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The map label for this gene is speA [H]

Identifier: 158335783

GI number: 158335783

Start: 2672099

End: 2673553

Strand: Direct

Name: speA [H]

Synonym: AM1_2634

Alternate gene names: 158335783

Gene position: 2672099-2673553 (Clockwise)

Preceding gene: 158339484

Following gene: 158335784

Centisome position: 41.09

GC content: 49.62

Gene sequence:

>1455_bases
ATGAGCGTGAATCAACAGCAAGTTCCCTTATGGCAAGCGCTACAGGACAGTGCCCACTCAAATCAAATTGCGTTCCACAC
CCCTGGCCATAAACGAGGGCGGGGGCTGCCCGCTGCGATTCTGCAGCACTTTGGATCCGCTCTAGGTTCAGCCGATCTGC
CTGAACTACCTGAATTAGATAATCTCTTTGCCCCTGAAGCAGCCATTCTAGAGGCTCAGGTACTCGCTGCTCAACTCTTT
GGGGCTGAGCAGACCTGGTTTTTAACCAACGGGTCGACCTGTGGGATTCTGGCAGCATTGCTAACCGTCTGTGGCCCAGG
TGCTCAGATTATCGTGCCGAGGAATCTCCATACATCTGTAATTTCTGGGCTAGTACTGTCTGGCGCAGTCCCCATTTTTG
TACAACCGACCTTGGATAGCCAGCTCAACTTAGCCCATAGTTTATCGGTTCAGGATGTTCAGCTGGCGTTCGAGACATAT
CCTCAGACTAAGGCTATCTTCTTAATCCATCCAACCTATGAAGGGGTTTGTGGAGATGTATCGGCTATCGCTACGTTTGC
CCATGATCATGACATTCCGTTGATTGTCGATGAAGCCCATGGTCCCCATTTTGCTTTTCATCCTCAATTCCCTCAATCTG
CTCTCGCCGCAGGTGCAGACCTGGTTGTACAATCCACCCACAAAATGCTAGGAGCCTTGACACAAGCGGCCATGCTGCAT
GTTCAGGGTCTTCTCATCGATCGAAAACGGCTGAGCCAAACCCTACAGCTCGTGCAATCTACCAGTCCTAATTATCTGCT
TCTGGCCTCTTTAGATGCTACCCGCCACCAATTAGCCCATGCTGGCCTGAACGTCATGGAGCAGGTCTTAACTCTGGCCA
ATAAAGCCCATACTCAACTGAACCATTTGCCCAACTATCGTCCATGGGATCCAATAGGCACTACCCCTGGCTGTATTGCC
CTCGATCAGACACGCCTAACCATTCCTATTGAGCCATTTGGTGACCAGGCCTATGACCTCGATCAAACCCTCATTGATAC
CTATCGCATCTCAGCAGAGCTGATCACGCCAGACCATCTCACCTTCTTAATTACATTGGGCAATACTGAGGATGATATTG
ACCAATTACTCTGCGCATTACGAGAGTTATACCACCCTCCTTTACATCCCAGCTCTCTGGCCTACTCAACAAACAAACTA
CCTATTGCTTTACCCGTGCTATCGCCCAGGGAGGCCTATTGGTATTCTTCAGAAGTCGTTCCAGTTCTCAAGGCCGTCGA
CCGGATCAGTACCGAAAGTATTTGTCCCTATCCACCGGGCATCCCTATTCTGCTTCCTGGAGAAAGAATTCAGAAACAAG
ATTTAGACTGGCTATTACAACTCAAACAACAAGGAGGCATCATTACAGGGTGTAGCGATCTGCGCTTTCAGACCTTAAAG
GTTGTGAGAGAGTAG

Upstream 100 bases:

>100_bases
ATGGGCTCAAACACATTATGAAGACAACATAAGCATCTCTAAAAGTGATGCAAATGTGACTCATAATCCTTTGCCATTAA
AACATGCATAAACCCTTTAC

Downstream 100 bases:

>100_bases
TACCGTGAGCACACTGGGACAACCTATGCCTTCTTCTCCTTGGCCCTATACCAGTCCTGGCATTCCAGATGAACTGTTTG
AGCGTTTACCTGGAATCCCC

Product: Orn/Lys/Arg decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSVNQQQVPLWQALQDSAHSNQIAFHTPGHKRGRGLPAAILQHFGSALGSADLPELPELDNLFAPEAAILEAQVLAAQLF
GAEQTWFLTNGSTCGILAALLTVCGPGAQIIVPRNLHTSVISGLVLSGAVPIFVQPTLDSQLNLAHSLSVQDVQLAFETY
PQTKAIFLIHPTYEGVCGDVSAIATFAHDHDIPLIVDEAHGPHFAFHPQFPQSALAAGADLVVQSTHKMLGALTQAAMLH
VQGLLIDRKRLSQTLQLVQSTSPNYLLLASLDATRHQLAHAGLNVMEQVLTLANKAHTQLNHLPNYRPWDPIGTTPGCIA
LDQTRLTIPIEPFGDQAYDLDQTLIDTYRISAELITPDHLTFLITLGNTEDDIDQLLCALRELYHPPLHPSSLAYSTNKL
PIALPVLSPREAYWYSSEVVPVLKAVDRISTESICPYPPGIPILLPGERIQKQDLDWLLQLKQQGGIITGCSDLRFQTLK
VVRE

Sequences:

>Translated_484_residues
MSVNQQQVPLWQALQDSAHSNQIAFHTPGHKRGRGLPAAILQHFGSALGSADLPELPELDNLFAPEAAILEAQVLAAQLF
GAEQTWFLTNGSTCGILAALLTVCGPGAQIIVPRNLHTSVISGLVLSGAVPIFVQPTLDSQLNLAHSLSVQDVQLAFETY
PQTKAIFLIHPTYEGVCGDVSAIATFAHDHDIPLIVDEAHGPHFAFHPQFPQSALAAGADLVVQSTHKMLGALTQAAMLH
VQGLLIDRKRLSQTLQLVQSTSPNYLLLASLDATRHQLAHAGLNVMEQVLTLANKAHTQLNHLPNYRPWDPIGTTPGCIA
LDQTRLTIPIEPFGDQAYDLDQTLIDTYRISAELITPDHLTFLITLGNTEDDIDQLLCALRELYHPPLHPSSLAYSTNKL
PIALPVLSPREAYWYSSEVVPVLKAVDRISTESICPYPPGIPILLPGERIQKQDLDWLLQLKQQGGIITGCSDLRFQTLK
VVRE
>Mature_483_residues
SVNQQQVPLWQALQDSAHSNQIAFHTPGHKRGRGLPAAILQHFGSALGSADLPELPELDNLFAPEAAILEAQVLAAQLFG
AEQTWFLTNGSTCGILAALLTVCGPGAQIIVPRNLHTSVISGLVLSGAVPIFVQPTLDSQLNLAHSLSVQDVQLAFETYP
QTKAIFLIHPTYEGVCGDVSAIATFAHDHDIPLIVDEAHGPHFAFHPQFPQSALAAGADLVVQSTHKMLGALTQAAMLHV
QGLLIDRKRLSQTLQLVQSTSPNYLLLASLDATRHQLAHAGLNVMEQVLTLANKAHTQLNHLPNYRPWDPIGTTPGCIAL
DQTRLTIPIEPFGDQAYDLDQTLIDTYRISAELITPDHLTFLITLGNTEDDIDQLLCALRELYHPPLHPSSLAYSTNKLP
IALPVLSPREAYWYSSEVVPVLKAVDRISTESICPYPPGIPILLPGERIQKQDLDWLLQLKQQGGIITGCSDLRFQTLKV
VRE

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=559, Percent_Identity=23.9713774597496, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790573, Length=590, Percent_Identity=23.3898305084746, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI221142684, Length=327, Percent_Identity=26.9113149847095, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786909, Length=347, Percent_Identity=27.6657060518732, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082193, Length=388, Percent_Identity=25.2577319587629, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 52771; Mature: 52640

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNQQQVPLWQALQDSAHSNQIAFHTPGHKRGRGLPAAILQHFGSALGSADLPELPELD
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
NLFAPEAAILEAQVLAAQLFGAEQTWFLTNGSTCGILAALLTVCGPGAQIIVPRNLHTSV
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCHHHHH
ISGLVLSGAVPIFVQPTLDSQLNLAHSLSVQDVQLAFETYPQTKAIFLIHPTYEGVCGDV
HHHHHHHCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
SAIATFAHDHDIPLIVDEAHGPHFAFHPQFPQSALAAGADLVVQSTHKMLGALTQAAMLH
HHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VQGLLIDRKRLSQTLQLVQSTSPNYLLLASLDATRHQLAHAGLNVMEQVLTLANKAHTQL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHLPNYRPWDPIGTTPGCIALDQTRLTIPIEPFGDQAYDLDQTLIDTYRISAELITPDHL
HCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHEEEEEECCCCE
TFLITLGNTEDDIDQLLCALRELYHPPLHPSSLAYSTNKLPIALPVLSPREAYWYSSEVV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHEECCCHH
PVLKAVDRISTESICPYPPGIPILLPGERIQKQDLDWLLQLKQQGGIITGCSDLRFQTLK
HHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHH
VVRE
HHCC
>Mature Secondary Structure 
SVNQQQVPLWQALQDSAHSNQIAFHTPGHKRGRGLPAAILQHFGSALGSADLPELPELD
CCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
NLFAPEAAILEAQVLAAQLFGAEQTWFLTNGSTCGILAALLTVCGPGAQIIVPRNLHTSV
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCHHHHH
ISGLVLSGAVPIFVQPTLDSQLNLAHSLSVQDVQLAFETYPQTKAIFLIHPTYEGVCGDV
HHHHHHHCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
SAIATFAHDHDIPLIVDEAHGPHFAFHPQFPQSALAAGADLVVQSTHKMLGALTQAAMLH
HHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VQGLLIDRKRLSQTLQLVQSTSPNYLLLASLDATRHQLAHAGLNVMEQVLTLANKAHTQL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHLPNYRPWDPIGTTPGCIALDQTRLTIPIEPFGDQAYDLDQTLIDTYRISAELITPDHL
HCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHEEEEEECCCCE
TFLITLGNTEDDIDQLLCALRELYHPPLHPSSLAYSTNKLPIALPVLSPREAYWYSSEVV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHEECCCHH
PVLKAVDRISTESICPYPPGIPILLPGERIQKQDLDWLLQLKQQGGIITGCSDLRFQTLK
HHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHH
VVRE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]