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The map label for this gene is siaT [H]

Identifier: 158335506

GI number: 158335506

Start: 2355726

End: 2357090

Strand: Direct

Name: siaT [H]

Synonym: AM1_2354

Alternate gene names: 158335506

Gene position: 2355726-2357090 (Clockwise)

Preceding gene: 158335505

Following gene: 158335507

Centisome position: 36.22

GC content: 49.82

Gene sequence:

>1365_bases
ATGGACTATAACTGGCTAAGCCTAGCCATGTTTGTGGTCGCCCTAGGCCTGCTGTCGGCAGGTTATCCGGTGGCCTTTAC
CTTGAGTGGCGTGGCCCTTTTATTTTGCATGCTACCCACAGCTATCAGTTGGGTCGATCCAGAAATTTTGGTGGATCCCA
ATCTGCTAGCCATGCCTCAAGAAATTTTCGCCACCATGCTGAGCAATACGCTCCTGGCAATTCCCTACTTTATTTTTATG
GGGGCCATGCTGGAGAAATCAGGTTTGGCTGAGAAACTGCTCGAAACCATCGGTATTCTCTTTGGGCCGATTCGGGGTGG
ACTCGCTTTGGCCGTGGTATTTGTGGGGGCTTTGCTGGCGGCGACCACGGGCGTGGTCGCCGCCTCTGTCGTCGCCATGG
GTCTTATCTCTCTACCGATCATGCTCCGCTACAACTACAGTAAGGAGCTGACGGCTGGGGTCATTGTCGCTTCTGGGACT
TTGGGGCAAATTATCCCTCCCAGTGTGGTGCTAGTGGTGTTGGGTGATCAACTGGGGGTTCCAGTCGGCGACTTATTTCT
GGGCGCTTTGATTCCAGGCTTAATGATTGCTGGGATGTTTGCCCTGCACATTATCATTGTTGCCATCTTTAAACCCGAAG
CCGCTCCTGCTTTACCCCTCTCGGTCCGGGAAATTCAGGGGAAAGAGCTAGCCCTTCGAGTGATCAAAGTTTTAATTCCA
CCCCTAGCCCTAATTTTCTTGGTTTTGGGCAGTATCTTTTGGGGCATTGCAACGCCCACAGAAGCAGGCGCATTGGGGGC
ATTAGGAGCGATTATTTTGGCCTGGGCCAATGGTGAGTTTTCCCTAAAACGGCTGTTTGAGGTGTCAGAGTCTACCCTGC
GCATCACCAGCATGGTGATGCTGATTCTGATCGGTTCTCGGGCTTTTAGTCTCGTCTTTATTGGTTTAGGCGGAAATGTT
CTAGTTTCTGATGCACTGCAAAATCTACCAGGTGGCGAACTCAGCTTCTTAATCGTCAGTATGCTGACGGTATTTTTGCT
GGGTTTCTTTATCGACTTTTTTCAAATTGCTTTTATCGTGGTGCCTATTTTTCGGCCCATTGCCCAGGCATTGGGCATGG
ACTTGCTATGGTATGGCATTTTGCTAGGGGTCAATTTACAGACCTCCTTTTTAACCCCTCCCTTTGGTTTTGCGTTGTTC
TATTTAAGGGGGGTCGCACCGCCAGAGATCAAAACGTCAGACATTTATCGCGGGGCCATCCCTTTTATCATCTTGCAACT
AATTGTGCTGGTCATTTTGGTTCAATTCCCGGAGATCGTAACGTTTTTACCCTCGTTAAAGACAACGCCAACTGGTTCTG
TCTAG

Upstream 100 bases:

>100_bases
ATCTTCTTTGTGCTGCTTTTACTGCAAGGCATTTCAGAAGCCATTAAAAATGGGATCAAACTGAGACGGTTCAGCCTAGG
CCAAGAAGGAGAAGCCGACC

Downstream 100 bases:

>100_bases
TTTTTATGTAAAAGAATAAAATTTTAGCCCCAATGATGCCCTATTACAGGTAATTGGGAATACTAAGAGTTAATCGGCAA
ATAGGTTAGAGTACGATGCG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MDYNWLSLAMFVVALGLLSAGYPVAFTLSGVALLFCMLPTAISWVDPEILVDPNLLAMPQEIFATMLSNTLLAIPYFIFM
GAMLEKSGLAEKLLETIGILFGPIRGGLALAVVFVGALLAATTGVVAASVVAMGLISLPIMLRYNYSKELTAGVIVASGT
LGQIIPPSVVLVVLGDQLGVPVGDLFLGALIPGLMIAGMFALHIIIVAIFKPEAAPALPLSVREIQGKELALRVIKVLIP
PLALIFLVLGSIFWGIATPTEAGALGALGAIILAWANGEFSLKRLFEVSESTLRITSMVMLILIGSRAFSLVFIGLGGNV
LVSDALQNLPGGELSFLIVSMLTVFLLGFFIDFFQIAFIVVPIFRPIAQALGMDLLWYGILLGVNLQTSFLTPPFGFALF
YLRGVAPPEIKTSDIYRGAIPFIILQLIVLVILVQFPEIVTFLPSLKTTPTGSV

