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The map label for this gene is resE [H]

Identifier: 158335942

GI number: 158335942

Start: 2830717

End: 2832129

Strand: Reverse

Name: resE [H]

Synonym: AM1_2800

Alternate gene names: 158335942

Gene position: 2832129-2830717 (Counterclockwise)

Preceding gene: 158335943

Following gene: 158335941

Centisome position: 43.55

GC content: 50.67

Gene sequence:

>1413_bases
ATGTTCCAAACAACTCGACGGCGATTAGCACTCTGGTATACAGGGGTCACTGCGATTTTGCTGCTGGTTTTTGCTAGCGG
CTTTTATCTGTATGTACGGGGAACTTTGATTGAGCGGGTCGATGATACGTTGAGCCATGTGGTGGAGGTGGTACAGCGTT
CGCTAGTCGTCGAAGCGAGTAATGCTGATCTTTCCCCTCTAGACTCTCCGTTTATTGTCAATTTAGAAGCGAGCTTTGGT
GATCCACCGGATGCGGTGGATGATGACCGAATTGACTTGGAATGGTTTAGTGCGGAGGGTGATTTGCTATGGTCAACTCT
ATCTGAAGTATTAGAGGTTCCCATTCGTTTGGGCTACCGTGGCGAAACGGTTGAAATCGCAGACGATTACTTGTTGCGGC
AGCTCACTCAGCGGGTCATGTTGAATGGTAATGTGCTGGGCTATCTGCGGGTGAGCCATCCCTGGTTTGAGGTGACAAAA
CCTGCTCGTCAATTGTTTATTGACCTGAGCTTAGGGACGAGTTTGTTAGTCGGGTTAGTGGCGATGACAGGTTGGTTCCT
CTCAGGGTTAGCGATTGAACCCATTCAAGACTCTTACCAGCATCTGAAGCAGTTTACGGCGGATGCCTCCCATGAGTTGC
GAAATCCGATCGCACTGATCCAAACAAATGTGCAAGTAGCGTTAGCGGATCCCGAACTGGAGATGCCTGAGCAACGGCAG
CAGCTGGAAGTGATTGAGCGGCTGACTCAGCGTCTGGGACGCTTGGTGGATGACTTATTGTTTTTAGCCCGCCAAGACAG
TGGCATGCTCGAGATTGACTATCAACCTTGTCCGTTGGATGCTGTGTTGATGGAAGTGGTGGAAGACCAAAGAGCCTTAG
CAACGAGTAAGGGGGTTCATCTACATTTGCATTTAGAAGAGACAGGGGCAGAAACGGTCCCTAGTGAAGAGCCCTTTTCG
GTGATTGGAGATTACGATCAGCTGGTCCGGTTGTTTACCAATTTGGTGAGTAATGGCATTCAATACACCCCTGCAGAGGG
CAGAGTTAGGGTGACGCTCAAACAGTCTCTTCGACAAGGCATACCTTACCTAAAAGCGATGGTTGAAGATGAGGGGCTAG
GCATCCCGGCGGAGGCAATTCCCCATGTGTTTGATCGGTTTTACCGAGCGGATCCGGCTCGACAGCGGTCGTTAATACCG
GCGACTCAGCAACCTGTTTCTTCTGGCAAAGTGATGGGGACGGGATTGGGGCTTGCGATCGCACAAGCGATTTGCCACAA
TCACCAAGGCCAAATGAGTGTTAGCAGTAGATTGCAGCAGGGGACTCTCTTCACAGTGACCCTACCCCAGCAGCTCTCCA
GAAAGATTGACGTTAAATCCGCGCCCTCGGAAGAGATAAATCAGCTACCCTGA

Upstream 100 bases:

>100_bases
GTGATTGCGATGGTGGTGACAATTCAGCTTTATGCCAAGAAGCGGAAGCGAGATAAGGAAAGGCTGGCTTTAGAAACGGC
ATCAGAATAGTCTTGACGGC

Downstream 100 bases:

>100_bases
GAAAGGCAAGATTACCAAAAAGGCTTAAGCATGAAGGATTGGAATCCAGCAAATCTCGGAATTATCATTGCGTTGTTGGT
TCTGTTGGGCCTCAGTTCTG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MFQTTRRRLALWYTGVTAILLLVFASGFYLYVRGTLIERVDDTLSHVVEVVQRSLVVEASNADLSPLDSPFIVNLEASFG
DPPDAVDDDRIDLEWFSAEGDLLWSTLSEVLEVPIRLGYRGETVEIADDYLLRQLTQRVMLNGNVLGYLRVSHPWFEVTK
PARQLFIDLSLGTSLLVGLVAMTGWFLSGLAIEPIQDSYQHLKQFTADASHELRNPIALIQTNVQVALADPELEMPEQRQ
QLEVIERLTQRLGRLVDDLLFLARQDSGMLEIDYQPCPLDAVLMEVVEDQRALATSKGVHLHLHLEETGAETVPSEEPFS
VIGDYDQLVRLFTNLVSNGIQYTPAEGRVRVTLKQSLRQGIPYLKAMVEDEGLGIPAEAIPHVFDRFYRADPARQRSLIP
ATQQPVSSGKVMGTGLGLAIAQAICHNHQGQMSVSSRLQQGTLFTVTLPQQLSRKIDVKSAPSEEINQLP

Sequences:

