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The map label for this gene is ubiE [C]

Identifier: 158335755

GI number: 158335755

Start: 2642757

End: 2643548

Strand: Reverse

Name: ubiE [C]

Synonym: AM1_2606

Alternate gene names: 158335755

Gene position: 2643548-2642757 (Counterclockwise)

Preceding gene: 158335756

Following gene: 158335754

Centisome position: 40.65

GC content: 48.11

Gene sequence:

>792_bases
ATGTCGACTGCTAAATACATTTTCACTGAGACTCAATATGCTCAGGAACTGAAACGCCTCCAGGCCATTGAAAAAATCTT
TGATCCAACCAGTCATCAACGGCTGAAATCGACAGGGATAAACACAAACTGGCGATGCTTAGAAGTTGGAGCTGGAGCAG
GATCGATCACGCAATGGATGGCAGGCATGGTTGGGGAGAAGGGCCAGGTGGTTGCCGTTGATCTTGATACGCGATTTGTG
GCTAACCTGGAAGCCGGAAATGTTGAGGTTGTGGAAGGCGATATCCAGCACCTTCCTTTGGATAAACAATCCTTTGATTT
GGTTCATGCCCGCTATGTTTTGATTCATAATCCTGATGCTCATGCATTCCTATCGAAGCTGTTGGAGTTGGTGAAACCGG
GGGGATGGATCGTCCTAGAAGAACCTGACTTTGCGGCTGCTCGGGCGATTGCAGGTGAGGACTCTGCTTGTCAGTCTGTT
AATAATGTCAACCGGGCGATTGAGCAGATGTTTACGGCGAGGGGGATGGATTATGGCCTTGGAGCTAAGTTACCTGCTCT
ACTACAATCCTATGATTTACAGTCATTCTCGGTTGAGGTTGATACTCATCTCTCTCAAGGGGGTTCAGGCATAGCGACTA
TGATGCATATGTCTACGATGCAATTGGCAGAGAAATATCTTGCAACGGGGGCAGTTACCCAGGCGGATATCGATCATTAT
GGCCGATTCGCAGAAGACCCAAATACGTGGGCCATTTACTATGCGACGGTAGGCGTTGTTGCTCAGAAATAG

Upstream 100 bases:

>100_bases
CTTTGCTATGTACTGATGGGAGCGAGGGATAACGGTTTATGGGATTGCTCTCATTAGATATATGGTTTGCCCAGGACTAG
ATGGCTGAGCGGAGAAAGAA

Downstream 100 bases:

>100_bases
TAGTTTAACTTTGGCAATATGGCTAAGCTAAGGACTGCTTGTGGACTTGCACAGAGTGCTATTAGATCATTTCATGCCTT
ATCTTGCCTGTTAGCACTGG

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase Type; Ubiquinone/Menaquinone Biosynthesis Methylase-Like Protein; Ribosomal RNA Adenine Methylase Transferase; Demethylmenaquinone Methyltransferase; AMP-Dependent Synthetase And Ligase; Menaquinone Biosynthesis Methyltransferase

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSTAKYIFTETQYAQELKRLQAIEKIFDPTSHQRLKSTGINTNWRCLEVGAGAGSITQWMAGMVGEKGQVVAVDLDTRFV
ANLEAGNVEVVEGDIQHLPLDKQSFDLVHARYVLIHNPDAHAFLSKLLELVKPGGWIVLEEPDFAAARAIAGEDSACQSV
NNVNRAIEQMFTARGMDYGLGAKLPALLQSYDLQSFSVEVDTHLSQGGSGIATMMHMSTMQLAEKYLATGAVTQADIDHY
GRFAEDPNTWAIYYATVGVVAQK

Sequences:

>Translated_263_residues
MSTAKYIFTETQYAQELKRLQAIEKIFDPTSHQRLKSTGINTNWRCLEVGAGAGSITQWMAGMVGEKGQVVAVDLDTRFV
ANLEAGNVEVVEGDIQHLPLDKQSFDLVHARYVLIHNPDAHAFLSKLLELVKPGGWIVLEEPDFAAARAIAGEDSACQSV
NNVNRAIEQMFTARGMDYGLGAKLPALLQSYDLQSFSVEVDTHLSQGGSGIATMMHMSTMQLAEKYLATGAVTQADIDHY
GRFAEDPNTWAIYYATVGVVAQK
>Mature_262_residues
STAKYIFTETQYAQELKRLQAIEKIFDPTSHQRLKSTGINTNWRCLEVGAGAGSITQWMAGMVGEKGQVVAVDLDTRFVA
NLEAGNVEVVEGDIQHLPLDKQSFDLVHARYVLIHNPDAHAFLSKLLELVKPGGWIVLEEPDFAAARAIAGEDSACQSVN
NVNRAIEQMFTARGMDYGLGAKLPALLQSYDLQSFSVEVDTHLSQGGSGIATMMHMSTMQLAEKYLATGAVTQADIDHYG
RFAEDPNTWAIYYATVGVVAQK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28799; Mature: 28668

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAKYIFTETQYAQELKRLQAIEKIFDPTSHQRLKSTGINTNWRCLEVGAGAGSITQWM
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
AGMVGEKGQVVAVDLDTRFVANLEAGNVEVVEGDIQHLPLDKQSFDLVHARYVLIHNPDA
HHHCCCCCCEEEEECCCEEEEEECCCCEEEEECCHHHCCCCCCHHHEEEEEEEEEECCCH
HAFLSKLLELVKPGGWIVLEEPDFAAARAIAGEDSACQSVNNVNRAIEQMFTARGMDYGL
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GAKLPALLQSYDLQSFSVEVDTHLSQGGSGIATMMHMSTMQLAEKYLATGAVTQADIDHY
CCHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GRFAEDPNTWAIYYATVGVVAQK
CCCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
STAKYIFTETQYAQELKRLQAIEKIFDPTSHQRLKSTGINTNWRCLEVGAGAGSITQWM
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
AGMVGEKGQVVAVDLDTRFVANLEAGNVEVVEGDIQHLPLDKQSFDLVHARYVLIHNPDA
HHHCCCCCCEEEEECCCEEEEEECCCCEEEEECCHHHCCCCCCHHHEEEEEEEEEECCCH
HAFLSKLLELVKPGGWIVLEEPDFAAARAIAGEDSACQSVNNVNRAIEQMFTARGMDYGL
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GAKLPALLQSYDLQSFSVEVDTHLSQGGSGIATMMHMSTMQLAEKYLATGAVTQADIDHY
CCHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GRFAEDPNTWAIYYATVGVVAQK
CCCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA