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The map label for this gene is sasA [H]

Identifier: 158335654

GI number: 158335654

Start: 2528589

End: 2529761

Strand: Reverse

Name: sasA [H]

Synonym: AM1_2504

Alternate gene names: 158335654

Gene position: 2529761-2528589 (Counterclockwise)

Preceding gene: 158335655

Following gene: 158335653

Centisome position: 38.9

GC content: 46.46

Gene sequence:

>1173_bases
ATGAGATCATCTTCCGAGACCCCCACTGACCATCTACAATCTGTAGTTAAGTCGGATGCTTCACTACAGCTGCTGTTGTT
TGTGGATAAACGTACAACGGCTAAAGAACAGATTCTCCAAATATCGAAATATTTAGATACCCTAAAACCAGACTGTGACT
TTGATTTGCATGTAGTTGAAGTCTCTGAACAACCCTATCTGGTTGAATACTACAAACTGGTGGCGACGCCAGCATTAGTT
AAAATTCGGCCTGAGCCGCGACATATTTTGGCAGGCAGCAACTTGGTTTCTCAGTTGGAAGAGTCCTGGCCCTATTGGCA
GCATGCCCTCTCGGCGAATGATCTGCTGGATGACCAACTGAATGTAGAGGAAGATACAACCTCCTTTGCTGACGCTGCGC
AACTGATGCAGCTTTCGGATCAAATGTTTCGTCTGCGACAAGAGAATGAAGCCTTGCAGGATCAGCTCAAGTTCAAGGAT
CGCATGATTAACATGTTGGCCCATGATCTTCGTAATCCATTAACGGCGGCGACCATTGCGTTAGAGACTTTAGCGGGACA
ATGGGATGAGGACAATGAGGTCATTCGAAATTTATCTTCAGCTTTGCTGCAACGCTTGACGAAACATGCTCATGCCCAAA
CCCAAATTATTGAGCGCATGATCACCAATTTGCTAGAGGCCTCTCAAGGGAGTGAACCCGACCTCAAAACTCATCCTAAG
CAGCTGGACTTGGGGGGACTGTGCCAAGAAATTGCTTTGAGGGTCCAAAATGCTCTTAAAGCTAAATCCCAGACTTTGAA
GAGTGATATCCCACCTGATATCCCCAATGTTCATGCCGATGCCGATCAAGTGCAGCAGGTGATTCTTAACTTGCTGGATA
ATGCGATGAAATATACGCCAGAGGGTGGAGAAATTCAACTTTTAGTTTTGCATCGCACGACGCAAAAGGTGCAGGTTAGT
ATTTGCGACAATGGCTTAGGGATTCCCCAGGAAAAGCAGCAATATATTTTTGATAACCAGTATCGCCTAGATCGGGATCA
AGACGAGTCAGGATATGGCATGGGGTTAGCCCACTGCAAACGGATTGTGGGGAACCACTATGGTGAAATTTGGGTGGATT
CTGCGCCCAATCACGGCAGCTCTTTCCACTTTACGCTGCCCGTTTATCGTTGA

Upstream 100 bases:

>100_bases
CATTGTCAATTAATATGAAGTTAAATCAGTATGTGTGAGTCACTCATTGGTATCTTCTGACTAACTCCCATGCCTATTCT
GTTCTGATCTGATCACCGGA

Downstream 100 bases:

>100_bases
TATGGATCCCAAAATGTCACTAGATGAACGATAAAGTTATCAATTTTGATAACAGTTATAAAATTTTATAGATTTTGGCA
TAGGACTGCACCAAGACCAT

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRSSSETPTDHLQSVVKSDASLQLLLFVDKRTTAKEQILQISKYLDTLKPDCDFDLHVVEVSEQPYLVEYYKLVATPALV
KIRPEPRHILAGSNLVSQLEESWPYWQHALSANDLLDDQLNVEEDTTSFADAAQLMQLSDQMFRLRQENEALQDQLKFKD
RMINMLAHDLRNPLTAATIALETLAGQWDEDNEVIRNLSSALLQRLTKHAHAQTQIIERMITNLLEASQGSEPDLKTHPK
QLDLGGLCQEIALRVQNALKAKSQTLKSDIPPDIPNVHADADQVQQVILNLLDNAMKYTPEGGEIQLLVLHRTTQKVQVS
ICDNGLGIPQEKQQYIFDNQYRLDRDQDESGYGMGLAHCKRIVGNHYGEIWVDSAPNHGSSFHFTLPVYR