>Translated_470_residues
MFQTTRRRLALWYTGVTAILLLVFASGFYLYVRGTLIERVDDTLSHVVEVVQRSLVVEASNADLSPLDSPFIVNLEASFG
DPPDAVDDDRIDLEWFSAEGDLLWSTLSEVLEVPIRLGYRGETVEIADDYLLRQLTQRVMLNGNVLGYLRVSHPWFEVTK
PARQLFIDLSLGTSLLVGLVAMTGWFLSGLAIEPIQDSYQHLKQFTADASHELRNPIALIQTNVQVALADPELEMPEQRQ
QLEVIERLTQRLGRLVDDLLFLARQDSGMLEIDYQPCPLDAVLMEVVEDQRALATSKGVHLHLHLEETGAETVPSEEPFS
VIGDYDQLVRLFTNLVSNGIQYTPAEGRVRVTLKQSLRQGIPYLKAMVEDEGLGIPAEAIPHVFDRFYRADPARQRSLIP
ATQQPVSSGKVMGTGLGLAIAQAICHNHQGQMSVSSRLQQGTLFTVTLPQQLSRKIDVKSAPSEEINQLP
>Mature_470_residues
MFQTTRRRLALWYTGVTAILLLVFASGFYLYVRGTLIERVDDTLSHVVEVVQRSLVVEASNADLSPLDSPFIVNLEASFG
DPPDAVDDDRIDLEWFSAEGDLLWSTLSEVLEVPIRLGYRGETVEIADDYLLRQLTQRVMLNGNVLGYLRVSHPWFEVTK
PARQLFIDLSLGTSLLVGLVAMTGWFLSGLAIEPIQDSYQHLKQFTADASHELRNPIALIQTNVQVALADPELEMPEQRQ
QLEVIERLTQRLGRLVDDLLFLARQDSGMLEIDYQPCPLDAVLMEVVEDQRALATSKGVHLHLHLEETGAETVPSEEPFS
VIGDYDQLVRLFTNLVSNGIQYTPAEGRVRVTLKQSLRQGIPYLKAMVEDEGLGIPAEAIPHVFDRFYRADPARQRSLIP
ATQQPVSSGKVMGTGLGLAIAQAICHNHQGQMSVSSRLQQGTLFTVTLPQQLSRKIDVKSAPSEEINQLP

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=32.9457364341085, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786600, Length=254, Percent_Identity=29.1338582677165, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=29.5719844357977, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=30.078125, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=29.7959183673469, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=25.7462686567164, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=253, Percent_Identity=25.6916996047431, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=298, Percent_Identity=26.1744966442953, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=308, Percent_Identity=24.3506493506494, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=259, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=261, Percent_Identity=24.5210727969349, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=25.4826254826255, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789403, Length=241, Percent_Identity=29.4605809128631, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52434; Mature: 52434

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTTRRRLALWYTGVTAILLLVFASGFYLYVRGTLIERVDDTLSHVVEVVQRSLVVEAS
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEC
NADLSPLDSPFIVNLEASFGDPPDAVDDDRIDLEWFSAEGDLLWSTLSEVLEVPIRLGYR
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GETVEIADDYLLRQLTQRVMLNGNVLGYLRVSHPWFEVTKPARQLFIDLSLGTSLLVGLV
CCEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHEEEHHHHHHHHHHHH
AMTGWFLSGLAIEPIQDSYQHLKQFTADASHELRNPIALIQTNVQVALADPELEMPEQRQ
HHHHHHHHCCEECCHHHHHHHHHHHHCCHHHHHHCCEEEEEECCEEEEECCCCCCCHHHH
QLEVIERLTQRLGRLVDDLLFLARQDSGMLEIDYQPCPLDAVLMEVVEDQRALATSKGVH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
LHLHLEETGAETVPSEEPFSVIGDYDQLVRLFTNLVSNGIQYTPAEGRVRVTLKQSLRQG
EEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCEECCCCCEEEEHHHHHHHHC
IPYLKAMVEDEGLGIPAEAIPHVFDRFYRADPARQRSLIPATQQPVSSGKVMGTGLGLAI
CHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEECHHHHHH
AQAICHNHQGQMSVSSRLQQGTLFTVTLPQQLSRKIDVKSAPSEEINQLP
HHHHHHCCCCCCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MFQTTRRRLALWYTGVTAILLLVFASGFYLYVRGTLIERVDDTLSHVVEVVQRSLVVEAS
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEC
NADLSPLDSPFIVNLEASFGDPPDAVDDDRIDLEWFSAEGDLLWSTLSEVLEVPIRLGYR
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GETVEIADDYLLRQLTQRVMLNGNVLGYLRVSHPWFEVTKPARQLFIDLSLGTSLLVGLV
CCEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHEEEHHHHHHHHHHHH
AMTGWFLSGLAIEPIQDSYQHLKQFTADASHELRNPIALIQTNVQVALADPELEMPEQRQ
HHHHHHHHCCEECCHHHHHHHHHHHHCCHHHHHHCCEEEEEECCEEEEECCCCCCCHHHH
QLEVIERLTQRLGRLVDDLLFLARQDSGMLEIDYQPCPLDAVLMEVVEDQRALATSKGVH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
LHLHLEETGAETVPSEEPFSVIGDYDQLVRLFTNLVSNGIQYTPAEGRVRVTLKQSLRQG
EEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCEECCCCCEEEEHHHHHHHHC
IPYLKAMVEDEGLGIPAEAIPHVFDRFYRADPARQRSLIPATQQPVSSGKVMGTGLGLAI
CHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEECHHHHHH
AQAICHNHQGQMSVSSRLQQGTLFTVTLPQQLSRKIDVKSAPSEEINQLP
HHHHHHCCCCCCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]