Sequences:

>Translated_454_residues
MDYNWLSLAMFVVALGLLSAGYPVAFTLSGVALLFCMLPTAISWVDPEILVDPNLLAMPQEIFATMLSNTLLAIPYFIFM
GAMLEKSGLAEKLLETIGILFGPIRGGLALAVVFVGALLAATTGVVAASVVAMGLISLPIMLRYNYSKELTAGVIVASGT
LGQIIPPSVVLVVLGDQLGVPVGDLFLGALIPGLMIAGMFALHIIIVAIFKPEAAPALPLSVREIQGKELALRVIKVLIP
PLALIFLVLGSIFWGIATPTEAGALGALGAIILAWANGEFSLKRLFEVSESTLRITSMVMLILIGSRAFSLVFIGLGGNV
LVSDALQNLPGGELSFLIVSMLTVFLLGFFIDFFQIAFIVVPIFRPIAQALGMDLLWYGILLGVNLQTSFLTPPFGFALF
YLRGVAPPEIKTSDIYRGAIPFIILQLIVLVILVQFPEIVTFLPSLKTTPTGSV
>Mature_454_residues
MDYNWLSLAMFVVALGLLSAGYPVAFTLSGVALLFCMLPTAISWVDPEILVDPNLLAMPQEIFATMLSNTLLAIPYFIFM
GAMLEKSGLAEKLLETIGILFGPIRGGLALAVVFVGALLAATTGVVAASVVAMGLISLPIMLRYNYSKELTAGVIVASGT
LGQIIPPSVVLVVLGDQLGVPVGDLFLGALIPGLMIAGMFALHIIIVAIFKPEAAPALPLSVREIQGKELALRVIKVLIP
PLALIFLVLGSIFWGIATPTEAGALGALGAIILAWANGEFSLKRLFEVSESTLRITSMVMLILIGSRAFSLVFIGLGGNV
LVSDALQNLPGGELSFLIVSMLTVFLLGFFIDFFQIAFIVVPIFRPIAQALGMDLLWYGILLGVNLQTSFLTPPFGFALF
YLRGVAPPEIKTSDIYRGAIPFIILQLIVLVILVQFPEIVTFLPSLKTTPTGSV

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=432, Percent_Identity=26.6203703703704, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48291; Mature: 48291

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYNWLSLAMFVVALGLLSAGYPVAFTLSGVALLFCMLPTAISWVDPEILVDPNLLAMPQ
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHCCH
EIFATMLSNTLLAIPYFIFMGAMLEKSGLAEKLLETIGILFGPIRGGLALAVVFVGALLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTGVVAASVVAMGLISLPIMLRYNYSKELTAGVIVASGTLGQIIPPSVVLVVLGDQLGV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCHHEEEEECCCCCC
PVGDLFLGALIPGLMIAGMFALHIIIVAIFKPEAAPALPLSVREIQGKELALRVIKVLIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHH
PLALIFLVLGSIFWGIATPTEAGALGALGAIILAWANGEFSLKRLFEVSESTLRITSMVM
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
LILIGSRAFSLVFIGLGGNVLVSDALQNLPGGELSFLIVSMLTVFLLGFFIDFFQIAFIV
HHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIFRPIAQALGMDLLWYGILLGVNLQTSFLTPPFGFALFYLRGVAPPEIKTSDIYRGAI
HHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
PFIILQLIVLVILVQFPEIVTFLPSLKTTPTGSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDYNWLSLAMFVVALGLLSAGYPVAFTLSGVALLFCMLPTAISWVDPEILVDPNLLAMPQ
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHCCH
EIFATMLSNTLLAIPYFIFMGAMLEKSGLAEKLLETIGILFGPIRGGLALAVVFVGALLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTGVVAASVVAMGLISLPIMLRYNYSKELTAGVIVASGTLGQIIPPSVVLVVLGDQLGV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCHHEEEEECCCCCC
PVGDLFLGALIPGLMIAGMFALHIIIVAIFKPEAAPALPLSVREIQGKELALRVIKVLIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHH
PLALIFLVLGSIFWGIATPTEAGALGALGAIILAWANGEFSLKRLFEVSESTLRITSMVM
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
LILIGSRAFSLVFIGLGGNVLVSDALQNLPGGELSFLIVSMLTVFLLGFFIDFFQIAFIV
HHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIFRPIAQALGMDLLWYGILLGVNLQTSFLTPPFGFALFYLRGVAPPEIKTSDIYRGAI
HHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
PFIILQLIVLVILVQFPEIVTFLPSLKTTPTGSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]