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The map label for this gene is insK [C]

Identifier: 158335556

GI number: 158335556

Start: 2409272

End: 2410129

Strand: Direct

Name: insK [C]

Synonym: AM1_2404

Alternate gene names: 158335556

Gene position: 2409272-2410129 (Clockwise)

Preceding gene: 158335555

Following gene: 158335558

Centisome position: 37.04

GC content: 48.83

Gene sequence:

>858_bases
ATGGTGAGACAGTTGCAGCAGGACTATTCCATTCGCCAAATTTGTCAGGTACTCAATTACCCACGCTCTCAAGTGTATTA
CCATGCCAGAGGCCAACCGGATGAGAGCGAACTAAAAGCGGCCATTGCTGGAGTTGCTGGAGCCTATCCGACTTATGGCT
ATCGTCGAATCACCGCCCAACTGCAGCGTCAGGGGTATTGCGTTAACCATAAACGCGTGGCTCGACTAATGCGACAGATA
GGGATTATGGCCAAGACCAAAGTCAAACGCAAACGCACCACCAATAGCGAACATTCGTTCCCTCGCTATGGCAATCGAGT
GTTGAATCTCTCCATCGACCATCCTGAGCAGGTGTGGGTGGCGGACATCACGTACATTCGCTTACAGCAGGAGTTTGTCT
ATTTGGCCGTCGTGATGGATGTCTTTACTCGCGCCATTCGTGGCTGGCATCTGTCCCGCCATATCGACCAGCAACTAACG
TTGAGGGCGTTGAACAAGGCGTTGGAGCGGGCAACGCCTGAGATTCACCATTCTGACCAAGGGGTTCAGTATGCCGCTGC
AGCCTATATGCAATTGCTCCAACAACACCAAGTGCAAATCAGTATGGCCGAGGTGGGACAGGCTTGGCAAAATGGCTATG
CTGAGCGATTGATGAGAACGATAAAAGAAGAAGAGGTCGATTTATCAGACTATCGAAATTTTACTGAAGCGTATGAGCAC
ATTGAGCAGTTTCTAGAAGATGTGTATATGCATAAGCGGATTCATTCATCACTGGGGTATTTGACACCCTGTGAATATGA
GCAGCAGTGGAGACAACAGAACAATCACTATTGTATGAATAAGGAGGATAGCGCTTAA

Upstream 100 bases:

>100_bases
CGAAAATTGCTCAGTTAGAGCGTCTAGTCGGCCAATTGACGCTGCAATTAGAGATCGCAAAAAAAGCCTCAATGTCCTTA
CACCTAACCAAAAACGGCAG

Downstream 100 bases:

>100_bases
TTCATCTATTGCCCTGTCCGAATATAGGGGTTCACGTCATCGCCTAACACCAGCAGTCATCGTTGCCCGATGTAATGCTT
GACTCACCAGTACTCTGCCA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MVRQLQQDYSIRQICQVLNYPRSQVYYHARGQPDESELKAAIAGVAGAYPTYGYRRITAQLQRQGYCVNHKRVARLMRQI
GIMAKTKVKRKRTTNSEHSFPRYGNRVLNLSIDHPEQVWVADITYIRLQQEFVYLAVVMDVFTRAIRGWHLSRHIDQQLT
LRALNKALERATPEIHHSDQGVQYAAAAYMQLLQQHQVQISMAEVGQAWQNGYAERLMRTIKEEEVDLSDYRNFTEAYEH
IEQFLEDVYMHKRIHSSLGYLTPCEYEQQWRQQNNHYCMNKEDSA

Sequences:

>Translated_285_residues
MVRQLQQDYSIRQICQVLNYPRSQVYYHARGQPDESELKAAIAGVAGAYPTYGYRRITAQLQRQGYCVNHKRVARLMRQI
GIMAKTKVKRKRTTNSEHSFPRYGNRVLNLSIDHPEQVWVADITYIRLQQEFVYLAVVMDVFTRAIRGWHLSRHIDQQLT
LRALNKALERATPEIHHSDQGVQYAAAAYMQLLQQHQVQISMAEVGQAWQNGYAERLMRTIKEEEVDLSDYRNFTEAYEH
IEQFLEDVYMHKRIHSSLGYLTPCEYEQQWRQQNNHYCMNKEDSA
>Mature_285_residues
MVRQLQQDYSIRQICQVLNYPRSQVYYHARGQPDESELKAAIAGVAGAYPTYGYRRITAQLQRQGYCVNHKRVARLMRQI
GIMAKTKVKRKRTTNSEHSFPRYGNRVLNLSIDHPEQVWVADITYIRLQQEFVYLAVVMDVFTRAIRGWHLSRHIDQQLT
LRALNKALERATPEIHHSDQGVQYAAAAYMQLLQQHQVQISMAEVGQAWQNGYAERLMRTIKEEEVDLSDYRNFTEAYEH
IEQFLEDVYMHKRIHSSLGYLTPCEYEQQWRQQNNHYCMNKEDSA

Specific function: Involved in the transposition of the insertion sequence is150 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=205, Percent_Identity=36.0975609756098, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1789981, Length=278, Percent_Identity=31.294964028777, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788405, Length=281, Percent_Identity=29.8932384341637, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787263, Length=281, Percent_Identity=29.8932384341637, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786753, Length=281, Percent_Identity=29.8932384341637, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786570, Length=281, Percent_Identity=29.8932384341637, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786490, Length=281, Percent_Identity=29.8932384341637, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790724, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789424, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789224, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788305, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787669, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786558, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33630; Mature: 33630

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQLQQDYSIRQICQVLNYPRSQVYYHARGQPDESELKAAIAGVAGAYPTYGYRRITAQ
CCCHHHHCCCHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
LQRQGYCVNHKRVARLMRQIGIMAKTKVKRKRTTNSEHSFPRYGNRVLNLSIDHPEQVWV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHH
ADITYIRLQQEFVYLAVVMDVFTRAIRGWHLSRHIDQQLTLRALNKALERATPEIHHSDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GVQYAAAAYMQLLQQHQVQISMAEVGQAWQNGYAERLMRTIKEEEVDLSDYRNFTEAYEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IEQFLEDVYMHKRIHSSLGYLTPCEYEQQWRQQNNHYCMNKEDSA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVRQLQQDYSIRQICQVLNYPRSQVYYHARGQPDESELKAAIAGVAGAYPTYGYRRITAQ
CCCHHHHCCCHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
LQRQGYCVNHKRVARLMRQIGIMAKTKVKRKRTTNSEHSFPRYGNRVLNLSIDHPEQVWV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHH
ADITYIRLQQEFVYLAVVMDVFTRAIRGWHLSRHIDQQLTLRALNKALERATPEIHHSDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GVQYAAAAYMQLLQQHQVQISMAEVGQAWQNGYAERLMRTIKEEEVDLSDYRNFTEAYEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IEQFLEDVYMHKRIHSSLGYLTPCEYEQQWRQQNNHYCMNKEDSA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]