Sequences:

>Translated_390_residues
MRSSSETPTDHLQSVVKSDASLQLLLFVDKRTTAKEQILQISKYLDTLKPDCDFDLHVVEVSEQPYLVEYYKLVATPALV
KIRPEPRHILAGSNLVSQLEESWPYWQHALSANDLLDDQLNVEEDTTSFADAAQLMQLSDQMFRLRQENEALQDQLKFKD
RMINMLAHDLRNPLTAATIALETLAGQWDEDNEVIRNLSSALLQRLTKHAHAQTQIIERMITNLLEASQGSEPDLKTHPK
QLDLGGLCQEIALRVQNALKAKSQTLKSDIPPDIPNVHADADQVQQVILNLLDNAMKYTPEGGEIQLLVLHRTTQKVQVS
ICDNGLGIPQEKQQYIFDNQYRLDRDQDESGYGMGLAHCKRIVGNHYGEIWVDSAPNHGSSFHFTLPVYR
>Mature_390_residues
MRSSSETPTDHLQSVVKSDASLQLLLFVDKRTTAKEQILQISKYLDTLKPDCDFDLHVVEVSEQPYLVEYYKLVATPALV
KIRPEPRHILAGSNLVSQLEESWPYWQHALSANDLLDDQLNVEEDTTSFADAAQLMQLSDQMFRLRQENEALQDQLKFKD
RMINMLAHDLRNPLTAATIALETLAGQWDEDNEVIRNLSSALLQRLTKHAHAQTQIIERMITNLLEASQGSEPDLKTHPK
QLDLGGLCQEIALRVQNALKAKSQTLKSDIPPDIPNVHADADQVQQVILNLLDNAMKYTPEGGEIQLLVLHRTTQKVQVS
ICDNGLGIPQEKQQYIFDNQYRLDRDQDESGYGMGLAHCKRIVGNHYGEIWVDSAPNHGSSFHFTLPVYR

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=278, Percent_Identity=29.136690647482, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=25.609756097561, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=26.4, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.5123966942149, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=24.9122807017544, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=26.5232974910394, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=291, Percent_Identity=26.4604810996564, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994928, Length=258, Percent_Identity=23.2558139534884, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=272, Percent_Identity=27.2058823529412, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=301, Percent_Identity=25.9136212624585, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=224, Percent_Identity=29.4642857142857, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=26.8085106382979, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 44195; Mature: 44195

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSSETPTDHLQSVVKSDASLQLLLFVDKRTTAKEQILQISKYLDTLKPDCDFDLHVVE
CCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VSEQPYLVEYYKLVATPALVKIRPEPRHILAGSNLVSQLEESWPYWQHALSANDLLDDQL
ECCCCHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHHCCCHHHHHCCHHHHCCCCC
NVEEDTTSFADAAQLMQLSDQMFRLRQENEALQDQLKFKDRMINMLAHDLRNPLTAATIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LETLAGQWDEDNEVIRNLSSALLQRLTKHAHAQTQIIERMITNLLEASQGSEPDLKTHPK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QLDLGGLCQEIALRVQNALKAKSQTLKSDIPPDIPNVHADADQVQQVILNLLDNAMKYTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
EGGEIQLLVLHRTTQKVQVSICDNGLGIPQEKQQYIFDNQYRLDRDQDESGYGMGLAHCK
CCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
RIVGNHYGEIWVDSAPNHGSSFHFTLPVYR
HHHCCCCCCEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRSSSETPTDHLQSVVKSDASLQLLLFVDKRTTAKEQILQISKYLDTLKPDCDFDLHVVE
CCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VSEQPYLVEYYKLVATPALVKIRPEPRHILAGSNLVSQLEESWPYWQHALSANDLLDDQL
ECCCCHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHHCCCHHHHHCCHHHHCCCCC
NVEEDTTSFADAAQLMQLSDQMFRLRQENEALQDQLKFKDRMINMLAHDLRNPLTAATIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LETLAGQWDEDNEVIRNLSSALLQRLTKHAHAQTQIIERMITNLLEASQGSEPDLKTHPK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QLDLGGLCQEIALRVQNALKAKSQTLKSDIPPDIPNVHADADQVQQVILNLLDNAMKYTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
EGGEIQLLVLHRTTQKVQVSICDNGLGIPQEKQQYIFDNQYRLDRDQDESGYGMGLAHCK
CCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
RIVGNHYGEIWVDSAPNHGSSFHFTLPVYR
HHHCCCCCCEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA