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The map label for this gene is aspC [H]

Identifier: 158335770

GI number: 158335770

Start: 2661461

End: 2662630

Strand: Direct

Name: aspC [H]

Synonym: AM1_2621

Alternate gene names: 158335770

Gene position: 2661461-2662630 (Clockwise)

Preceding gene: 158335769

Following gene: 158335771

Centisome position: 40.92

GC content: 49.91

Gene sequence:

>1170_bases
ATGAAACTGGCAGACCGCATTGGTCAGGTGTCTGCATCTTTGACCTTAGCCATCTCAGCAAAAGCAAAAGCAATGCGGGC
TGACGGTATTGATGTTTTAAGTTTTAGTGCTGGCGAACCCGATTTTGATACCCCTGATCACATCAAAGCTGCTGCGAAGC
AAGCTTTAGATCAAGGAAAAACCAAGTATGGCCCTGCACCAGGCGAGCCCCAACTACGAGCAGCCATTGCCCATAAATTA
CAGCAAGAAAATCGCTTAAATTTCCAAACAGAGAACGTGCTGGTGACAAACGGGGGCAAGCAATCTCTCTATAACTTAAT
GCAGGTTCTTCTCAATCCTGGTGATGAGGTGCTTATTCCCGCCCCCTACTGGCTCAGTTATCCCGAAATGGTGAAATTGG
CTGGAGGAGTCCCAATCACTCTAGCCACTGATGCTCAAACTGGATTTAAAATCACGCCTGCCCAACTGCAAGCAGCTATC
ACCCCCCAGACGCGTCTTTTAATCCTCAATTCTCCTTCTAATCCCACGGGAATGGTCTACACCCCGGCCGAAATTGCGGC
CCTAGCAGAGATTATTGTGGCGGCCAATATTTGGGTCGTATCAGACGAAATCTACGAGAGAATTTTATATGATGGCGCTG
AACAGCTGAGTATAGGCGCAGTGAGTGAGGCCGCCTTTCAACACACGATTATCAGCAATGGATTTGCCAAAGCATATTCA
ATGACCGGATGGCGGATTGGGTATCTTGCGGGTCCATTAGAGCTGATTCGAGCCGTGGGGCGCTTGCAAAGCCACAGTAC
GTCTAATGTTTGCACCTTTGCACAGTATGGTGCCATCGCCGCCCTTGAAGGGTCGCAAGATTGCGTAGAAACCATGCGCA
AAGCCTTTGATCAACGGCGTCAGTTGATGTTTCAGCTTTTGACGGCTATTCCCGGCGTCACCTGCCCCCAGCCGCAAGGA
GCATTTTATATGTTTCCGGATATTAGCTTTACAGGGTTAGGATCGATTGCATTTTGCGAAGCCTTGCTGGAACAGTGTCA
TGTAGCGGCTGTGCCTGGCATTGCCTTCGGGGCCGACCAATGCATTCGGCTATCCTACGCCACTGACCAAACGAGTATCG
AACAAGGCATCGAACGGCTGGCCCAATTTATCACCACCGTTAGCCGCTAA

Upstream 100 bases:

>100_bases
AGAAGAAGATTCAATTCTTAAGAGGGAATTCTGATTTGCTCCTTCAGAGGGTGCGGTATGCTATTCCAAATAGCCCCCCG
TCCTCAATCTCGGAGTCAGC

Downstream 100 bases:

>100_bases
ATTCTATCTCTTGAGCCCTTCTATCTACCTGAAAGTGGCGCGCACATAGCTCTCAAGCCCCAACAAATGTGTCAAAGCTT
AGCAATCTCCGCCGTTGTTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKLADRIGQVSASLTLAISAKAKAMRADGIDVLSFSAGEPDFDTPDHIKAAAKQALDQGKTKYGPAPGEPQLRAAIAHKL
QQENRLNFQTENVLVTNGGKQSLYNLMQVLLNPGDEVLIPAPYWLSYPEMVKLAGGVPITLATDAQTGFKITPAQLQAAI
TPQTRLLILNSPSNPTGMVYTPAEIAALAEIIVAANIWVVSDEIYERILYDGAEQLSIGAVSEAAFQHTIISNGFAKAYS
MTGWRIGYLAGPLELIRAVGRLQSHSTSNVCTFAQYGAIAALEGSQDCVETMRKAFDQRRQLMFQLLTAIPGVTCPQPQG
AFYMFPDISFTGLGSIAFCEALLEQCHVAAVPGIAFGADQCIRLSYATDQTSIEQGIERLAQFITTVSR

Sequences:

>Translated_389_residues
MKLADRIGQVSASLTLAISAKAKAMRADGIDVLSFSAGEPDFDTPDHIKAAAKQALDQGKTKYGPAPGEPQLRAAIAHKL
QQENRLNFQTENVLVTNGGKQSLYNLMQVLLNPGDEVLIPAPYWLSYPEMVKLAGGVPITLATDAQTGFKITPAQLQAAI
TPQTRLLILNSPSNPTGMVYTPAEIAALAEIIVAANIWVVSDEIYERILYDGAEQLSIGAVSEAAFQHTIISNGFAKAYS
MTGWRIGYLAGPLELIRAVGRLQSHSTSNVCTFAQYGAIAALEGSQDCVETMRKAFDQRRQLMFQLLTAIPGVTCPQPQG
AFYMFPDISFTGLGSIAFCEALLEQCHVAAVPGIAFGADQCIRLSYATDQTSIEQGIERLAQFITTVSR
>Mature_389_residues
MKLADRIGQVSASLTLAISAKAKAMRADGIDVLSFSAGEPDFDTPDHIKAAAKQALDQGKTKYGPAPGEPQLRAAIAHKL
QQENRLNFQTENVLVTNGGKQSLYNLMQVLLNPGDEVLIPAPYWLSYPEMVKLAGGVPITLATDAQTGFKITPAQLQAAI
TPQTRLLILNSPSNPTGMVYTPAEIAALAEIIVAANIWVVSDEIYERILYDGAEQLSIGAVSEAAFQHTIISNGFAKAYS
MTGWRIGYLAGPLELIRAVGRLQSHSTSNVCTFAQYGAIAALEGSQDCVETMRKAFDQRRQLMFQLLTAIPGVTCPQPQG
AFYMFPDISFTGLGSIAFCEALLEQCHVAAVPGIAFGADQCIRLSYATDQTSIEQGIERLAQFITTVSR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=368, Percent_Identity=25.8152173913043, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI56713256, Length=318, Percent_Identity=26.4150943396226, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI95147551, Length=423, Percent_Identity=24.5862884160757, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI169881279, Length=423, Percent_Identity=24.5862884160757, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=22.4422442244224, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=24, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI149944424, Length=223, Percent_Identity=26.0089686098655, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1786816, Length=388, Percent_Identity=28.6082474226804, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=29.3969849246231, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=31.7708333333333, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787909, Length=403, Percent_Identity=23.3250620347395, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=298, Percent_Identity=23.489932885906, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=285, Percent_Identity=29.4736842105263, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=285, Percent_Identity=29.4736842105263, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=331, Percent_Identity=26.2839879154079, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=385, Percent_Identity=23.8961038961039, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=25.0632911392405, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=338, Percent_Identity=23.6686390532544, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573069, Length=253, Percent_Identity=30.8300395256917, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24646114, Length=253, Percent_Identity=30.8300395256917, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573067, Length=253, Percent_Identity=30.8300395256917, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573065, Length=253, Percent_Identity=30.8300395256917, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=23.015873015873, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41859; Mature: 41859

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLADRIGQVSASLTLAISAKAKAMRADGIDVLSFSAGEPDFDTPDHIKAAAKQALDQGK
CCHHHHHHHHCCEEEEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYGPAPGEPQLRAAIAHKLQQENRLNFQTENVLVTNGGKQSLYNLMQVLLNPGDEVLIP
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECEEEEECCCHHHHHHHHHHHHCCCCCEEEC
APYWLSYPEMVKLAGGVPITLATDAQTGFKITPAQLQAAITPQTRLLILNSPSNPTGMVY
CCHHCCCHHHHHHCCCCEEEEEECCCCCCEECHHHHHEEECCCEEEEEEECCCCCCEEEE
TPAEIAALAEIIVAANIWVVSDEIYERILYDGAEQLSIGAVSEAAFQHTIISNGFAKAYS
CHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHH
MTGWRIGYLAGPLELIRAVGRLQSHSTSNVCTFAQYGAIAALEGSQDCVETMRKAFDQRR
CCCEEEHHHHCHHHHHHHHHHHHCCCCCCCEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
QLMFQLLTAIPGVTCPQPQGAFYMFPDISFTGLGSIAFCEALLEQCHVAAVPGIAFGADQ
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
CIRLSYATDQTSIEQGIERLAQFITTVSR
EEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLADRIGQVSASLTLAISAKAKAMRADGIDVLSFSAGEPDFDTPDHIKAAAKQALDQGK
CCHHHHHHHHCCEEEEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYGPAPGEPQLRAAIAHKLQQENRLNFQTENVLVTNGGKQSLYNLMQVLLNPGDEVLIP
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEECEEEEECCCHHHHHHHHHHHHCCCCCEEEC
APYWLSYPEMVKLAGGVPITLATDAQTGFKITPAQLQAAITPQTRLLILNSPSNPTGMVY
CCHHCCCHHHHHHCCCCEEEEEECCCCCCEECHHHHHEEECCCEEEEEEECCCCCCEEEE
TPAEIAALAEIIVAANIWVVSDEIYERILYDGAEQLSIGAVSEAAFQHTIISNGFAKAYS
CHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCHHHHHH
MTGWRIGYLAGPLELIRAVGRLQSHSTSNVCTFAQYGAIAALEGSQDCVETMRKAFDQRR
CCCEEEHHHHCHHHHHHHHHHHHCCCCCCCEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
QLMFQLLTAIPGVTCPQPQGAFYMFPDISFTGLGSIAFCEALLEQCHVAAVPGIAFGADQ
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
CIRLSYATDQTSIEQGIERLAQFITTVSR
EEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]