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The map label for this gene is fkpB [C]

Identifier: 158335766

GI number: 158335766

Start: 2656832

End: 2657260

Strand: Direct

Name: fkpB [C]

Synonym: AM1_2617

Alternate gene names: 158335766

Gene position: 2656832-2657260 (Clockwise)

Preceding gene: 158335765

Following gene: 158335768

Centisome position: 40.85

GC content: 48.95

Gene sequence:

>429_bases
ATGGCAGCCGCTAAAGTCGGAGACACCGTATCAATTCACTACACGGGAAAGCTGGATGATGGTTCCGTCTTCGACTCTTC
TTTAGAGCGCGAGCCTTTAAAATTCTCCATTGGGGGACAGCAAGTTATTCCAGGATTTGAGCAAGCCGTTATCGGCATGA
ACCCCGGTGAGTCCAAAACCGAGACGATTGTCTGCGATCAAGCCTATGGTCCCCGCCATGAAGATATGGTAGTCACCGTC
CTCCGGGAGCAAATTCCCAGCGATTTCGACTTAGAAGTGGGGCAACAATTGCAGATCAGAAACCCCGAGGGACAAGTCAT
TCCGGTGATGGTCAGTGAGATTATTGAAGATCAAGTCACCCTAGATGGCAATCATCCCCTAGCCGGTGAAGATTTAACCT
TTGAGATTGAGTTAGTCAGCATTGCATAA

Upstream 100 bases:

>100_bases
GTGGCCGTAGGTAGACAAAGGTGTTCATTACACTTGTGACCCAGTGGGCAAATAACGCGTTAGTCCACTGGTGCTGTTCA
TTCATCTCAGGAGCATAATT

Downstream 100 bases:

>100_bases
TTCCCTCATTTATCTCAGGGAGAAGGGTTTGAGGTAGCAAGGGGCACCAGTAACAAGCTGCCCTTCTTTGACTCCGAATT
AAACCGCCAATATTGCTGAT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAAAKVGDTVSIHYTGKLDDGSVFDSSLEREPLKFSIGGQQVIPGFEQAVIGMNPGESKTETIVCDQAYGPRHEDMVVTV
LREQIPSDFDLEVGQQLQIRNPEGQVIPVMVSEIIEDQVTLDGNHPLAGEDLTFEIELVSIA

Sequences:

>Translated_142_residues
MAAAKVGDTVSIHYTGKLDDGSVFDSSLEREPLKFSIGGQQVIPGFEQAVIGMNPGESKTETIVCDQAYGPRHEDMVVTV
LREQIPSDFDLEVGQQLQIRNPEGQVIPVMVSEIIEDQVTLDGNHPLAGEDLTFEIELVSIA
>Mature_141_residues
AAAKVGDTVSIHYTGKLDDGSVFDSSLEREPLKFSIGGQQVIPGFEQAVIGMNPGESKTETIVCDQAYGPRHEDMVVTVL
REQIPSDFDLEVGQQLQIRNPEGQVIPVMVSEIIEDQVTLDGNHPLAGEDLTFEIELVSIA

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706131, Length=69, Percent_Identity=49.2753623188406, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI219842220, Length=69, Percent_Identity=49.2753623188406, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI206725530, Length=70, Percent_Identity=45.7142857142857, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI17149844, Length=70, Percent_Identity=45.7142857142857, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI17149842, Length=70, Percent_Identity=45.7142857142857, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI17149836, Length=67, Percent_Identity=49.2537313432836, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI4503725, Length=67, Percent_Identity=49.2537313432836, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1786211, Length=133, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789748, Length=132, Percent_Identity=32.5757575757576, Blast_Score=68, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356629, Length=61, Percent_Identity=49.1803278688525, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15439; Mature: 15307

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAKVGDTVSIHYTGKLDDGSVFDSSLEREPLKFSIGGQQVIPGFEQAVIGMNPGESKT
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEECCCCHHEEEECCCCCCCC
ETIVCDQAYGPRHEDMVVTVLREQIPSDFDLEVGQQLQIRNPEGQVIPVMVSEIIEDQVT
EEEEEECCCCCCCCCHHHEEHHHHCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCEE
LDGNHPLAGEDLTFEIELVSIA
ECCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
AAAKVGDTVSIHYTGKLDDGSVFDSSLEREPLKFSIGGQQVIPGFEQAVIGMNPGESKT
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEECCCCHHEEEECCCCCCCC
ETIVCDQAYGPRHEDMVVTVLREQIPSDFDLEVGQQLQIRNPEGQVIPVMVSEIIEDQVT
EEEEEECCCCCCCCCHHHEEHHHHCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCEE
LDGNHPLAGEDLTFEIELVSIA
ECCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]