMGVKGWDTGPGNVLMDLAVAHFSKGELTYDADGAWAAQGNPCQPLIEEWLRHPF
FQAPPPKSTGRELFSPDYLQTCLQTAASYQLSPADMLATLTDFTAATIVYNYDQFLPHPPDQVVLCGGGSRNGYLRQCLQ
QRLGGSTVLTTDDVGLNSDAKEAIAFAVLAYWQQLQIPGNVPAVTGASGPILLGELHLV

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:
GO:0000166: Anhydro-N-acetylmuramic acid kinase
GO:0005524: Anhydro-N-acetylmuramic acid kinase
GO:0005975: Anhydro-N-acetylmuramic acid kinase
GO:0006040: Anhydro-N-acetylmuramic acid kinase
GO:0009254: Anhydro-N-acetylmuramic acid kinase
GO:0016301: Anhydro-N-acetylmuramic acid kinase
GO:0016310: Anhydro-N-acetylmuramic acid kinase
GO:0016740: Anhydro-N-acetylmuramic acid kinase
GO:0016773: Anhydro-N-acetylmuramic acid kinase

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=376, Percent_Identity=41.2234042553192, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_ACAM1 (B0CAA5)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517156.1
- ProteinModelPortal:   B0CAA5
- SMR:   B0CAA5
- GeneID:   5681648
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_2840
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   AMAR329726:AM1_2840-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 40224; Mature: 40224

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVIGLMSGTSVDGIDAALVEISGRELDLQVDLIAAQTYPYPDALRNQILAVCRGEPLSI
CEEEEECCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
EALAGLDDAIAMQFAQAAQSIQAEATLTAELIGSHGQTVFHRPPQGNLGYTLQIGRGAVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCEEE
AHQTGINTVSNFRVADMAAGGQGAPLVSKLDICLLSHPEFYRCVQNIGGIGNVTYLPPLT
EEECCCCCHHCCEEEEECCCCCCCCHHHHHHEEEECCCHHHHHHHHCCCCCCEEECCCCC
DASQLGMGVKGWDTGPGNVLMDLAVAHFSKGELTYDADGAWAAQGNPCQPLIEEWLRHPF
CHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
FQAPPPKSTGRELFSPDYLQTCLQTAASYQLSPADMLATLTDFTAATIVYNYDQFLPHPP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECHHHCCCCC
DQVVLCGGGSRNGYLRQCLQQRLGGSTVLTTDDVGLNSDAKEAIAFAVLAYWQQLQIPGN
CCEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VPAVTGASGPILLGELHLV
CCEECCCCCCEEEEEEECC
>Mature Secondary Structure
MHVIGLMSGTSVDGIDAALVEISGRELDLQVDLIAAQTYPYPDALRNQILAVCRGEPLSI
CEEEEECCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
EALAGLDDAIAMQFAQAAQSIQAEATLTAELIGSHGQTVFHRPPQGNLGYTLQIGRGAVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCEEE
AHQTGINTVSNFRVADMAAGGQGAPLVSKLDICLLSHPEFYRCVQNIGGIGNVTYLPPLT
EEECCCCCHHCCEEEEECCCCCCCCHHHHHHEEEECCCHHHHHHHHCCCCCCEEECCCCC
DASQLGMGVKGWDTGPGNVLMDLAVAHFSKGELTYDADGAWAAQGNPCQPLIEEWLRHPF
CHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
FQAPPPKSTGRELFSPDYLQTCLQTAASYQLSPADMLATLTDFTAATIVYNYDQFLPHPP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECHHHCCCCC
DQVVLCGGGSRNGYLRQCLQQRLGGSTVLTTDDVGLNSDAKEAIAFAVLAYWQQLQIPGN
CCEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VPAVTGASGPILLGELHLV
CCEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA