Click here to switch to the map view.

The map label for this gene is surE

Identifier: 158335799

GI number: 158335799

Start: 2691663

End: 2692469

Strand: Direct

Name: surE

Synonym: AM1_2650

Alternate gene names: 158335799

Gene position: 2691663-2692469 (Clockwise)

Preceding gene: 158335795

Following gene: 158335800

Centisome position: 41.39

GC content: 48.95

Gene sequence:

>807_bases
ATGAAAATCTTAGTTGGCAATGATGATGGTATTTTTGCCCCCGGTGTCAGGGCCTTAGCCAATACCCTCGCCCCAGACCA
TGAGGTCACCGTTGTTTGCCCAGATCGAGAACGCTCAGCCACCGGACATGGGCTCACCATCCATCAGCCGATTCGTGCCG
AACAAGTACAGTCCATGTTTGTAGATCAGGTCACTGCCTGGGCCTGTTCTGGTACGCCTGCAGACTGTATCAAGTTAGCC
CTAGGCGCACTCCTAGACAGTCCACCAGATTTCGTCTTGTCGGGGATTAATCAAGGCCCCAATTTAGGCACAGACGTCCT
GTACTCAGGGACGGTCTCAGCAGCCATGGAAGGAGTCATTGAAGGAATTACGAGTATTGCCTTTAGTTATAGCAGCTTTA
CAGACCAACAGTTTCAGCCAGCGGCTAATTTTGGCCAGCAGTTATTAGAACATCTGATTCAGCATCCTTTATCGGAGCCT
ATGTTGTTAAATGTGAATGTCCCTGCTGTACCTGCCGATCAGATTCAAGGGGTTGCCCTCACTCGTCAGGGGATCCGTCG
TTACCATGACCTATTCGAAAAACGAATCGATCCAAGAGGAAAAACGTATTATTGGCTGGCGGGAGAAGTGATGGAAGATT
TAGAAGACGATAGGATGGCCGATCCATTTGTCCTCACAGATGTTCAGGCGATTCGTCAACGATGCATTGCGATCACGCCT
TTGCAATATAATCTGACTGCGAACAATAGTCTAAATCCTTTATTGGCCTGGCTTACACCCCTCCAGAAACGCCAATCCGT
GATTTGA

Upstream 100 bases:

>100_bases
AACATCAATCCAGCAGTCTTCATCTGTAAGATGCAAGCAGCATCGTTAATATACAATCCTGCACAAGCAATCGAGCTGTC
TTTGTCTTCATCGGAGGTCC

Downstream 100 bases:

>100_bases
TCACACGAATTGTTCTTATTTGGGCTAAAATTCACAGAAACCCGCAGAAGTTTCATTGCTTCGATATGATTGGACTAACG
GCCGATTCGGTCCAGGCCAT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMFVDQVTAWACSGTPADCIKLA
LGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVIEGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEP
MLLNVNVPAVPADQIQGVALTRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITP
LQYNLTANNSLNPLLAWLTPLQKRQSVI

Sequences:

>Translated_268_residues
MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMFVDQVTAWACSGTPADCIKLA
LGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVIEGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEP
MLLNVNVPAVPADQIQGVALTRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITP
LQYNLTANNSLNPLLAWLTPLQKRQSVI
>Mature_268_residues
MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMFVDQVTAWACSGTPADCIKLA
LGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVIEGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEP
MLLNVNVPAVPADQIQGVALTRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITP
LQYNLTANNSLNPLLAWLTPLQKRQSVI

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:
GO:0000166: 5'/3'-nucleotidase SurE
GO:0005737: 5'/3'-nucleotidase SurE
GO:0016787: 5'/3'-nucleotidase SurE
GO:0046872: 5'/3'-nucleotidase SurE

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=258, Percent_Identity=38.7596899224806, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319570, Length=323, Percent_Identity=24.4582043343653, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ACAM1 (B0C6V3)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001516973.1
- ProteinModelPortal:   B0C6V3
- GeneID:   5681462
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_2650
- HOGENOM:   HBG600532
- OMA:   KHTASAG
- ProtClustDB:   PRK00346
- BioCyc:   AMAR329726:AM1_2650-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 29333; Mature: 29333

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMF
CEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHH
VDQVTAWACSGTPADCIKLALGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVI
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHEECCHHHHHHHHHH
EGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEPMLLNVNVPAVPADQIQGVAL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
TRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITP
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECC
LQYNLTANNSLNPLLAWLTPLQKRQSVI
EEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMF
CEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHH
VDQVTAWACSGTPADCIKLALGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVI
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHEECCHHHHHHHHHH
EGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEPMLLNVNVPAVPADQIQGVAL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
TRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITP
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECC
LQYNLTANNSLNPLLAWLTPLQKRQSVI
EEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA